Synaptogyrin-3 Mediates Presynaptic Dysfunction Induced by Tau

McInnes, Joseph, Wierda, Keimpe, Snellinx, An, Bounti, Laura, Wang, Yu-Chun, Stancu, Ilie-Cosmin, Apóstolo, Nuno, Gevaert, Kris +6 more·2018·Neuron

Cited by (248)

Items 101–200 of 248

  1. Hippocampal neuronal loss and cognitive decline in LATE‐NC and ADNC among community‐dwelling older persons
    Sonal Agrawal, Lei Yu, Sue E. Leurgans, Sukriti Nag, Lisa Laverne Barnes, David A. A Bennett, Julie A. Schneider · 2025 · Alzheimer s & Dementia
  2. Autophagy in alzheimer disease pathogenesis and its therapeutic values
    Gabrielle Angst, Nuo Jia, Luis Tron Esqueda, Yanbo Fan, Qian Cai, Chenran Wang · 2025 · Autophagy Reports
  3. Alzheimer’s disease: an axonal injury disease?
    Dan Liang, Zhaohui Zhang · 2023 · Frontiers in Aging Neuroscience
  4. Early defects in translation elongation factor 1α levels at excitatory synapses in α-synucleinopathy
    Sonja Blumenstock, María Florencia Angelo, Finn Peters, Mario M. Dorostkar, Viktoria Ruf, Manja Luckner, Sophie Crux, Lenka Slapakova, Thomas Arzberger, Stéphane Claverol et al. · 2019 · Acta Neuropathologica
  5. The mitochondrial long non-coding RNA lncMtloop regulates mitochondrial transcription and suppresses Alzheimer’s disease
    Xiong, Wandi, Xu, Kaiyu, Sun, Jacquelyne Ka-Li, Liu, Siling, Zhao, Baizhen, Shi, Jie, Herrup, Karl, Chow, Hei-Man, Lu, Lin, Li, Jiali · 2024 · The EMBO Journal
  6. Acacia catechu Willd. Extract Protects Neuronal Cells from Oxidative Stress-Induced Damage
    Elda Chiaino, Roberto Stella, Caterina Peggion, Matteo Micucci, Roberta Budriesi, Laura Mattioli, Carla Marzetti, Federica Pessina, Massimo Valoti, Maria Frosini · 2021 · Antioxidants
  7. Transcriptional Regulation of the Synaptic Vesicle Protein Synaptogyrin-3 (SYNGR3) Gene: The Effects of NURR1 on Its Expression
    Lingfei Li, Philip Wing‐Lok Ho, Huifang Liu, Shirley Yin-Yu Pang, Eunice Eun-Seo Chang, Zoe Yuen-Kiu Choi, Yasine Malki, Michelle Hiu-Wai Kung, David Boyer Ramsden, Shu‐Leong Ho · 2022 · International Journal of Molecular Sciences
  8. Longitudinal synaptic loss versus tau Braak staging in amnestic mild cognitive impairment
    Greet Vanderlinden, Michel J. B. Koole, Laura Michiels, Robin Lemmens, Mathieu Vandenbulcke, Koen Van Laere · 2024 · Alzheimer s & Dementia
  9. Tau suppresses neuronal activity in vivo, even before tangles form
    Marc Aurel Busche · 2019 · Brain
  10. Cleavage of human tau at Asp421 inhibits hyperphosphorylated tau induced pathology in a Drosophila model
    Hao Chi, Sun Lee, Ren-Huei Shiu, Rui Han, Chien-Ping Hsieh, Tzu-Min Wei, Chung‐Chuan Lo, Hui-Yun Chang, Tzu‐Kang Sang · 2020 · Scientific Reports
  11. The PANoptosis-related hippocampal molecular subtypes and key biomarkers in Alzheimer’s disease patients
    Chen‐Long Li, Qi Wang, Li Wu, Jing-Yi Hu, Qi-Chao Gao, Xin-long Jiao, Yuxiang Zhang, Shan Tang, Yu Ming Qi, P. F. He · 2024 · Scientific Reports
  12. Single‐microglia transcriptomic transition network‐based prediction and real‐world patient data validation identifies ketorolac as a repurposable drug for Alzheimer's disease
    Jielin Xu, Wenqiang Song, Zhenxing Xu, Michael M. Danziger, Ehud Karavani, Chengxi Zang, Xin Chen, Yichen Li, Isabela Rivera Paz, Dhruv Gohel et al. · 2024 · Alzheimer s & Dementia
  13. CNS cell type–specific gene profiling of P301S tau transgenic mice identifies genes dysregulated by progressive tau accumulation
    Yazi Diana Ke, Gabriella Chan, Kristie Stefanoska, Carol G. Au, Mian Bi, Julius Müller, Magdalena Przybyla, Astrid Feiten, Emmanuel Prikas, Glenda Margaret Halliday et al. · 2019 · Journal of Biological Chemistry
  14. Presynaptic Pathophysiology Encoded in Different Domains of Tau – Hyper-Versus Hypoexcitability?
    Jochen Martin Decker, Eva‐Maria Mandelkow · 2019 · Advances in experimental medicine and biology
  15. In vivo overexpression of synaptogyrin‐3 promotes striatal synaptic dopamine uptake in LRRK2 R1441G mutant mouse model of Parkinson's disease
    Philip Wing‐Lok Ho, Lingfei Li, Hui‐Fang Liu, Zoe Yuen-Kiu Choi, Eunice Eun Seo Chang, Shirley Yin‐Yu Pang, Yasine Malki, Chi-Ting Leung, Michelle Hiu-Wai Kung, David Boyer Ramsden et al. · 2023 · Brain and Behavior
  16. Therapies for Tau-associated neurodegenerative disorders: targeting molecules, synapses, and cells
    Miranda Robbins · 2023 · Neural Regeneration Research
  17. The Prion Protein Regulates Synaptic Transmission by Controlling the Expression of Proteins Key to Synaptic Vesicle Recycling and Exocytosis
    Caterina Peggion, Roberto Stella, Francesco Chemello, Maria Lina Massimino, Giorgio Arrigoni, Stefano Cagnin, Giancarlo Biancotto, Cinzia Franchin, Maria Catia Sorgato, Alessandro Bertoli · 2018 · Molecular Neurobiology
  18. Tau Isoform Profile in Essential Tremor Diverges From Other Tauopathies
    Soong Ho Kim, Kurt W. Farrell, Stephanie Cosentino, Jean‐Paul Vonsattel, Phyllis L. Faust, Etty Paola Cortes, David A Bennet, Elan D. Louis, John F. Crary · 2021 · Journal of Neuropathology & Experimental Neurology
  19. A Connected Network of Interacting Proteins Is Involved in Human-Tau Toxicity in Drosophila
    Sébastien Feuillette, Camille Charbonnier, Thierry Frébourg, Dominique Campion, Magalie Lecourtois · 2020 · Frontiers in Neuroscience
  20. ApoE-calypse tau: ApoE–tau synergy in Alzheimer’s disease
    Matthew Paul Lennol, Chiara Bordier, Léana Kamelher, Jason D. Ulrich, David M. Holtzman, Maud Gratuze · 2025 · The Journal of Experimental Medicine
  21. The interaction of Synapsin 2a and Synaptogyrin-3 regulates fear extinction in mice
    Xi-Ya Shen, Juan Zhang, He-Zhou Huang, Shaohong Li, Ling Zhou, Shiping Wu, Cheng Tang, Xian Huang, Zhiqin Liu, Zi-Yuan Guo et al. · 2024 · Journal of Clinical Investigation
  22. Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent Networks
    Karima Schwab, Valeria Melis, Charles R. Harrington, Claude M. Wischik, Mandy Magbagbeolu, Franz Theuring, Gernot Riedel · 2021 · Cells
  23. Identification of phosphorylated tau protein interactors in progressive supranuclear palsy ( PSP ) reveals networks involved in protein degradation, stress response, cytoskeletal dynamics, metabolic processes, and neurotransmission
    Rowan A. W. Radford, Stephanie L. Rayner, Paulina Szwaja, Marco Morsch, Flora Cheng, Tianyi Zhu, Jocelyn Widagdo, Victor Anggono, Dean L. Pountney, Roger S. Chung et al. · 2023 · Journal of Neurochemistry
  24. Unknown roles of tau pathology in neurological disorders. Challenges and new perspectives
    Margrethe A. Olesen, Francisca Villavicencio-Tejo, Victor Cuevas-Espinoza, Rodrigo A. Quintanilla · 2024 · Ageing Research Reviews
  25. rTg(TauP301L)4510 mice exhibit increased VGlut1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release
    Erika Taipala, Jeremiah C. Pfitzer, Morgan Hellums, Miranda Nicole Reed, Michael W. Gramlich · 2022 · Frontiers in Synaptic Neuroscience
  26. Advancing medicine for Alzheimer’s disease: A plasma neural exosome platform
    Edward J. Goetzl · 2020 · The FASEB Journal
  27. TauP301L disengages from the proteosome core complex and neurogranin coincident with enhanced neuronal network excitability
    Katriona L. Hole, Bangfu Zhu, Laura Huggon, Jon T. Brown, Jody M. Mason, Robert J. Williams · 2024 · Cell Death and Disease
  28. Alzheimer’s Disease: Is a Dysfunctional Mevalonate Biosynthetic Pathway the Master-Inducer of Deleterious Changes in Cell Physiology?
    Arnold DE LOOF, Liliane Schoofs · 2019 · OBM Neurobiology
  29. The microtubule-associated protein Tau suppresses the axonal distribution of PDF neuropeptide and mitochondria in circadian clock neurons
    Melanie Y Zhang, Bridget C. Lear, Ravi Allada · 2021 · Human Molecular Genetics
  30. The Fate of Tau Aggregates Between Clearance and Transmission
    Assel Seitkazina, Kyu Hyeon Kim, Erin Fagan, Yoonsik Sung, Yun Kyung Kim, Sungsu Lim · 2022 · Frontiers in Aging Neuroscience
  31. Biomarkers of Activity-Dependent Plasticity and Persistent Enhancement of Synaptic Transmission in Alzheimer Disease: A Review of the Current Status
    Marcin Warpechowski, Jędrzej Jan Warpechowski, Agnieszka Kulczyńska‐Przybik, Barbara Mroczko · 2022 · Medical Science Monitor
  32. Unveiling the significance of synaptic proteins in parkinson's pathogenesis: A review
    Ritu Soni, Jigna Shah · 2025 · International Journal of Biological Macromolecules
  33. Targeting pre-synaptic tau accumulation: a new strategy to counteract tau-mediated synaptic loss and memory deficits
    Maud Gratuze, David M. Holtzman · 2021 · Neuron
  34. Metabotropic Glutamate Receptors Modulate Exocytotic Tau Release and Propagation
    Francesca Mazzo, Ioana Butnaru, Olivera Grubisha, Elena Ficulle, Helen Sanger, Griffin J. Fitzgerald, Feng Pan, Francesca Pasqui, Tracey K. Murray, James A. Monn et al. · 2022 · Journal of Pharmacology and Experimental Therapeutics
  35. Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy
    Changyi Ji, Xiaofeng Yang, Mohamed Eleish, Yixiang Jiang, Amber M. Tetlow, Soomin C. Song, Alejandro Martín‐Ávila, Qian Wu, Yanmei Zhou, Wen‐Biao Gan et al. · 2024 · Alzheimer s & Dementia
  36. Botulinum neurotoxin A modulates the axonal release of pathological tau in hippocampal neurons
    Chiara Panzi, Sunaina Surana, Samantha De La‐Rocque, Edoardo Moretto, Oscar M. Lazo, Giampietro Schiavo · 2023 · Toxicon
  37. Tau‐mediated synaptic dysfunction is coupled with HCN channelopathy
    Despoina Goniotaki, Francesco Tamagnini, Luca Biasetti, Svenja-Lotta Rumpf, Claire Troakes, Saskia J. Pollack, Shalom Ukwesa, Haoyue Sun, Igor Kraev, Louise C. Serpell et al. · 2024 · Alzheimer s & Dementia
  38. SYNGR4 and PLEKHB1 deregulation in motor neurons of amyotrophic lateral sclerosis models: potential contributions to pathobiology
    Rita F Marques, Kent E. Duncan · 2021 · Neural Regeneration Research
  39. Diverse influences on tau aggregation and implications for disease progression
    Meaghan Van Alstyne, James Pratt, Roy Parker · 2025 · Genes & Development
  40. The Drosophila melanogaster as Genetic Model System to Dissect the Mechanisms of Disease that Lead to Neurodegeneration in Adrenoleukodystrophy
    Bülow, Margret H., Parsons, Brendon D., Di Cara, Francesca · 2020 · Advances in Experimental Medicine and Biology
  41. Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
    Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser, María Luisa Franco, Burcu Özcan, Diana Gomes Moreira, Dmitry Karachentsev et al. · 2023 · eLife
  42. Tau isoform-specific enhancement of L-type calcium current and augmentation of afterhyperpolarization in rat hippocampal neurons
    Georgiana F. Stan, Timothy W. Church, Ellie Randall, Jenna R. M. Harvey, Jon T. Brown, Kevin A. Wilkinson, Jonathan G. Hanley, Neil V. Marrion · 2022 · Scientific Reports
  43. Fibre density and cross-section associate with hallmark pathology in early Alzheimer’s disease
    G. Vanderlinden, A. Radwan, Danny Christiaens, J. Blommaert, Stefan Sunaert, M. Vandenbulcke, M. Koole, K. van Laere · 2025 · Alzheimer's Research & Therapy
  44. Tau phosphorylation homeostasis: Mechanisms, targets, and therapeutic implications in Alzheimer’s disease
    ShengWen Lu, Shi Qiu, Guan Yu, Aihua Zhang, Qiqi Zhao · 2026 · Ageing Research Reviews
  45. Torpor induces reversible tau hyperphosphorylation and accumulation in mice expressing human tau
    Christina F. de Veij Mestdagh, M. E. Witte, Wiep Scheper, A.B. Smit, Robert H. Henning, Ronald E. van Kesteren · 2024 · Acta Neuropathologica Communications
  46. Maintained memory and long‐term potentiation in a mouse model of Alzheimer's disease with both amyloid pathology and human tau
    Jane Tulloch, Olga Netsyk, Eleanor K. Pickett, Abigail G. Herrmann, Pooja Jain, Anna J. Stevenson, Iris Oren, Oliver M. Hardt, Tara L. Spires‐Jones · 2020 · European Journal of Neuroscience
  47. FTD-associated mutations in Tau result in a combination of dominant and recessive phenotypes
    Alexander D. Law, Marlène Cassar, Dani M. Long, Eileen S. Chow, Jadwiga Maria Giebultowicz, Anjana Venkataramanan, Roland Strauß, Doris Kretzschmar · 2022 · Neurobiology of Disease
  48. Transcriptomic profiling of the developing brain revealed cell-type and brain-region specificity in a mouse model of prenatal stress
    Yuhao Dong, Jie Weng, Yueyan Zhu, Daijing Sun, Wei He, Qi Chen, Jin Cheng, Ying Zhu, Yan Jiang · 2023 · BMC Genomics
  49. Reversal of Tau-Dependent Cognitive Decay by Blocking Adenosine A1 Receptors: Comparison of Transgenic Mouse Models with Different Levels of Tauopathy
    Marta Anglada‐Huguet, Heike Endepols, Astrid Sydow, Ronja Hilgers, Bernd Neumaier, Alexander E. Drzezga, Senthilvelrajan Kaniyappan, Eckhard Mandelkow�, Eva-Maria Mandelkow · 2023 · International Journal of Molecular Sciences
  50. Hyperactive neuronal networks enhance tau spread in an Alzheimer’s disease mouse model
    Aaron J Barbour, Keegan Hoag, Eli J. Cornblath, Abigail Chavez, Alfredo Lucas, Xiaofan Li, Sydney E Zebrowitz, Chloe Hassman, Omar Vazquez, Sharon X. Xie et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  51. Melanin and Neurotransmitter Signalling Genes Are Differentially Co‐Expressed in Growing Feathers of White and Rufous Barn Owls
    Anne‐Lyse Ducrest, Luis M. San‐Jose, Samuel Neuenschwander, Emanuel Schmid‐Siegert, Céline Simon, Marco Pagni, Christian Iseli, Hannes Richter, Nicolas Guex, Tristan Cumer et al. · 2025 · Pigment Cell & Melanoma Research
  52. Hydromethylthionine rescues synaptic SNARE proteins in a mouse model of tauopathies: Interference by cholinesterase inhibitors
    Karima Schwab, Dilyara Lauer, Mandy Magbagbeolu, Franz Theuring, Anna Gąsiorowska, Maciej Zadrożny, Charles R. Harrington, Claude M. Wischik, Grażyna Niewiadomska, Gernot Riedel · 2024 · Brain Research Bulletin
  53. Intraluminal Farnesol and Farnesal in the Mealworm's Alimentary Canal: An Unusual Storage Site Uncovering Hidden Eukaryote Ca2+-Homeostasis-Dependent “Golgicrine” Activities
    Arnold DE LOOF, Liliane Schoofs · 2019 · Frontiers in Endocrinology
  54. Intra-cellular accumulation of amyloid is a marker of selective neuronal vulnerability in Alzheimer’s disease
    Alessia Caramello, Nurun Nahar Fancy, Clotilde Tournerie, Maxine Eklund, Vicky M. N. Chau, Emily Adair, Marianna Papageorgopoulou, Johanna Jackson, John Hardy, Paul McMahan Matthews · 2023 · medRxiv
  55. Association of reduced cerebrospinal fluid NPTX2 levels with postoperative delirium in patients undergoing knee/hip replacement: a prospective cohort study
    Zongxiao Guo, Xiaoli Hong, Xiang Wang, Weiguo Chen, Zongfeng Guo · 2024 · Aging Clinical and Experimental Research
  56. Rivastigmine interferes with the pharmacological activity of hydromethylthionine on presynaptic proteins in the line 66 model of frontotemporal dementia
    Karima Schwab, Lianne Robinson, Anne Annschuetz, Eline Dreesen, Mandy Magbagbeolu, Valeria Melis, Franz Theuring, Charles R. Harrington, Claude M. Wischik, Gernot Riedel · 2024 · Brain Research Bulletin
  57. Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle
    Nastaran Samimi, Akiko Asada, Kanae Ando · 2020 · Galen Medical Journal
  58. Evidence for trans-synaptic propagation of oligomeric tau in Progressive Supranuclear Palsy
    Robert I. McGeachan, Lois Keavey, Jamie L. Rose, Elizabeth M. Simzer, Ya Yin Chang, Maxwell P Spires-Jones, Mollie Gilmore, Natalia Ravingerova, Cristina Scutariu, Lewis W. Taylor et al. · 2022 · medRxiv
  59. Synaptogyrin regulates neuronal activity-induced autophagy to degrade synaptic vesicle components and pathological Tau
    Sergio Hernández-Díaz, Pilar Martinez-Olondo, Irene Sanchez-Mirasierra, Carla Montecinos-Oliva, Saurav Ghimire, James D. Sutherland, Rosa Barrio, Sandra‐Fausia Soukup · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  60. Tau oligomers modulate synapse fate by eliciting progressive bipartite synapse dysregulation and synapse loss
    Kristeen A. Pareja-Navarro, Christina D. King, Grant Kauwe, Yani Y. Ngwala, Doyle Lokitiyakul, Ivy Wong, Aaryan Vira, Yaofu Liu, Jackson H. Chen, Mahima Sharma et al. · 2026 · Molecular Neurodegeneration
  61. Axonal tau reduction ameliorates tau and amyloid pathology in a mouse model of Alzheimer’s disease
    Abdolhossein Zare, Saeede Salehi, Jakob Maximilian Bader, Anna-Lena Wiessler, Manuela Prokesch, Vincent Albrecht, Carmen Villmann, Matthias Mann, Michael Briese, Michael Sendtner · 2025 · Translational Neurodegeneration
  62. Tau and Alzheimer’s Disease: Molecular Mechanisms and Treatment Approaches
    Allison Bethanne Reiss, Dalia Muhieddine, Ariel Z. De Leon, Iryna Voloshyna, Irving H. Gomolin, Aaron Pinkhasov · 2021 · SN Comprehensive Clinical Medicine
  63. Enhancing Lateral Resolution Using Two‐Colour Direct Stochastic Optical Reconstruction Microscopy to Unravel Synaptic Tau Pathology in Alzheimer's Disease
    Érika Sánchez‐Aced, Borja Moya‐Llamas, Joaquim Aumatell Escabias, Soraya Torres, Martí Colom‐Cadena, Jordi Pegueroles, Cristian José de Quintana-Schmidt, Àlex Bayés, Laura Molina‐Porcel, Ibán Aldecoa et al. · 2025 · Neuropathology and Applied Neurobiology
  64. Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling
    Katarzyna Marta Zoltowska, Utpal Das, Sam Lismont, Thomas Enzlein, Masato Maesako, Mei CQ Houser, María Luisa Franco, Burcu Özcan, Diana Gomes Moreira, Dmitry Karachentsev et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  65. Leveraging Proteomics to Explore the Molecular Mechanisms of Primary Tauopathies
    Laura R. Nementzik, Tomas Kavanagh, Sian Genoud, Eleanor Drummond · 2025 · Journal of Neurochemistry
  66. Graded regulation of microtubule-binding of Tau by the phosphorylation state of the proline-rich region in living neurons
    Nakata, Rinaho, Torii, Tomohiro, Miyasaka, Tomohiro, Misonou, Hiroaki · 2026 · Neuroscience Research
  67. Recent molecular insights and biosensor-based diagnostic technologies for hyperphosphorylated Tau in Alzheimer's disease
    Samah Shabana, Hamed I. Hamouda, Angyang Shang, Shuai Shao, Jinyuan Zhao, Hong Yuan, Bo Liu · 2025 · Alzheimer s Research & Therapy
  68. Early synaptic pathology is associated with small tau aggregates in Alzheimer’s disease
    Emre Fertan, Shekhar Kedia, George Nolan, Georg Meisl, Matthew W. Cotton, Karin H. Müller, Ziwei Zhang, Leila Mureşan, Annelies Quaegebeur, Maria Grazia Spillantini et al. · 2026 · Acta Neuropathologica
  69. Disruption of Synaptic Vesicle Trafficking in Alzheimer’s and Parkinson’s Disease: Mechanisms and Therapeutic Implication
    Youyang Zhu, Lianna Zhao, Yingming Li, Miao Tian, Yingdi Liao, Jhen-Li Huang, Peixin Guo, Yuhuan Xie · 2026 · International Journal of Molecular Sciences
  70. Dysregulation of autophagosome–mitochondria contacts contributes to autophagy dysfunction and neurodegeneration in tauopathy
    Nuo Jia, Hongyuan Guan, Yantao Zuo, Yu Young Jeong, Niharika Amireddy, Gavesh Rajapaksha, Cuauhtemoc Ulises Gonzalez, Nora Jaber, Y Lee, Marialaina Nissenbaum et al. · 2026 · Proceedings of the National Academy of Sciences
  71. Regulation of presynaptic homeostatic plasticity by glial signalling in Alzheimer's disease
    Yimei Cai, Tingting Wang · 2024 · The Journal of Physiology
  72. A comprehensive review on novel opportunities for Alzheimer therapy by targeting BIN1
    Trina Saha, Dipanjan Karati · 2025 · Egyptian Journal of Medical Human Genetics
  73. Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer
    Ryan M. Murphy, Jason Tasoulas, Alessandro Porrello, Miranda B. Carper, Yi‐Hsuan Tsai, Alisha R. Coffey, Sunil Kumar, Peter YF. Zeng, Travis Parke Schrank, Bentley R. Midkiff et al. · 2022 · Cancer Research Communications
  74. Insights to develop tau‐directed therapeutics to protect the synaptic integrity for tauopathies
    Eunji Cha, Hak Joong Kim, Sang Min Lim · 2023 · Bulletin of the Korean Chemical Society
  75. Development of MAPT S305 mutation models exhibiting elevated 4R tau expression, resulting in altered neuronal and astrocytic function
    Kathryn R. Bowles, DA Pugh, Chiara Pedicone, Laura‐Maria Oja, S A Weitzman, Yale Liu, Ji‐Long Chen, Matthew David Disney, Alison Goate · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  76. Tau Axonal Sorting and Interaction With Synaptic Plasticity Modulators Is Domain‐ and Isoform‐Dependent in Human iPSC ‐Derived Neurons
    Michael Bell‐Simons, Helen Breuer, Laura Wunderlich, Hanin Chmes, Daniel Adam, Jennifer Klimek, Sarah Buchholz, Hans Zempel · 2025 · Aging Cell
  77. Brain-derived synaptic vesicles have an intrinsic ability to sequester tubulin
    Tiago Mimoso, Александр Коробейников, Alexander Stein, Dragomir Milovanović, Silvio O. Rizzoli, Sarah Köster, Sofiia Reshetniak · 2025 · BMC Biology
  78. Synaptogyrin-3 plays a critical role in addiction-related dopamine dysfunction and behavioral maladaptations
    Emily G. Peck, Soren D. Emerson, Alyson M. Curry, Kimberly M. Holter, Paige M. Estave, Jonathon P. Sens, Olivia A. Colarusso, Sean P. Farris, Drew D. Kiraly, Robert W. Gould et al. · 2026 · Proceedings of the National Academy of Sciences
  79. Super-Resolution Imaging of Tau Proteins in Isolated and Immobilized Brain Synaptosomes
    Qixu Cai, Hwan‐Ching Tai · 2024 · Methods in molecular biology
  80. Conformation pattern changes in R1-pS262 tau peptide induced endogenous tau aggregation, synaptic damage, and cognitive impairments
    Gang Wu, Yong Luo, Qian Guo, Mingming Yang, Yacoubou Abdoul Razak Mahaman, Yi Liu, Jian‐Zhi Wang, Rong Liu, Xiang Gao, Xiaochuan Wang · 2024 · Journal of Alzheimer s Disease
  81. APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model
    Sarah Vanherle, Art Janssen, Manuel Gutiérrez de Ravé, Bieke Janssen, Chritica Lodder, Pablo Botella Lucena, Sofie Kessels, Jana Hardy, Eline Vandeput, Yanyan Wang et al. · 2025 · Molecular Psychiatry
  82. Investigating the effects of chronic perinatal alcohol and combined nicotine and alcohol exposure on dopaminergic and non-dopaminergic neurons in the VTA
    Tina Kazemi, Shuyan Huang, Naze G. Avci, Yasemin M. Akay, Metin Akay · 2021 · Scientific Reports
  83. Purification of Soluble Recombinant Human Tau Protein from Bacteria Using Double-tag Affinity Purification
    Joseph McInnes, Lujia Zhou, Patrik Verstreken · 2018 · BIO-PROTOCOL
  84. Patent Highlights December 2018–January 2019
    Hermann AM Mucke · 2019 · Pharmaceutical Patent Analyst
  85. Reducing Tau Ameliorates Behavioural and Transcriptional Deficits in a Novel Model of Alzheimer's Disease
    Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly M. Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Louise Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad et al. · 2018 · SSRN Electronic Journal
  86. APOE4 Regulates Synaptic Function by Directly Modulating the SNARE Complex Assembly
    Feng Chen, Yanting Chen, Huiyi Chen, Yongxiang Wang, Wenyan Wei, Yujie Cai, Chunmei Liang, Hao Cao, Xiongjin Chen, Yao Ji et al. · 2021 · Research Square
  87. Whole-brain modeling of the differential influences of Amyloid-Beta and Tau in Alzheimer’s Disease
    Gustavo Patow, Leon Stefanovski, Petra Ritter, Gustavo Deco, Xenia Kobeleva, the Alzheimer’s Disease Neuroimaging Initiative · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  88. Mitochondrial bioenergetics stimulates autophagy for pathological tau clearance in tauopathy neurons
    Nuo Jia, Dhasarathan Ganesan, Hongyuan Guan, Yu Young Jeong, Sinsuk Han, Marialaina Nissenbaum, Alexander W. Kusnecov, Qian Cai · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  89. Axonal Tau sorting depends on the PRR2 domain and 0N4R-specific interactions hint at distinct roles of Tau isoforms in synaptic plasticity
    M. Bell-Simons, Sarah Buchholz, J. Klimek, Hans Zempel · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  90. Tau Pathology in Alzheimer's Disease: Bridging Molecular Mechanisms and Targeted Therapies
    Mini Dahiya, Monu Yadav, Anil Kumar, Chetan Goyal · 2025 · CNS & Neurological Disorders - Drug Targets
  91. SYNGR3 Accelerates α‐Synuclein Aggregation and Neurodegeneration in Parkinson's Disease
    Xin Wang, Jiaolong Yang, Ziku Wang, Zhichao Liu, Wei Tan, Zhentao Zhang · 2026 · CNS Neuroscience & Therapeutics
  92. Integrative Structural Bioinformatics and Molecular Dynamics Analyses of Synaptic Vesicle Proteins and Their Water-Soluble QTY-Variants Reveal Membrane Constraints and Evolutionary Coupling of T ⇔ V
    Taner Karagöl, Alper Karagöl, Shuguang Zhang · 2026 · Journal of Molecular Evolution
  93. Novel Therapeutic Targets for Treating Alzheimer’s Disease
    Magham Sai Varshini, Ammu V. V. V. Ravi Kiran, Kusuma Kumari Garikapati, Praveen Thaggikuppe Krishnamurthy, Vaishali Manikrao Patil, Renat R. Khaydarov · 2023 · Springer eBooks
  94. Wherefore Art Tau? Functional importance of site-specific tau phosphorylation in diverse subcellular domains
    Amanda K. Schneeweis, Daniel T.S. Pak · 2023 · The International Journal of Biochemistry & Cell Biology
  95. Tau Abnormalities and Autophagic Defects in Neurodegenerative Disorders; A Feed-forward Cycle
    Nastaran Samimi, Akiko Asada, Kanae Ando · 2020 · Galen Medical Journal
  96. The mtDNA-derived lncMtDloop promotes mitochondrial homeostasis maintenance and implications in AD
    Wandi Xiong, Kaiyu Xu, Jacquelyne Ka‐Li Sun, Siling Liu, Baizhen Zhao, Jie Shi, Karl Herrup, Hei‐Man Chow, Lin Lü, Jiali Li · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  97. Tau-seed interactome analysis reveals distinct functional signatures in Alzheimer’s disease across model systems
    Pablo Martínez, Henika Patel, Yanwen You, Daniella Lopes, Armando Amaro, Nur Jury, Yuhao Min, Javier Redding‐Ochoa, Sayan Dutta, Jean‐Christophe Rochet et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  98. APP accumulates around dense-core amyloid plaques with presynaptic proteins in Alzheimer’s disease brain
    Tomás Jordá-Siquier, Melina Petrel, Vladimir Kouskoff, Fabrice P. Cordelières, Susanne Frykman, Ulrike C. Müller, Christophe Mulle, Gaël Barthet · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  99. Need for more holistic therapeutic and management strategies to understand the causal or correlative link of the Aβ amyloid pathway with Alzheimer’s disease for a more efficiënt treatment
    Jean‐Pierre Timmermans · 2018 · Peptides
  100. FENS ‐Kavli winter symposium: Addressing the cellular phase of dementia—visions of the UK Dementia Research Institute
    Raphael Hesse, Christopher M. Henstridge · 2018 · European Journal of Neuroscience