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Creatine improves health and survival of mice
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“In a model of aged mice, CrM tended to reduce reactive oxygen species in the brain, reduced “lipofuscin,” which is considered an aging pigment, upregulated genes associated with neuronal growth, neuroprotection, and learning, and tended to improve function on a locomotor task (p = 0.054) [121].”
From Creatine monohydrate supplementation for older adults and clinical populations (2025) · cites this paper as [121]
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Direct antioxidant properties of creatine
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Pericytes regulate the blood–brain barrier
Armulik, A., Genové, G., Mäe, M., Nisancioglu, M. H., Wallgard, E., Niaudet, C., He, L., Norlin, J., Lindblom, P., Strittmatter, K., et al. (2010) · Nature · doi:10.1038/nature09522 · Cited by 2,843
The creatine kinase system and pleiotropic effects of creatine
Wallimann, T., Tokarska-Schlattner, M., & Schlattner, U. (2011) · Amino Acids · doi:10.1007/s00726-011-0877-3 · Cited by 797
Mitochondrial Approaches for Neuroprotection
Chaturvedi, R. K., & Beal, M. F. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1427.027 · Cited by 294
Exploring the therapeutic role of creatine supplementation
Gualano, B., Artioli, G. G., Poortmans, J. R., & Lancha Junior, A. H. (2010) · Amino Acids · doi:10.1007/s00726-009-0263-6 · Cited by 156
Candow, D. G., Forbes, S. C., Chilibeck, P. D., Cornish, S. M., Antonio, J., & Kreider, R. B. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8040488 · Cited by 149
Metadata
- Authors
- Bender, A., Beckers, J., Schneider, I., Hölter, S. M., Haack, T., Ruthsatz, T., Vogt-Weisenhorn, D. M., Becker, L., Genius, J., Rujescu, D., Irmler, M., Mijalski, T., Mader, M., Quintanilla-Martinez, L., Fuchs, H., Gailus-Durner, V., de Angelis, M. H., Wurst, W., Schmidt, J., & Klopstock, T.
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 2008-09
- Volume
- 29
- Issue
- 9
- Pages
- 1404-1411
- ISSN
- 0197-4580
- Cited by
- 81
- References
- 7
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
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- Bender, A., Beckers, J., Schneider, I., Hölter, S. M., Haack, T., Ruthsatz, T., Vogt-Weisenhorn, D. M., Becker, L., Genius, J., Rujescu, D., Irmler, M., Mijalski, T., Mader, M., Quintanilla-Martinez, L., Fuchs, H., Gailus-Durner, V., de Angelis, M. H., Wurst, W., Schmidt, J., & Klopstock, T. (2008). Creatine improves health and survival of mice. Neurobiology of Aging. https://doi.org/10.1016/j.neurobiolaging.2007.03.001
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.