A central source of movement variability
Open accessAbstract
Movements are universally, sometimes frustratingly, variable. When such variability causes error, we typically assume that something went wrong during the movement. The same assumption is made by recent and influential models of motor control. These posit that the principal limit on repeatable performance is neuromuscular noise that corrupts movement as it occurs. An alternative hypothesis is that movement variability arises before movements begin, during motor preparation. We examined this possibility directly by recording the preparatory activity of single cortical neurons during a highly practiced reach task. Small variations in preparatory neural activity were predictive of small variations in the upcoming reach. Effect magnitudes were such that at least half of the observed movement variability likely had its source during motor preparation. Thus, even for a highly practiced task, the ability to repeatedly plan the same movement limits our ability to repeatedly execute the same movement.
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There is evidence for a trial-to-trial correlation between the response latency and the preparatory activity of cortical movement neurons, before the target onset, in saccade and other sensory-motor tasks.
“There is also evidence for a trial-to-trial correlation between the response latency and the preparatory activity of cortical movement neurons, before the target onset, in saccade and other sensory-motor tasks (Dorris et al., 1997; Churchland et al., 2006; Nakahara et al., 2006).”
From Decision Making in Recurrent Neuronal Circuits (2008) · cites this paper as Churchland et al., 2006
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- Authors
- Churchland, M. M., Afshar, A., & Shenoy, K. V.
- Affiliations
- Stanford University (US)
- Corresponding author
- Shenoy, Krishna V.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2006-12
- Volume
- 52
- Issue
- 6
- Pages
- 1085-1096
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC1941679
- OpenAlex
- W1998425584
- Cited by
- 393
- References
- 42
- Citations by year
- 2026: 15 · 2025: 27 · 2024: 16 · 2023: 23 · 2022: 18 · 2021: 18 · 2020: 22 · 2019: 16 · 2018: 27 · 2017: 27 · 2016: 22 · 2015: 20 · 2014: 33 · 2013: 20 · 2012: 24
- FWCI
- 5.10
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 2420 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Neurological Disorders and Stroke (T32NS007158)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- movement variability, motor preparation, motor control, cortical neurons, single-unit recording, motor planning, motor errors
- MeSH terms
- Animals, Behavior, Animal, Biomechanical Phenomena, Cell Count, Electromyography, Macaca mulatta, Male, Motor Cortex, Movement, Neurons, Psychomotor Performance, Reaction Time, Regression, Psychology, Evoked Potentials, Motor
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