Autism-Associated Neuroligin-3 Mutations Commonly Disrupt Tonic Endocannabinoid Signaling
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Items 201–287 of 287
- Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal–Glial Synapses and Reduced Expression in Nlgn3R451C MiceMadushani Herath, Hyun‐Jung Cho, Ulrika Marklund, Ashley Edwin Franks, Joel C. Bornstein, Elisa L. Hill‐Yardin · 2023 · Biomolecules
- Conserved and divergent processing of neuroligin and neurexin genes: from the nematode C. elegans to humanFernando Calahorro · 2014 · Invertebrate Neuroscience
- Perspectives on the Role of Endocannabinoids in Autism Spectrum DisordersMason L. Yeh, Eric S. Levine · 2017 · OBM Neurobiology
- Hypomyelination in autism-associated neuroligin-3 mutant mice impairs parvalbumin interneuron excitability, gamma oscillations, and sensory discriminationYongxiang He, Jiong Li, Wei Zheng, Junhong Liu, Zhao-Jun Dong, Yang Lü, Shuting Tang, Yanping Zou, Tianyu Gao, Yuqian Yang et al. · 2025 · Nature Communications
- Neuroligin-3 Regulates Excitatory Synaptic Transmission and EPSP-Spike Coupling in the Dentate Gyrus In VivoJulia Muellerleile, Matej Vnencak, Angelo Ippolito, Dilja Krueger‐Burg, Tassilo Jungenitz, Stephan Wolfgang Schwarzacher, Peter Jedlička · 2021 · Molecular Neurobiology
- Impact of converging sociocultural and substance-related trends on US autism rates: combined geospatiotemporal and causal inferential analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2022 · European Archives of Psychiatry and Clinical Neuroscience
- A perspective on molecular signalling dysfunction, its clinical relevance and therapeutics in autism spectrum disorderSushmitha S. Purushotham, Neeharika M. N. Reddy, Michelle Ninochka D’Souza, Nilpawan Roy Choudhury, Anusa Ganguly, Niharika Gopalakrishna, Ravi Sondekoppa Muddashetty, James Premdoss Clement · 2022 · Experimental Brain Research
- Explorations and perspectives on the neurobiological bases of autism spectrum disorderJohn J. Foxe, Sophie Molholm, Stéphane J. Baudouin, Mark T. Wallace · 2018 · European Journal of Neuroscience
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- Deletion of neuroligins from astrocytes does not detectably alter synapse numbers or astrocyte cytoarchitecture by maturitySamantha Rose Golf, Justin H. Trotter, Jinzhao Wang, George Nakahara, Xiao Han, Marius Wernig, Thomas Christian Südhof · 2023 · eLife
- Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autismMichelle Bridi, Nancy Luo, Grace Kim, Benjamin J Menarchek, Rachel A. Lee, Bryan A. Rodríguez, Daniel Severín, Cristian Moreno, Altagracia Contreras, Christian Wesselborg et al. · 2024 · iScience
- Synaptic Targets and Cellular Sources of CB1 Cannabinoid Receptor and Vesicular Glutamate Transporter‐3 Expressing Nerve Terminals in Relation to GABAergic Neurons in the Human Cerebral CortexPéter Somogyi, Sawa Horie, Istvan Paul Lukacs, Emily Hunter, Barbara Sárkány, Tim J. Viney, James Livermore, Puneet Plaha, Richard J. Stacey, Olaf Ansorge et al. · 2025 · European Journal of Neuroscience
- Impaired cecal motility and secretion alongside expansion of gut-associated lymphoid tissue in the Nlgn3R451C mouse model of autismChalystha Yie Qin Lee, Gayathri K. Balasuriya, Madushani Herath, Ashley Edwin Franks, Elisa L. Hill‐Yardin · 2023 · Scientific Reports
- Génétique des schizophrénies : mise en perspective des schizophrénies à début précoce et autres pathologies du développementClaudine Laurent‐Levinson, Marianna Giannitelli, David Cohen, Douglas F. Levinson · 2013 · Neuropsychiatrie de l Enfance et de l Adolescence
- The Genetic and Epigenetic Basis Involved in the Pathophysiology of ASD: Therapeutic ImplicationsMaria Carmen Carrascosa-Romero, Carlos de Cabo · 2017 · InTech eBooks
- Potential therapeutic uses of cannabinoids to treat behavioural problems in children and adolescents with developmental disordersDaryl Efron · 2021 · Australian Journal of General Practice
- Astrocytic Neuroligins Are Not Required for Synapse Formation or a Normal Astrocyte CytoarchitectureSamantha Rose Golf, Justin H. Trotter, George Nakahara, Thomas Christian Südhof · 2023
- Human-Mouse Chimeric Brain Models to Study Human Glial-Neuronal and Macroglial-Microglial InteractionsMengmeng Jin, Ziyuan Ma, Haiwei Zhang, Ava V. Papetti, Rui Dang, Alessandro C. Stillitano, Lisa Zou, Steven A. Goldman, Peng Jiang · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Faster Gastrointestinal Transit, Reduced Small Intestinal Smooth Muscle Tone and Dysmotility in the Nlgn3R451C Mouse Model of AutismSuzanne Hosie, Tanya Abo-Shaban, Kevin Mou, Gayathri K. Balasuriya, Mitra Mohsenipour, Mohammed Uthman A. Alamoudi, Rhiannon T. Filippone, Gabrielle Therese Belz, Ashley Edwin Franks, Joel C. Bornstein et al. · 2024 · International Journal of Molecular Sciences
- Endocannabinoids and disrupted synchronous oscillations in autism spectrum disordersStephen I. Deutsch, Jessica A. Burket, Maria R. Urbano · 2016 · Future Neurology
- Electrophysiology of Endocannabinoid SignalingAlessandra Musella, Diego Centonze · 2022 · Methods in molecular biology
- State-dependent coupling of hippocampal oscillationsBrijesh Modi, Matteo Guardamagna, Federico Stella, Marilena Griguoli, Enrico Cherubini, Francesco Paolo Battaglia · 2023 · eLife
- Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out MiceJulia Muellerleile, Matej Vnencak, Mohammad Valeed Ahmed Sethi, Tassilo Jungenitz, Stephan Wolfgang Schwarzacher, Peter Jedlička · 2023 · eNeuro
- Perturbation of 3D nuclear architecture, epigenomic aging and dysregulation, and cannabinoid synaptopathy reconfigures conceptualization of cannabinoid pathophysiology: part 2—Metabolome, immunome, synaptomeAlbert Stuart Reece, Gary Kenneth Hulse · 2023 · Frontiers in Psychiatry
- Autism Spectrum DisorderKylie O’Brien, Philip Blair · 2021 · Springer eBooks
- Slc6a20a Heterozygous and Homozygous Mutant Mice Display Differential Behavioral and Transcriptomic ChangesJunhyung Kim, Junyeop Daniel Roh, Seongbin Kim, Hyojin Kang, Mihyun H. Bae, Eunjoon Kim · 2022 · Frontiers in Molecular Neuroscience
- Genetic dissection of the endocannabinoid system and how it changed our knowledge of cannabinoid pharmacology and mammalian physiologyBeat Lutz · 2014 · Wiley eBooks
- The Endocannabinoid System in the Control of BehaviorEdgar Soria Gómez, Mathilde Metna‐Laurent, Luigi Bellocchio, Arnau Busquets-García, Giovanni Marsicano · 2017 · Wiley eBooks
- Synaptic protein mutations in autismAnn Katrin Sauer, John A. Walsh, Darragh Curran, Nazanin Zohourian, Janelle E. Stanton, Ioannis Zabetakis, James A. L. Brown, Andreas Martin Grabrucker · 2026 · Neurobiology of Disease
- Analyses of Human Genetic Data to Identify Clinically Relevant Domains of NeuroliginsAlexander W. Lehr, Kathryn F McDaniel, Katherine W. Roche · 2024 · Genes
- Deletion of Neuroligins from Astrocytes Does Not Detectably Alter Synapse Numbers or Astrocyte Cytoarchitecture by MaturitySamantha Rose Golf, Justin H. Trotter, Jinzhao Wang, George Nakahara, Xiao Han, Marius Wernig, Thomas Christian Südhof · 2025 · eLife
- Extracellular neuroligin-ICAM5 coupling drives dendritic growth via actin remodelingCydric Geyskens, Brigitt Raux, Nuno Apóstolo, Ellis Boonen, Jeroen Vandensteen, Beatriz Marques, João Machado, llkem Kumru, Julie Nys, Eline Creemers et al. · 2026 · iScience
- Unraveling the Role of Neuroligin3 in Autism Spectrum Disorders: Pathophysiological Insights and Targeted TherapiesFatima Azzahrae El Yacoubi, Mohamed Oukabli, Azeddine Ibrahimi, Hassan Kisra, Mounia Bensaid · 2023 · CNS & Neurological Disorders - Drug Targets
- Cannabis Compounds: Potential Therapy for Neurological DiseaseMariana Babayeva, Zvi G. Loewy · 2024 · IntechOpen eBooks
- Multivalent cannabinoid epigenotoxicities and multigenerational agingAlbert Stuart Reece, Gary Kenneth Hulse · 2025 · Elsevier eBooks
- Geospatiotemporal and causal inferential analysis of United States congenital anomalies as a function of multiple cannabinoid- and substance-exposures: Phenocopying thalidomide and hundred megabase-scale genotoxicityAlbert Stuart Reece, Gary Kenneth Hulse · 2025 · Elsevier eBooks
- Linked rise of cannabis use and autism incidence demonstrated by close three-level geospatiotemporal relationships, USA, 1990–2011Albert Stuart Reece, Gary Kenneth Hulse · 2025 · Elsevier eBooks
- Enhanced CB1 receptor function in GABAergic neurons mediates hyperexcitability and impaired sensory-driven synchrony of cortical circuits in Fragile X Syndrome model miceD. Gonzalez, CR Jonak, Matteo Bernabucci, Gemma Molinaro, K. Collins, SA Assad, Jay R. Gibson, Devin K. Binder, Kimberly M. Huber · 2025 · Molecular Psychiatry
- Perinatal LC-ω-3-PUFA supplementation offsets prenatal THC-induced cognitive deficit via sex-specific modulation of hippocampal neuroplasticityGianluca Lavanco, Valentina Castelli, Cesare D'Amico, Salvatore Feo, Martin Kuchař, Petr Palivec, Anna Brancato, Carla Cannizzaro · 2026 · European Journal of Pharmacology
- The Ecology of Wild Cannabis sativaErnest Small · 2016 · CRC Press eBooks
- The Role of Neuroligins in the Cerebellum Highlights the Diversity of Synapse-Specifying MoleculesJessica E. Messier · 2017 · Journal of Neuroscience
- Cannabis Chemistry: Cannabinoids in Cannabis, Humans, and Other SpeciesErnest Small · 2016 · CRC Press eBooks
- The endocannabinoid system in autism spectrum disorderJonathan A. Costello, Michelle Roche · 2025 · Handbook of behavioral neuroscience
- Proteinkomplexe an inhibitorischen Synapsen in psychiatrischen StörungenDilja Krueger‐Burg · 2019 · BIOspektrum
- Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autismMichelle Bridi, Nancy Luo, Grace Kim, Caroline O’Ferrall, Ruchit V. Patel, Sarah J. Bertrand, Sujatha Kannan, Alfredo Kirkwood · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Caecal dysfunction in the NL3 R451C mouse model of autismChalystha Yie Qin Lee, Gayathri K. Balasuriya, Madushani Herath, Ashley Edwin Franks, Elisa L. Hill‐Yardin · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Causal association between mTOR-dependent circulating protein levels and autism spectrum disorder: a Mendelian randomization studyJingfen Fu, Meiyuan Dong, Ling‐Ling Chen, Chunhui Du, Ze Yu, Hongqiang Wang · 2024 · Research Square
- Deletion of Neuroligins from Astrocytes Does Not Detectably Alter Synapse Numbers or Astrocyte Cytoarchitecture by MaturitySamantha Rose Golf, Justin H. Trotter, Jinzhao Wang, George Nakahara, Xiao Han, Marius Wernig, Thomas Christian Südhof · 2025 · eLife
- Synaptic networks shape clinical phenotypes in neurodevelopmental disorders: An integrative clinical, genetic and biological perspectiveJuliana Ribeiro‐Constante, Júlia Romagosa, Alfonso Oyarzábal, Enric X. Martin Rull, Àngels García‐Cazorla · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Molecular Pathways in Autistic Spectrum DisordersLouise Gallagher, Sanbing Shen, Richard Anney · 2015 · Key issues in mental health (Online)/Key issues in mental health (Print)
- The Endocannabinoid System in Fragile X SyndromeHenry G. S. Martin, Daniela Neuhofer, Olivier J. Manzoni · 2017 · Elsevier eBooks
- Autismo ed infi ammazioneDario Siniscalco · 2017 · PNEI REVIEW
- Role of adhesion proteins Neuroligin 2 and IgSF9b in the amygdala anxiety circuitryOlga Babaev · 2018 · eDiss (Georg-August-Universität Göttingen)
- Is the Use of Cannabis During Pregnancy a Risk Factor for Autism?Sarah Crawford · 2019 · Autism - Open Access
- Cannabinoid and Marijuana NeurobiologyBertha Kalifon Madras · 2020 · Springer eBooks
- Неканоническая активность эндоканнабиноидов и их рецепторов в центральных и периферических синапсахOlga P. Balezina, Ekaterina O. Tarasova, А.Е. Гайдуков · 2021 · Biochemistry (Moscow)
- Is the Use of Cannabis during Pregnancy a Risk Factor for Autism?2020 · Advances in Neurology and Neuroscience
- Faculty Opinions recommendation of Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior.Giovanni Marsicano, Arnau Busquets-García · 2018 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Roles of the autism candidate genes neuroligin-3, neuroligin-4, and neurobeachin in synaptic plasticity ande excitation-inhibition balance in the dentate gyrusJulia Muellerleile · 2022 · Publication Server of Goethe University Frankfurt am Main (Goethe University Frankfurt)
- Avaliação dos efeitos do canabidiol sobre as consequências comportamentais induzidas pelo tratamento com o ácido valproico durante o período embrionário do zebrafishKarla Cristinne Mancini Costa · 2023 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Deletion of neuroligins from astrocytes does not detectably alter synapse numbers or astrocyte cytoarchitecture by maturitySamantha Rose Golf, Justin H. Trotter, Jinzhao Wang, George Nakahara, Xiao Han, Marius Wernig, Thomas Christian Südhof · 2023 · eLife
- Genes and their Involvement in the Pathogenesis of Autism Spectrum Disorder: Insights from Earlier Genetic StudiesRishabh Chaudhary, Emma Steinson · 2023 · Springer eBooks
- Impaired metabotropic glutamate type 5 receptor signaling in the dorsal striatum of the R451C-neuroligin 3 mouse model of Autism Spectrum DisorderMaria Meringolo, Martina Montanari, Simona D’Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos et al. · 2024 · Research Square
- Sleepless nights and social plights: medial septum GABAergic hyperactivity in a neuroligin 3–deficient autism modelClaire E. Cho, Dahee Jung, Reesha R. Patel · 2024 · Journal of Clinical Investigation
- Impaired metabotropic glutamate type 5 receptor signaling in the dorsal striatum of the R451C-neuroligin 3 mouse model of Autism Spectrum DisorderMaria Meringolo, Martina Montanari, Simona D’Antoni, Giuseppina Martella, Ilham El Atiallah, Giulia Ponterio, Annalisa Tassone, Ingrid Reverte, Daniele Caprioli, Georgios Strimpakos et al. · 2025 · Research Square
- Close parallels between cannabis use and deteriorating US Mental Health at four levels supports and extends the epidemiological salience of demonstrated causal mental health relationships: A geospatiotemporal studyAlbert Stuart Reece, Gary Kenneth Hulse · 2025 · Elsevier eBooks
- Potential mechanisms of endocannabinoid releaseCarl R. Lupica · 2025 · Handbook of behavioral neuroscience
- Endocannabinoid regulation of hippocampal circuitsCoralie Berthoux, Pablo E. Castillo · 2025 · Handbook of behavioral neuroscience
- Additional file 6 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 1 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 1 of Imbalance of flight–freeze responses and their cellular correlates in the Nlgn3−/y rat model of autismNatasha J. Anstey, Vijayakumar Kapgal, Tiwari, Shashank, Thomas C. Watson, Anna Karina Hugger Toft, Owen Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson et al. · 2022 · Figshare
- Additional file 4 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 2 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 8 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 5 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 3 of Co-occurrence across time and space of drug- and cannabinoid- exposure and adverse mental health outcomes in the National Survey of Drug Use and Health: combined geotemporospatial and causal inference analysisAlbert Stuart Reece, Gary Kenneth Hulse · 2020 · Figshare
- Additional file 2 of Imbalance of flight–freeze responses and their cellular correlates in the Nlgn3−/y rat model of autismNatasha J. Anstey, Vijayakumar Kapgal, Tiwari, Shashank, Thomas C. Watson, Anna Karina Hugger Toft, Owen Dando, Felicity H. Inkpen, Paul S. Baxter, Zrinko Kozić, Adam D. Jackson et al. · 2022 · Figshare
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- Autismus-Spektrum-StörungKylie O’Brien, Philip Blair · 2026 · Springer eBooks
- NLGN3 autism variants have distinct functional impact on synapses and sleep behavior in DrosophilaRebekah Townsley, Jonathan C. Andrews, Saurabh Srivastav, Sharayu V. Jangam, Shabab B. Hannan, Oguz Kanca, Paul C. Marcogliese, Shinya Yamamoto, Michael F. Wangler · 2026 · PLoS Genetics