Neural stem cells injured by oxidative stress can be rejuvenated by GV1001, a novel peptide, through scavenging free radicals and enhancing survival signals

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hTERT peptide fragment GV1001 demonstrates radioprotective and antifibrotic effects through suppression of TGF‑β signaling

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The Novel Peptide Vaccine GV1001 Protects Hearing in a Kanamycin-induced Ototoxicity Mouse Model

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GV1001, hTERT Peptide Fragment, Prevents Doxorubicin-Induced Endothelial-to-Mesenchymal Transition in Human Endothelial Cells and Atherosclerosis in Mice

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Neural Stem Cell Death Mechanisms Induced by Amyloid Beta

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Ascorbic acid mitigates the impact of oxidative stress in a human model of febrile seizure and mesial temporal lobe epilepsy

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Progressive Supranuclear Palsy

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Pathophysiology of Alzheimer’s Disease: Focus on H3 Receptor Modulators and Their Implications

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Effects of GV1001 on Language Dysfunction in Patients With Moderate-to-Severe Alzheimer’s Disease: Post Hoc Analysis of Severe Impairment Battery Subscales

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GV1001, an hTERT-Derived Peptide, Prevents Cisplatin-Induced Nephrotoxicity by Preserving Mitochondrial Function

Chen, W., Beheshtian, C., Kim, S., Kim, S., Kim, S., & Park, N.-H. (2025) · Cells · doi:10.3390/cells14221818 · Cited by 2 · see citing works

GV1001 reduces neurodegeneration and prolongs lifespan in 3xTg-AD mouse model through anti-aging effects

Park, H., Kwon, H. S., Lee, K., Kim, Y. E., Son, J., Choi, N.-Y., Han, M., Park, D. W., Kim, S., & Koh, S. (2024) · Aging · doi:10.18632/aging.205489 · Cited by 2 · see citing works

Therapeutic effects of telomerase-derived peptide GV1001 in experimental autoimmune encephalomyelitis: Inhibiting neuroinflammation and promoting remyelination

Kim, J.-H., Bhusal, A., Kwon, J., Lee, J.-Y., Song, M., Lee, W., Zheng, L. T., Kim, S., & Suk, K. (2025) · Biochemical Pharmacology · doi:10.1016/j.bcp.2025.117514 · Cited by 1 · see citing works

GV1001 reduces pathological 4R tau and functional deficits in models relevant to progressive supranuclear palsy

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GV1001: repurposing a telomerase-derived peptide for neurological therapeutics

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Retrospective Analysis of the Clinical Characteristics of Patients with Breast Cancer Treated with Telomerase Peptide Immunotherapy Combined with Cytotoxic Chemotherapy

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New Perspectives for Treatment in Alzheimer’s Disease

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Age-related disease: Effective intervention

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Additional file 2 of Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer’s disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial

Koh, S.-H., Kwon, H. S., Choi, S. H., Jeong, J. H., Na, H. R., Lee, C. N., Yang, Y., Lee, A. Y., Lee, J.-H., Park, K. W., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14329456

Additional file 1 of Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer’s disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial

Koh, S.-H., Kwon, H. S., Choi, S. H., Jeong, J. H., Na, H. R., Lee, C. N., Yang, Y., Lee, A. Y., Lee, J.-H., Park, K. W., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14329453

GV1001, hTERT Peptide Fragment, Prevents 5-Fluorouracil-Induced Mucositis by Inhibiting Mitochondrial Damages

Beheshtian, C., Chen, W., Kim, S., Jun, A., Bae, E., Kim, R., Kim, S., & Park, N.-H. (2026) · Cells · doi:10.3390/cells15090774

A human telomerase reverse transcriptase-derived peptide GV1001 rescues neurodegeneration in a mouse model of Alzheimer disease

Lee, Y., Nam, H., Lee, J. D., Ko, Y. J., Kim, E. J., Ha, S., Kim, N., Koo, J. W., Son, T., Kim, S., et al. (2026) · Experimental & Molecular Medicine · doi:10.1038/s12276-026-01729-9

Serendipitous Discovery of Short Peptides Dimethylammonium Salt Promoting Neural Differentiation

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The novel vaccine peptide GV1001 effectively blocks β-amyloid toxicity by mimicking the extra-telomeric functions of human telomerase reverse transcriptase

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