A combination of ontogeny and CNS environment establishes microglial identity
Bennett, F. Chris, Bennett, Mariko L., Yaqoob, Fazeela, Mulinyawe, Sara B., Grant, Gerald A., Hayden Gephart, Melanie, Plowey, Edward D., Barres, Ben A.·2018·Neuron
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- Bacterial infection reshapes monocyte and macrophage ontogeny at the CNS bordersVitka Gres, Florens Lohrmann, Vidmante Fuchs, Jana Neuber, Zohreh Mansoori Moghadam, Anne Kathrin Lößlein, Lance Fredrick Pahutan Bosch, Tiago Figueiral-Martins, Sebastian Baasch, David Obwegs et al. · 2026 · Science Immunology
- Depletion and replacement of tissue-resident macrophages in mice with germ-line deletion of a conserved enhancer in the Csf1r locusYajun Liu, Sébastien Jacquelin, Isis Taylor, Emma K. Green, Omkar L. Patkar, Sahar Keshvari, Ginell N. Ranpura, Conan J O O’Brien, Eline E. Jessen, Emma L. Maxwell et al. · 2026 · Development
- APOE3 and APOE4 human astrocytes differentially modulate Alzheimer’s disease pathology and microglial responses in chimeric miceJoan Cruz-Sesé, Marta Miron-Alcala, María Alfonso-Triguero, Jon Olalde, Leire Ruiz, Nuria Galbis-Gramage, Lorea Cortés, Laura Escobar, Pranav Preman, An Snellinx et al. · 2026 · Cell Reports
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- The Effect of Systemic Inflammation on Cognitive Function and Neurodegenerative DiseaseColm M. Cunningham, Donal Skelly · 2021 · Cambridge University Press eBooks
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- New Insights into Microglia as Therapeutic Targets in Alzheimer’s DiseaseDeepa S. Mandlik, Satish K. Mandlik, Heena Bholaram Choudhary · 2023 · Current Drug Therapy
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- Essential contributions of enhancer genomic regulatory elements to microglial cell identity and functionsAndré Machado Xavier, Sarah Belhocine, David Gosselin · 2019 · WIREs Systems Biology and Medicine
- Microglia and border-associated macrophages in the central nervous systemNágela Ghabdan Zanluqui, Carolina Manganeli Polonio, Marília Garcia de Oliveira, Lilian Gomes de Oliveira, L.C. Faria, Jean Pierre Schatzmann Peron · 2022 · Elsevier eBooks
- Recent topics regarding macrophage in the central nervous systemTakahiro Masuda · 2022 · The Journal of Biochemistry
- Microglia: A Critical Cell for NeurodevelopmentChristopher A. McPherson, Gaylia Jean Harry · 2022 · Springer eBooks
- Single-cell transcriptomic profile reveals macrophage heterogeneity in medulloblastoma and their treatment-dependent recruitmentMai T. Dang, Michael Gonzalez, Krutika Satish Gaonkar, Komal S. Rathi, Patricia Ann Young, Sherjeel Arif, Li Zhai, Md. Zahidul Alam, Samir Devalaraja, Tsun Ki Jerrick To et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Sex hormones underlying 17a-Estradiol effects on neuroinflammationLucas Kniess Debarba, Hashan S. M. Jayarathne, Richard A. Miller, Michael Garratt, Marianna Sadagurski · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Spatiotemporal Dynamics of Human Microglia are Linked with Brain Developmental Processes Across the LifespanDavid A. Menassa, Tim A.O. Muntslag, María Martín‐Estebané, Liam Barry-Carroll, Mark A. Chapman, István Adorján, Teadora Tyler, Bethany Turnbull, Matthew J.J. Rose-Zerilli, James A. R. Nicoll et al. · 2021 · SSRN Electronic Journal
- Brain macrophages acquire distinct transcriptomes prior to demyelination in multiple sclerosisAnneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Microglia and meningeal macrophages depletion delay the onset of experimental autoimmune encephalomyelitisAlejandro Montilla, Alazne Zabala, Marco Er-Lukowiak, Björn Rissiek, Tim Ullrich Magnus, Noelia Rodríguez-Iglesias, Amanda Sierra, Carlos Matute, Marı́a Domercq · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Intraperitoneal transfer of wild-type bone marrow cells in the Csf1r knockout rat repopulates resident tissue macrophages without contributing to monocytopoiesisAnuj Sehgal, Dylan Carter‐Cusack, Sahar Keshvari, Omkar L. Patkar, Stephen Huang, KIM M. SUMMERS, David Arthur Hume, Katharine M. Irvine · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- A novel glia-immune humanized mouse model for investigating neuroimmune mechanisms in CNS HIV infection and diverse neurological disordersShallu Tomer, Lin Pan, Jeffrey S. Harding, Valerie K. Rezek, Mitchell C. Krawczyk, Ethan Cook, Nandita Kedia, Li Wang, Jonathan Le, Christopher Platt et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- GPCR-targeted imaging and manipulation of homeostatic microglia in living systemsSwathi Vanaja Chandrasekharan, Payal Chaubey, Sunny Khandelwal, Raghavender Medishetti, Sushreeta Chakraborty, Shruthi Rajaram, Kavya Jayakumar, Pikaso Latua, Rythem Goyal, R Gopalakrishna et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Mesolimbic microglia display regionally distinct developmental trajectoriesKT Hope, IA Hawes, Antonello Bonci, Lindsay M. De Biase · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Microglia: A Critical Cell for NeurodevelopmentChristopher A. McPherson, Gaylia Jean Harry · 2021 · Springer eBooks
- Pathogen Invasion Reveals the Differential Plasticity and Fate of Resident and Recruited Brain Macrophages During the Onset and Resolution of DiseaseKaren De Vlaminck, Hannah Van Hove, Daliya Kancheva, Isabelle Scheyltjens, Ana Rita Pombo Antunes, Lauren Deneyer, Jonathan Bastos, Juliana Fabiani Miranda, Ruiyao Cai, Luc Bouwens et al. · 2021 · SSRN Electronic Journal
- Faculty Opinions recommendation of Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia.David H. Rowitch · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Influencing identityKatherine Whalley · 2018 · Nature reviews. Neuroscience
- Faculty Opinions recommendation of CD22 blockade restores homeostatic microglial phagocytosis in ageing brains.Sakae Tanaka · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- Transcriptome-guided optimization of in vitro culture conditions to study microglia in health and diseaseRaissa Timmerman · 2022
- Immunotherapy for Primary Cancers of Central Nervous SystemSeyed Farzad Maroufi, Esmaeil Mohammadi, Mohamad Namvar, Arad Iranmehr, Nima Rezaei, Sara Hanaei · 2023 · Springer eBooks
- The roles and findings of microglia in brain homeostasisLarissa Rodrigues Assunção, Felipe Gomes Boaventura, Amábile Castro da Silva, Hísllani Thauanni dos Santos Tomazini, Mayumi Cavalcante Hashiguchi, Emanuele Janoca Franca · 2023 · Brazilian Journal of Development
- Transplanted Astrocytes Show Functional Flexibility in the Recipient BrainPaul W. Frazel, Priya Prakash · 2023 · Journal of Neuroscience
- Secondary microglia formation center in the human fetal brainChenyun Song, Xinyu Chen, Rong Ji, Yang Liu, Ling Zhang, Lu Gao, Qizhi He, Lixiang Ma, Hexige Saiyin · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Additional file 3 of The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progressionBowen Ni, Guanglong Huang, Runwei Yang, Ziyu Wang, Haimin Song, Kaishu Li, Zhang, Yunxiao, Kezhi Wu, Guangwei Shi, Xiran Wang et al. · 2023 · Figshare
- Additional file 2 of The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progressionBowen Ni, Guanglong Huang, Runwei Yang, Ziyu Wang, Haimin Song, Kaishu Li, Zhang, Yunxiao, Kezhi Wu, Guangwei Shi, Xiran Wang et al. · 2023 · Figshare
- Microglia in multiple sclerosisKatharina Borst, Marco Prinz · 2024 · Elsevier eBooks
- Research progress of immune cell therapy for spinal cord injuryShuai-Yu Zhu · 2024 · New discovery.
- Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathologyKelsey Marie Nemec, Genevieve Uy, V Sai Chaluvadi, Freddy S Purnell, Bilal Elfayoumi, Carleigh A. O’Brien, William H. Aisenberg, Sonia I Lombroso, Xinfeng Guo, Niklas Blank et al. · 2025 · eLife
- Divergent Effects of APOE3 and APOE4 Human Astrocytes on Key Alzheimer’s Disease Hallmarks in Chimeric MiceJoan Cruz-Sesé, Marta Miron-Alcala, María Alfonso-Triguero, Jon Olalde, Leire Ruiz, Nuria Galbis-Gramage, Lorea Cortes, Laura Escobar, Pranav Preman, An Snellinx et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Orchestrating the neuroglial compartment: Ontogeny and developmental interaction of astrocytes, oligodendrocytes, and microgliaImke M. E. Schuurmans, Annika Mordelt, Lot D. de Witte · 2025 · Handbook of clinical neurology
- A restarted life: Resetting microglia innate immune memoryFangyuan Cheng, Bo Yan, Fanglian Chen, Ping Lei · 2025 · Neuroscience & Biobehavioral Reviews
- Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi-Goutières Syndrome neuropathologyKelsey Marie Nemec, Genevieve Uy, V Sai Chaluvadi, Freddy S Purnell, Bilal Elfayoumi, Leila Byerly, Micaela L. O’Reilly, Carleigh A. O’Brien, William H. Aisenberg, Sonia I Lombroso et al. · 2025 · eLife
- Immunotherapy for Primary Cancers of Central Nervous SystemSeyed Farzad Maroufi, Esmaeil Mohammadi, Mohamad Namvar, Arad Iranmehr, Nima Rezaei, Sara Hanaei · 2025 · Springer eBooks
- Microglia integrated neural spheroids enable neuroinflammatory responses and correct network dysfunction induced by alpha-synuclein mutationMarc Ferrer, Jiajing Zhang, Yi Wei Lim, Angelica Medina, Yu‐Chi Chen, Martin Carrasco Carvajal, Emily M. Lee · 2025 · Research Square
- Additional file 10 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 6 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsLien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Van Hove, Hannah, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Moons, Lieve et al. · 2023 · Figshare
- Additional file 12 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 2 of Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matterAnneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling et al. · 2022 · Figshare
- Additional file 4 of Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matterAnneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling et al. · 2022 · Figshare
- Additional file 1 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 1 of Sex- and region-biased depletion of microglia/macrophages attenuates CLN1 disease in miceKristina Berve, West, Brian L., Rudolf Martini, Janos Groh · 2020 · Figshare
- Additional file 2 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Markus J. Hofer, King, Nicholas J. C. · 2021 · Figshare
- Additional file 5 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 4 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 11 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 3 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Markus J. Hofer, King, Nicholas J. C. · 2021 · Figshare
- Additional file 1 of Effects of long-term and brain-wide colonization of peripheral bone marrow-derived myeloid cells in the CNSLindsay A. Hohsfield, Allison R. Najafi, Yasamine Ghorbanian, Neelakshi Soni, Edna E. Hingco, Kim, Sung Jin, Ayer Darling Jue, Swarup, Vivek, Mathew A. Inlay, Kim N. Green · 2020 · Figshare
- Additional file 9 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Markus J. Hofer, King, Nicholas J. C. · 2021 · Figshare
- Additional file 3 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsLien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Moons, Lieve et al. · 2023 · Figshare
- Additional file 4 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsLien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Moons, Lieve et al. · 2023 · Figshare
- Additional file 5 of Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matterAnneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling et al. · 2022 · Figshare
- Additional file 3 of Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matterAnneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling et al. · 2022 · Figshare
- Additional file 1 of Brain macrophages acquire distinct transcriptomes in multiple sclerosis lesions and normal appearing white matterAnneke Miedema, Emma Gerrits, Nieske Brouwer, Qiong Jiang, Laura Kracht, Michel Meijer, Erik Nutma, Regina M. B. Peferoen-Baert, Anna T. E. Pijnacker, Evelyn M. Wesseling et al. · 2022 · Figshare
- Additional file 7 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsLien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Moons, Lieve et al. · 2023 · Figshare
- Additional file 7 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Hofer, Markus J., King, Nicholas J. C. · 2021 · Figshare
- Additional file 8 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Markus J. Hofer, King, Nicholas J. C. · 2021 · Figshare
- Additional file 6 of High-parameter cytometry unmasks microglial cell spatio-temporal response kinetics in severe neuroinflammatory diseaseSpiteri, Alanna G., Terry, Rachel L., Claire L. Wishart, Ashhurst, Thomas M., Campbell, Iain L., Markus J. Hofer, King, Nicholas J. C. · 2021 · Figshare
- Additional file 1 of The short isoform of MS4A7 is a novel player in glioblastoma microenvironment, M2 macrophage polarization, and tumor progressionBowen Ni, Huang, Guanglong, Runwei Yang, Wang, Ziyu, Haimin Song, Li, Kaishu, Zhang, Yunxiao, Kezhi Wu, Shi, Guangwei, Wang, Xiran et al. · 2023 · Figshare
- Additional file 1 of Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammationPedram Honarpisheh, Juneyoung Lee, Anik Banerjee, Blasco-Conesa, Maria P., Parisa Honarpisheh, John d’Aigle, Mamun, Abdullah A., Ritzel, Rodney M., Chauhan, Anjali, Bhanu Priya Ganesh et al. · 2020 · Figshare
- Additional file 5 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsLien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Van Hove, Hannah, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Moons, Lieve et al. · 2023 · Figshare
- Additional file 1 of Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsLien Andries, Daliya Kancheva, Luca Masin, Isabelle Scheyltjens, Hannah Van Hove, Karen De Vlaminck, Steven Bergmans, Marie Claes, Lies De Groef, Moons, Lieve et al. · 2023 · Figshare
- Additional file 2 of Potential caveats of putative microglia-specific markers for assessment of age-related cerebrovascular neuroinflammationPedram Honarpisheh, Lee, Juneyoung, Anik Banerjee, Blasco-Conesa, Maria P., Parisa Honarpisheh, John d’Aigle, Mamun, Abdullah A., Ritzel, Rodney M., Anjali Chauhan, Bhanu Priya Ganesh et al. · 2020 · Figshare
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- Implication des macrophages périphériques dans la Sclérose latérale AmyotrophiqueAude Chiot · 2018 · theses.fr (ABES)
- Macrophage activation profiles of multiple sclerosis patientsJennifer Fransson · 2019 · theses.fr (ABES)
- Diversité des macrophages dans un modèle murin de stéatohépatite non alcooliqueSophie Tran · 2019 · theses.fr (ABES)
- Microglia in health and CNS disease: Learning from animal modelsHongli Ma, Yu Luo · 2026 · Journal of Cerebral Blood Flow & Metabolism
- Blood endothelial cells control the homeostasis of non-classical monocytesGuilhem R. Thierry · 2021 · theses.fr (ABES)
- Mechanisms controlling microglial colonization of the forebrainCécile Bridlance · 2023 · theses.fr (ABES)
- Caractérisation des bases moléculaires et cellulaires de la reprogrammation pro-inflammatoire des macrophages induites par les radiations ionisantesAli Mostefa Kara · 2022 · theses.fr (ABES)