Down Syndrome Developmental Brain Transcriptome Reveals Defective Oligodendrocyte Differentiation and Myelination
Olmos-Serrano, Jose Luis, Kang, Hyo Jung, Tyler, William A., Silbereis, John C., Cheng, Feng, Zhu, Ying, Pletikos, Mihovil, Jankovic-Rapan, Lucija +9 more·2016·Neuron
Cited by (238)
Items 201–238 of 238
- Expresión de genes asociados a discapacidad mental en cerebros de pacientes con síndrome de DownMeliza Santiago Ospina, Alejandra Rodríguez, Julio César Montoya · 2016
- The Altered Roles of Glia in Neurodevelopmental DisordersRachel L. Doser · 2017 · UA Campus Repository (The University of Arizona)
- A New Approach to The Pathogenesis of Down Syndrome: An Integrated Quantitative Neuro-Transcriptome Analysis of Several Brain Areas in Human Trisomy 21.Alejandra Rodríguez-Ortiz, Julio César Montoya Villegas, Adalberto Sánchez, José María Satizábal Soto, Yecid Mina-Paz, Felipe García‐Vallejo · 2021 · Research Square
- The dark side of the brain, myelinating glia in central and peripheral nervous systemsRoman Chrast, Gonçalo Castelo‐Branco · 2021 · Seminars in Cell and Developmental Biology
- Transcriptômica de autismo e deficiências intelectuais: uma abordagem de biologia de sistemas para identificar especificidades e convergênciasBruna Garbes Gonçalves Pinto · 2021 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
- Identificação de modelos celulares de fácil obtenção com preservação de módulos de co-expressão desregulados em transtorno do espectro autista e deficiência intelectualCamily Rodrigues · 2021
- Faculty Opinions recommendation of Restoration of brain circulation and cellular functions hours post-mortem.Laurent Villard · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Faculty Opinions recommendation of Multimodal Single-Cell Analysis Reveals Physiological Maturation in the Developing Human Neocortex.Vı́ctor Borrell · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Gene-dosage imbalance and altered neurogenesis in Down syndromeBani Bandana Ganguly · 2022 · Elsevier eBooks
- Development of Cortical Neuron Heterogeneity and Impact of Neurodevelopmental DisordersZhen Li, William A. Tylerand, Tarik F. Haydar · 2023
- Developmental and Evolutionary Origins of Cortical Projection Neuron Identity and ConnectivityNavjot Kaur, Rothem Kovner, Kevin T. Gobeske, Nenad Šestan · 2023 · Wiley eBooks
- Pleiotropic effects of trisomy and pharmacologic modulation on structural, functional, molecular, and genetic systems in a Down syndrome mouse modelSergi Llambrich, Birger Tielemans, Ellen Saliën, Marta Atzori, Kaat Wouters, Vicky Van Bulck, Mark Platt, Laure Vanherp, Nuria Gallego Fernandez, Laura Grau de la Fuente et al. · 2024 · eLife
- Copy number variations of proteins associated with neurodegenerative diseases and rare neurological disordersZhangzhong Yang, Peng Lei · 2024 · Scientia Sinica Vitae
- Human Models of Down SyndromeMegan Jandy, Hao Hu, Yan Liu, Anita Bhattacharyya · 2025 · Springer eBooks
- Down Syndrome: Progress in Defining Pathogenesis and Treatments for Neurodevelopmental Deficits and Alzheimer’s DiseaseRenata Bartesaghi, Xu‐Qiao Chen, Aaron D. Johnstone, Utpal Das, William Cary Mobley · 2025 · Springer eBooks
- Genetic and Molecular Insights into the Links Between Heat Stroke, Alzheimer’s Disease, and Down Syndrome: A Mini-ReviewHisahide Nishio, Hirokuni Negishi, Hiroyuki Awano, Jumpei Oba · 2025 · Genes
- Functional development of midbrain and pons during human gestation and electrophysiological markers for DS interventionYongkang Wu, Yingmei Fu, Hao Yang Peng, Yanni Chen, Wang Fanglin, Jian Wang, Jinli Ou, Yigang Dong, Qingmiao Hu, Yan Cui et al. · 2025 · Journal of Advanced Research
- The endocannabinoid system in intellectual disabilityAnna Vázquez-Oliver, Lucía de los Reyes‐Ramírez, Lorena Galera-López, Andrés Ozaita · 2025 · Handbook of behavioral neuroscience
- Additional file 1 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Rossella Zenatelli, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Additional file 12 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Rossella Zenatelli, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Catapano, Francesca, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Additional file 6 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Rossella Zenatelli, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Additional file 3 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Rossella Zenatelli, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Additional file 4 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Zenatelli, Rossella, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Additional file 2 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Zenatelli, Rossella, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Francesca Catapano, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Additional file 5 of The transcriptome profile of human trisomy 21 blood cellsFrancesca Antonaros, Rossella Zenatelli, Guerri, Giulia, Bertelli, Matteo, Locatelli, Chiara, Beatrice Vione, Catapano, Francesca, Alice Gori, Lorenza Vitale, Maria Chiara Pelleri et al. · 2021 · Figshare
- Single-cell atlas of the fetal Down syndrome cortex uncovers chromosome 21 regulators of intellectual disability gene networksMichael Lattke, Wee Leng Tan, Salil Kalarikkal Sukumaran, Kagistia Hana Utami, Marcos Sintes, Srinivasan Sakthivel, Jonathan Tan, Auriel Theodora Jacobea Lim, Vibhavari Aysha Bansal, Katerina Rekopoulou et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Genome-wide cell type-specific and sex-specific transcriptional dysregulation in the islet of Langerhans underlies islet dysfunction in Down syndrome-related diabetesCyrus R. Sethna, Maria Del Carmen Mendoza Niemes, Bayley J. Waters, Matthew R. Wagner, Jacob Smith, Sutichot D. Nimkulrat, Julia Lemanski, Nicolas G Pintozzi, Valentina Lo Sardo, Barak Blum · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Trisomy 21 Drives ADARB1 Overexpression and Premature RNA Recoding in the Developing Fetal BrainMichael S. Breen, Andy Yang, Xuran Wang, Miguel Rodríguez de los Santos, Ran TAO, Daniel R. Weinberger, Joel E. Kleinman, Kalina Yonkova Mihova, Gergana S. Stancheva, Sylvia Savova et al. · 2026 · Nature Communications
- Multi-omics data integration and interactive visual data mining to explore mitochondrial dynamicsFabio Marchianò · 2022 · theses.fr (ABES)
- Fonctions de PAK1 dans la régulation du cytosquelette d’actine : implication dans la myélinisation du système nerveux centralLucas Baudouin · 2021 · theses.fr (ABES)
- Étude du neurodéveloppement et de l'infertilité masculine chez différents modèles murins de Trisomie 21Rodolphe Dard · 2024
- Early dynamics of the genome in Down syndromeTarik F. Haydar, Zhen Li · 2026 · Science
- RegRegSEA: a web server for regulatory region set enrichment analysis of epigenomic dataTobias William Wolff, Friederike Grandke, MISBAH SAYEEDA, Pascal Hirsch, Matthias Flotho, Andreas Keller · 2026 · Nucleic Acids Research
- Multiomics and proteomic insights into Alzheimer’s disease biology in Down syndromeMitchell Martá-Ariza, T R Wisniewski · 2026 · Expert Review of Neurotherapeutics
- Oligodendrocyte Enriched Brain Organoids Reveal Impaired Oligodendroglial Maturation and Altered Neural Network Activity in Down SyndromeMarta Boira Marti, Sean D. Morrison, Selin Pars, Bahaa Al-mhanawi, Peter G. Noakes, Ernst Jurgen Wolvetang, Mohammed R. Shaker · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Epilepsy Mechanisms in Down Syndrome: Genetic and Pathophysiological Perspectives Across the LifespanCarl E. Stafstrom, Li‐Rong Shao · 2026 · Journal of Clinical Medicine
- A pattern to rule them all: tracing a human brain map of molecular aspects shared by Alzheimer’s disease and dementia with Lewy bodiesRiccardo Rocco Ferrari, Maria Garofalo, Rosalinda Di Gerlando, Elisa Pellegrini, Francesca Dragoni, Bartolo Rizzo, Michele Rossi, Chiara Calatozzolo, Antonio Guaita, Annalisa Davin et al. · 2026 · GeroScience
- Human-induced pluripotent stem cell-derived neural cells to model epigenetic regulations in the nervous system and brain disorders in vitroYAN HONG, Guo-li Ming, HONGJUN SONG · 2026 · Handbook of clinical neurology