Pathological Tau Disrupts Ongoing Network Activity
Menkes-Caspi, Noa, Yamin, Hagar G., Kellner, Vered, Spires-Jones, Tara L., Cohen, Dana, Stern, Edward A.·2015·Neuron
Cited by (184)
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- Failure in a population: Tauopathy disrupts homeostatic set-points in emergent dynamics despite stability in the constituent neuronsJames N. McGregor, Clayton A. Farris, Sahara Ensley, Aidan M Schneider, Leandro J. Fosque, Chao Wang, Elizabeth I. Tilden, Yuqi Liu, Jianhong Tu, Halla Elmore et al. · 2024 · Neuron
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- Sexually dimorphic age‐related molecular differences in the entorhinal cortex of cognitively intact elderly: Relation to early Alzheimer's changesXinlu Chen, Jennifer Monteiro Fortes, Yuting Hu, Juliet van Iersel, Kang‐Ning He, Joop J. van Heerikhuize, Rawien A. Balesar, Dick Frans Swaab, Ai‐Min Bao · 2023 · Alzheimer s & Dementia
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- Mechanismen der Alzheimer-KrankheitMarc Aurel Busche, Mathias Staufenbiel, Michael Willem, Christian Haass, Hans Förstl · 2016 · Der Nervenarzt
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- The Reciprocal Interaction Between Sleep and Alzheimer’s DiseaseSam Harris, Tom Schwerd-Kleine, Byung Il Lee, Marc Aurel Busche · 2021 · Advances in experimental medicine and biology
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- Visual Evoked Potentials as an Early-Stage Biomarker in the rTg4510 Tauopathy Mouse ModelAleksandra Parka, Christiane Volbracht, Benjamin J. Hall, Jesper F. Bastlund, Maiken Nedergaard, Bettina Laursen, Paolo Botta, Florence Sotty · 2023 · Journal of Alzheimer s Disease
- K369I Tau Mice Demonstrate a Shift Towards Striatal Neuron Burst Firing and Goal-directed BehaviourMax Mo, Marie E. Jönsson, Miranda A. Mathews, Daniel M. Johnstone, Yazi Diana Ke, Lars Matthias Ittner, Bernard W. Balleine, Teri M. Furlong, Aaron J. Camp · 2020 · Neuroscience
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- Tau pathology leads to lonely non-traveling slow waves that mediate human memory impairmentOmer Sharon, Xi Chen, Jason Dude, Vyoma D. Shah, Yo‐El S. Ju, WJ Jagust, Matthew P. Walker · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Pathogenic tau in the mouse locus coeruleus produces noradrenergic hyperactivity and neuropsychiatric phenotypes reminiscent of early Alzheimer’s diseaseAnu Korukonda, Harris E. Blankenship, Korey Kam, Dilpreet Kour, Claudia Espinosa‐García, Wooyoung Eric Jang, Upasna Srivastava, Bernard Mulvey, Margaret M. Tish, Ronit Witztum et al. · 2026 · Molecular Psychiatry
- Evolving alterations of structural organization and functional connectivity in feedforward neural networks after induced P301L tau mutationJanelle S. Weir, Katrine Sjaastad Hanssen, Nicolai Winter‐Hjelm, Axel Sandvig, Ioanna Sandvig · 2024 · European Journal of Neuroscience
- Tauopathy severely disrupts homeostatic set-points in emergent neural dynamics but not in the activity of individual neuronsJames N. McGregor, Clayton A. Farris, Sahara Ensley, Aidan M Schneider, Chao Wang, Yuqi Liu, Jianhong Tu, Halla Elmore, Keenan D. Ronayne, Ralf Weßel et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Pathological tau alters head direction signaling and induces spatial disorientationShan Jiang, Sara Hijazi, Barbara Sárkány, Verena G. Gautsch, Patrick A. LaChance, Michael Erik Hasselmo, David M. Bannerman, Tim J. Viney · 2025 · Cell Reports
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- A new hope: locus coeruleus-norepinephrine system at the nexus of neuropsychiatric symptomsAnu Korukonda, David Weinshenker · 2026 · Molecular Psychiatry
- Detection of Tau-PET Positivity in Clinically Diagnosed Mild Cognitive Impairment with Multidimensional FeaturesBingyu Li, Alzheimer’s Disease Neuroimaging Initiative, Kening Shi, Chao Ren, Min Kong, Maowen Ba · 2023 · Journal of Alzheimer s Disease
- Restoring neuronal excitability and spatial memory through inhibiting amyloid-β-induced hyperactive NF-κB in a rat model of Alzheimer’s diseaseZahra Soleimani, Shima Davoudi, Fatemeh Saffarzadeh, Gila Behzadi, Mehdi Mehdizadeh, Mona Rahdar, Narges Hosseinmardi, Mahyar Janahmadi, Mohammad Javad Eslamizade · 2025 · Brain Research
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- Reducing Tau Ameliorates Behavioural and Transcriptional Deficits in a Novel Model of Alzheimer's DiseaseEleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly M. Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Louise Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad et al. · 2018 · SSRN Electronic Journal
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- Hyperphosphorylated Tau Induces Cortical Hypoexcitability in Transgenic Mouse Models: A Meta-AnalysisCarlos Antonio García-Carlos, Gustavo Basurto‐Islas, George L. Perry, César Campos-Ramírez, Siddhartha Mondragón‐Rodríguez · 2025 · Journal of Integrative Neuroscience
- Selective vulnerability of human synapses to soluble tau oligomersShrinath Kadamangudi, Laura Sánchez-Sánchez, Rakez Kayed, Agenor Limón, Giulio Taglialatela · 2026 · Journal of Alzheimer s Disease
- GV1001 reduces pathological 4R tau and functional deficits in models relevant to progressive supranuclear palsyKyu-Beom Jang, Daewon Kang, Myung-Hoon Lee, Nataliia Lukianenko, Yun Kyung Kim, Sungsu Lim, Sangjae Kim, Hyun Jin Cho · 2026 · Scientific Reports
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- Medium spiny neurons activity reveals the discrete segregation of mouse dorsal striatumJ. Alegre-Cortés, M. Sáez, R. Montanari, R. Reig · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
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- Tau drives cell specific functional isolation of the hippocampal formationTheodore J. Zwang, Jasen Zhang, Rudy Gelb-Bicknell, Nina Wolf, Viktor Chanchykov, Haoyang Zhu, Ergina Agastra, Ava Devine, Andrew J. Holbrook, Rachel E. Bennett et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Synapse loss in Progressive Supranuclear Palsy post-mortem reflects clinical and pathological disease severity and 11 C-UCB-J PET in vivoGeorge Nolan, Negin Holland, Shangqing W. Yang, Ginevra Matilde Dall‘O’, Qiyuan Chen, Kieren Simon James Allinson, George Savulich, Kristy Halliday, Michelle Naessens, Young T. Hong et al. · 2026 · medRxiv
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- Additional file 2 of Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathyHaihan Jiao, Downie, Laura E., Xin Huang, Wu, Mengliang, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson, Holly Rose Chinnery · 2020 · Figshare
- Additional file 1 of Novel alterations in corneal neuroimmune phenotypes in mice with central nervous system tauopathyHaihan Jiao, Downie, Laura E., Xin Huang, Wu, Mengliang, Sara Oberrauch, Ryan J. Keenan, Laura H. Jacobson, Holly Rose Chinnery · 2020 · Figshare
- Additional file 1 of In vivo tau pathology is associated with synaptic loss and altered synaptic functionEmma M. Coomans, Deborah N. Schoonhoven, Hayel Tuncel, Sander C.J. Verfaillie, Emma E. Wolters, Ronald Boellaard, Rik Ossenkoppele, Anouk den Braber, Wiep Scheper, Patrick R. Schober et al. · 2021 · Figshare
- Additional file 1 of Tau-related grey matter network breakdown across the Alzheimer’s disease continuumWiesje Pelkmans, Rik Ossenkoppele, Ellen Dicks, Strandberg, Olof, Frederik Barkhof, Betty Marije Tijms, Pereira, Joana B., Oskar Hansson · 2021 · Figshare
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