Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

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Enhancement of intrinsic neuronal excitability‐mediated by a reduction in hyperpolarization‐activated cation current (Ih) in hippocampal CA1 neurons in a rat model of traumatic brain injury

Karimi, S. A., Hosseinmardi, N., Sayyah, M., Hajisoltani, R., & Janahmadi, M. (2020) · Hippocampus · doi:10.1002/hipo.23270 · Cited by 18

Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice

Rechnitz, O., Slutsky, I., Morris, G., & Derdikman, D. (2021) · Current Biology · doi:10.1016/j.cub.2021.05.039 · Cited by 11

Dendritic spine head diameter predicts episodic memory performance in older adults

Walker, C. K., Liu, E., Greathouse, K. M., Adamson, A. B., Wilson, J. P., Poovey, E. H., Curtis, K. A., Muhammad, H. M., Weber, A. J., Bennett, D. A., et al. (2024) · Science Advances · doi:10.1126/sciadv.adn5181 · Cited by 12

Alzheimer’s disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity

Pavešković, M., De-Paula, R. B., Ojelade, S. A., Tantry, E. K., Kochukov, M. Y., Bao, S., Veeraragavan, S., Garza, A. R., Srivastava, S., Song, S., et al. (2024) · Human Molecular Genetics · doi:10.1093/hmg/ddae115 · Cited by 11

Structural and functional remodeling of neural networks in β-amyloid driven hippocampal hyperactivity

Li, J., Liu, Y., Yin, C., Zeng, Y., & Mei, Y. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102468 · Cited by 13

Structural and functional alterations of neurons derived from sporadic Alzheimer’s disease hiPSCs are associated with downregulation of the LIMK1-cofilin axis

Sollazzo, R., Puma, D. D. L., Aceto, G., Paciello, F., Colussi, C., Vita, M. G., Giuffrè, G. M., Pastore, F., Casamassa, A., Rosati, J. D., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01632-3 · Cited by 10

Dysregulated Plasma Membrane Turnover Underlying Dendritic Pathology in Neurodegenerative Diseases

Chung, C. G., Park, S. S., Park, J. H., & Lee, S. B. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.556461 · Cited by 12

Control of hippocampal synaptic plasticity by microglia–dendrite interactions depends on genetic context in mouse models of Alzheimer's disease

Heuer, S. E., Keezer, K. J., Hewes, A. A., Onos, K. D., Graham, K., Howell, G. R., & Bloss, E. B. (2023) · Alzheimer s & Dementia · doi:10.1002/alz.13440 · Cited by 11

Pathobiolgy and Management of Alzheimer's Disease

Kim, H., & Chung, J. Y. (2021) · Chonnam Medical Journal · doi:10.4068/cmj.2021.57.2.108 · Cited by 11

Walnut-derived peptides cross the blood–brain barrier and ameliorate Aβ-induced hypersynchronous neural network activity

Min, W., Dang, Q., Li, Z., Zhao, X., Shen, Y., Li, F., & Liu, C. (2024) · Food Research International · doi:10.1016/j.foodres.2024.115302 · Cited by 11

Thymosin beta 4 as an Alzheimer disease intervention target identified using human brain organoids

Zeng, P.-M., Sun, X.-Y., Li, Y., Wu, W.-D., Huang, J., Cao, D.-D., Qian, P.-J., Ju, X.-C., & Luo, Z. (2025) · Stem Cell Reports · doi:10.1016/j.stemcr.2025.102601 · Cited by 14

Neuronal APOE4-induced early hippocampal network hyperexcitability in Alzheimer’s disease pathogenesis

Tabuena, D. R., Jang, S.-S., Grone, B. P., Yip, O., Jones, E. A. A., Blumenfeld, J. R., Liang, Z., Mann, R. S., Li, Y., Necula, D., et al. (2026) · Nature Aging · doi:10.1038/s43587-026-01096-0 · Cited by 17

ZCCHC17 Modulates Neuronal RNA Splicing and Supports Cognitive Resilience in Alzheimer's Disease

Bartosch, A. M. W., Youth, E. H. H., Hansen, S., Wu, Y., Buchanan, H. M., Kaufman, M. E., Xiao, H., Koo, S. Y., Ashok, A., Sivakumar, S., et al. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.2324-22.2023 · Cited by 10

The effect of brain-derived neurotrophic factor on radiation-induced neuron architecture impairment is associated with the NFATc4/3 pathway

Zhang, Q., Li, X., He, R., Ma, Q., Sun, R., Ji, S., Wang, B., & Tian, Y. (2017) · Brain Research · doi:10.1016/j.brainres.2017.12.032 · Cited by 10

Melatonin Rescues the Dendrite Collapse Induced by the Pro-Oxidant Toxin Okadaic Acid in Organotypic Cultures of Rat Hilar Hippocampus

Solís‐Chagoyán, H., Domínguez-Alonso, A., Valdés‐Tovar, M., Argueta, J., Sánchez-Florentino, Z. A., Calixto, E., & Benítez‐King, G. (2020) · Molecules · doi:10.3390/molecules25235508 · Cited by 11

Activity-dependent release of phosphorylated human tau from Drosophila neurons in primary culture

Ismael, S., Sindi, G., Colvin, R. A., & Lee, D. (2021) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2021.101108 · Cited by 12

Neurofilament light-associated connectivity in young-adult Huntington’s disease is related to neuronal genes

McColgan, P., Gregory, S., Zeun, P., Zarkali, A., Johnson, E. B., Parker, C. S., Fayer, K., Lowe, J., Nair, A., Estevez‐Fraga, C., et al. (2022) · Brain · doi:10.1093/brain/awac227 · Cited by 9

Endogenous Modulators of NMDA Receptor Control Dendritic Field Expansion of Cortical Neurons

Jorratt, P., Říčný, J., Leibold, C., & Ovsepian, S. V. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-03147-0 · Cited by 9

Early Astrocytic Dysfunction Is Associated with Mistuned Synapses as well as Anxiety and Depressive-Like Behavior in the App NL - F Mouse Model of Alzheimer’s Disease

Portal, B., Södergren, M., Borrell, T. P. I., Giraud, R., Metzendorf, N. G., Hultqvist, G., Nilsson, P., & Lindskog, M. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-231461 · Cited by 10

30th Annual Computational Neuroscience Meeting: CNS*2021–Meeting Abstracts

Arora, K., Zulfiqar, I., Schultheiss, H., Martino, F. D., Gulban, O. F., Lage‐Castellanos, A., & Moerel, M. (2021) · Journal of Computational Neuroscience · doi:10.1007/s10827-021-00801-9 · Cited by 9

Inhibitory interneurons in Alzheimer’s disease

Vargová, G., Vogels, T., Kostecká, Z., & Hromádka, T. (2018) · Bratislavské lekárske listy/Bratislava medical journal · doi:10.4149/bll_2018_038 · Cited by 9

Dendritic complexity change in the triple transgenic mouse model of Alzheimer’s disease

Zhang, Y., Xiao, Z., He, Z., Chen, J., Wang, X., & Jiang, L. (2020) · PeerJ · doi:10.7717/peerj.8178 · Cited by 9

Voltage-Gated Na+ Channels in Alzheimer’s Disease: Physiological Roles and Therapeutic Potential

Baumgartner, T. J., Haghighijoo, Z., Goode, N. A., Dvorak, N. M., Arman, P., & Laezza, F. (2023) · Life · doi:10.3390/life13081655 · Cited by 10

HCN2 deficiency correlates with memory deficits and hyperexcitability of dCA1 pyramidal neurons in Alzheimer’s disease

Zhang, X., Zhang, Y., Zhang, T., Wang, J., Liu, C., Shang, Q. S., Wei, X., Zhu, H., Shen, H., & Sun, B. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01704-y · Cited by 9

Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer’s disease

Alcantara‐Gonzalez, D., Kennedy, M., Criscuolo, C., Botterill, J. J., & Scharfman, H. E. (2025) · Alzheimer s Research & Therapy · doi:10.1186/s13195-025-01747-1 · Cited by 10

A Positive Allosteric Modulator of the SERCA Pump Rescues Hippocampal Neuronal Circuits Dysfunction and Cognitive Defects in a Mouse Model of Alzheimer's Disease

Gerasimov, E., Rakovskaya, A., Pchitskaya, E. I., Власова, О. Л., Dahl, R. S., & Борисович, Б. И. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.2337-24.2025 · Cited by 10

Tau pathology reprograms glucose metabolism to support cortical hyperexcitability, excitatory/inhibitory imbalance, and sleep loss

Irmen, R. E., Turner, S. M., Snipes, J. A., Schloss, K. H., Wang, X., Williams, H. C., Velmurugan, G. V., Hunt, J. B., Li, J., Sullivan, P. G., et al. (2026) · npj Dementia · doi:10.1038/s44400-025-00054-8 · Cited by 11

Morphological Bases of Neuronal Hyperexcitability in Neurodegeneration

Yuan, T., Peng, B., Machado, S. E. D. C., & Arias-Carrión, Ó. (2015) · CNS Neuroscience & Therapeutics · doi:10.1111/cns.12439 · Cited by 3

Modelling the contributions to hyperexcitability in a mouse model of Alzheimer’s diseasePreprint

Mittag, M., Mediavilla, L., Remy, S., Cuntz, H., & Jedlička, P. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.29.494500

Synaptic Remodeling in Alzheimer’s Disease Alters the Input-Output Properties of Pyramidal Neurons

Sanderson, K. W. (2025) · The Mouseion at the JAXlibrary (Jackson Laboratory)

Dendritic Impulse Propagation is Altered in Neocortical Pyramidal Neurons of Tg2576 Mice, an Animal Model of Alzheimer's Disease

Katonai, Z., Somogyi, A., & Wolf, E. (2015) · European Psychiatry · doi:10.1016/s0924-9338(15)30621-0

Abnormal excitability of oblique dendrites implicated in early Alzheimer's: a computational study

Morse, T. M. (2010) · Frontiers in Neural Circuits · doi:10.3389/fncir.2010.00016 · Cited by 43