Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
Min, Sang-Won, Cho, Seo-Hyun, Zhou, Yungui, Schroeder, Sebastian, Haroutunian, Vahram, Seeley, William W., Huang, Eric J., Shen, Yong +6 more·2010·Neuron
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- Mitochondrial Acetylation and Genetic Models of Parkinson's DiseaseGeorg W. J. Auburger, Suzana Gispert, Marina Jendrach · 2014 · Progress in molecular biology and translational science
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- NAD-biosynthetic enzyme NMNAT1 reduces early behavioral impairment in the htau mouse model of tauopathyFrancesca Rossi, Philippine C. Geiszler, Weina Meng, Matthew R. Barron, Malcolm J. W. Prior, Anna Herd-Smith, Andrea Loreto, Maria Yanez Lopez, Henryk Faas, Marie‐Christine Pardon et al. · 2017 · Behavioural Brain Research
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- Identification of retinoblastoma binding protein 7 (Rbbp7) as a mediator against tau acetylation and subsequent neuronal loss in Alzheimer’s disease and related tauopathiesNikhil Dave, Austin S. Vural, Ignazio Stefano Piras, Wendy Winslow, Likith Surendra, Joanna K. Winstone, Thomas G. Beach, Matthew J. Huentelman, Ramón Velázquez · 2021 · Acta Neuropathologica
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- Epigenomics of Alzheimer's DiseaseRamón Cacabelos, Clara Torrellas, Francisco Javier Lopez-Munoz · 2014 · Journal of Experimental & Clinical Medicine
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- Altered Proteostasis in Neurodegenerative TauopathiesKaterina Papanikolopoulou, Efthimios M. C. Skoulakis · 2020 · Advances in experimental medicine and biology
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