FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels

Deng, Pan-Yue, Rotman, Ziv, Blundon, Jay A., Cho, Yongcheol, Cui, Jianmin, Cavalli, Valeria, Zakharenko, Stanislav S., Klyachko, Vitaly A.·2013·Neuron

Cited by (355)

Items 301–355 of 355

  1. Shaping Synaptic Learning by the Duration of Postsynaptic Action Potential in a New STDP Model
    Youwei Zheng, Lars Schwabe · 2014 · PLoS ONE
  2. Visualizing Local Protein Synthesis and Its Modulation by FMRP and Visual Experience
    Gervasio Batista, Hannah R. Monday · 2016 · Journal of Neuroscience
  3. Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model
    Pan‐Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A. Klyachko · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model
    Pan‐Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A. Klyachko · 2024 · eLife
  5. Shaping synaptic learning by the duration of the postsynaptic action potential
    Youwei Zheng, Lars Schwabe · 2013 · International Joint Conference on Neural Networks (IJCNN)
  6. Subunits via Electrostatic Interactions 4 β BK Potassium Channels Containing Conopeptide Vt3.1 Preferentially Inhibits
    Cheng‐Wu Chi, Jianmin Cui, Chunguang Wang, Xiaoqin Zou, Kelli McFarland, Xiao Yun Yang, Shan Chang, Longjin Yang · 2014
  7. Feed-forward Inhibitory Circuits in Hippocampus and Their Computational Role in Fragile X Syndrome
    Sarah Wahlstrom‐Helgren · 2016 · Open Scholarship Institutional Repository (Washington University in St. Louis)
  8. FMRP and the Pathophysiology of Fragile X Syndrome
    Stephanie A. Barnes, Sophie R. Thomson, Peter C. Kind, Emily K. Osterweil · 2016 · Elsevier eBooks
  9. The Endocannabinoid System in Fragile X Syndrome
    Henry G. S. Martin, Daniela N. Neuhofer, Olivier J. Manzoni · 2017 · Elsevier eBooks
  10. Neuronal Dysfunction in Fragile X Spectrum Disorders.
    Abigail J. Renoux · 2015 · Deep Blue (University of Michigan)
  11. Cellular and Synaptic Phenotype Compensations Limit Circuit Disruption in Fmr1-KO Mouse Layer 4 Barrel Cortex but Fail to Prevent Deficits in Information Processing
    Aleksander P.F. Domanski, Sam A. Booker, David J. A. Wyllie, John T. R. Isaac, Peter C. Kind · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Moment-to-moment regulation of voltage-gated potassium channel function
    Victoria A. Baronas · 2018 · cIRcle (University of British Columbia)
  13. Human pluripotent stem cells in the research of Fragile X Syndrome
    Michael Telias · 2021 · Elsevier eBooks
  14. Excess ribosomal protein production unbalances translation in Fragile X Syndrome
    Sang S. Seo, Susana R. Louros, Natasha J. Anstey, Miguel A. Gonzalez‐Lozano, Callista B. Harper, Nicholas Verity, Owen Dando, Sophie R. Thomson, Jennifer C. Darnell, Peter C. Kind et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  15. The activation of mGluR4 rescues parallel fiber LTP, motor learning and social behavior in a mouse model of Fragile X Syndrome
    Ricardo Martín, Alberto Samuel Suárez-Pinilla, Nuria García-Font, M. Luisa Laguna-Luque, Juan Carlos López, María Jesús Oset‐Gasque, Agnès Gruart, Jose Maria Delgado-Garcia, Magdalena Torres, José Sánchez‐Prieto · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Faculty Opinions recommendation of Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.
    Eric Hollander, Genoveva Uzunova · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  17. Fragile X-associated disorders
    Randi Jenssen Hagerman · 2022 · Elsevier eBooks
  18. Dichotomous Intrinsic Properties of Adult Accumbens Medium Spiny Neurons Vanish in the Fragile X Mouse Model of Autism
    Gabriele Giua, Olivier Lassalle, Leila Makrini, Emmanuel Valjent, Pascale Chavis, Olivier J. Manzoni · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Fragile X Mental Retardation Protein (FMRP) expression in human nociceptor axons of the spinal dorsal horn— Implications for RNA targeting and localized translation
    Molly E. Mitchell, Lauren C. Cook, Stephanie I. Shiers, Diana Tavares‐Ferreira, Armen N. Akopian, Gregory O. Dussor, Theodore John Price · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  20. Efficient delivery of FMR1 across the blood brain barrier using AAVphp construct in adult FMR1 KO mice demonstrates the feasibility of gene therapy for fragile X syndrome
    Kathryn K. Chadman, Tatyana Adayev, Aishwarya Udayan, Rida Ahmed, Chun‐Ling Dai, Jeffrey H. Goodman, Harry C. Meeker, Natalia Dolzhanskaya, Milen T. Velinov · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  21. Spontaneous Synchronous Network Activity Underlying The Development Of Immature Rodent Medial Prefrontal Cortex
    Johny Helder Da Silva Dias Pires · 2022
  22. Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model
    Pan‐Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A. Klyachko · 2023 · eLife
  23. eLife Assessment: Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse model
    Katalin Tóth · 2023 · eLife
  24. Noisy brain may underlie some of autism’s sensory features
    Holly Barker · 2024 · The Transmitter
  25. Analysis of ribosomes from WT and FMR1 KO human embryonic stem cells
    Tripti Kharbanda, Michelle Ninochka D’Souza, Dasaradhi Palakodeti, Ravi Sondekoppa Muddashetty, Kutti Ragunath Vinothkumar · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Astrocytic contribution to auditory hypersensitivity in a mouse model of fragile X syndrome
    Lara Bergdolt, Alexandria Anding, Ola Alshaqi, Zahra Arbabi, Michael Douchey, Ember Eldridge, Katherine Hoffman, Ashley Reid, Kiran Sapkota, Ragunathan Padmashri et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  27. Late onset of striatal projection neuron hyperexcitability in Fmr1 -/y mice
    Lars Nelson, Michael Janeček, Michael Matarazzo, Yi-Chun Shih, Rui T. Peixoto · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Interaction between neuromuscular junction metabolic requirements in fragile X syndrome and glycogen storage disease models
    Aashi R. Gurijala, Emma Rushton, Shannon N. Leahy, Nichalas Nelson, Charles R. Tessier, Kendal S. Broadie · 2025 · Disease Models & Mechanisms
  29. Age-dependent impairment of dopamine D1 receptor signalling in mouse striatum by FMR1 variant P626L
    Junyi Fu, Wei Jiang, Liping Shen, Jiaming Fu, Xianlai Duan, Detian Liu, Jingyi Long, Shunhua Ye, Lingjia Tang, Yong‐Hong Yi et al. · 2025 · Brain Communications
  30. Associations Between Altered Auditory EEG Markers and Clinical Impairments in Fragile X Syndrome
    Mélodie Proteau-Lemieux, Inga Sophia Knoth, Saeideh Davoudi, Charles-Olivier Martin, Anne-Marie Bélanger, Valérie K. Fontaine, Hazel Maridith Barlahan Biag, Leonard Abbeduto, Sébastien Jacquemont, David R. Hessl et al. · 2025 · Journal of Autism and Developmental Disorders
  31. Early developmental characterization of gap-induced prepulse inhibition and habituation in the Fragile X Syndrome mouse model
    Abdullah Abdullah, Xiuping Liu, Kartikeya Murari, Jun Yan, Ning Cheng · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  32. Additional file 1 of BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory response
    Song, Ahui, Wang, Jingjing, Tong, Yan, Fang, Junyan, Zhang, Yi, Zhang, Huiping, Hongqiang Ruan, Kai Wang, Yingli Liu · 2020 · Figshare
  33. Additional file 2 of Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome
    Kalinowska, Magdalena, Mathijs B. van der Lei, Michael Kitiashvili, Maggie Mamcarz, Mauricio Martins Oliveira, Francesco Longo, Eric Klann · 2022 · Figshare
  34. Additional file 2 of Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome
    Asiminas, Antonis, Booker, Sam A., Owen Dando, Zrinko Kozić, Daisy Arkell, Felicity H. Inkpen, Anna Sumera, Irem Akyel, Peter C. Kind, Emma R. Wood · 2024 · Figshare
  35. Additional file 1 of Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndrome
    Kalinowska, Magdalena, Mathijs B. van der Lei, Michael Kitiashvili, Maggie Mamcarz, Mauricio Martins Oliveira, Francesco Longo, Eric Klann · 2022 · Figshare
  36. Additional file 1 of Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X Syndrome
    Asiminas, Antonis, Booker, Sam A., Owen Dando, Zrinko Kozić, Daisy Arkell, Felicity H. Inkpen, Anna Sumera, Irem Akyel, Peter C. Kind, Emma R. Wood · 2024 · Figshare
  37. Targeted drug development in fragile X syndrome: Molecular medicine as a key tool in clinical pharmacology
    Dragana D. Protic, Maja Stojković, Dejan B. Budimirovic · 2025 · Medicinska istrazivanja
  38. Alterations in electroencephalography signals in female fragile X syndrome mouse model on a C57BL/6J background
    Bosong Wang, Asim A. Ahmed, Kartikeya Murari, Ning Cheng · 2026 · Physiology & Behavior
  39. Extracellular spike waveform analysis reveals cell type-specific changes in the superior colliculus of fragile X mice
    Gourav Sharma, Ashley L. Russell, Karen G. Dixon, Romina Fusha, Jason W. Triplett · 2026 · Open Biology
  40. Electroretinography biomarkers indicate disrupted visual processing in Fragile X syndrome
    Qianyi Pu, Naomi Bennett, Tejas C. Sekhar, Mary T. Stanley, Elizabeth Berry‐Kravis · 2026 · Journal of Neurodevelopmental Disorders
  41. Plasticité d'un réseau du cortex à barils lors de l'apprentissage et dans un modèle murin du syndrome de l'X fragile
    Maxime Fieschi · 2013 · theses.fr (ABES)
  42. Effets de la modulation des canaux potassium SK et Kv4 sur les déficits moteurs et cognitifs de la maladie de Parkinson
    Sabrine Aidi-Knani · 2014 · theses.fr (ABES)
  43. Studying Neuronal Connectivity in the Mouse Brain in Normal Condition and Fragile X Syndrome
    Matthias Georg Haberl · 2014 · theses.fr (ABES)
  44. The role of intrinsic neuronal excitability for Prelimbic network function
    Rafael De Sa · 2019 · theses.fr (ABES)
  45. Dissecting the role of calcium signaling in Fragile X syndrome
    Sara Castagnola · 2019 · theses.fr (ABES)
  46. Anomalies sensorielles visuelles du Syndrome de l'X fragile, contribution rétinienne au phénotype de dys-sensibilité
    Chloé Felgerolle · 2019
  47. Pathophysiological consequences of a Fragile X missense mutation
    Marta Prieto Garcia · 2020 · theses.fr (ABES)
  48. Identifying therapeutic targets for the treatment of Fragile X Syndrome : Implications for Autism Spectrum Disorders
    William Fyke · 2021
  49. Rôle de la phosphodiestérase 2A dans la physiopathologie du syndrome de l’X fragile
    Sébastien Delhaye · 2021 · theses.fr (ABES)
  50. BKCa channels as therapeutic targets in neurodevelopmental disorders : focus on acoustic dysfunction
    Celeste Ferraguto · 2024 · theses.fr (ABES)
  51. Socio-communicative and nucleus accumbens core dysfunctions in fragile X syndrome
    Gabriele Giua · 2023 · theses.fr (ABES)
  52. Altered axonal initial segment development links circuit and K v 7 dysfunction in an Fmr1 knockout rat
    Jack F. Webster, Marie Pronot, Michael Alan Cousin · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  53. Early Developmental Characterization of Gap-Induced Prepulse Inhibition and Habituation of Auditory Startle Response in a Fragile X Syndrome Mouse Model
    Abdullah Abdullah, Xiuping Liu, Kartikeya Murari, Jun Yan, Ning Cheng · 2026 · Developmental Neuroscience
  54. Dysregulation of cAMP-PKA-mediated mechanisms disrupts basal synaptic function in the absence of presynaptic FMRP
    Simon Lecomte, Bruna Correa de Mira, Noëlle Grosjean, Christophe Mulle · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  55. Loss of Fmr1 causes subnucleus-specific decreases in dendritic complexity in mediodorsal thalamus
    Alena Kizimenko, Polina N. Lyuboslavsky, Audrey C. Brumback · 2026 · Brain Structure and Function