The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly
Open accessAbstract
Research in the fruit fly Drosophila melanogaster has lead to insights in neural development, axon guidance, ion channel function, synaptic transmission, learning and memory, diurnal rythmicity, and neural disease that have had broad implications for neuroscience. Drosophila is currently the eukaryotic model organism that permits the most sophisticated in vivo manipulations to address the function of neurons and neuronally expressed genes. Here, we summarize many of the techniques that help assess the role of specific neurons by labeling, removing, or altering their activity. We also survey genetic manipulations to identify and characterize neural genes by mutation, over-expression, and protein labeling. Here, we attempt to acquaint the reader with available options and contexts to apply these methods.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system
Livet, J., Weissman, T. A., Kang, H., Draft, R. W., Lu, J., Bennis, R. A., Sanes, J. R., & Lichtman, J. W. (2007) · Nature · doi:10.1038/nature06293 · Cited by 1,876
Sweeney, S. T., Broadie, K., Keane, J., Niemann, H., & O'Kane, C. J. (1995) · Neuron · doi:10.1016/0896-6273(95)90290-2 · Cited by 938
Targeted Chromosomal Cleavage and Mutagenesis in Drosophila Using Zinc-Finger Nucleases
Bibikova, M., Golic, M., Golic, K. G., & Carroll, D. (2002) · Genetics · doi:10.1093/genetics/161.3.1169 · Cited by 860
The optic lobe of Drosophila melanogaster. I. A Golgi analysis of wild-type structure
Fischbach, K.-F., & Dittrich, A. P. M. (1989) · Cell and Tissue Research · doi:10.1007/bf00218858 · Cited by 709
The art and design of genetic screens: Drosophila melanogaster
St Johnston, D. (2002) · Nature Reviews Genetics · doi:10.1038/nrg751 · Cited by 644 · cited 2×
“7b. Transposon Mutagenesis Forward genetic screens based on transposon mutagenesis to identify new loci affecting neuronal features have so far been based on P elements (St Johnston, 2002) and piggyBac (Schuldiner et al., 2008).”
BackgroundMotor control in a Drosophila taste circuit
Gordon, M. D., & Scott, K. (2009) · Neuron · doi:10.1016/j.neuron.2008.12.033 · Cited by 531
Cellular Organization of the Neural Circuit that Drives Drosophila Courtship Behavior
Yu, J. Y., Kanai, M. I., Demir, E., Jefferis, G. S. X. E., & Dickson, B. J. (2010) · Current Biology · doi:10.1016/j.cub.2010.08.025 · Cited by 349
A dimorphic pheromone circuit in Drosophila from sensory input to descending output
Ruta, V., Datta, S. R., Vasconcelos, M. L., Freeland, J., Looger, L. L., & Axel, R. (2010) · Nature · doi:10.1038/nature09554 · Cited by 344
Waddell, S., Armstrong, J. D., Kitamoto, T., Kaiser, K., & Quinn, W. G. (2000) · Cell · doi:10.1016/s0092-8674(00)00183-5 · Cited by 332
Wired for Sex: The Neurobiology of Drosophila Mating Decisions
Dickson, B. J. (2008) · Science · doi:10.1126/science.1159276 · Cited by 314
Cited by
A GAL4-Driver Line Resource for Drosophila Neurobiology
Jenett, A., Rubin, G. M., Ngo, T.-T. B., Shepherd, D., Murphy, C., Dionne, H., Pfeiffer, B. D., Cavallaro, A., Hall, D., Jeter, J., et al. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.09.011 · Cited by 1,449
Self-citationA framework for studying emotions across species
Anderson, D. J., & Adolphs, R. (2014) · Cell · doi:10.1016/j.cell.2014.03.003 · Cited by 691
Nern, A., Pfeiffer, B. D., & Rubin, G. M. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1506763112 · Cited by 584
Inagaki, H. K., Jung, Y., Hoopfer, E. D., Wong, A. M., Mishra, N., Lin, J. Y., Tsien, R. Y., & Anderson, D. J. (2014) · Nature Methods · doi:10.1038/nmeth.2765 · Cited by 321
Consciousness in humans and non-human animals: recent advances and future directions
Boly, M., Seth, A. K., Wilke, M., Ingmundson, P., Baars, B., Laureys, S., Edelman, D. B., & Tsuchiya, N. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00625 · Cited by 291
Metadata
- Authors
- Venken, K. J. T., Simpson, J. H., & Bellen, H. J.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2011-10
- Volume
- 72
- Issue
- 2
- Pages
- 202-230
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2026386725
- Cited by
- 450
- References
- 21
- FWCI
- 14.17
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly. https://app.cochat.ai/papers/10.1016/j.neuron.2011.09.021
- The paper
- Venken, K. J. T., Simpson, J. H., & Bellen, H. J. (2011). Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly. Neuron. https://doi.org/10.1016/j.neuron.2011.09.021
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
