Biochemical Computation for Spine Structural Plasticity
Cited by (198)
Items 101–198 of 198
- Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separationMaria Vistrup-Parry, Xudong Chen, Thea L. Johansen, Sofie Bach, Sara Charlotte Buch-Larsen, Christian R. O. Bartling, Chenxue Ma, Louise S. Clemmensen, Michael Lund Nielsen, Mingjie Zhang et al. · 2021 · iScience
- Dendritic spine morphology regulates calcium-dependent synaptic weight changeMiriam K. Bell, M. Holst, Christopher T. Lee, Padmini Rangamani · 2022 · The Journal of General Physiology
- Genome editing in the mammalian brain using the CRISPR–Cas systemJun Nishiyama · 2018 · Neuroscience Research
- The role of molecular diffusion within dendritic spines in synaptic functionKazuki Obashi, Justin W. Taraska, Shigeo Okabe · 2021 · The Journal of General Physiology
- Skewed distribution of spines is independent of presynaptic transmitter release and synaptic plasticity, and emerges early during adult neurogenesisNina Rößler, Tassilo Jungenitz, Albrecht Sigler, Alexander Bird, Martin Mittag, Jeong Seop Rhee, Thomas Deller, Hermann Cuntz, Nils Brose, Stephan Wolfgang Schwarzacher et al. · 2023 · Open Biology
- Single Synapse LTP: A Matter of Context?Dennis L.H. Kruijssen, Corette J. Wierenga · 2019 · Frontiers in Cellular Neuroscience
- Selective activation of BK channels in small‐headed dendritic spines suppresses excitatory postsynaptic potentialsSabrina Tazerart, Maxime G. Blanchard, Soledad Miranda‐Rottmann, Diana E. Mitchell, Bruno Navea Pina, Connon I. Thomas, Naomi Kamasawa, Roberto Araya · 2022 · The Journal of Physiology
- Axonal CB1 Receptors Mediate Inhibitory Bouton Formation via cAMP Increase and PKAJian Liang, Dennis L.H. Kruijssen, Aniek C. J. Verschuuren, Bas J. B. Voesenek, Feline F. W. Benavides, Maria Sáez González, Marvin Ruiter, Corette J. Wierenga · 2021 · Journal of Neuroscience
- Apolipoprotein E in Alzheimer’s Disease: Focus on Synaptic Function and Therapeutic StrategyLongjie Qu, Shuai Xu, Zhen Lan, Shuang Fang, Yun Xu, Xiaolei Zhu · 2024 · Molecular Neurobiology
- A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowthAndrew M. Hamilton, Jason T. Lambert, Laxmi Kumar Parajuli, Oscar Vivas, D.K. Park, Ivar S. Stein, Jennifer N. Jahncke, Michael E. Greenberg, Seth S. Margolis, Karen Zito · 2017 · Molecular and Cellular Neuroscience
- Developmental regulation of hippocampal long-term depression by cofilin-mediated actin reorganizationFeng Cao, Zikai Zhou, Xingxiu Pan, Celeste Leung, Wei Xie, Graham L. Collingridge, Zhengping Jia · 2016 · Neuropharmacology
- Development of Targeted Mass Spectrometry-Based Approaches for Quantitation of Proteins Enriched in the Postsynaptic Density (PSD)Rashaun S. Wilson, Navin Rauniyar, Fumika Sakaue, TuKiet T. Lam, Kenneth R. Williams, Angus Clark Nairn · 2019 · Proteomes
- Shootin1a-mediated actin-adhesion coupling generates force to trigger structural plasticity of dendritic spinesRia Fajarwati Kastian, Takunori Minegishi, Kentarou Baba, Takeo Saneyoshi, Hiroko Katsuno‐Kambe, Singh Saranpal, Yasunori Hayashi, Naoyuki Inagaki · 2021 · Cell Reports
- PSD-Zip70 Deficiency Causes Prefrontal Hypofunction Associated with Glutamatergic Synapse Maturation Defects by Dysregulation of Rap2 ActivityTaira Mayanagi, Hiroki Yasuda, Kenji Sobue · 2015 · Journal of Neuroscience
- Strategies to dissect microglia-synaptic interactions during aging and in Alzheimer's diseaseSarah E. Heuer, Erik B. Bloss, Gareth R. Howell · 2024 · Neuropharmacology
- Regulation of filial imprinting and structural plasticity by mTORC1 in newborn chickensGervasio Batista, Jennifer L. Johnson, Elena Nicole Dominguez, Mauro Costa‐Mattioli, José Luis Peña · 2018 · Scientific Reports
- Dendritic, delayed, and stochastic CaMKII activation underlies behavioral time scale plasticity in CA1 synapsesAnant Jain, Yoshihisa Nakahata, Tetsuya Watabe, Polina Rusina, Kelly South, Kengo Adachi, Long Yan, Noriko Simorowski, Hiro Furukawa, Ryohei Yasuda · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Neuronal Synapses: Microscale Signal Processing Machineries Formed by Phase Separation?Zhe Feng, Menglong Zeng, Xudong Chen, Mingjie Zhang · 2018 · Biochemistry
- Principle and Application of Fluorescence Lifetime Imaging for NeuroscienceRyohei Yasuda · 2019 · Elsevier eBooks
- L-type Ca 2+ channel activation of STIM1–Orai1 signaling remodels the dendritic spine ER to maintain long-term structural plasticityPhilip J. Dittmer, Mark L. Dell’Acqua · 2024 · Proceedings of the National Academy of Sciences
- Treadmill exercise ameliorates hippocampal synaptic injury and recognition memory deficits by TREM2 in AD rat modelLinlin Zhang, Yanzhong Liu, Xin Wang, Hao Wu, Jiahui Xie, Yiping Liu · 2025 · Brain Research Bulletin
- Imaging intracellular protein interactions/activity in neurons using 2-photon fluorescence lifetime imaging microscopyHiromi H. Ueda, Yutaro Nagasawa, Hideji Murakoshi · 2021 · Neuroscience Research
- RGS14 expression in CA2 hippocampus, amygdala, and basal ganglia: Implications for human brain physiology and diseaseCarolina Montañez‐Miranda, Sara N. Bramlett, John R. Hepler · 2022 · Hippocampus
- Mice deficient in synaptic protease neurotrypsin show impaired spaced long-term potentiation and blunted learning-induced modulation of dendritic spinesMaura Ferrer-Ferrer, Shaobo Jia, Rahul Kaushik, Jenny Schneeberg, Izabela Figiel, Stepan E. Aleshin, Andrey Alexandrovich Mironov, Motahareh Safari, Renato Frischknecht, Jakub Włodarczyk et al. · 2023 · Cellular and Molecular Life Sciences
- Probing Single Synapses via the Photolytic Release of NeurotransmittersDiana E. Mitchell, Éric Martineau, Sabrina Tazerart, Roberto Araya · 2019 · Frontiers in Synaptic Neuroscience
- Rabphilin-3A Drives Structural Modifications of Dendritic Spines Induced by Long-Term PotentiationLuca Franchini, Jennifer Stanic, Marta Barzasi, Elisa Zianni, Daniela Mauceri, Mónica Di Luca, Fabrizio Gardoni · 2022 · Cells
- Methodological approaches to understand the molecular mechanism of structural plasticity of dendritic spinesTakayasu Mikuni, Motokazu Uchigashima · 2020 · European Journal of Neuroscience
- Imaging neuronal structure dynamics using 2‐photon super‐resolution patterned excitation reconstruction microscopyBen E. Urban, Lei Xiao, Biqin Dong, Siyu Chen, Yevgenia Kozorovitskiy, Hao F. Zhang · 2017 · Journal of Biophotonics
- MMP-9 in Control of Synaptic Plasticity: a Subjective AccountLeszek Kaczmarek · 2016 · Russian Agency for Digital Standardization
- Perivascular space diffusivity and brain microstructural measures are associated with circadian time and sleep qualityKristoffer Brendstrup‐Brix, Sara Marie Ulv Larsen, Hong‐Hsi Lee, Gitte M. Knudsen · 2024 · Journal of Sleep Research
- Inhibitory postsynaptic density from the lens of phase separationGuanhua Bai, Mingjie Zhang · 2022 · Oxford Open Neuroscience
- Shedding light on learning and memory: optical interrogation of the synaptic circuitryJu Lu, Yi Zuo · 2020 · Current Opinion in Neurobiology
- PCC-0105002, a novel small molecule inhibitor of PSD95-nNOS protein-protein interactions, attenuates neuropathic pain and corrects motor disorder associated with neuropathic pain modelZhihong Sun, Ping Meng, Chunyu Su, Shengmin Ji, Yonglin Gao, Hongbo Wang, Jingwei Tian, Chunmei Li · 2021 · Toxicology and Applied Pharmacology
- Hippocampal Dendritic Spines Are Segregated Depending on Their Actin PolymerizationNuria Domıńguez-Iturza, Marı́a Calvo, Marion Benoist, Jose Antonio Esteban, Miguel Morales · 2016 · Neural Plasticity
- Circadian Changes of Dendritic Spine Geometry in Mouse Barrel CortexMałgorzata Jasińska, Olga Woźnicka, Ewa Jasek-Gajda, GRZEGORZ J. LIS, Elżbieta Pyza, Jan A. Litwin · 2020 · Frontiers in Neuroscience
- Optogenetic Imaging of Protein Activity Using Two-Photon Fluorescence Lifetime Imaging MicroscopyHideji Murakoshi · 2021 · Advances in experimental medicine and biology
- Dendritic effects of genetically encoded actin-labeling probes in cultured hippocampal neuronsAttila Ignácz, Domonkos Nagy-Herczeg, Angelika Haußer, Katalin Schlett · 2023 · Molecular Biology of the Cell
- Correlative Ultrastructural Analysis of Functionally Modulated Synapses Using Automatic Tape-Collecting Ultramicrotome - SEM Array TomographyNaomi Kamasawa, Ye Sun, Takayasu Mikuni, Debbie Guerrero‐Given, Ryohei Yasuda · 2015 · Microscopy and Microanalysis
- Protein drift-diffusion dynamics and phase separation in curved cell membranes and dendritic spines: Hybrid discrete-continuum methodsPatrick D. Tran, Thomas A. Blanpied, Paul J. Atzberger · 2022 · Physical review. E
- Acute drug-induced spine changes in the nucleus accumbens are dependent on β-adducinOlivia Engmann, Albert Giralt, Jean‐Antoine Girault · 2016 · Neuropharmacology
- Synapses drive local mitochondrial ATP synthesis to fuel plasticityIlika Ghosh, Ruolin Fan, Monil Shah, Ojasee Bapat, Vidhya Rangaraju · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Phase separation instead of binding strength determines target specificities of MAGUKsYan Chen, Chenxue Ma, Zeyu Shen, Shiwen Chen, Shihan Zhu, Bowen Jia, Shangyu Dang, Mingjie Zhang · 2025 · Nature Chemical Biology
- The spiny relationship between parallel fibers, climbing fibers, and Purkinje cellsStefano Masoli, Martina Francesca Rizza, Francesco Domenico Moccia, Egidio Ugo D'Angelo · 2025 · Frontiers in Physiology
- Imaging Neuronal Signal Transduction Using Multiphoton FRET-FLIMPaul R. Evans, Long Yan, Ryohei Yasuda · 2019 · Neuromethods
- Fhod3 Controls the Dendritic Spine Morphology of Specific Subpopulations of Pyramidal Neurons in the Mouse Cerebral CortexHikmawan Wahyu Sulistomo, Takayuki Nemoto, Yohko Kage, Hajime Fujii, Taku Uchida, Kogo Takamiya, Hideki Sumimoto, Hiroaki Kataoka, Haruhiko Bito, Ryu Takeya · 2020 · Cerebral Cortex
- Electrophysiology of Dendritic Spines: Information Processing, Dynamic Compartmentalization, and Synaptic PlasticityJoseane Righes Marafiga, María Elisa Calcagnotto · 2023 · Advances in neurobiology
- Synaptic pruning following NMDAR-dependent LTD preferentially affects isolated synapsesCamus, Côme, Leval, Léa, Villicana-Munoz, Viviana, Jelinkova, Sarka, Compans, Benjamin, Gambino, Frédéric, Herzog, Etienne, Choquet, Daniel, Hosy, Eric · 2025 · iScience
- Conditions for Synaptic Specificity during the Maintenance Phase of Synaptic PlasticityMarco A. Huertas, Adam J. H. Newton, Robert A. McDougal, Todd Charlton Sacktor, Harel Z. Shouval · 2022 · eNeuro
- The ameliorating effect of exercise on long-term memory impairment and dendritic retraction via the mild activation of AMP-activated protein kinase in chronically stressed hippocampal CA1 neuronsYea‐Hyun Leem, Hyukki Chang · 2018 · Physical Activity and Nutrition
- Cellular intelligence: dynamic specialization through non-equilibrium multi-scale compartmentalizationRémy Tuyéras, Leandro Z. Agudelo, Soumya P. Ram, Anjanet R. Loon, Burak Kutlu, Kevin L. Grove, M Kellis · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- SUMOylation balance: a key determinant in synapse physiologyAlessia Bertozzi, Walter Toscanelli, Giuditta Castellitto, Claudio Grassi, Claudia Colussi · 2025 · Frontiers in Physiology
- Two-factor synaptic consolidation reconciles robustness with pruning and homeostatic scalingGeorgios Iatropoulos, Wulfram Gerstner B, Johanni Brea · 2025 · Proceedings of the National Academy of Sciences
- Autoregulation of switching behavior by cellular compartment sizeMónika Józsa, Tihol Ivanov Donchev, Rodolphe J. Sepulchre, Timothy O’Leary · 2022 · Proceedings of the National Academy of Sciences
- Maintenance of Lognormal‐Like Skewed Dendritic Spine Size Distributions in Dentate Granule Cells of TNF, TNF‐R1, TNF‐R2, and TNF‐R1/2‐Deficient MiceNina Rößler, Dinko Smilović, Mario Vukšić, Peter Jedlička, Thomas Deller · 2024 · The Journal of Comparative Neurology
- Determinants of affinity, specificity, and phase separation in a supramodule from Post-synaptic density protein 95Louise Vagner Laursen, Raviteja Inturi, Søren Østergaard, Per Jemth · 2022 · iScience
- Cdc42 signaling regulated by dopamine D2 receptor correlatively links specific brain regions of hippocampus to cocaine addictionJuan Li, Yue Hui Wu, Tao Xue, Jing He, Lei Zhang, Ying Liu, Jinlan Zhao, Zhenzhong Chen, Minjuan Xie, Bin Xiao et al. · 2022 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- Piconewton‐Scale Analysis of Ras‐BRaf Signal Transduction with Single‐Molecule Force SpectroscopyChae‐Seok Lim, Cheng Wen, Yanghui Sheng, Guangfu Wang, Zhuan Zhou, Shi‐Qiang Wang, Huaye Zhang, Anpei Ye, Jie Zhu · 2017 · Small
- A spike-timing-dependent plasticity rule for single, clustered and distributed dendritic spinesSabrina Tazerart, Diana E. Mitchell, Soledad Miranda‐Rottmann, Roberto Araya · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problemZahra Khodadadi, Daniel Trpevski, Robert Lindroos, Jeanette Hellgren Kotaleski · 2025 · eLife
- The role of astrocytic ephrins and Eph receptors in astrocyte function, synaptic plasticity, and memory formationRaphael Lamprecht · 2026 · Neuroscience & Biobehavioral Reviews
- Updates on Endoplasmic ReticulumGaia Favero · 2022 · Biochemistry
- H-Ras induces exuberant de novo dendritic protrusion growth in mature neurons regardless of cell typeSarah Krüssel, Ishana Deb, Seungkyu Son, Gabrielle Ewall, Minhyeok Chang, Hey‐Kyoung Lee, Won Do Heo, Hyung‐Bae Kwon · 2024 · iScience
- Extracellular Remodeling by Lysosomes: An Inside-Out Mechanism of Spine PlasticityPaul R. Evans, Ryohei Yasuda · 2017 · Neuron
- Mitochondria-Endoplasmic Reticulum Interaction in Central NeuronsLiliia Kushnireva, Eduard Korkotian · 2022 · Biochemistry
- Correlative Ultrastructural Analysis of Functionally Modulated Synapses Using Automated Tape-Collecting Ultramicrotome and SEM Array TomographyYe Sun, Connon I. Thomas, Takayasu Mikuni, Debbie Guerrero‐Given, Ryohei Yasuda, Naomi Kamasawa · 2020 · Neuromethods
- Two-factor synaptic consolidation reconciles robust memory with pruning and homeostatic scalingGeorgios Iatropoulos, Wulfram Gerstner, Johanni Brea · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Calcium-based input timing learningShirin Shafiee, Sebastian Schmitt, Christian Tetzlaff · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problemZahra Khodadadi, Daniel Trpevski, Robert Lindroos, Jeanette Hellgren Kotaleski · 2024 · eLife
- Dendritic heterosynaptic plasticity arises from calcium-based input learningShirin Shafiee, Sebastian Schmitt, Christian Tetzlaff · 2026 · Communications Biology
- Seasonal comparison of the neuromuscular junction morphology of Bufo marinusDengyun Ge, Peter G. Noakes, Nickolas A. Lavidis · 2019 · The Journal of Comparative Neurology
- Dendritic Spine Plasticity and Memory FormationMartine Ammassari‐Teule, Menahem Segal · 2017 · Elsevier eBooks
- Site-specific phosphorylation of PSD-95 dynamically regulates the post-synaptic density as observed by phase separationMaria Vistrup-Parry, Xudong Chen, Thea L. Johansen, Sofie Bach, Sara Charlotte Buch-Larsen, Christian R. O. Bartling, Chenxue Ma, Louise S. Clemmensen, Michael Lund Nielsen, Mingjie Zhang et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Comparative analysis of actin visualization by genetically encoded probes in cultured neuronsAttila Ignácz, Domonkos Nagy-Herczeg, Angelika Haußer, Katalin Schlett · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Detailed dendritic excitatory/inhibitory balance through heterosynapticNaoki Hiratani, Tomoki Fukai · 2016
- NOVEL APPROACHES TO THE STUDY OF SYNAPTIC PLASTICITY IN THE RAT HIPPOCAMPUSBorbala Podor · 2017 · DalSpace (Dalhousie University)
- Analysis of TrkB Receptor Activity Using FRET SensorsCharles E. Hall, James O McNamara, Ryohei Yasuda · 2018 · Neuromethods
- Activity-based automatic ROI generation (AARG) analysis of dendritic spine calcium transients reveals distance-dependent activity of voltage-gated calcium channelsCharlie J. Gilbride · 2018
- WITHDRAWN: PCC-0105002, a novel small molecule inhibitor of PSD95-nNOS protein-protein interactions, attenuates neuropathic pain and corrects motor coordination-associated side effects in neuropathic pain modelChunmei Li, Chunyu Su, Zhezhe Wang, Rui Han, Yu Wang, Hongbo Wang, Jingwei Tian, Yonglin Gao · 2020 · Toxicology and Applied Pharmacology · Retracted
- Exciting inhibition: Local regulation of synapse formation and plasticityDennis L.H. Kruijssen · 2020 · Utrecht University Repository (Utrecht University)
- Dendritic biophysics and evolutionLou Beaulieu-Laroche · 2020 · DSpace@MIT (Massachusetts Institute of Technology)
- To be or not to be?Liang, Jian · 2022 · Utrecht University Repository (Utrecht University)
- Faculty Opinions recommendation of Dendritic spine elimination: molecular mechanisms and implications.Masanobu Kano, Takaki Watanabe · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiationJie Wang, Jun Nishiyama, Paula Parra-Bueno, Elwy Okaz, Goksu Oz, Xiaodan Liu, Tetsuya Watabe, Irena Suponitsky-Kroyter, Timothy E. McGraw, Erzsebet M. Szatmari et al. · 2025 · eLife
- Methods to Visualize Structural and Functional Changes at SynapsesThomas M. Newpher · 2022 · Journal of Visualized Experiments
- Disinhibition of Rab10 gates AMPAR insertion and spine enlargement during long-term potentiationJie Wang, Jun Nishiyama, Paula Parra-Bueno, Elwy Okaz, Goksu Oz, Xiaodan Liu, Irena Suponitsky-Kroyter, Timothy E. McGraw, Erzsebet M. Szatmari, Ryohei Yasuda · 2022 · Research Square
- Exuberant de novo dendritic spine growth in mature neuronsSarah Krüssel, Ishana Deb, Seungkyu Son, Gabrielle Ewall, Minhyeok Chang, Hey‐Kyoung Lee, Won Do Heo, Hyung‐Bae Kwon · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiationJie Wang, Jun Nishiyama, Paula Parra-Bueno, Elwy Okaz, Goksu Oz, Xiaodan Liu, Tetsuya Watabe, Irena Suponitsky-Kroyter, Timothy E. McGraw, Erzsebet M. Szatmari et al. · 2024 · eLife
- Rab10 inactivation promotes AMPAR insertion and spine enlargement during long-term potentiationJie Wang, Jun Nishiyama, Paula Parra-Bueno, Elwy Okaz, Goksu Oz, Xiaodan Liu, Tetsuya Watabe, Irena Suponitsky-Kroyter, Timothy E. McGraw, Erzsebet M. Szatmari et al. · 2024 · eLife
- The amygdala and fear memoryRaphael Lamprecht · 2024 · Elsevier eBooks
- Rab10 inactivation promotes AMPAR trafficking and spine enlargement during long-term potentiationJie Wang, Jun Nishiyama, Paula Parra-Bueno, Elwy Okaz, Goksu Oz, Xiaodan Liu, Tetsuya Watabe, Irena Suponitsky-Kroyter, Timothy E. McGraw, Erzsebet M. Szatmari et al. · 2025 · eLife
- Single-molecule imaging reveals activity-dependent regulation of Camk2a mRNAs at dendritic spinesDong-Woo Hwang, Karthik Krishnamurthy, Arya Nagare, Robert H. Singer, Sulagna Das · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Local, calcium- and reward-based synaptic learning rule that enhances dendritic nonlinearities can solve the nonlinear feature binding problemZahra Khodadadi, Daniel Trpevski, Robert Lindroos, Jeanette Hellgren Kotaleski · 2025 · eLife
- Learning sculpts orthogonal task manifolds for continual skill learning in recurrent networksZihan Liu, Anno Christopher Kurth, Yuma Osako, Toshitake Asabuki · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Altérations des synapses et des corps cellulaires neuronaux chez les souris APPxPS1-KI et dans la Maladie d'AlzheimerAlexandre Androuin · 2018 · theses.fr (ABES)
- Computational modeling of calcium diffusion reveals nanoscale biophysics in neuronal spinesKanishka Basnayake · 2020 · theses.fr (ABES)
- Interaction between synaptic and structural plasticityCôme Camus · 2021 · theses.fr (ABES)
- Linking functional and structural dendritic spine remodeling during fear learning and extinction in vivoX L Li, Qiyu Zheng, Kim Hoi Kin Wong, Kenneth K. Y. Wong, Cora Sau Wan Lai · 2026 · Science Advances
- The PSD-95 interactome of hippocampal synapses potentiated in response to an in vivo learning taskAjesh Jacob, Mariachiara Di Caprio, Ivan Arisi, Francesco Gobbo, Francesca Chiara Latini, Andrea Faraone, Lorena Zentilin, Ivonne Heinze, Silvia Marinelli, Alessandro Ori et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)