The amnesiac Gene Product Is Expressed in Two Neurons in the Drosophila Brain that Are Critical for Memory

Antibodies, a laboratory manual

(1989) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(89)90130-3 · Cited by 12,318 · see citing works

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Brand, A. H., & Perrimon, N. (1993) · Development · doi:10.1242/dev.118.2.401 · Cited by 9,510 · see citing works

Addiction, Dopamine, and the Molecular Mechanisms of Memory

Berke, J. D., & Hyman, S. E. (2000) · Neuron · doi:10.1016/s0896-6273(00)81056-9 · Cited by 1,167 · see citing works

Associative Odor Learning in Drosophila Abolished by Chemical Ablation of Mushroom Bodies

de Belle, J. S., & Heisenberg, M. (1994) · Science · doi:10.1126/science.8303280 · Cited by 797 · see citing works

Dynamin-like protein encoded by the Drosophila shibire gene associated with vesicular traffic

van der Bliek, A. M., & Meyerowrtz, E. M. (1991) · Nature · doi:10.1038/351411a0 · Cited by 770 · see citing works

Learning and memory in the honeybee

Hammer, M., & Menzel, R. (1995) · Journal of Neuroscience · doi:10.1523/jneurosci.15-03-01617.1995 · Cited by 726 · see citing works

Drosophila Mushroom Body Mutants are Deficient in Olfactory Learning

Heisenberg, M., Borst, A., Wagner, S., & Byers, D. (1985) · Journal of Neurogenetics · doi:10.3109/01677068509100140 · Cited by 697 · see citing works

An identified neuron mediates the unconditioned stimulus in associative olfactory learning in honeybees

Hammer, M. (1993) · Nature · doi:10.1038/366059a0 · Cited by 692 · see citing works

Conditioned Behavior in Drosophila melanogaster

Quinn, W. G., Harris, W. A., & Benzer, S. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.3.708 · Cited by 659 · see citing works

Chapter 24 Imaging Neuronal Subsets and Other Cell Types in Whole-Mount Drosophila Embryos and Larvae Using Antibody Probes

Patel, N. H. (1994) · Methods in cell biology · doi:10.1016/s0091-679x(08)60927-9 · Cited by 612 · see citing works

Localization of a Short-Term Memory in Drosophila

Zars, T. D., Fischer, M., Schulz, R. A., & Heisenberg, M. (2000) · Science · doi:10.1126/science.288.5466.672 · Cited by 600 · see citing works

Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis

Chen, M. S., Obar, R. A., Schroeder, C. C., Austin, T. W., Poodry, C. A., Wadsworth, S. C., & Vallee, R. B. (1991) · Nature · doi:10.1038/351583a0 · Cited by 558 · see citing works

D1/D5 receptor agonists induce a protein synthesis-dependent late potentiation in the CA1 region of the hippocampus.

Huang, Y.-Y., & Kandel, E. R. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.7.2446 · Cited by 544 · see citing works

Multiple Sites of Associative Odor Learning as Revealed by Local Brain Microinjections of Octopamine in HoneybeesPreprint

Hammer, M., & Menzel, R. (1998) · Learning & Memory · doi:10.1101/lm.5.1.146 · Cited by 530 · see citing works

Associative Learning Disrupted by Impaired G s Signaling in Drosophila Mushroom Bodies

Connolly, J. B., Roberts, I. J. H., Armstrong, J. D., Kaiser, K., Forte, M. A., Tully, T., & O’Kane, C. J. (1996) · Science · doi:10.1126/science.274.5295.2104 · Cited by 490 · see citing works

Tripartite Mushroom Body Architecture Revealed by Antigenic MarkersPreprint

Crittenden, J. R., Skoulakis, E. M. C., Han, K., Kalderon, D., & Davis, R. L. (1998) · Learning & Memory · doi:10.1101/lm.5.1.38 · Cited by 446 · see citing works

Disappearance and reformation of synaptic vesicle membrane upon transmitter release observed under reversible blockage of membrane retrieval

Koenig, J. H., & Ikeda, K. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-11-03844.1989 · Cited by 445 · see citing works

Development time and resistance to Bt crops

Liu, Y., Tabashnik, B. E., Dennehy, T. J., Patin, A. L., & Bartlett, A. C. (1999) · Nature · doi:10.1038/22919 · Cited by 441 · see citing works

Ethanol Intoxication in Drosophila: Genetic and Pharmacological Evidence for Regulation by the cAMP Signaling Pathway

Moore, M. S., DeZazzo, J., Luk, A. Y., Tully, T., Singh, C. M., & Heberlein, U. (1998) · Cell · doi:10.1016/s0092-8674(00)81205-2 · Cited by 430 · see citing works

Subdivision of the drosophila mushroom bodies by enhancer-trap expression patterns

Yang, M., Armstrong, J. D., Vilinsky, I., Strausfeld, N. J., & Kaiser, K. (1995) · Neuron · doi:10.1016/0896-6273(95)90063-2 · Cited by 348 · see citing works

The Organization of Extrinsic Neurons and Their Implications in the Functional Roles of the Mushroom Bodies inDrosophila melanogasterMeigenPreprint

Ito, K., Suzuki, K., Estes, P. S., Ramaswami, M., Yamamoto, D., & Strausfeld, N. J. (1998) · Learning & Memory · doi:10.1101/lm.5.1.52 · Cited by 337 · see citing works

Dopaminergic antagonists prevent long-term maintenance of posttetanic LTP in the CA1 region of rat hippocampal slices

Frey, U., Schroeder, H., & Matthies, H. (1990) · Brain Research · doi:10.1016/0006-8993(90)91578-5 · Cited by 333 · see citing works

Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila

Bainton, R. J., Tsai, L. T.-Y., Singh, C. M., Moore, M. S., Neckameyer, W. S., & Heberlein, U. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00336-5 · Cited by 316 · see citing works

Bee foraging in uncertain environments using predictive hebbian learning

Montague, P. R., Dayan, P., Person, C., & Sejnowski, T. J. (1995) · Nature · doi:10.1038/377725a0 · Cited by 311 · see citing works

Preferential expression in mushroom bodies of the catalytic subunit of protein kinase A and its role in learning and memory

Skoulakis, E. M. C., Kalderon, D., & Davis, R. L. (1993) · Neuron · doi:10.1016/0896-6273(93)90178-t · Cited by 293 · see citing works

Context generalization in Drosophila visual learning requires the mushroom bodies

Liu, L., Wolf, R., Ernst, R., & Heisenberg, M. (1999) · Nature · doi:10.1038/23456 · Cited by 281 · see citing works

Integrin-mediated short-term memory in Drosophila

Grotewiel, M. S., Beck, C., Wu, K. H., Zhu, X., & Davis, R. L. (1998) · Nature · doi:10.1038/35079 · Cited by 277 · see citing works

A Neuropeptide Gene Defined by the Drosophila Memory Mutant amnesiac

Feany, M. Β., & Quinn, W. G. (1995) · Science · doi:10.1126/science.7754370 · Cited by 269 · see citing works

Mushroom Body Ablation Impairs Short-Term Memory and Long-Term Memory of Courtship Conditioning in Drosophila melanogaster

McBride, S. M. J., Giuliani, G., Choi, C. H., Krause, P., Correale, D., Watson, K. K., Baker, G., & Siwicki, K. K. (1999) · Neuron · doi:10.1016/s0896-6273(00)81043-0 · Cited by 261 · see citing works

Two endogenous neuropeptides modulate the gill and siphon withdrawal reflex in Aplysia by presynaptic facilitation involving cAMP-dependent closure of a serotonin-sensitive potassium channel.

Abrams, T. W., Castellucci, V. F., Camardo, J. S., Kandel, E. R., & Lloyd, P. E. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.24.7956 · Cited by 254 · see citing works

The cyclic AMP phosphodiesterase encoded by the drosophila dunce gene is concentrated in the mushroom body neuropil

Nighorn, A. J., Healy, M. J., & Davis, R. L. (1991) · Neuron · doi:10.1016/0896-6273(91)90253-v · Cited by 251 · see citing works

The Drosophila memory mutant amnesiac

Quinn, W. G., Sziber, P. P., & Booker, R. (1979) · Nature · doi:10.1038/277212a0 · Cited by 243 · see citing works

Preferential expression of the drosophila rutabaga gene in mushroom bodies, neural centers for learning in insects

Han, P., Levin, L. R., Reed, R. R., & Davis, R. L. (1992) · Neuron · doi:10.1016/0896-6273(92)90026-a · Cited by 238 · see citing works

Ectopic G-protein expression in dopamine and serotonin neurons blocks cocaine sensitization in Drosophila melanogaster

Li, H., Chaney, S. C., Forte, M. A., & Hirsh, J. (2000) · Current Biology · doi:10.1016/s0960-9822(00)00340-7 · Cited by 235 · see citing works

Olfactory Learning Deficits in Mutants for leonardo, a Drosophila Gene Encoding a 14-3-3 Protein

Skoulakis, E. M. C., & Davis, R. L. (1996) · Neuron · doi:10.1016/s0896-6273(00)80224-x · Cited by 209 · see citing works

Identified serotonergic neurons LCB1 and RCB1 in the cerebral ganglia of Aplysia produce presynaptic facilitation of siphon sensory neurons

Mackey, S. L., Kandel, E., & Hawkins, R. (1989) · Journal of Neuroscience · doi:10.1523/jneurosci.09-12-04227.1989 · Cited by 193 · see citing works

Drosophila Mushroom Bodies Are Dispensable for Visual, Tactile, and Motor LearningPreprint

Wolf, R., Wittig, T., Liu, L., Wustmann, G., Eyding, D., & Heisenberg, M. (1998) · Learning & Memory · doi:10.1101/lm.5.1.166 · Cited by 156 · see citing works

Localization and gene expression of the receptor for pituitary adenylate cyclase-activating polypeptide in the rat brain

Shioda, S., Shuto, Y., Somogyvári-Vigh, A., Légrádi, G., Onda, H., Coy, D. H., Nakajo, S., & Arimura, A. (1997) · Neuroscience Research · doi:10.1016/s0168-0102(97)00065-5 · Cited by 147 · see citing works

Metamorphosis of the Mushroom Bodies; Large-Scale Rearrangements of the Neural Substrates for Associative Learning and Memory in DrosophilaPreprint

Armstrong, J. D., de Belle, J. S., Wang, Z., & Kaiser, K. (1998) · Learning & Memory · doi:10.1101/lm.5.1.102 · Cited by 144 · see citing works

Neurotransmitter transporters: fruitful targets for CNS drug discovery

Iversen, L. (2000) · Molecular Psychiatry · doi:10.1038/sj.mp.4000728 · Cited by 142 · see citing works

Neuropeptides, Adenylyl Cyclase, and Memory Storage

Kandel, E. R., & Abel, T. G. (1995) · Science · doi:10.1126/science.7754367 · Cited by 120 · see citing works

Type II cAMP-dependent Protein Kinase-deficientDrosophila Are Viable but Show Developmental, Circadian, and Drug Response Phenotypes

Park, S. K., Sedore, S. A., Cronmiller, C., & Hirsh, J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m002460200 · Cited by 109 · see citing works

Dopamine D1-deficient mutant mice do not express the late phase of hippocampal long-term potentiation

Matthies, H., Becker, A., Schröeder, H., Kraus, J., Höllt, V., & Krug, M. (1997) · Neuroreport · doi:10.1097/00001756-199711100-00023 · Cited by 106 · see citing works

Facing death in the fly: genetic analysis of apoptosis in Drosophila

McCall, K., & Steller, H. (1997) · Trends in Genetics · doi:10.1016/s0168-9525(97)01126-8 · Cited by 83 · see citing works

Interspecific comparison of a Drosophila gene encoding FMRFamide- related neuropeptides

Taghert, P., & Schneider, L. E. (1990) · Journal of Neuroscience · doi:10.1523/jneurosci.10-06-01929.1990 · Cited by 76 · see citing works

Peptide Cotransmitter Release from Motorneuron B16 inAplysia californica: Costorage, Corelease, and Functional Implications

Vilim, F. S., Cropper, E. C., Price, D. A., Kupfermann, I., & Weiss, K. R. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-05-02036.2000 · Cited by 75 · see citing works

Developmental Expression of anamn+Transgene Rescues the Mutant Memory Defect ofamnesiacAdults

DeZazzo, J. D., Xia, S., Christensen, J., Velinzon, K., & Tully, T. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-20-08740.1999 · Cited by 74 · see citing works

Presynaptic localization of the PACAP-typeI-receptor in hippocampal and cerebellar mossy fibres

Otto, C., Zuschratter, W., Gass, P., & Schütz, G. (1999) · Molecular Brain Research · doi:10.1016/s0169-328x(99)00010-8 · Cited by 45 · see citing works

Serotonin and the Small Cardioactive Peptides Differentially Modulate Two Motor Neurons That Innervate the Same Muscle Fibers inAplysia

Fox, L. E., & Lloyd, P. E. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-16-06064.1997 · Cited by 39 · see citing works

Myomodulin application increases cAMP and activates cAMP-dependent protein kinase in the accessory radual closer muscle of Aplysia

Hooper, S. L., PROBST, W. C., Cropper, E. C., Kupfermann, I., & Weiss, K. R. (1994) · Neuroscience Letters · doi:10.1016/0304-3940(94)90960-1 · Cited by 15 · see citing works

Abnormal mushroom body plasticity in the Drosophila memory mutant amnesiac

Hitier, R., Heisenberg, M., & Préat, T. (1998) · Neuroreport · doi:10.1097/00001756-199808240-00006 · Cited by 10 · see citing works

Role of cAMP in the Short-Term Modulation of a Neuromuscular System inAplysia

Fox, L. E., & Lloyd, P. E. (2000) · Journal of Neurophysiology · doi:10.1152/jn.2000.83.3.1567 · Cited by 9 · see citing works

Drosophila Mushroom Bodies Are Dispensable for Visual, Tactile, and Motor Learning

Wolf, R., Wittig, T., Liu, L., Wustmann, G., Eyding, D., & Heisenberg, M. (1998) · Europe PMC (PubMed Central) · Cited by 8 · see citing works

Metamorphosis of the mushroom bodies; large scale rearrangements of the neural substrates for associative learning and memory in Drosophila.

Armstrong, J., de Belle, J., Wang, Z., & Kaiser, K. (1998) · MPG.PuRe (Max Planck Society) · Cited by 4 · see citing works

Mushroom body memoir: from maps to models

Heisenberg, M. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1074 · Cited by 1,286 · see citing works

The neuronal architecture of the mushroom body provides a logic for associative learning

Aso, Y., Hattori, D., Yu, Y., Johnston, R. M., Iyer, N. A., Ngo, T.-T., Dionne, H., Abbott, L., Axel, R., Tanimoto, H., et al. (2014) · eLife · doi:10.7554/elife.04577 · Cited by 1,051 · see citing works

Dopamine and Octopamine Differentiate between Aversive and Appetitive Olfactory Memories in <i>Drosophila</i>

Schwaerzel, M., Monastirioti, M., Scholz, H., Friggi-Grelin, F., Birman, S., & Heisenberg, M. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-33-10495.2003 · Cited by 871 · see citing works

Conditional modification of behavior in Drosophila by targeted expression of a temperature‐sensitive shibire allele in defined neurons

Kitamoto, T. (2001) · Journal of Neurobiology · doi:10.1002/neu.1018 · Cited by 868 · see citing works

Genetic Dissection of Neural Circuits

Luo, L., Callaway, E. M., & Svoboda, K. (2008) · Neuron · doi:10.1016/j.neuron.2008.01.002 · Cited by 754 · see citing works

Molecular mechanisms of memory acquisition, consolidation and retrieval

Abel, T. G., & Lattal, K. M. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00194-x · Cited by 689 · see citing works

Layered reward signalling through octopamine and dopamine in Drosophila

Burke, C. J., Huetteroth, W., Owald, D., Perisse, E., Krashes, M. J., Das, G., Gohl, D., Silies, M., Certel, S., & Waddell, S. (2012) · Nature · doi:10.1038/nature11614 · Cited by 614 · see citing works

OLFACTORY MEMORY FORMATION INDROSOPHILA: From Molecular to Systems Neuroscience

Davis, R. L. (2005) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.28.061604.135651 · Cited by 543 · see citing works

Drosophila neuropeptides in regulation of physiology and behavior

Nässel, D. R., & Winther, Å. M. E. (2010) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2010.04.010 · Cited by 495 · see citing works

Neuropeptides in the nervous system of Drosophila and other insects: multiple roles as neuromodulators and neurohormones

Nässel, D. R. (2002) · Progress in Neurobiology · doi:10.1016/s0301-0082(02)00057-6 · Cited by 482 · see citing works

Neuronal assemblies of the <i>Drosophila</i> mushroom body

Tanaka, N. K., Tanimoto, H., & Ito, K. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21692 · Cited by 470 · see citing works

Drosophila: Genetics meets behaviour

Sokolowski, M. B. (2001) · Nature Reviews Genetics · doi:10.1038/35098592 · Cited by 474 · see citing works

The Role of Drosophila Mushroom Body Signaling in Olfactory Memory

McGuire, S. E., Le, P. T., & Davis, R. L. (2001) · Science · doi:10.1126/science.1062622 · Cited by 457 · see citing works

Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory

Dubnau, J., Grady, L., Kitamoto, T., & Tully, T. (2001) · Nature · doi:10.1038/35078077 · Cited by 455 · see citing works

Genetic Manipulation of Genes and Cells in the Nervous System of the Fruit Fly

Venken, K. J. T., Simpson, J. H., & Bellen, H. J. (2011) · Neuron · doi:10.1016/j.neuron.2011.09.021 · Cited by 442 · see citing works

Sequential Use of Mushroom Body Neuron Subsets during Drosophila Odor Memory Processing

Krashes, M. J., Keene, A. C., Leung, B., Armstrong, J. D., & Waddell, S. (2007) · Neuron · doi:10.1016/j.neuron.2006.11.021 · Cited by 422 · see citing works

P{Switch}, a system for spatial and temporal control of gene expression in Drosophila melanogaster

Roman, G., Endo, K., Zong, L., & Davis, R. L. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.221303998 · Cited by 406 · see citing works

Using translational enhancers to increase transgene expression in Drosophila

Pfeiffer, B. D., Truman, J. W., & Rubin, G. M. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1204520109 · Cited by 397 · see citing works

The connectome of the adult Drosophila mushroom body provides insights into function

Li, F., Lindsey, J. W., Marin, E. C., Otto, N., Dreher, M., Dempsey, G., Stark, I., Bates, A. S., Pleijzier, M. W., Schlegel, P., et al. (2020) · eLife · doi:10.7554/elife.62576 · Cited by 403 · see citing works

The Mushroom Body of Adult Drosophila Characterized by GAL4 Drivers

Aso, Y., Grübel, K., Busch, S., Friedrich, A. B., Siwanowicz, I., & Tanimoto, H. (2009) · Journal of Neurogenetics · doi:10.1080/01677060802471718 · Cited by 381 · see citing works

Drosophila olfactory memory: single genes to complex neural circuits

Keene, A. C., & Waddell, S. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2098 · Cited by 384 · see citing works

A connectome of a learning and memory center in the adult Drosophila brain

Takemura, S.-Y., Aso, Y., Hige, T., Wong, A., Lu, Z., Xu, C. S., Rivlin, P. K., Hess, H., Zhao, T., Parag, T., et al. (2017) · eLife · doi:10.7554/elife.26975 · Cited by 367 · see citing works

Deconstructing Memory in Drosophila

Margulies, C. E., Tully, T., & Dubnau, J. (2005) · Current Biology · doi:10.1016/j.cub.2005.08.024 · Cited by 336 · see citing works

STRUCTURE OF THE MUSHROOM BODIES OF THE INSECT BRAIN

Fahrbach, S. E. (2005) · Annual Review of Entomology · doi:10.1146/annurev.ento.51.110104.150954 · Cited by 318 · see citing works

A genetically encoded sensor for measuring serotonin dynamics

Wan, J., Peng, W., Li, X., Qian, T., Song, K., Zeng, J., Deng, F., Hao, S., Feng, J., Zhang, P., et al. (2021) · Nature Neuroscience · doi:10.1038/s41593-021-00823-7 · Cited by 293 · see citing works

Rapid Consolidation to aradishand Protein Synthesis-Dependent Long-Term Memory after Single-Session Appetitive Olfactory Conditioning inDrosophila

Krashes, M. J., & Waddell, S. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.5333-07.2008 · Cited by 297 · see citing works

Dopamine Is Required for Learning and Forgetting in Drosophila

Berry, J. A., Cervantes-Sandoval, I., Nicholas, E. P., & Davis, R. L. (2012) · Neuron · doi:10.1016/j.neuron.2012.04.007 · Cited by 296 · see citing works

Traces of Drosophila Memory

Davis, R. L. (2011) · Neuron · doi:10.1016/j.neuron.2011.03.012 · Cited by 290 · see citing works

Do the right thing: neural network mechanisms of memory formation, expression and update in Drosophila

Cognigni, P., Felsenberg, J., & Waddell, S. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.12.002 · Cited by 281 · see citing works

Neuropeptides as Regulators of Behavior in Insects

Schoofs, L., LOOF, A. D., & Hiel, M. B. V. (2016) · Annual Review of Entomology · doi:10.1146/annurev-ento-031616-035500 · Cited by 269 · see citing works

Ras Activity in the Drosophila Prothoracic Gland Regulates Body Size and Developmental Rate via Ecdysone Release

Caldwell, P. E., Walkiewicz, M. A., & Stern, M. (2005) · Current Biology · doi:10.1016/j.cub.2005.09.011 · Cited by 268 · see citing works

Drosophila α/β Mushroom Body Neurons Form a Branch-Specific, Long-Term Cellular Memory Trace after Spaced Olfactory Conditioning

Yu, D., Akalal, D.-B. G., & Davis, R. L. (2006) · Neuron · doi:10.1016/j.neuron.2006.10.030 · Cited by 266 · see citing works

Overexpression of type-1 adenylyl cyclase in mouse forebrain enhances recognition memory and LTP

Wang, H., Ferguson, G. D., Pineda, V. V., Cundiff, P. E., & Storm, D. R. (2004) · Nature Neuroscience · doi:10.1038/nn1248 · Cited by 244 · see citing works

Neurotransmitter classification from electron microscopy images at synaptic sites in Drosophila melanogaster

Eckstein, N., Bates, A. S., Champion, A., Du, M., Yin, Y., Schlegel, P., Lu, A. K.-Y., Rymer, T., Finley-May, S., Paterson, T., et al. (2024) · Cell · doi:10.1016/j.cell.2024.03.016 · Cited by 233 · see citing works

NMDA Receptors Mediate Olfactory Learning and Memory in Drosophila

Xia, S., Miyashita, T., Fu, T., Lin, W., Wu, C., Pyzocha, L., Lin, I.-R., Saitoe, M., Tully, T., & Chiang, A. (2005) · Current Biology · doi:10.1016/j.cub.2005.02.059 · Cited by 226 · see citing works

A Map of Olfactory Representation in the Drosophila Mushroom Body

Lin, H., Lai, J. S.-Y., Chin, A., Chen, Y., & Chiang, A. (2007) · Cell · doi:10.1016/j.cell.2007.03.006 · Cited by 224 · see citing works

Altered Representation of the Spatial Code for Odors after Olfactory Classical Conditioning

Yu, D., Ponomarev, A. L., & Davis, R. L. (2004) · Neuron · doi:10.1016/s0896-6273(04)00217-x · Cited by 222 · see citing works

Thirty years of olfactory learning and memory research in Drosophila melanogaster

McGuire, S. E., Deshazer, M., & Davis, R. L. (2005) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2005.09.003 · Cited by 220 · see citing works

Dynamics of Learning-Related cAMP Signaling and Stimulus Integration in the Drosophila Olfactory Pathway

Tomchik, S. M., & Davis, R. L. (2009) · Neuron · doi:10.1016/j.neuron.2009.09.029 · Cited by 217 · see citing works

Invertebrate models of drug abuse

Wolf, F. W., & Heberlein, U. (2002) · Journal of Neurobiology · doi:10.1002/neu.10166 · Cited by 214 · see citing works

Chapter 3 Neurogenetics of Courtship and Mating in Drosophila

Villella, A., & Hall, J. C. (2008) · Advances in genetics · doi:10.1016/s0065-2660(08)00603-2 · Cited by 205 · see citing works

Neuropeptides in interneurons of the insect brain

Nässel, D. R., & Homberg, U. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0210-8 · Cited by 201 · see citing works

Activation of Trk Neurotrophin Receptor Signaling by Pituitary Adenylate Cyclase-activating Polypeptides

Lee, F. S., Rajagopal, R., Kim, A. H., Chang, P. C.-Y., & Chao, M. V. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m107421200 · Cited by 200 · see citing works

TrpA1 Regulates Thermal Nociception in Drosophila

Neely, G. G., Keene, A. C., Duchek, P., Chang, E. C., Wang, Q., Aksoy, Y. A., Rosenzweig, M. R., Costigan, M., Woolf, C. J., Garrity, P., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0024343 · Cited by 191 · see citing works

Drosophilaas a new model organism for the neurobiology of aggression?

Baier, A., Wittek, B., & Brembs, B. (2002) · Journal of Experimental Biology · doi:10.1242/jeb.205.9.1233 · Cited by 187 · see citing works

A single pair of neurons links sleep to memory consolidation in Drosophila melanogaster

Haynes, P. R., Christmann, B. L., & Griffith, L. C. (2015) · eLife · doi:10.7554/elife.03868 · Cited by 186 · see citing works

Defining the role of Drosophila lateral neurons in the control of circadian rhythms in motor activity and eclosion by targeted genetic ablation and PERIOD protein overexpression

Blanchardon, E., Grima, B., Klarsfeld, A., Chélot, E., Hardin, P. E., Préat, T., & Rouyer, F. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2000.01450.x · Cited by 179 · see citing works

Flies, Genes, and Learning

Waddell, S., & Quinn, W. G. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.1283 · Cited by 184 · see citing works

Extinction Antagonizes Olfactory Memory at the Subcellular Level

Schwärzel, M., Heisenberg, M., & Zars, T. D. (2002) · Neuron · doi:10.1016/s0896-6273(02)00832-2 · Cited by 182 · see citing works

An engram found? Evaluating the evidence from fruit flies

Gerber, B., Tanimoto, H., & Heisenberg, M. (2004) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2004.10.014 · Cited by 181 · see citing works

HEN-1, a Secretory Protein with an LDL Receptor Motif, Regulates Sensory Integration and Learning in Caenorhabditis elegans

Ishihara, T., Iino, Y., Mohri, A., Mori, I., Gengyo‐Ando, K., Mitani, S., & Katsura, I. (2002) · Cell · doi:10.1016/s0092-8674(02)00748-1 · Cited by 181 · see citing works

Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body

Wu, C., Xia, S., Fu, T., Wang, H., Chen, Y.-H., Leong, D. J., Chiang, A., & Tully, T. (2007) · Nature Neuroscience · doi:10.1038/nn2005 · Cited by 175 · see citing works

Contribution of photoreceptor subtypes to spectral wavelength preference in Drosophila

Yamaguchi, S., Desplan, C., & Heisenberg, M. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0809398107 · Cited by 171 · see citing works

Aging Specifically Impairs amnesiac-Dependent Memory in Drosophila

Tamura, T., Chiang, A., Ito, N., Liu, H., Horiuchi, J., Tully, T., & Saitoe, M. (2003) · Neuron · doi:10.1016/s0896-6273(03)00732-3 · Cited by 171 · see citing works

Drosophila DPM Neurons Form a Delayed and Branch-Specific Memory Trace after Olfactory Classical Conditioning

Yu, D., Keene, A. C., Srivatsan, A., Waddell, S., & Davis, R. L. (2005) · Cell · doi:10.1016/j.cell.2005.09.037 · Cited by 167 · see citing works

Functional neuroanatomy of Drosophila olfactory memory formationPreprint

Guven-Ozkan, T., & Davis, R. L. (2014) · Learning & Memory · doi:10.1101/lm.034363.114 · Cited by 166 · see citing works

Learning and Memory in Drosophila: Behavior, Genetics, and Neural Systems

Kahsai, L., & Zars, T. D. (2011) · International review of neurobiology · doi:10.1016/b978-0-12-387003-2.00006-9 · Cited by 159 · see citing works

The mushroom bodies of Drosophila melanogaster: An immunocytological and golgi study of Kenyon cell organization in the calyces and lobes

Strausfeld, N. J., Sinakevitch, I. G., & Vilinsky, I. (2003) · Microscopy Research and Technique · doi:10.1002/jemt.10368 · Cited by 155 · see citing works

Pharmacogenetic rescue in time and space of the rutabaga memory impairment by using Gene-Switch

Mao, Z., Roman, G., Zong, L., & Davis, R. L. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0306128101 · Cited by 153 · see citing works

Retrograde Signaling by Syt 4 Induces Presynaptic Release and Synapse-Specific Growth

Yoshihara, M., Adolfsen, B., Galle, K. T., & Littleton, J. T. (2005) · Science · doi:10.1126/science.1117541 · Cited by 153 · see citing works

Neuronal wiring diagram of an adult brain

Dorkenwald, S., Matsliah, A., Sterling, A. R., Schlegel, P., Yu, S.-C., McKellar, C. E., Lin, A., Costa, M., Eichler, K., Yin, Y., et al. (2023) · doi:10.1101/2023.06.27.546656 · Cited by 149 · see citing works

Diverse Odor-Conditioned Memories Require Uniquely Timed Dorsal Paired Medial Neuron Output

Keene, A. C., Stratmann, M., Keller, A., Perrat, P. N., Vosshall, L. B., & Waddell, S. (2004) · Neuron · doi:10.1016/j.neuron.2004.10.006 · Cited by 149 · see citing works

Serotonin–mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila

Lee, P.-T., Lin, H.-W., Chang, Y. A., Fu, T., Dubnau, J., Hirsh, J., Lee, T., & Chiang, A. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1019483108 · Cited by 147 · see citing works

Evolution of insect mushroom bodies: old clues, new insights

Farris, S. M. (2005) · Arthropod Structure & Development · doi:10.1016/j.asd.2005.01.008 · Cited by 146 · see citing works

Functional architecture of reward learning in mushroom body extrinsic neurons of larval Drosophila

Saumweber, T., Rohwedder, A., Schleyer, M. H., Eichler, K., Chen, Y., Aso, Y., Cardona, A., Eschbach, C., Kobler, O., Voigt, A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03130-1 · Cited by 154 · see citing works

Roles for Drosophila mushroom body neurons in olfactory learning and memoryPreprint

Akalal, D.-B. G., Wilson, C. F., Zong, L., Tanaka, N. K., Ito, K., & Davis, R. L. (2006) · Learning & Memory · doi:10.1101/lm.221206 · Cited by 138 · see citing works

Drosophila Dorsal Paired Medial Neurons Provide a General Mechanism for Memory Consolidation

Keene, A. C., Krashes, M. J., Leung, B., Bernard, J. A., & Waddell, S. (2006) · Current Biology · doi:10.1016/j.cub.2006.06.022 · Cited by 137 · see citing works

A Pair of Inhibitory Neurons Are Required to Sustain Labile Memory in the Drosophila Mushroom Body

Pitman, J. L., Huetteroth, W., Burke, C. J., Krashes, M. J., Lai, S.-L., Lee, T., & Waddell, S. (2011) · Current Biology · doi:10.1016/j.cub.2011.03.069 · Cited by 137 · see citing works

Molecular biology and anatomy of Drosophila olfactory associative learning

Roman, G., & Davis, R. L. (2001) · BioEssays · doi:10.1002/bies.1083 · Cited by 134 · see citing works

Pokes, sunburn, and hot sauce: Drosophila as an emerging model for the biology of nociception

Im, S. H., & Galko, M. J. (2011) · Developmental Dynamics · doi:10.1002/dvdy.22737 · Cited by 135 · see citing works

Network statistics of the whole-brain connectome of Drosophila

Lin, A., Yang, R., Dorkenwald, S., Matsliah, A., Sterling, A. R., Schlegel, P., Yu, S.-C., McKellar, C. E., Costa, M., Eichler, K., et al. (2024) · Nature · doi:10.1038/s41586-024-07968-y · Cited by 147 · see citing works

Drosophila fasciclinII Is Required for the Formation of Odor Memories and for Normal Sensitivity to Alcohol

Cheng, Y., Endo, K., Wu, K., Rodan, A. R., Heberlein, U., & Davis, R. L. (2001) · Cell · doi:10.1016/s0092-8674(01)00386-5 · Cited by 129 · see citing works

Multimodal sensory integration in insects—towards insect brain control architectures

Wessnitzer, J., & Webb, B. H. (2006) · Bioinspiration & Biomimetics · doi:10.1088/1748-3182/1/3/001 · Cited by 127 · see citing works

Multiple Amidated Neuropeptides Are Required for Normal Circadian Locomotor Rhythms inDrosophila

Taghert, P. H., Hewes, R. S., Park, J. H., O’Brien, M. A., Han, M., & Peck, M. E. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-17-06673.2001 · Cited by 126 · see citing works

Imaging of an Early Memory Trace in theDrosophilaMushroom Body

Wang, Y., Mamiya, A., Chiang, A., & Zhong, Y. (2008) · Journal of Neuroscience · doi:10.1523/jneurosci.2958-07.2008 · Cited by 124 · see citing works

Olfaction and olfactory learning in Drosophila: recent progress

Fiala, A. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.11.009 · Cited by 124 · see citing works

Centrophobism/thigmotaxis, a new role for the mushroom bodies inDrosophila

Besson, M., & Martin, J.-R. (2004) · Journal of Neurobiology · doi:10.1002/neu.20111 · Cited by 121 · see citing works

An Octopamine-Mushroom Body Circuit Modulates the Formation of Anesthesia-Resistant Memory in Drosophila

Wu, C., Shih, M.-F. M., Lee, P.-T., & Chiang, A. (2013) · Current Biology · doi:10.1016/j.cub.2013.09.056 · Cited by 118 · see citing works

Intrinsic neurons of <i>Drosophila</i> mushroom bodies express short neuropeptide F: Relations to extrinsic neurons expressing different neurotransmitters

Johard, H. A. D., Enell, L. E., Gustafsson, E., Trifilieff, P., Veenstra, J. A., & Nässel, D. R. (2008) · Journal of Comparative Neurology · doi:10.1002/cne.21636 · Cited by 120 · see citing works

Conditional disruption of synaptic transmission induces male–male courtship behavior in Drosophila

Kitamoto, T. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202489099 · Cited by 120 · see citing works

Neural substrates of memory: From synapse to system

Dubnau, J., Chiang, A., & Tully, T. (2002) · Journal of Neurobiology · doi:10.1002/neu.10170 · Cited by 116 · see citing works

Neurotransmitter Classification from Electron Microscopy Images at Synaptic Sites in Drosophila Melanogaster

Eckstein, N., Bates, A. S., Champion, A., Du, M., Yin, Y., Schlegel, P., Lu, A. K.-Y., Rymer, T., Finley-May, S., Paterson, T., et al. (2020) · doi:10.1101/2020.06.12.148775 · Cited by 115 · see citing works

Heterotypic Gap Junctions between Two Neurons in the Drosophila Brain Are Critical for Memory

Wu, C., Shih, M.-F. M., Lai, J. S.-Y., Yang, H.-T., Turner, G. C., Chen, L., & Chiang, A. (2011) · Current Biology · doi:10.1016/j.cub.2011.02.041 · Cited by 112 · see citing works

Smelling, Tasting, Learning: Drosophila as a Study Case

Gerber, B., Stocker, R. F., Tanimura, T., & Thum, A. S. (2009) · Results and problems in cell differentiation · doi:10.1007/400_2008_9 · Cited by 112 · see citing works

Hmgcr in the Corpus Allatum Controls Sexual Dimorphism of Locomotor Activity and Body Size via the Insulin Pathway in Drosophila

Belgacem, Y. H., & Martin, J. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000187 · Cited by 110 · see citing works

Distinctive Neuronal Networks and Biochemical Pathways for Appetitive and Aversive Memory inDrosophilaLarvae

Honjo, K., & Furukubo-Tokunaga, K. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.1315-08.2009 · Cited by 106 · see citing works

Development of neuronal connectivity in Drosophila antennal lobes and mushroom bodies

Jefferis, G. S. X. E., Marin, E. C., Watts, R. J., & Luo, L. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00293-3 · Cited by 106 · see citing works

Sequential Learning of Pheromonal Cues Modulates Memory Consolidation in Trainer-Specific Associative Courtship Conditioning

Ejima, A., Smith, B. P. C., Lucas, C., Levine, J. D., & Griffith, L. C. (2005) · Current Biology · doi:10.1016/j.cub.2005.01.035 · Cited by 105 · see citing works

The Receptor Tyrosine Kinase Alk Controls Neurofibromin Functions in Drosophila Growth and Learning

Gouzi, J. Y., Moressis, A., Walker, J. A., Apostolopoulou, A. A., Palmer, R. H., Bernards, A., & Skoulakis, E. M. C. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002281 · Cited by 103 · see citing works

Drosophila Larvae Establish Appetitive Olfactory Memories via Mushroom Body Neurons of Embryonic Origin

Pauls, D., Selcho, M., Gendre, N., Stocker, R. F., & Thum, A. S. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.1281-10.2010 · Cited by 103 · see citing works

Chapter 3 Mapping and Manipulating Neural Circuits in the Fly Brain

Simpson, J. H. (2009) · Advances in genetics · doi:10.1016/s0065-2660(09)65003-3 · Cited by 103 · see citing works

Operant conditioning in invertebrates

Brembs, B. (2003) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2003.10.002 · Cited by 102 · see citing works

Drosophila Neuropeptide Signaling

Taghert, P. H., & Veenstra, J. A. (2003) · Advances in genetics · doi:10.1016/s0065-2660(03)01001-0 · Cited by 97 · see citing works

System-Like Consolidation of Olfactory Memories in Drosophila

Cervantes-Sandoval, I., Martín‐Peña, A., Berry, J. A., & Davis, R. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0451-13.2013 · Cited by 93 · see citing works

Of Flies and Man:Drosophilaas a Model for Human Complex Traits

Mackay, T. F. C., & Anholt, R. R. H. (2006) · Annual Review of Genomics and Human Genetics · doi:10.1146/annurev.genom.7.080505.115758 · Cited by 94 · see citing works

What can we teach Drosophila? What can they teach us?

Waddell, S., & Quinn, W. G. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(01)02526-4 · Cited by 92 · see citing works

Presynapses in Kenyon Cell Dendrites in the Mushroom Body Calyx of Drosophila

Christiansen, F., Zube, C., Andlauer, T. F. M., Wichmann, C., Fouquet, W., Owald, D., Mertel, S., Leiss, F., Tavosanis, G., Luna, A. J. F., et al. (2011) · Journal of Neuroscience · doi:10.1523/jneurosci.6542-10.2011 · Cited by 90 · see citing works

Sleep in Insects

Helfrich‐Förster, C. (2017) · Annual Review of Entomology · doi:10.1146/annurev-ento-020117-043201 · Cited by 87 · see citing works

Functional Dissection of Neuroanatomical Loci Regulating Ethanol Sensitivity inDrosophila

Rodan, A. R., Kiger, J. A., & Heberlein, U. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-21-09490.2002 · Cited by 89 · see citing works

The Serotonergic Central Nervous System of the Drosophila Larva: Anatomy and Behavioral Function

Huser, A., Rohwedder, A., Apostolopoulou, A. A., Widmann, A., Pfitzenmaier, J. E., Maiolo, E. M., Selcho, M., Pauls, D., von Essen, A. M. H. J., Gupta, T., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0047518 · Cited by 86 · see citing works

Amnesiac Is Required in the Adult Mushroom Body for Memory Formation

Turrel, O., Goguel, V., & Préat, T. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.0876-18.2018 · Cited by 24 · see citing works

Flying down memory lane

Wood, H. B. (2001) · Nature reviews. Neuroscience · doi:10.1038/35049026

Functional anatomy: From molecule to memory

Dubnau, J., & Tully, T. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00115-4 · Cited by 44 · see citing works

Developmental Expression of anamn+Transgene Rescues the Mutant Memory Defect ofamnesiacAdults

DeZazzo, J. D., Xia, S., Christensen, J., Velinzon, K., & Tully, T. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-20-08740.1999 · Cited by 74 · see citing works

Mushroom Bodies, Ca2+ Oscillations, and the Memory Gene amnesiac

Davis, R. L. (2001) · Neuron · doi:10.1016/s0896-6273(01)00329-4 · Cited by 32 · see citing works