FMRP regulates neurotransmitter release and synaptic information transmission by modulating action potential duration via BK channels
Deng, Pan-Yue, Rotman, Ziv, Blundon, Jay A., Cho, Yongcheol, Cui, Jianmin, Cavalli, Valeria, Zakharenko, Stanislav S., Klyachko, Vitaly A.·2013·Neuron
Cited by (355)
Items 301–355 of 355
- Shaping Synaptic Learning by the Duration of Postsynaptic Action Potential in a New STDP ModelYouwei Zheng, Lars Schwabe · 2014 · PLoS ONE
- Visualizing Local Protein Synthesis and Its Modulation by FMRP and Visual ExperienceGervasio Batista, Hannah R. Monday · 2016 · Journal of Neuroscience
- Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelPan‐Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A. Klyachko · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelPan‐Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A. Klyachko · 2024 · eLife
- Shaping synaptic learning by the duration of the postsynaptic action potentialYouwei Zheng, Lars Schwabe · 2013 · International Joint Conference on Neural Networks (IJCNN)
- Subunits via Electrostatic Interactions 4 β BK Potassium Channels Containing Conopeptide Vt3.1 Preferentially InhibitsCheng‐Wu Chi, Jianmin Cui, Chunguang Wang, Xiaoqin Zou, Kelli McFarland, Xiao Yun Yang, Shan Chang, Longjin Yang · 2014
- Feed-forward Inhibitory Circuits in Hippocampus and Their Computational Role in Fragile X SyndromeSarah Wahlstrom‐Helgren · 2016 · Open Scholarship Institutional Repository (Washington University in St. Louis)
- FMRP and the Pathophysiology of Fragile X SyndromeStephanie A. Barnes, Sophie R. Thomson, Peter C. Kind, Emily K. Osterweil · 2016 · Elsevier eBooks
- The Endocannabinoid System in Fragile X SyndromeHenry G. S. Martin, Daniela N. Neuhofer, Olivier J. Manzoni · 2017 · Elsevier eBooks
- Neuronal Dysfunction in Fragile X Spectrum Disorders.Abigail J. Renoux · 2015 · Deep Blue (University of Michigan)
- Cellular and Synaptic Phenotype Compensations Limit Circuit Disruption in Fmr1-KO Mouse Layer 4 Barrel Cortex but Fail to Prevent Deficits in Information ProcessingAleksander P.F. Domanski, Sam A. Booker, David J. A. Wyllie, John T. R. Isaac, Peter C. Kind · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Moment-to-moment regulation of voltage-gated potassium channel functionVictoria A. Baronas · 2018 · cIRcle (University of British Columbia)
- Human pluripotent stem cells in the research of Fragile X SyndromeMichael Telias · 2021 · Elsevier eBooks
- Excess ribosomal protein production unbalances translation in Fragile X SyndromeSang S. Seo, Susana R. Louros, Natasha J. Anstey, Miguel A. Gonzalez‐Lozano, Callista B. Harper, Nicholas Verity, Owen Dando, Sophie R. Thomson, Jennifer C. Darnell, Peter C. Kind et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- The activation of mGluR4 rescues parallel fiber LTP, motor learning and social behavior in a mouse model of Fragile X SyndromeRicardo Martín, Alberto Samuel Suárez-Pinilla, Nuria García-Font, M. Luisa Laguna-Luque, Juan Carlos López, María Jesús Oset‐Gasque, Agnès Gruart, Jose Maria Delgado-Garcia, Magdalena Torres, José Sánchez‐Prieto · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Faculty Opinions recommendation of Increased Excitation-Inhibition Ratio Stabilizes Synapse and Circuit Excitability in Four Autism Mouse Models.Eric Hollander, Genoveva Uzunova · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Fragile X-associated disordersRandi Jenssen Hagerman · 2022 · Elsevier eBooks
- Dichotomous Intrinsic Properties of Adult Accumbens Medium Spiny Neurons Vanish in the Fragile X Mouse Model of AutismGabriele Giua, Olivier Lassalle, Leila Makrini, Emmanuel Valjent, Pascale Chavis, Olivier J. Manzoni · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Fragile X Mental Retardation Protein (FMRP) expression in human nociceptor axons of the spinal dorsal horn— Implications for RNA targeting and localized translationMolly E. Mitchell, Lauren C. Cook, Stephanie I. Shiers, Diana Tavares‐Ferreira, Armen N. Akopian, Gregory O. Dussor, Theodore John Price · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Efficient delivery of FMR1 across the blood brain barrier using AAVphp construct in adult FMR1 KO mice demonstrates the feasibility of gene therapy for fragile X syndromeKathryn K. Chadman, Tatyana Adayev, Aishwarya Udayan, Rida Ahmed, Chun‐Ling Dai, Jeffrey H. Goodman, Harry C. Meeker, Natalia Dolzhanskaya, Milen T. Velinov · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Spontaneous Synchronous Network Activity Underlying The Development Of Immature Rodent Medial Prefrontal CortexJohny Helder Da Silva Dias Pires · 2022
- Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelPan‐Yue Deng, Ajeet Kumar, Valeria Cavalli, Vitaly A. Klyachko · 2023 · eLife
- eLife Assessment: Circuit-based intervention corrects excessive dentate gyrus output in the Fragile X mouse modelKatalin Tóth · 2023 · eLife
- Noisy brain may underlie some of autism’s sensory featuresHolly Barker · 2024 · The Transmitter
- Analysis of ribosomes from WT and FMR1 KO human embryonic stem cellsTripti Kharbanda, Michelle Ninochka D’Souza, Dasaradhi Palakodeti, Ravi Sondekoppa Muddashetty, Kutti Ragunath Vinothkumar · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Astrocytic contribution to auditory hypersensitivity in a mouse model of fragile X syndromeLara Bergdolt, Alexandria Anding, Ola Alshaqi, Zahra Arbabi, Michael Douchey, Ember Eldridge, Katherine Hoffman, Ashley Reid, Kiran Sapkota, Ragunathan Padmashri et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Late onset of striatal projection neuron hyperexcitability in Fmr1 -/y miceLars Nelson, Michael Janeček, Michael Matarazzo, Yi-Chun Shih, Rui T. Peixoto · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Interaction between neuromuscular junction metabolic requirements in fragile X syndrome and glycogen storage disease modelsAashi R. Gurijala, Emma Rushton, Shannon N. Leahy, Nichalas Nelson, Charles R. Tessier, Kendal S. Broadie · 2025 · Disease Models & Mechanisms
- Age-dependent impairment of dopamine D1 receptor signalling in mouse striatum by FMR1 variant P626LJunyi Fu, Wei Jiang, Liping Shen, Jiaming Fu, Xianlai Duan, Detian Liu, Jingyi Long, Shunhua Ye, Lingjia Tang, Yong‐Hong Yi et al. · 2025 · Brain Communications
- Associations Between Altered Auditory EEG Markers and Clinical Impairments in Fragile X SyndromeMélodie Proteau-Lemieux, Inga Sophia Knoth, Saeideh Davoudi, Charles-Olivier Martin, Anne-Marie Bélanger, Valérie K. Fontaine, Hazel Maridith Barlahan Biag, Leonard Abbeduto, Sébastien Jacquemont, David R. Hessl et al. · 2025 · Journal of Autism and Developmental Disorders
- Early developmental characterization of gap-induced prepulse inhibition and habituation in the Fragile X Syndrome mouse modelAbdullah Abdullah, Xiuping Liu, Kartikeya Murari, Jun Yan, Ning Cheng · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 1 of BKCa channels regulate the immunomodulatory properties of WJ-MSCs by affecting the exosome protein profiles during the inflammatory responseSong, Ahui, Wang, Jingjing, Tong, Yan, Fang, Junyan, Zhang, Yi, Zhang, Huiping, Hongqiang Ruan, Kai Wang, Yingli Liu · 2020 · Figshare
- Additional file 2 of Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndromeKalinowska, Magdalena, Mathijs B. van der Lei, Michael Kitiashvili, Maggie Mamcarz, Mauricio Martins Oliveira, Francesco Longo, Eric Klann · 2022 · Figshare
- Additional file 2 of Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X SyndromeAsiminas, Antonis, Booker, Sam A., Owen Dando, Zrinko Kozić, Daisy Arkell, Felicity H. Inkpen, Anna Sumera, Irem Akyel, Peter C. Kind, Emma R. Wood · 2024 · Figshare
- Additional file 1 of Deletion of Fmr1 in parvalbumin-expressing neurons results in dysregulated translation and selective behavioral deficits associated with fragile X syndromeKalinowska, Magdalena, Mathijs B. van der Lei, Michael Kitiashvili, Maggie Mamcarz, Mauricio Martins Oliveira, Francesco Longo, Eric Klann · 2022 · Figshare
- Additional file 1 of Experience-dependent changes in hippocampal spatial activity and hippocampal circuit function are disrupted in a rat model of Fragile X SyndromeAsiminas, Antonis, Booker, Sam A., Owen Dando, Zrinko Kozić, Daisy Arkell, Felicity H. Inkpen, Anna Sumera, Irem Akyel, Peter C. Kind, Emma R. Wood · 2024 · Figshare
- Targeted drug development in fragile X syndrome: Molecular medicine as a key tool in clinical pharmacologyDragana D. Protic, Maja Stojković, Dejan B. Budimirovic · 2025 · Medicinska istrazivanja
- Alterations in electroencephalography signals in female fragile X syndrome mouse model on a C57BL/6J backgroundBosong Wang, Asim A. Ahmed, Kartikeya Murari, Ning Cheng · 2026 · Physiology & Behavior
- Extracellular spike waveform analysis reveals cell type-specific changes in the superior colliculus of fragile X miceGourav Sharma, Ashley L. Russell, Karen G. Dixon, Romina Fusha, Jason W. Triplett · 2026 · Open Biology
- Electroretinography biomarkers indicate disrupted visual processing in Fragile X syndromeQianyi Pu, Naomi Bennett, Tejas C. Sekhar, Mary T. Stanley, Elizabeth Berry‐Kravis · 2026 · Journal of Neurodevelopmental Disorders
- Plasticité d'un réseau du cortex à barils lors de l'apprentissage et dans un modèle murin du syndrome de l'X fragileMaxime Fieschi · 2013 · theses.fr (ABES)
- Effets de la modulation des canaux potassium SK et Kv4 sur les déficits moteurs et cognitifs de la maladie de ParkinsonSabrine Aidi-Knani · 2014 · theses.fr (ABES)
- Studying Neuronal Connectivity in the Mouse Brain in Normal Condition and Fragile X SyndromeMatthias Georg Haberl · 2014 · theses.fr (ABES)
- The role of intrinsic neuronal excitability for Prelimbic network functionRafael De Sa · 2019 · theses.fr (ABES)
- Dissecting the role of calcium signaling in Fragile X syndromeSara Castagnola · 2019 · theses.fr (ABES)
- Anomalies sensorielles visuelles du Syndrome de l'X fragile, contribution rétinienne au phénotype de dys-sensibilitéChloé Felgerolle · 2019
- Pathophysiological consequences of a Fragile X missense mutationMarta Prieto Garcia · 2020 · theses.fr (ABES)
- Identifying therapeutic targets for the treatment of Fragile X Syndrome : Implications for Autism Spectrum DisordersWilliam Fyke · 2021
- Rôle de la phosphodiestérase 2A dans la physiopathologie du syndrome de l’X fragileSébastien Delhaye · 2021 · theses.fr (ABES)
- BKCa channels as therapeutic targets in neurodevelopmental disorders : focus on acoustic dysfunctionCeleste Ferraguto · 2024 · theses.fr (ABES)
- Socio-communicative and nucleus accumbens core dysfunctions in fragile X syndromeGabriele Giua · 2023 · theses.fr (ABES)
- Altered axonal initial segment development links circuit and K v 7 dysfunction in an Fmr1 knockout ratJack F. Webster, Marie Pronot, Michael Alan Cousin · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Early Developmental Characterization of Gap-Induced Prepulse Inhibition and Habituation of Auditory Startle Response in a Fragile X Syndrome Mouse ModelAbdullah Abdullah, Xiuping Liu, Kartikeya Murari, Jun Yan, Ning Cheng · 2026 · Developmental Neuroscience
- Dysregulation of cAMP-PKA-mediated mechanisms disrupts basal synaptic function in the absence of presynaptic FMRPSimon Lecomte, Bruna Correa de Mira, Noëlle Grosjean, Christophe Mulle · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Loss of Fmr1 causes subnucleus-specific decreases in dendritic complexity in mediodorsal thalamusAlena Kizimenko, Polina N. Lyuboslavsky, Audrey C. Brumback · 2026 · Brain Structure and Function