Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Min, Sang-Won, Cho, Seo-Hyun, Zhou, Yungui, Schroeder, Sebastian, Haroutunian, Vahram, Seeley, William W., Huang, Eric J., Shen, Yong +6 more·2010·Neuron
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- Additional file 4 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic modelSanjib K Guha, Fischer, Sarah, Johnson, Gail V. W., Nehrke, Keith · 2020 · Figshare
- Additional file 1 of Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injuryParra Bravo, Celeste, Karen Krukowski, Barker, Sarah, Chao Wang, Li, Yaqiao, Fan, Li, Edwin Vázquez‐Rosa, Shin, Min-Kyoo, Man Ying Wong, McCullough, Louise D. et al. · 2024 · Figshare
- Additional file 1 of Tauopathy-associated tau modifications selectively impact neurodegeneration and mitophagy in a novel C. elegans single-copy transgenic modelSanjib K Guha, Fischer, Sarah, Johnson, Gail V. W., Keith W. Nehrke · 2020 · Figshare
- Additional file 4 of Anti-acetylated-tau immunotherapy is neuroprotective in tauopathy and brain injuryParra Bravo, Celeste, Karen Krukowski, Barker, Sarah, Wang, Chao, Li, Yaqiao, Fan, Li, Edwin Vázquez‐Rosa, Shin, Min-Kyoo, Man Ying Wong, McCullough, Louise D. et al. · 2024 · Figshare
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- BindingDB Entry 50033508: After the grape rush: sirtuins as epigenetic drug targets in neurodegenerative disorders.BindingDB · 2012 · UC San Diego
- BindingDB Entry 7461: Histone deacetylase 6 structure and molecular basis of catalysis and inhibitionBindingDB · 2016 · UC San Diego
- BindingDB Entry 50045373: Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.BindingDB · 2016 · UC San Diego
- BindingDB Entry 50016393: Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance.BindingDB · 2023 · UC San Diego
- BindingDB Entry 50042999: Progress and developments in tau aggregation inhibitors for Alzheimer disease.BindingDB · 2014 · UC San Diego
- BindingDB Entry 50003067: Design, synthesis, and biological evaluation of histone deacetylase inhibitors possessing glutathione peroxidase-like and antioxidant activities against Alzheimer's disease.BindingDB · 2020 · UC San Diego
- BindingDB Entry 50021669: Small molecules targeting molecular chaperones for tau regulation: Achievements and challenges.BindingDB · 2025 · UC San Diego
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