FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels

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2. Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease
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3. Ca2+- and Voltage-Activated K+ (BK) Channels in the Nervous System: One Gene, a Myriad of Physiological Functions
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4. Single-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRP
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5. Cereblon Maintains Synaptic and Cognitive Function by Regulating BK Channel
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6. Abnormal Sleep Architecture and Hippocampal Circuit Dysfunction in a Mouse Model of Fragile X Syndrome
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7. mGluR5 Negative Modulators for Fragile X: Treatment Resistance and Persistence
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8. Stimulation of Slack K+ Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex
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9. The Fragile X Protein and Genome Function
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10. Past and Future of Analog-Digital Modulation of Synaptic Transmission
    Mickaël Zbili, Dominique Debanne · 2019 · Frontiers in Cellular Neuroscience
11. Partial FMRP expression is sufficient to normalize neuronal hyperactivity in Fragile X neurons
    John D. Graef, Hao Wu, Carrie Ng, Chicheng Sun, Vivian Villegas, Deena Qadir, Kimberly Jesseman, Stephen T. Warren, Rudolf Jaenisch, Angela M. Cacace et al. · 2019 · European Journal of Neuroscience
12. Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
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13. Astroglial Kir4.1 potassium channel deficit drives neuronal hyperexcitability and behavioral defects in fragile X syndrome mouse model
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14. GABABreceptor‐mediated feed‐forward circuit dysfunction in the mouse model of fragile X syndrome
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15. Potential Involvement of Impaired BKCa Channel Function in Sensory Defensiveness and Some Behavioral Disturbances Induced by Unfamiliar Environment in a Mouse Model of Fragile X Syndrome
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16. Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity
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17. The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic Paraplegias
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18. FMRP(1–297)-tat restores ion channel and synaptic function in a model of Fragile X syndrome
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19. Single cell transcriptomics reveals dysregulated cellular and molecular networks in a fragile X syndrome model
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20. Deletion of Fmr1 in Parvalbumin Inhibitory Neurons Leads to Dysregulated Translation and Selective Behavioral Deficits Associated with Fragile X Syndrome
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25. Knockout of the BK β4-subunit promotes a functional coupling of BK channels and ryanodine receptors that mediate a fAHP-induced increase in excitability
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26. Habituation of reflexive and motivated behavior in mice with deficient BK channel function
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27. Proteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric Disorders
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30. Neuronal mechanism of a BK channelopathy in absence epilepsy and dyskinesia
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31. Integrated transcriptome analysis of human iPS cells derived from a fragile X syndrome patient during neuronal differentiation
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32. Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice
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33. Differential regulation of BK channels by fragile X mental retardation protein
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34. Medial prefrontal cortex circuitry and social behaviour in autism
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35. CRL4 antagonizes SCFFbxo7-mediated turnover of cereblon and BK channel to regulate learning and memory
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41. A Screen for Synaptic Growth Mutants Reveals Mechanisms That Stabilize Synaptic Strength
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42. RNA Secondary Structure Modulates FMRP’s Bi-Functional Role in the MicroRNA Pathway
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43. Towards Kinase Inhibitor Therapies for Fragile X Syndrome: Tweaking Twists in the Autism Spectrum Kinase Signaling Network
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44. The role of adiponectin receptors in the regulation of synaptic transmission in the hippocampus
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45. Genetic reduction of MMP-9 in the Fmr1 KO mouse partially rescues prepulse inhibition of acoustic startle response
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47. New Insights Into the Role of Cav2 Protein Family in Calcium Flux Deregulation in Fmr1-KO Neurons
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49. Cortical neurons derived from human pluripotent stem cells lacking FMRP display altered spontaneous firing patterns.
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50. In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome
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54. Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant
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55. Handling FMRP and its molecular partners: Structural insights into Fragile X Syndrome
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56. Targeted pharmacological treatment of autism spectrum disorders: fragile X and Rett syndromes
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57. Modulation of intrinsic excitability as a function of learning within the fear conditioning circuit
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58. Postsynaptic FMRP Regulates Synaptogenesis In Vivo in the Developing Cochlear Nucleus
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59. Loss of fragile X mental retardation protein precedes Lewy pathology in Parkinson’s disease
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60. Metabotropic Modulation of Potassium Channels During Synaptic Plasticity
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61. The Fragile X Mental Retardation Protein Regulates Striatal Medium Spiny Neuron Synapse Density and Dendritic Spine Morphology
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63. Synaptic vesicle dynamic changes in a model of fragile X
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68. Hyperexcitability of Sensory Neurons in Fragile X Mouse Model
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69. Aberrant basal ganglia metabolism in fragile X syndrome: a magnetic resonance spectroscopy study
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71. FMRP Sustains Presynaptic Function via Control of Activity-Dependent Bulk Endocytosis
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72. The Implication of AMPA Receptor in Synaptic Plasticity Impairment and Intellectual Disability in Fragile X Syndrome
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73. Altered A-Type Potassium Channel Function Impairs Dendritic Spike Initiation and Temporoammonic Long-Term Potentiation in Fragile X Syndrome
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74. FMRP regulates GABAA receptor channel activity to control signal integration in hippocampal granule cells
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75. Mechanisms Driving the Emergence of Neuronal Hyperexcitability in Fragile X Syndrome
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79. N-myristoylation regulates the axonal distribution of the Fragile X-related protein FXR2P
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80. Current Approaches to the Pharmacologic Treatment of Core Symptoms Across the Lifespan of Autism Spectrum Disorder
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83. Structural and Functional Abnormalities in the Olfactory System of Fragile X Syndrome Models
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