The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
The Neural Substrate of Spectral Preference in Drosophila
Open accessAbstract
Drosophila vision is mediated by inputs from three types of photoreceptor neurons; R1-R6 mediate achromatic motion detection, while R7 and R8 constitute two chromatic channels. Neural circuits for processing chromatic information are not known. Here, we identified the first-order interneurons downstream of the chromatic channels. Serial EM revealed that small-field projection neurons Tm5 and Tm9 receive direct synaptic input from R7 and R8, respectively, and indirect input from R1-R6, qualifying them to function as color-opponent neurons. Wide-field Dm8 amacrine neurons receive input from 13-16 UV-sensing R7s and provide output to projection neurons. Using a combinatorial expression system to manipulate activity in different neuron subtypes, we determined that Dm8 neurons are necessary and sufficient for flies to exhibit phototaxis toward ultraviolet instead of green light. We propose that Dm8 sacrifices spatial resolution for sensitivity by relaying signals from multiple R7s to projection neurons, which then provide output to higher visual centers.
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“The vast majority of these types are based on previous literature42,93–99.”
From Whole-brain annotation and multi-connectome cell typing of Drosophila (2024) · cites this paper as [99]
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Kitamoto, T. (2001) · Journal of Neurobiology · doi:10.1002/neu.1018 · Cited by 868
Genetic Dissection of Neural Circuits
Luo, L., Callaway, E. M., & Svoboda, K. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.002 · Cited by 771
The optic lobe of Drosophila melanogaster. I. A Golgi analysis of wild-type structure
Fischbach, K.-F., & Dittrich, A. P. M. (1989) · Cell and Tissue Research · doi:10.1007/bf00218858 · Cited by 709
Spatial Representation of the Glomerular Map in the Drosophila Protocerebrum
Wong, A. M., Wang, J. W., & Axel, R. (2002) · Cell · doi:10.1016/s0092-8674(02)00707-9 · Cited by 560
Self-citationThe Drosophila ninaE gene encodes an opsin
O’Tousa, J. E., Baehr, W., Martin, R. L., Hirsh, J., Pak, W. L., & Applebury, M. (1985) · Cell · doi:10.1016/0092-8674(85)90343-5 · Cited by 540
Luan, H., Peabody, N. C., Vinson, C. R., & White, B. H. (2006) · Neuron · doi:10.1016/j.neuron.2006.08.028 · Cited by 500
Self-citationCronly-Dillon, J. R. (1991) · UCL Discovery (University College London) · Cited by 481
Extreme Diversity among Amacrine Cells: Implications for Function
MacNeil, M. A., & Masland, R. H. (1998) · Neuron · doi:10.1016/s0896-6273(00)80478-x · Cited by 472
Synaptic organization of columnar elements in the lamina of the wild type in Drosophila melanogaster
Meinertzhagen, I. A., & O'Neil, S. D. (1991) · Journal of Comparative Neurology · doi:10.1002/cne.903050206 · Cited by 403
Self-citationYoshida, K., Watanabe, D., Ishikane, H., Tachibana, M., Pastan, I. H., & Nakanishi, S. (2001) · Neuron · doi:10.1016/s0896-6273(01)00316-6 · Cited by 363
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Nern, A., Pfeiffer, B. D., & Rubin, G. M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1506763112 · Cited by 584
Design Principles of Insect and Vertebrate Visual Systems
Sanes, J. R., & Zipursky, S. L. (2010) · Neuron · doi:10.1016/j.neuron.2010.01.018 · Cited by 584
Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly
Venken, K. J. T., Simpson, J. H., & Bellen, H. J. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.021 · Cited by 463
Whole-brain annotation and multi-connectome cell typing of Drosophila
Schlegel, P., Yin, Y., Bates, A. S., Dorkenwald, S., Eichler, K., Brooks, P., Han, D. S., Gkantia, M., dos Santos, M., Munnelly, E. J., et al. (2024) · Nature · doi:10.1038/s41586-024-07686-5 · Cited by 413
“The vast majority of these types are based on previous literature 42,93–99 .”
BackgroundON and OFF pathways in Drosophila motion vision
Joesch, M., Schnell, B., Raghu, S. V., Reiff, D. F., & Borst, A. (2010) · Nature · doi:10.1038/nature09545 · Cited by 352
Metadata
- Authors
- Gao, S., Takemura, S.-Y., Ting, C.-Y., Huang, S., Lu, Z., Luan, H., Rister, J., Thum, A. S., Yang, M., Hong, S.-T., Wang, J. W., Odenwald, W. F., White, B. H., Meinertzhagen, I. A., & Lee, C.-H.
- Affiliations
- National Institutes of Health (US)
- Dalhousie University (CA)
- University of Würzburg (DE)
- Korea Advanced Institute of Science and Technology (KR)
- University of California San Diego (US)
- Corresponding author
- Meinertzhagen, Ian A.
- Lee, Chi-Hon
- ORCID
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2008-10
- Volume
- 60
- Issue
- 2
- Pages
- 328-342
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC2665173
- OpenAlex
- W2113540611
- Cited by
- 284
- References
- 54
- Citations by year
- 2026: 9 · 2025: 17 · 2024: 17 · 2023: 14 · 2022: 10 · 2021: 16 · 2020: 22 · 2019: 24 · 2018: 16 · 2017: 14 · 2016: 13 · 2015: 18 · 2014: 21 · 2013: 13 · 2012: 17
- FWCI
- 5.90
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- KOPS (University of Konstanz) (submittedVersion)
- Funders
- National Institutes of Health
- National Eye Institute (EY-03592, R01EY003592)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (Z01HD008776, Z01HD008748, HD008748-03)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- neural circuits, serial electron microscopy
- MeSH terms
- Animals, Drosophila melanogaster, Interneurons, Synaptic Transmission, Optic Lobe, Nonmammalian, Photic Stimulation, Synapses, Ultraviolet Rays, Visual Pathways, Photoreceptor Cells, Invertebrate, Amacrine Cells, Compound Eye, Arthropod, Color Vision, Light Signal Transduction
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