Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

Šišková, Zuzana, Justus, Daniel, Kaneko, Hiroshi, Friedrichs, Detlef, Henneberg, Niklas, Beutel, Tatjana, Pitsch, Julika, Schoch, Susanne +3 more·2014·Neuron

Cited by (321)

Items 201–300 of 321

  1. Cognitive rejuvenation through partial reprogramming of engram cells
    Gabriel Berdugo‐Vega, Cèsar Sierra, Simone Astori, Veronika Calati, Jules Orsat, Marianne Julie Scoglio, Carmen Sandi, Johannes Gräff · 2026 · Neuron
  2. Altered dorsal CA1 neuronal population coding in the APP/PS1 mouse model of Alzheimer’s disease
    Udaysankar Chockanathan, Emily J. Warner, Loel C. Turpin, M. Kerry O’Banion, Krishnan Padmanabhan · 2020 · Scientific Reports
  3. A Novel Form of Compensation in the Tg2576 Amyloid Mouse Model of Alzheimer’s Disease
    Attila Somogyi, Zoltán Katonai, Alán Alpár, Ervin Wolf · 2016 · Frontiers in Cellular Neuroscience
  4. Modeling neurodegenerative and neurodevelopmental disorders in theDrosophilamushroom body
    Aaron Stahl, Seth M. Tomchik · 2024 · Learning & Memory
  5. Dehydroepiandrosterone Attenuates Astroglial Activation, Neuronal Loss and Dendritic Degeneration in Iron-Induced Post-Traumatic Epilepsy
    Chandra Prakāsh, Shyam Sunder Rabidas, Jyoti Tyagi, Deepak Sharma · 2023 · Brain Sciences
  6. Emerging Mechanisms Underpinning Neurophysiological Impairments in C9ORF72 Repeat Expansion-Mediated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia
    Iris-Stefania Pasniceanu, Manpreet Singh Atwal, Cleide Dos Santos Souza, Laura Ferraiuolo, Matthew R. Livesey · 2021 · Frontiers in Cellular Neuroscience
  7. Modulation of the Aβ-Peptide-Aggregation Pathway by Active Compounds From Platycladus orientalis Seed Extract in Alzheimer’s Disease Models
    Yan Li, Xiang Ming He, Yufan Jin, Jiawei Wang, Fengying Liang, Rongrong Pei, Peibo Li, Yonggang Wang, Weiwei Su · 2020 · Frontiers in Aging Neuroscience
  8. Neurophysiological effects of human-derived pathological tau conformers in the APPKM670/671NL.PS1/L166P amyloid mouse model of Alzheimer’s disease
    Sean Tok, Hervé Maurin, C. Delay, Dries Crauwels, Nikolay V. Manyakov, Wim Van der Elst, Dieder Moechars, Wilhelmus H. I. M. Drinkenburg · 2022 · Scientific Reports
  9. R-carvedilol, a potential new therapy for Alzheimer’s disease
    Jinjing Yao, S.R. Wayne Chen · 2022 · Frontiers in Pharmacology
  10. Nanoscale reorganisation of synaptic proteins in Alzheimer's disease
    Wang‐Hui Zhu, Xiaoxu Yang, Xu‐Zhuo Gou, Shumei Fu, Jiahui Chen, Feng Gao, Yong Shen, Danlei Bi, Ai‐Hui Tang · 2023 · Neuropathology and Applied Neurobiology
  11. Neuron‐intrinsic origin of hyperexcitability during early pathogenesis of Alzheimer’s disease
    Dasfne Lee‐Liu, Christian Enrique González-Billault · 2021 · Journal of Neurochemistry
  12. Hyperactive neuronal networks enhance tau spread in an Alzheimer’s disease mouse model
    Aaron J Barbour, Keegan Hoag, Eli J. Cornblath, Abigail Chavez, Alfredo Lucas, Xiaofan Li, Sydney E Zebrowitz, Chloe Hassman, Omar Vazquez, Sharon X. Xie et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  13. Synaptic adhesion molecule protocadherin‐γC5 mediates β‐amyloid‐induced neuronal hyperactivity and cognitive deficits in Alzheimer's disease
    Min Su, Erying Xuan, Xiangyi Sun, Gaojie Pan, Dandan Li, Honghua Zheng, Yun‐wu Zhang, Yanfang Li · 2024 · Journal of Neurochemistry
  14. Electrophysiological insights into Alzheimer's disease: A review of human and animal studies
    Kirsten Calvin, Adam M. McNeela, Amanda M. Leisgang Osse, Guncha Bhasin, Matthew Ridenour, Jefferson W. Kinney, J.M. Hyman · 2024 · Neuroscience & Biobehavioral Reviews
  15. Altered membrane properties but unchanged intrinsic excitability and spontaneous postsynaptic currents in an aged APPswe/PS1dE9 model of Alzheimer’s disease
    Shane M. Ohline, Xinhuai Liu, Mohamed F. Ibrahim, Bruce M. Mockett, Ruth M. Empson, Wickliffe C. Abraham, Karl J. Iremonger, Peter P. Jones · 2022 · Frontiers in Cellular Neuroscience
  16. The medial septum-hippocampus-lateral septum circuitry in spatial memory: linking healthy function to early Alzheimer’s disease and translational opportunities
    Yujie Song, Junjun Ni, Hong Qing, Zhenzhen Quan · 2025 · Translational Neurodegeneration
  17. Familial Alzheimer’s Disease Neurons Bearing Mutations in PSEN1 Display Increased Calcium Responses to AMPA as an Early Calcium Dysregulation Phenotype
    Helena Targa Dias Anastacio, Natalie Matosin, Lezanne Ooi · 2024 · Life
  18. Aβ1-42 Oligomer Injection Model: Understanding Neural Dysfunction and Contextual Memory Deficits in Dorsal CA1
    Min-Kaung-Wint-Mon, Dai Mitsushima · 2025 · Journal of dementia and Alzheimer's disease
  19. The expression of G protein-coupled receptor kinase 5 and its interaction with dendritic marker microtubule-associated protein-2 after status epilepticus
    Xiangchang Zeng, Siyu Chen, Qing Gao, Wenjing Zong, Dejian Jiang, Guirong Zeng, Luping Zhou, Lulu Chen, Wei Luo, Jian Ru Xiao et al. · 2017 · Epilepsy Research
  20. Amyloid-β Oligomers Induce Only Mild Changes to Inhibitory Bouton Dynamics
    Marvin Ruiter, Christine Lützkendorf, Jian Liang, Corette J. Wierenga · 2021 · Journal of Alzheimer s Disease Reports
  21. What has Electron Microscopy Contributed to Alzheimer's Research?
    Stavros Balogiannis · 2015 · Future Neurology
  22. MorphoGNN: Morphological Embedding for Single Neuron with Graph Neural Networks
    Tianfang Zhu, Gang Yao, Dongli Hu, Chuangchuang Xie, Hui Gong, Anan Li · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Estimating the synaptic density deficit in Alzheimer’s disease using multi-contrast CEST imaging
    Syed Salman Shahid, Mario Džemidžić, Elizabeth R. Butch, Erin Jarvis, Scott E. Snyder, Yu‐Chien Wu · 2024 · PLoS ONE
  24. Gene deletion of Pregnancy-associated Plasma Protein-A (PAPP-A) improves pathology and cognition in an Alzheimer's disease mouse model
    Laurie K. Bale, Sally A. West, Naomi M. Gades, Darren J. Baker, Cheryl A. Conover · 2024 · Experimental Neurology
  25. Impact of Dendritic Spine Loss on Excitability of Hippocampal CA1 Pyramidal Neurons: A Computational Study of Early Alzheimer Disease
    Chengju Tian, Isabel Reyes, Alexandra Johnson, Arjun V. Masurkar · 2025 · Hippocampus
  26. Sex-specific factors and APOEε4 genotype alter functional connectivity at middle age
    Bonnie H. Lee, Andrew J. McGovern, Stephanie E. Lieblich, Selene V. Mitchell, Jie Yin, Jonathan R. Epp, Liisa A.M. Galea · 2025 · Psychoneuroendocrinology
  27. Alzheimer’s disease pathology degrades an NMDA receptor-dependent spontaneous activity pattern in cortico-hippocampal circuits
    Robert A. Ellingford, Sam Harris, Marten Kehring, Rikesh M. Rajani, Francesca Kar Wey Lam, David R. Graykowski, Dorothea Böken, Lindsay A. Welikovitch, Anita Khasnavis, Rhiannon Laban et al. · 2026 · Neuron
  28. From synapses to circuits and back: Bridging levels of understanding in animal models of Alzheimer's disease
    Udaysankar Chockanathan, Krishnan Padmanabhan · 2022 · European Journal of Neuroscience
  29. The Edible Seaweed Gelidium amansii Promotes Structural Plasticity of Hippocampal Neurons and Improves Scopolamine-induced Learning and Memory Impairment in Mice
    Md. Mohibbullah, Michael Yordan Pringgo Wicaksono, Md. Abdul Hannan, Raju Dash, Maria Dyah Nur Meinita, Jae‐Suk Choi, Yong-Ki Hong, Il Soo Moon · 2022 · CNS & Neurological Disorders - Drug Targets
  30. Super-resolution microscopy as a drug discovery tool
    Lauren Toms, Lorna FitzPatrick, Philip Auckland · 2025 · SLAS DISCOVERY
  31. Promotion of neuroinflammation in select hippocampal regions in a mouse model of perimenopausal Alzheimer’s disease
    Roberta Marongiu, Jimcy Platholi, Laibaik Park, Fangmin Yu, Garrett Sommer, Clara Woods, Teresa A. Milner, Michael J. Glass · 2025 · Frontiers in Molecular Biosciences
  32. Astrovascular decoupling in awake 5×FAD mice is associated with reduced astrocytic calcium
    Ruei‐Lung Lin, Sophiya L. Sims, Nicholas A. Wright, Leopoldine B Galopin, Blaine E. Weiss, Susan D. Kraner, Jacquelyn E. Rhinehart, Ting‐Hsuan Lu, Pradoldej M Sompol, Christopher Mark Norris et al. · 2025 · Alzheimer s & Dementia
  33. Role of intracellular Ca2+ stores for an impairment of visual processing in a mouse model of Alzheimer's disease
    Nithi Asavapanumas, Bianca Brawek, Peter Martus, Olga Garaschuk · 2018 · Neurobiology of Disease
  34. Linking Motoneuron PIC Location to Motor Function in Closed-Loop Motor Unit System Including Afferent Feedback: A Computational Investigation
    Hojeong Kim · 2020 · eNeuro
  35. Seizures and Epilepsy in Dementia: Diagnosis and Management
    Laura Mantoan Ritter, Christer Nilsson · 2021 · Springer eBooks
  36. Transcranial Direct Current Stimulation as an Alternative Treatment in Patients with Alzheimer's Disease
    Yeo Jin Kim · 2017 · Brain & Neurorehabilitation
  37. Ultrastructural characterization of dark microglia during aging in a mouse model of Alzheimer’s disease pathology and in human post-mortem brain samples
    Marie‐Kim St‐Pierre, Micaël Carrier, Fernando Gonzàlez Ibáñez, Eva Šimončičová, Marie‐Josée Wallman, Luc Vallières, Martin Parent, Marie‐Ève Tremblay · 2022 · Research Square
  38. Small fibre neuropathy in Fabry disease: a human-derived neuronal in vitro disease model
    Thomas C. Klein, Julia Grüner, Maximilian Breyer, Jan A. Schlegel, Nicole Michelle Schottmann, Lukas Hofmann, Kevin Gauss, Rebecca Audrey Mease, Christoph Erbacher, Laura Finke et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  39. Dendrite injury triggers neuroprotection in Drosophila models of neurodegenerative disease
    Sydney E. Prange, Isha N. Bhakta, Daria Sysoeva, Grace E. Jean, Anjali Madisetti, Hieu H. N. Le, Ly U. Duong, Patrick T. Hwu, Jaela G. Melton, Katherine L. Thompson-Peer · 2024 · Scientific Reports
  40. Super resolution microscopy is poised to reveal new insights into the formation and maturation of dendritic spines
    Cristina M. Robinson, Mikin R. Patel, Donna J. Webb · 2016 · F1000Research
  41. Morphological Bases of Neuronal Hyperexcitability in Neurodegeneration
    Ti‐Fei Yuan, Bo Peng, Sergio Eduardo de Carvalho Machado, Óscar Arias-Carrión · 2015 · CNS Neuroscience & Therapeutics
  42. Integrated Proteomics Identifies Neuritin (NRN1) as a Mediator of Cognitive Resilience to Alzheimer’s Disease
    Cheyenne D. Hurst, Derian A. Pugh, Measho H. Abreha, Duc Minh Duong, Eric B. Dammer, David Alan Bennett, Jeremy H. Herskowitz, Nicholas T. Seyfried · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  43. Genetic context controls early microglia-synaptic interactions in mouse models of Alzheimer’s disease
    Sarah E. Heuer, Kelly J. Keezer, Amanda A. Hewes, Kristen D. Onos, Kourtney C. Graham, Gareth R. Howell, Erik B. Bloss · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  44. Endogenous tau released from human ReNCell VM cultures by neuronal activity is phosphorylated at multiple sites
    Ghadir Sindi, Sazan Ismael, Reaz Uddin, Kira G. Slepchenko, Robert A. Colvin, Daewoo Lee · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  45. Synaptic and synchronic impairments in subcortical brain regions associated with early non-cognitive dysfunction in Alzheimer’s disease
    Nicolás Riffo-Lepe, Juliana González-Sanmiguel, Lorena Armijo‐Weingart, Paulina Saavedra, David Hernandez, Gerson Ramos, Loreto San Martín, Luis Gerardo Aguayo · 2025 · Neural Regeneration Research
  46. Hippocampal Interneurons Shape Spatial Coding Alterations in Neurological Disorders
    Juliane Midori Ikebara, Renata Silva Jorge, Luciana Simões Rafagnin Marinho, Guilherme Shigueto Vilar Higa, Avishek Adhikari, Fernando MCV Reis, Fernando S. Borges, Henning Ulrich, Silvia Honda Takada, Roberto De Pasquale et al. · 2025 · Molecular Neurobiology
  47. Dendritic retraction contributes to spine density recovery following denervation in vitro
    Davide Greco, Alexander Drakew, Tassilo Jungenitz, Thomas Deller · 2025 · Neurobiology of Disease
  48. The rise and deceleration of neuronal excitability in aging and Alzheimer’s disease: Mechanisms, implications, and therapeutic targets
    Osvaldo Delbono, Zhong‐Min Wang, Marı́a Laura Messi · 2025 · Ageing Research Reviews
  49. GABA B Receptor signaling in CA1 Pyramidal Cells is not Regulated by Aging in the APP/PS1 Mouse Model of Amyloid Pathology
    S. Meftah, Max A Wilson, Jamie Elliott, Lauren McLay, Vladimirs Dobrovolskis, Samuel Rosencrans, Lewis W. Taylor, Claudia Mugnaini, Rafaela Mostallino, Claire S. Durrant et al. · 2026 · eNeuro
  50. Differential disruptions in population coding along the dorsal-ventral axis of CA1 in the APP/PS1 mouse model of Aβ pathology
    Udaysankar Chockanathan, Krishnan Padmanabhan · 2024 · PLoS Computational Biology
  51. Mechanisms of the Pathogenesis of Alzheimer’s Disease: The Role of the Basal Forebrain
    Valentina F. Kitchigina, Irina Yu. Popova, Liubov Shubina · 2025 · Neuroscience and Behavioral Physiology
  52. Compensatory Changes in Mauthner Neurons in Goldfish Induced by Sensory Stimulation and Application of β-Amyloid
    Nadezhda R. Tiras, I. B. Mikheyeva, Gulnara Z. Mikhailova, Nadezhda A. Penkova, Ye. N. Bezgina · 2019 · Neuroscience and Behavioral Physiology
  53. Networks-Mediated Spreading of Pathology in Neurodegenerative Diseases
    Yasser Iturria‐Medina, Alan Charles Evans · 2021 · Springer eBooks
  54. Edge Density Imaging Identifies White Matter Biomarkers of Late-Life Obesity and Cognition
    Maxwell Bond Wang, Farzaneh Rahmani, Tammie L.S. Benzinger, Cyrus A. Raji · 2022 · Aging and Disease
  55. A biologically inspired repair mechanism for neuronal reconstructions with a focus on human dendrites
    Moritz Groden, Hannah Mössinger, Barbara Schaffran, Javier DeFelipe, Ruth Benavides‐Piccione, Hermann Cuntz, Peter Jedlička · 2024 · PLoS Computational Biology
  56. 3D Mapping Reveals Network-specific Amyloid Progression and Subcortical Susceptibility
    Rebecca G. Canter, Heejin Choi, Joyce Wang, Lauren Ashley Watson, CG Yao, Fatema Abdurrob, Stephanie M. Bousleiman, Ivana Delalle, Kwanghun Chung, L-H Tsai · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  57. Robust spatial memory maps encoded in networks with transient connections
    Andrey Babichev, Dmitriy Morozov, Yuri A. Dabaghian · 2017 · arXiv (Cornell University)
  58. Neuronal hyperactivity in a LRRK2-G2019S cellular model of Parkinson’s Disease
    Edinson Lucumi Moreno, Siham Hachi, Sarah Nickels, Khalid I.W. Kane, Masha Moein, Jens Christian Schwamborn, Alexander Skupin, Pieter Vanden Berghe, Ronan M. T. Fleming · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  59. Somatostatin and the pathophysiology of Alzheimer’s disease
    Victor Nascimento Almeida · 2023 · Qeios
  60. Alzheimer’s disease protective allele of Clusterin modulates neuronal excitability through lipid-droplet-mediated neuron-glia communication
    Xiaojie Zhao, Yan Li, Siwei Zhang, Ari Sudwarts, Hanwen Zhang, Alena Kozlova, Matthew J. Moulton, Lindsey D. Goodman, Zhiping P. Pang, Alan R. Sanders et al. · 2024 · medRxiv
  61. Early-Stage Corticostriatal Circuit Hyperactivity Impairs Cholinergic Function and Cognitive Flexibility in an Alzheimer’s Model
    Yufei S. Huang, Xuan Xie, Zhenbo Huang, Ruifeng Chen, Himanshu Gangal, Xuehua Wang, Karienn A. de Souza, Julia Hunter, Xin Yi Wu, Doodipala Samba Reddy et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  62. ZCCHC17 knockdown phenocopies Alzheimer’s disease-related loss of synaptic proteins and hyperexcitability
    Giuseppe P. Cortese, Anne Marie W. Bartosch, Harrison Xiao, Yelizaveta Gribkova, Tiffany G. Lam, Elentina K. Argyrousi, Sharanya Sivakumar, Christopher L. Cardona, Andrew F. Teich · 2024 · Journal of Neuropathology & Experimental Neurology
  63. Role of polyphenols in epilepsy: from the perspective of gut microbiota
    Xiaoxue Xu, Jian Shi, Guiyang Cai, Chao Ma, Wuyang Wang, Rui Feng, Tomasz Boczek, Yinsi Tang, Zhenwei He, Feng Guo · 2024 · Food Science and Human Wellness
  64. Role of Tropomodulins in brain physiology and pathology
    Chuan Hong, Xiaopeng Liu, Zhou Zhou, Yuan Xing, Zixuan Cao, Yan-Zhong Chang, Guofen Gao · 2025 · Neurobiology of Disease
  65. Amyloid β–dependent neuronal silencing through synaptic decoupling
    Yonghai Zhang, Hsing-Jung Chen-Engerer, Kuan Zhang, Benedikt Zott, Zsuzsanna Varga, Yang Chen, Xiaowei Chen, Jia Hongbo, Bert J. Sakmann, Israel Nelken et al. · 2025 · Proceedings of the National Academy of Sciences
  66. Disruption of ClC-3-mediated 2Cl−/H+ exchange leads to behavioural deficits and thalamic atrophy
    Carina Balduin, Guanxiao Qi, Michael Schöneck, Verena Trinkel, Sarah Schemmert, Gustavo A. Guzman, Stefanie Bungert‐Plümke, Malte Klüssendorf, Bernd Neumaier, Dirk Feldmeyer et al. · 2025 · Scientific Reports
  67. Multimodal MRI Reveals Cerebral and Vascular Amyloid‐Driven Myeloarchitectural Disorganization in a Mouse Model of Alzheimer's Disease
    Syed Salman Shahid, Xuan Li, Mario Džemidžić, Erin Jarvis, Yomna Takieldeen, A. Wang, Donna M. Wilcock, Yu‐Chien Wu · 2026 · NMR in Biomedicine
  68. Reduced inhibition, bursting, and accelerated oscillations drive early hippocampal hyperactivity in Alzheimer’s disease in vivo
    Soraya Meftah, Sungmin Kang, Mingshan Liu, Xingran Wang, Ada Nursel Topçu, Maialen Abad, Áron Kőszeghy, Long Wan, Conor Mullin, Lida Zoupi et al. · 2026 · Communications Biology
  69. Prodromal changes in cortical neuron physiology before amyloid pathology in a mild model of Alzheimer’s disease
    Katarina D. Milicevic, Ana Cristina Abreu, Gowri Chandran, Yan M. D. Zhu, Xiangyou Hu, Violetta O. Ivanova, Madhav Jami, Bernd Simon, Ignacio Fernández, Riqiang Yan et al. · 2026 · Scientific Reports
  70. Sex differences in the effects of chronic stress and oxycodone associative learning on glial markers in rat hippocampus
    Ma’ayan Hirschkorn, Annabelle Kim, Garrett Sommer, Sydney Warwick, Lennox Gregoire, Yan Zhou, Joshua F. Kogan, Jason D. Gray, Teresa A. Milner · 2026 · Neuroscience
  71. Innovations in Neurophysiology and Its Role in Neuropsychiatry
    Didem Öz, Görsev Yener · 2022 · Nöro Psikiyatri Arşivi
  72. Is Alzheimer's disease a manifestation of brain quantum decoherence resulting from mitochondrial and microtubular deterioration?
    T.W. Nichols · 2023 · Journal of Multiscale Neuroscience
  73. Dopamine Improves Resistance of Dendrites of Mauthner Neurons to Destruction Induced by Sensory Stimulation and Application of Β-Amyloid
    Nadezhda R. Tiras, I. B. Mikheeva, Gulnara Z. Mikhailova, Nadezhda A. Penkova, S. S. Khutsyan · 2020 · Bulletin of Experimental Biology and Medicine
  74. Seizure susceptibility in Alzheimer’s disease
    Karen E. Reyes-Marin, Jonathan Adrian Zegarra-Valdivia, Ángel Núñez · 2021 · Medical Research Archives
  75. Redox imbalance and oxidative stress in Mecp2 deficient neurons
    Karolina Can · 2016
  76. Localized calcium accumulations prime synapses for phagocyte removal in cortical neuroinflammation
    Mehrnoosh Jafari, Adrian-Minh Schumacher, Nicolas Snaidero, Tradite Neziraj, Emily M. Ullrich Gavilanes, Tanja Jürgens, Juan Daniel Flórez Weidinger, Stephanie S. Schmidt, Eduardo Beltrán, Nellwyn Hagan et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  77. Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimer’s disease
    Roberta Marongiu, Jimcy Platholi, Laibaik Park, Fangmin Yu, Garrett Sommer, Clara Woods, Teresa A. Milner, Michael J. Glass · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  78. Role of Non-Coding Rna in Sculpting Neurons
    Mayuresh Anant Sarangdhar · 2017 · Revista de Fomento Social
  79. Semi-automatische Rekonstruktion von Neuronen
    My-Tien Nguyen, Julia Tran, Marie E. Müller, Adrian Wanner · 2019 · BIOspektrum
  80. Moderation of neural excitation promotes longevity
    Nektarios Tavernarakis · 2019 · Nature
  81. Elucidating the function of brain resting‐state networks and their relation to the pathophysiology of neuropsychiatric diseases
    Ken‐ichiro Yamashita · 2020 · Neurology and Clinical Neuroscience
  82. Sunday driver mediates multi-compartment Golgi outposts defects induced by amyloid precursor protein
    Qianqian Du, Jin Chang, Guo Cheng, Yinyin Zhao, Wei Jie Zhou · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  83. Dendritic Excitability and Protein Kinase C Activity Regulate Purkinje Neuron Dendrite Degeneration in Cerebellar Ataxia
    Ravi Chopra · 2020 · Deep Blue (University of Michigan)
  84. The Different Sensitivity of Dendritic Degeneration in Hippocampal and Cortical Neurons to Estrogen Decline in Female Aging Mice
    Lin Cheng Yang, Shuai Zhang, Yan-Ru Wang, Tingting Li, Siyu Huang, Yang Qu, Xiaobin An, Jing Ai · 2021 · Research Square
  85. Opto-Magneto-Electrical Nanoactuators for Wireless Cell Stimulation
    Yue Zhang · 2020 · Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya)
  86. Astrocytic C-X-C motif chemokine ligand-1 mediates β-amyloid-induced synaptotoxicity
    Beatriz Gomez Perez‐Nievas, Louisa Johnson, Paula Beltran-Lobo, Martina M. Hughes, Luciana Gammallieri, Francesca Tarsitano, Monika A. Myszczynska, Irina Vázquez-Villaseñor, María Jiménez-Sánchez, Claire Troakes et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  87. Functional spreading of hyperexcitability induced by human and synthetic intracellular Aβ oligomers
    Eduardo J. Fernández-Pérez, Braulio Muñoz, Denisse Bascuñán, Christian Peters, Nicolás Riffo-Lepe, María Paz Espinoza, Peter James Morgan, Caroline Filippi, Romain Bourboulou, Urmi Sengupta et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  88. Modelling the contributions to hyperexcitability in a mouse model of Alzheimer’s disease
    Martin Mittag, Laura Mediavilla, Stefan Remy, Hermann Cuntz, Peter Jedlička · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  89. HCN2 Deficiency Causes Cognitive Impairments via Inducing Hyperexcitability of dCA1 Pyramidal Neurons in a Mouse Model of Alzheimer's Disease
    Xiaoqin Zhang, Yi-Bei Dong, Hejia Jiang, Le Xu, Jing Wang, Yiping Zhang, Huaqiang Zhu, Fei-Yuan Dong, Linbo Hu, Xinyi Zhu et al. · 2022 · SSRN Electronic Journal
  90. Spatial coding in aging and Alzheimer's disease
    Fang, Yue · 2022
  91. Additional file 3 of Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model
    Li Yang, Ke Zhu, Li, Ning, Xiaotong Wang, Xuansheng Xiao, Linying Li, Lijuan Li, Ying He, Jinglan Zhang, Jiaoyang Wo et al. · 2021 · Figshare
  92. Additional file 2 of Reversible GABAergic dysfunction involved in hippocampal hyperactivity predicts early-stage Alzheimer disease in a mouse model
    Li Yang, Ke Zhu, Li, Ning, Xiaotong Wang, Xuansheng Xiao, Linying Li, Lijuan Li, Ying He, Jinglan Zhang, Jiaoyang Wo et al. · 2021 · Figshare
  93. (outdated draft) Somatostatin and the pathophysiology of Alzheimer’s disease
    Victor Nascimento Almeida · 2024 · Qeios
  94. The role of the basal forebrain in the pathogenesis of Alzheimer’s disease
    Valentina F. Kitchigina, Irina Yu. Popova, Liubov Shubina · 2024 · Журнал высшей нервной деятельности им И П Павлова
  95. Amyloid pathology compresses dynamic range and degrades spatial coding in an Alzheimer’s mouse model
    Mary Ann Go, Kathrine E. Clarke, Yimei Li, Seigfred V. Prado, Beatriz R. F. Teixeira, Mingyang Gao, Jess J Yu, Simon R. Schultz · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  96. Potential Disease-Modifying Pharmacological Therapy for Alzheimer’s Disease by Protecting Synapses Via Prevention of Hyperexcitability and E/I Imbalance
    Swagata Ghatak, Stuart A. Lipton · 2025 · Springer eBooks
  97. CACNA1C TS-II variants alter single-cell dynamics in computational models of cortical pyramidal cells
    M. Moore, Marja‐Leena Linne, Tuomo Mäki‐Marttunen · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Early Aβ-induced changes in the enteric nervous system and the gut: structure, function, and motility
    Manuela Gries, Hannah Ramona Puhl, Steven Schulte, Anne Christmann, Stephanie Rommel, Marko K. Baller, Monika Martin, Tobias Hartmann, Marcus O.W. Grimm, Karl‐Herbert Schäfer · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  99. TREK1 upregulation is an endogenous mechanism delaying cognitive decline in Alzheimer’s Disease
    Tuhina Mitra, Ranjit Bhoi, Triparna Chakraborty, Asmit Moharana, Vaishnav Manoj, Hiral Rawal, Swagata Ghatak · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  100. Molecular pathways underlying amyloid precursor protein–mediated regulation of adult-born neurons
    Hai-Dong Hu, Huidong Li, Yu Chen, Jianwen Zhou, Jian Chen, Qihong Tang, Xiaoshan Chen, Jinxiang Jiang, Mengyao Sun, Dongjing Jia et al. · 2025 · Neural Regeneration Research