Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells

Sloan, Steven A., Darmanis, Spyros, Huber, Nina, Khan, Themasap A., Birey, Fikri, Caneda, Christine, Reimer, Richard, Quake, Stephen R. +2 more·2017·Neuron

Cited by (596)

Items 201–300 of 596

  1. Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model
    Song, Ren, Pekrun, Katja, Khan, Themasap A., Zhang, Feijie, Paşca, Sergiu P., Kay, Mark A. · 2022 · Molecular Therapy - Methods & Clinical Development
  2. Human Striatal Organoids Derived from Pluripotent Stem Cells Recapitulate Striatal Development and Compartments
    Xinyu Chen, Hexige Saiyin, Yang Liu, Yuqi Wang, Xuan Li, Rong Ji, Lixiang Ma · 2021 · PLoS Biology
  3. The NLRP3 Inflammasome in Neurodegenerative Disorders: Insights from Epileptic Models
    Laura Palumbo, Marianna Carinci, Annunziata Guarino, Laila Asth, Silvia Zucchini, Sonia Missiroli, Alessandro Rimessi, Paolo Pinton, Carlotta Giorgi · 2023 · Biomedicines
  4. Semaglutide ameliorates Alzheimer's disease and restores oxytocin in APP/PS1 mice and human brain organoid models
    Zhang, Yinbing, Tang, Cheng, He, Yao, Zhang, Yingqian, Li, Qinxi, Zhang, Ting, Zhao, Bangcheng, Tong, Aiping, Zhong, Qixing, Zhong, Zhihui · 2024 · Biomedicine & Pharmacotherapy
  5. Exploring human brain development and disease using assembloids
    Sih‐Rong Wu, Tomasz Jan Nowakowski · 2025 · Neuron
  6. Pharmacogenomics in drug-induced cardiotoxicity: Current status and the future
    Moyun Li, Peng Li-ming, Xiaoping Chen · 2022 · Frontiers in Cardiovascular Medicine
  7. A defined roadmap of radial glia and astrocyte differentiation from human pluripotent stem cells
    Vukasin M. Jovanovic, Claire Weber, Jaroslav Slamecka, Seungmi Ryu, Pei‐Hsuan Chu, Chaitali Sen, Jason M. Inman, Juliana Ferreira de Sousa, Elena S. Barnaeva, Marissa B. Hirst et al. · 2023 · Stem Cell Reports
  8. Glial regulation of synapse maturation and stabilization in the developing nervous system
    Marion R. Van Horn, Edward S. Ruthazer · 2018 · Current Opinion in Neurobiology
  9. Wnt-Notch Signaling Interactions During Neural and Astroglial Patterning of Human Stem Cells
    Julie Bejoy, Brent M. Bijonowski, Mark Marzano, Richard Jeske, Teng Ma, Yan Li · 2019 · Tissue Engineering Part A
  10. Brain organoids: Human 3D models to investigate neuronal circuits assembly, function and dysfunction
    Monica Tambalo, Simona Lodato · 2020 · Brain Research
  11. Human Pluripotent Stem Cell-Derived Neural Cells as a Relevant Platform for Drug Screening in Alzheimer’s Disease
    Juan Antonio García‐León, Laura Cáceres-Palomo, Elisabeth Sánchez‐Mejías, Marina Mejias‐Ortega, Cristina Nuñez‐Diaz, Juan José Fernandez-Valenzuela, Raquel Maria Sanchez-Varo, José Carlos Dávila, Javier Vitórica, Antonia Gutiérrez · 2020 · International Journal of Molecular Sciences
  12. Understanding and Treating Niemann–Pick Type C Disease: Models Matter
    Valentina Pallottini, Frank W. Pfrieger · 2020 · International Journal of Molecular Sciences
  13. Patient-Derived Induced Pluripotent Stem Cells (iPSCs) and Cerebral Organoids for Drug Screening and Development in Autism Spectrum Disorder: Opportunities and Challenges
    Chiara Villa, Romina Combi, Donatella Conconi, Marialuisa Lavitrano · 2021 · Pharmaceutics
  14. Novel in vitro Experimental Approaches to Study Myelination and Remyelination in the Central Nervous System
    Marangon, Davide, Caporale, Nicolò, Boccazzi, Marta, Abbracchio, Maria P., Testa, Giuseppe, Lecca, Davide · 2021 · Frontiers in Cellular Neuroscience
  15. Omics-based approaches to guide the design of biomaterials
    Anna L. Kersey, Thuy‐Uyen Nguyen, Biswadeep Nayak, Irtisha Singh, Akhilesh K. Gaharwar · 2023 · Materials Today
  16. Human brain development through the lens of cerebral organoid models
    Madeline G. Andrews, Tomasz Jan Nowakowski · 2019 · Brain Research
  17. Building the brain from scratch: Engineering region-specific brain organoids from human stem cells to study neural development and disease
    Fadi Jacob, Jordan G. Schnoll, Hongjun Song, Guo‐li Ming · 2021 · Current topics in developmental biology/Current Topics in Developmental Biology
  18. Advanced in vitro models: Microglia in action
    Cakir, Bilal, Kiral, Ferdi Ridvan, Park, In-Hyun · 2022 · Neuron
  19. PsychENCODE and beyond: transcriptomics and epigenomics of brain development and organoids
    Alexandre Jourdon, Soraya Scuderi, Davide Capauto, Alexej S. Abyzov, Flora Maria Vaccarino · 2020 · Neuropsychopharmacology
  20. Resolving Neurodevelopmental and Vision Disorders Using Organoid Single-Cell Multi-omics
    Giovanna Brancati, Barbara Treutlein, J. Gray Camp · 2020 · Neuron
  21. Growing Glia: Cultivating Human Stem Cell Models of Gliogenesis in Health and Disease
    Samantha N. Lanjewar, Steven A. Sloan · 2021 · Frontiers in Cell and Developmental Biology
  22. Studying the Brain in a Dish: 3D Cell Culture Models of Human Brain Development and Disease
    Juliana R. Brown, Giorgia Quadrato, Paola Arlotta · 2018 · Current topics in developmental biology/Current Topics in Developmental Biology
  23. Contribution of induced pluripotent stem cell technologies to the understanding of cellular phenotypes in schizophrenia
    Shabeesh Balan, Manabu Toyoshima, Takeo Yoshikawa · 2018 · Neurobiology of Disease
  24. Stem cell models of human synapse development and degeneration
    Emily S. Wilson, Karen Litwa · 2018 · Molecular Biology of the Cell
  25. Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function
    Ji‐Eun Kim, Jeffrey N. Savas, Meghan T. Miller, Xindao Hu, Cassiano Carromeu, Mathieu Lavallée‐Adam, Beatriz C.G. Freitas, Alysson Renato Muotri, John R. Yates, Anirvan Ghosh · 2019 · PLoS ONE
  26. An Overview of Astrocyte Responses in Genetically Induced Alzheimer’s Disease Mouse Models
    Fokion Spanos, Shane Antony Liddelow · 2020 · Cells
  27. Modeling traumatic brain injury with human brain organoids
    Dennis Jgamadze, Victoria E. Johnson, John A. Wolf, D. Kacy Cullen, Hongjun Song, Guo‐li Ming, Douglas H. Smith, Han-Chiao Isaac Chen · 2020 · Current Opinion in Biomedical Engineering
  28. Advances in Central Nervous System Organoids: A Focus on Organoid-Based Models for Motor Neuron Disease
    Renata Vieira de Sá, Marta Cañizares Luna, R. Jeroen Pasterkamp · 2021 · Tissue Engineering Part C Methods
  29. Brain Organoids: Filling the Need for a Human Model of Neurological Disorder
    Philip Jalink, Massimiliano Caiazzo · 2021 · Biology
  30. Assessing Gq-GPCR–induced human astrocyte reactivity using bioengineered neural organoids
    Caroline Cvetkovic, Rajan Patel, Arya J. Shetty, Matthew Hogan, Morgan Anderson, Nupur Basu, Samira Aghlara-Fotovat, Srivathsan Ramesh, Debosmita Sardar, Omid Veiseh A et al. · 2022 · The Journal of Cell Biology
  31. Lewy pathology formation in patient-derived GBA1 Parkinson’s disease midbrain organoids
    Emanuele Frattini, Gaia Faustini, Gianluca Lopez, Emma Veronica Carsana, Mattia Tosi, Ilaria Trezzi, Manuela Magni, Giulia Soldà, Letizia Straniero, Daniele Facchi et al. · 2024 · Brain
  32. Human neural organoid microphysiological systems show the building blocks necessary for basic learning and memory
    Dowlette‐Mary Alam El Din, Leah S. Mönkemöller, Alon Loeffler, Forough Habibollahi, Jack Schenkman, Amitav Mitra, Tjitse van der Molen, Lixuan Ding, Jason Laird, Maren Schenke et al. · 2025 · Communications Biology
  33. scBFA: modeling detection patterns to mitigate technical noise in large-scale single-cell genomics data
    Ruoxin Li, Gerald Quon · 2019 · Genome biology
  34. Modeling Cell-Cell Interactions in Parkinson’s Disease Using Human Stem Cell-Based Models
    Katrin Simmnacher, Jonas Lanfer, Tania Rizo, Johanna Kaindl, Beate Winner · 2020 · Frontiers in Cellular Neuroscience
  35. The Path to Progress Preclinical Studies of Age-Related Neurodegenerative Diseases: A Perspective on Rodent and hiPSC-Derived Models
    Gabriella MacDougall, Logan Y. Brown, Boris Kantor, Ornit Chiba‐Falek · 2021 · Molecular Therapy
  36. Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases
    Dorit Trudler, Swagata Ghatak, Stuart A. Lipton · 2021 · International Journal of Molecular Sciences
  37. Transcriptomic and morphological maturation of human astrocytes in cerebral organoids
    Marloes Verkerke, Amber Berdenis van Berlekom, Vanessa Donega, Daniëlle Vonk, Jacqueline A. Sluijs, Nayab F. Butt, Lois Kistemaker, Lot D. de Witte, R. Jeroen Pasterkamp, Jinte Middeldorp et al. · 2023 · Glia
  38. Sustained type I interferon signaling after human immunodeficiency virus type 1 infection of human iPSC derived microglia and cerebral organoids
    Andrew J. Boreland, Alessandro C. Stillitano, Hsin‐Ching Lin, Yara Abbo, Ronald P. Hart, Peng Jiang, Zhiping P. Pang, Arnold B. Rabson · 2024 · iScience
  39. Human Pluripotent Stem Cell-Derived Astrocyte Functionality Compares Favorably with Primary Rat Astrocytes
    Bas Lendemeijer, Maurits Unkel, Hilde Smeenk, Britt Mossink, Sara Hijazi, Sara Gordillo-Sampedro, Guy Shpak, Denise E. Slump, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken et al. · 2024 · eNeuro
  40. Advances in Modeling Alzheimer's Disease In Vitro
    Navatha Shree Sharma, Anik Karan, Dong-Hee Lee, Zheng Yan, Jingwei Xie · 2021 · Advanced NanoBiomed Research
  41. Cerebral Organoids as an Experimental Platform for Human Neurogenomics
    Tomasz Jan Nowakowski, Sofie R. Salama · 2022 · Cells
  42. Clinical relevance of animal models in aging-related dementia research
    Pranesh Padmanabhan, Jürgen Götz · 2023 · Nature Aging
  43. Modeling Pediatric Epilepsy through iPSC-Based Technologies
    Dina Simkin, Evangelos Kiskinis · 2018 · Epiliepsy currents/Epilepsy currents
  44. Examining the relationship between astrocyte dysfunction and neurodegeneration in ALS using hiPSCs
    Madeline Halpern, Kristen Brennand, James A. Gregory · 2019 · Neurobiology of Disease
  45. Comparison of Acute Effects of Neurotoxic Compounds on Network Activity in Human and Rodent Neural Cultures
    Lorena Saavedra, Kathleen Wallace, Theresa M. Freudenrich, Moritz Mall, William R. Mundy, Jorge Davila, Timothy J. Shafer, Marius Wernig, Daniel Haag · 2021 · Toxicological Sciences
  46. Efferocytosis Mediated Modulation of Injury after Neonatal Brain Hypoxia-Ischemia
    Jana Krystofova Mike, Donna Marie Ferriero · 2021 · Cells
  47. Mechanical regulation of oligodendrocyte biology
    Ekta Makhija, Daniela Espinosa-Hoyos, Anna Jagielska, Krystyn J. Van Vliet · 2019 · Neuroscience Letters
  48. Phospho-seq: integrated, multi-modal profiling of intracellular protein dynamics in single cells
    John D. Blair, Austin Hartman, Fides Lea Zenk, Philipp Wahle, Giovanna Brancati, Carol Dalgarno, Barbara Treutlein, Rahul Satija · 2025 · Nature Communications
  49. Electrophysiological and morphological characterization of single neurons in intact human brain organoids
    Corey R. Landry, Mighten C. Yip, Ying Zhou, Weibo Niu, Yunmiao Wang, Bo Yang, Zhexing Wen, Craig R. Forest · 2023 · Journal of Neuroscience Methods
  50. APOE deficiency impacts neural differentiation and cholesterol biosynthesis in human iPSC-derived cerebral organoids
    Zhao, Jing, Ikezu, Tadafumi C., Lu, Wenyan, Macyczko, Jesse R., Li, Yonghe, Lewis-Tuffin, Laura J., Martens, Yuka A., Ren, Yingxue, Zhu, Yiyang, Asmann, Yan W. et al. · 2023 · Stem Cell Research & Therapy
  51. Progression of mesenchymal stem cell regulation on imbalanced microenvironment after spinal cord injury
    Yifan Liu, Chenxi Zhao, Rong Zhang, Yilin Pang, Linquan Li, Shiqing Feng · 2024 · Stem Cell Research & Therapy
  52. Mapping the developmental trajectory of human astrocytes reveals divergence in glioblastoma
    Caitlin Sojka, Hsiao‐Lin V. Wang, Tarun N. Bhatia, Yangping Li, Pankaj Chopra, Anson Sing, Anna J. Voss, Alexia Tyler King, Feng Wang, Kevin Joseph et al. · 2025 · Nature Cell Biology
  53. Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes
    Mika Suga, Takayuki Kondo, Haruhisa Inoue · 2019 · International Journal of Molecular Sciences
  54. Taming human brain organoids one cell at a time
    Alexander Atamian, Lluís Cordón-Barris, Giorgia Quadrato · 2020 · Seminars in Cell and Developmental Biology
  55. Unraveling Human Brain Development and Evolution Using Organoid Models
    Sarah Fernandes, Davis Klein, Maria Carolina Marchetto · 2021 · Frontiers in Cell and Developmental Biology
  56. Interfacing brain organoids with precision medicine and machine learning
    Honghui Zheng, Yilin Feng, Jiyuan Tang, Shaohua Ma · 2022 · Cell Reports Physical Science
  57. A review on current brain organoid technologies from a biomedical engineering perspective
    Taylor Lokai, Bayne Albin, Khayzaran Qubbaj, Arjun Prasad Tiwari, Prashant Adhikari, In Hong Yang · 2023 · Experimental Neurology
  58. Retinal and Brain Organoids: Bridging the Gap Between in vivo Physiology and in vitro Micro-Physiology for the Study of Alzheimer’s Diseases
    Carlo Brighi, Federica Cordella, Luigi Chiriatti, Alessandro Soloperto, Silvia Di Angelantonio · 2020 · Frontiers in Neuroscience
  59. Cell-Biological Requirements for the Generation of Dentate Gyrus Granule Neurons
    Maryam Hatami, Sabine Conrad, Pooyan Naghsh, Gonzalo Álvarez-Bolado, Thomas Skutella · 2018 · Frontiers in Cellular Neuroscience
  60. Brain Organoids: Studying Human Brain Development and Diseases in a Dish
    Jie Xu, Zhexing Wen · 2021 · Stem Cells International
  61. Screening Platforms for Genetic Epilepsies—Zebrafish, iPSC-Derived Neurons, and Organoids
    Aleksandr Shcheglovitov, Randall Theodore Peterson · 2021 · Neurotherapeutics
  62. Modern approaches to investigating non‐neuronal aspects of Alzheimer's disease
    Shane Antony Liddelow · 2019 · The FASEB Journal
  63. Advances in human cellular mechanistic understanding and drug discovery of brain organoids for neurodegenerative diseases
    Lei Tong, Xiaoshuang Zhang, Gaoshuang Fu, Shaohan Luo, Ziwei Zhao, Shiwen Deng, Caifeng Li, Zhao Cui, Junxian Cao, Peng Chen et al. · 2024 · Ageing Research Reviews
  64. Human iPSC-derived microglial cells protect neurons from neurodegeneration in long-term cultured adhesion brain organoids
    Chen, Xianwei, Sun, Guoqiang, Feng, Lizhao, Tian, E, Shi, Yanhong · 2025 · Communications Biology
  65. A feedback-driven brain organoid platform enables automated maintenance and high-resolution neural activity monitoring
    Kateryna Voitiuk, Spencer T. Seiler, Mirella Pessoa de Melo, Jinghui Geng, Tjitse van der Molen, Sebastian Hernandez, Hunter E. Schweiger, Jessica L. Sevetson, David F. Parks, Ash Robbins et al. · 2025 · Internet of Things
  66. NFIB induces functional astrocytes from human pluripotent stem cell‐derived neural precursor cells mimicking in vivo astrogliogenesis
    Gyu‐Bum Yeon, Won‐Ho Shin, Seo Hyun Yoo, Dongyun Kim, Byeong‐Min Jeon, Won‐Ung Park, Yeonju Bae, Jae‐Yong Park, Seungkwon You, Dokyun Na et al. · 2021 · Journal of Cellular Physiology
  67. WWOX-Related Neurodevelopmental Disorders: Models and Future Perspectives
    Daniel J. Steinberg, Rami I. Aqeilan · 2021 · Cells
  68. When glia meet induced pluripotent stem cells (iPSCs)
    Li Li, Yanhong Shi · 2020 · Molecular and Cellular Neuroscience
  69. Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes
    Jiwen Li, Lin Pan, Marlesa I. Godoy, William G. Pembroke, Jessica E. Rexach, Michael C. Condro, Alvaro G. Alvarado, Mineli Harteni, Yen-Wei Chen, Linsey Stiles et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  70. An integrated transcriptomic cell atlas of human neural organoids
    Zhisong He, Leander Dony, Jonas Simon Fleck, Artur Szałata, Katelyn X. Li, Irena Slišković, Hsiu‐Chuan Lin, Małgorzata Santel, Alexander Atamian, Giorgia Quadrato et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  71. Organoid intelligence for developmental neurotoxicity testing
    Dowlette‐Mary Alam El Din, Jeongwon Shin, Alexandra Lysinger, Matthew J. Roos, Erik C. Johnson, Timothy J. Shafer, Thomas Härtung, Lena Smirnova · 2024 · Frontiers in Cellular Neuroscience
  72. One Step Into the Future: New iPSC Tools to Advance Research in Parkinson’s Disease and Neurological Disorders
    Nguyen‐Vi Mohamed, Frédérique Larroquette, Lenore K. Beitel, Edward A. Fon, Thomas M. Durcan · 2019 · Journal of Parkinson s Disease
  73. Cryptococcus neoformans–astrocyte interactions: effect on fungal blood brain barrier disruption, brain invasion, and meningitis progression
    Yeon Hwa Woo, Luis R. Martinez · 2021 · Critical Reviews in Microbiology
  74. Cerebral Organoids and Antisense Oligonucleotide Therapeutics: Challenges and Opportunities
    Jenny Lange, Haiyan Zhou, Amy McTague · 2022 · Frontiers in Molecular Neuroscience
  75. Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells
    Martin H. Berryer, Matthew Tegtmeyer, Loïc Binan, Vera Valakh, Anna J. Nathanson, Darina Trendafilova, Ethan Crouse, Jenny A. Klein, Daniel Meyer, Olli P. H. Pietiläinen et al. · 2023 · iScience
  76. Spatially Self‐Organized Three‐Dimensional Neural Concentroid as a Novel Reductionist Humanized Model to Study Neurovascular Development
    Yoke Chin Chai, San Kit To, Susan Simorgh, Samantha Zaunz, YingLi Zhu, Karan Ahuja, Alix Lemaitre, Roya Ramezankhani, Bernard K. van der Veer, Keimpe D. B. Wierda et al. · 2023 · Advanced Science
  77. iPSC-derived PSEN2 (N141I) astrocytes and microglia exhibit a primed inflammatory phenotype
    Michael A. Sullivan, Samuel D. Lane, André D. J. McKenzie, Sarah R. Ball, Margaret Sunde, G. Gregory Neely, Cesar L. Moreno, Alexandra Maximova, Eryn L. Werry, Michael Kassiou · 2024 · Journal of Neuroinflammation
  78. Advancing stroke recovery: unlocking the potential of cellular dynamics in stroke recovery
    Keivan Sahebi, Hassan Foroozand, Mobina Amirsoleymani, Saghi Eslamzadeh, Manica Negahdaripour, Amir Tajbakhsh, Abbas Rahimi Jaberi, Amir Savardashtaki · 2024 · Cell Death Discovery
  79. Methodologies for Generating Brain Organoids to Model Viral Pathogenesis in the CNS
    Hannah K. Hopkins, Elizabeth M. Traverse, Kelli L. Barr · 2021 · Pathogens
  80. Engineering Brain Organoids: Toward Mature Neural Circuitry with an Intact Cytoarchitecture
    Hyunsoo Jang, Seo Hyun Kim, Youmin Koh, Ki‐Jun Yoon · 2022 · International Journal of Stem Cells
  81. Implementation and validation of single-cell genomics experiments in neuroscience
    Marco Colonna, Geneviève Konopka, Shane Antony Liddelow, Tomasz Jan Nowakowski, Rajeshwar B. Awatramani, Helen S. Bateup, Cathryn René Cadwell, Emre Caglayan, Jerry L. Chen, Jesse Gillis et al. · 2024 · Nature Neuroscience
  82. Isolation of Human CD49f+ Astrocytes and In Vitro iPSC-Based Neurotoxicity Assays
    Lilianne Barbar, Tomasz Rusielewicz, Matthew Zimmer, Kriti Kalpana, Valentina Fossati · 2020 · STAR Protocols
  83. Microfabricated disk technology: Rapid scale up in midbrain organoid generation
    Nguyen‐Vi Mohamed, Paula Lépine, María Lacalle‐Aurioles, Julien Sirois, Meghna Mathur, Wolfgang Reintsch, Lenore K. Beitel, Edward A. Fon, Thomas M. Durcan · 2021 · Methods
  84. From Organoids to Assembloids: Experimental Approaches to Study Human Neuropsychiatric Disorders
    Rebecca J. Levy, Sergiu P. Pașca · 2025 · Annual Review of Neuroscience
  85. Electrophysiological Properties of Human Cortical Organoids: Current State of the Art and Future Directions
    Clara Zourray, Manju A. Kurian, Serena Barral, Gabriele Lignani · 2022 · Frontiers in Molecular Neuroscience
  86. What Makes Organoids Good Models of Human Neurogenesis?
    Qian Yang, Yan Hong, Ting Zhao, Hongjun Song, Guo‐li Ming · 2022 · Frontiers in Neuroscience
  87. Novel model of cortical–meningeal organoid co-culture system improves human cortical brain organoid cytoarchitecture
    E. Jalilian, S. Shin · 2023 · Scientific Reports
  88. Models for evaluating glioblastoma invasion along white matter tracts
    Yao Olive Li, Jun Wang, Si-rong Song, Shengqing Lv, Jianhua Qin, Shi‐Cang Yu · 2023 · Trends in biotechnology
  89. Guidelines for Manufacturing and Application of Organoids: Brain
    Taehwan Kwak, Si-Hyung Park, Siyoung Lee, Yujeong Shin, Ki‐Jun Yoon, Seung‐Woo Cho, Jong‐Chan Park, Seung-Ho Yang, Heeyeong Cho, Heh‐In Im et al. · 2024 · International Journal of Stem Cells
  90. Dysregulation of miRNA expression and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
    Dorit Trudler, Swagata Ghatak, Michael Bula, James Parker, Maria V. Talantova, Melissa Luevanos, Sergio R. Labra, Titas Grabauskas, Sarah Moore Noveral, Mayu Teranaka et al. · 2024 · Molecular Psychiatry
  91. In vitro and in silico Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and Treatment
    Megan Chesnut, Laura Sofia Munoz-Arcos, Georgina Harris, Dana M. Freeman, Lúcio Gama, Carlos A. Pardo, David Pamies · 2019 · Frontiers in Cellular and Infection Microbiology
  92. Human Induced Pluripotent Stem Cell Models of Neurodegenerative Disorders for Studying the Biomedical Implications of Autophagy
    Elena Seranova, Adina Maria Palhegyi, Surbhi Verma, Simona Dimova, Rachel Lasry, Moriyah Naama, Congxin Sun, Timothy Geoffrey Barrett, Tatiana Rosado Rosenstock, Dhiraj Kumar et al. · 2020 · Journal of Molecular Biology
  93. Human iPSC-Derived Glia as a Tool for Neuropsychiatric Research and Drug Development
    Johanna Heider, Sabrina Vogel, Hansjürgen Volkmer, Ricarda Breitmeyer · 2021 · International Journal of Molecular Sciences
  94. The potential application of organoids in breast cancer research and treatment
    Nasim Ebrahimi, Alireza Nasr Esfahani, Setare Samizade, Atena Mansouri, Masoud Ghanaatian, Samaneh Adelian, Vida Shadman-Manesh, Michael Richard Hamblin · 2021 · Human Genetics
  95. Synaptic Microcircuit Modeling with 3D Cocultures of Astrocytes and Neurons from Human Pluripotent Stem Cells
    Caroline Cvetkovic, Nupur Basu, Robert Krencik · 2018 · Journal of Visualized Experiments
  96. APOE4 impacts cortical neurodevelopment and alters network formation in human brain organoids
    Karina K. Meyer-Acosta, Eva Díaz‐Guerra, Parul Varma, Adyasha Aruk, Sara Mirsadeghi, Aranis Muniz Perez, Yousef Rafati, Ali Hosseini, Vanesa Nieto‐Estévez, Michèle Giugliano et al. · 2025 · Stem Cell Reports
  97. Host circuit engagement of human cortical organoids transplanted in rodents
    Kevin W. Kelley, Omer Revah, Felicity Gore, Konstantin Kaganovsky, Xiaoyu Chen, Karl A. Deisseroth, Sergiu P. Pașca · 2024 · Nature Protocols
  98. iPSC modeling of rare pediatric disorders
    Bethany A. Freel, Jordan N. Sheets, Kevin R. Francis · 2019 · Journal of Neuroscience Methods
  99. Human pluripotent stem cell-derived brain organoids as in vitro models for studying neural disorders and cancer
    Juan Luo, Peng Li · 2021 · Cell & Bioscience
  100. iPSC toolbox for understanding and repairing disrupted brain circuits in autism
    Simone Chiola, Nicolas Ulrich Edgar, Aleksandr Shcheglovitov · 2021 · Molecular Psychiatry