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Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

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The Cellular Phase of Alzheimer’s Disease

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Neuronal excitation/inhibition imbalance: core element of a translational perspective on Alzheimer pathophysiology

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Alzheimer’s disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression

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Targeting neuroinflammation in Alzheimer’s disease: from mechanisms to clinical applications

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Connectome-based modelling of neurodegenerative diseases: towards precision medicine and mechanistic insight

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Amyloid-β: a potential link between epilepsy and cognitive decline

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Amyloid induced hyperexcitability in default mode network drives medial temporal hyperactivity and early tau accumulation

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Altered excitatory and inhibitory neuronal subpopulation parameters are distinctly associated with tau and amyloid in Alzheimer’s disease

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The aging mouse brain: cognition, connectivity and calcium

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Moving beyond amyloid and tau to capture the biological heterogeneity of Alzheimer’s disease

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GSK3: A potential target and pending issues for treatment of Alzheimer's disease

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Passive anti-amyloid β immunotherapy in Alzheimer's disease—opportunities and challenges

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Modulation of Brain Hyperexcitability: Potential New Therapeutic Approaches in Alzheimer’s Disease

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Epilepsy and epileptiform activity in late-onset Alzheimer disease: clinical and pathophysiological advances, gaps and conundrums

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Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer’s disease

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Resting-state oscillations reveal disturbed excitation–inhibition ratio in Alzheimer’s disease patients

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Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

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An Unbalanced Synaptic Transmission: Cause or Consequence of the Amyloid Oligomers Neurotoxicity?

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The Alzheimer’s disease risk gene BIN1 regulates activity-dependent gene expression in human-induced glutamatergic neurons

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The Interplay Between Beta-Amyloid 1–42 (Aβ1–42)-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral Deficits

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Predicting brain age from functional connectivity in symptomatic and preclinical Alzheimer disease

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The AppNL-G-F mouse retina is a site for preclinical Alzheimer’s disease diagnosis and research

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Selective suppression of oligodendrocyte-derived amyloid beta rescues neuronal dysfunction in Alzheimer’s disease

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Cerebral hyperactivation across the Alzheimer’s disease pathological cascade

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Hippocampal hyperactivity in a rat model of Alzheimer’s disease

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Combining aperiodic 1/f slopes and brain simulation: An EEG/MEG proxy marker of excitation/inhibition imbalance in Alzheimer's disease

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Modulating adult neurogenesis affects synaptic plasticity and cognitive functions in mouse models of Alzheimer's disease

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Functional Neurophysiological Biomarkers of Early-Stage Alzheimer’s Disease: A Perspective of Network Hyperexcitability in Disease Progression

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DecGAN: Decoupling Generative Adversarial Network for Detecting Abnormal Neural Circuits in Alzheimer's Disease

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Alzheimer’s disease and sleep disorders: A bidirectional relationship

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Crosstalk between bone and brain in Alzheimer's disease: Mechanisms, applications, and perspectives

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Network control through coordinated inhibition

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Mechanisms Involved in Epileptogenesis in Alzheimer’s Disease and Their Therapeutic Implications

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Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons

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Association of Seizure Foci and Location of Tau and Amyloid Deposition and Brain Atrophy in Patients With Alzheimer Disease and Seizures

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A multi-scale model explains oscillatory slowing and neuronal hyperactivity in Alzheimer’s disease

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Probing neural circuit mechanisms in Alzheimer’s disease using novel technologies

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Reduced synchrony in alpha oscillations during life predicts post mortem neurofibrillary tangle density in early‐onset and atypical Alzheimer's disease

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Hippocampal neural circuit connectivity alterations in an Alzheimer's disease mouse model revealed by monosynaptic rabies virus tracing

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Alzheimer’s disease and epilepsy: An increasingly recognized comorbidity

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Levetiracetam Treatment Normalizes Levels of Presynaptic Endocytosis Machinery and Restores Nonamyloidogenic APP Processing in App Knock-in Mice

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MDGA1 negatively regulates amyloid precursor protein–mediated synapse inhibition in the hippocampus

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On the relationships between epilepsy, sleep, and Alzheimer’s disease: A narrative review

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Neuronally differentiated macula densa cells regulate tissue remodeling and regeneration in the kidney

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Spatial coding defects of hippocampal neural ensemble calcium activities in the triple-transgenic Alzheimer's disease mouse model

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Alteration of Neural Pathways and Its Implications in Alzheimer’s Disease

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Hippocampal Connectivity with Retrosplenial Cortex is Linked to Neocortical Tau Accumulation and Memory Function

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Role of Senescent Astrocytes in Health and Disease

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Impairment of entorhinal cortex network activity in Alzheimer’s disease

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Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease

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Degenerate mapping of environmental location presages deficits in object-location encoding and memory in the 5xFAD mouse model for Alzheimer's disease

Zhang, H., Chen, L., Johnston, K. G., Crapser, J. D., Green, K. N., Ha, N. M.-L., Tenner, A. J., Holmes, T. C., Nitz, D. A., & Xu, X. (2022) · Neurobiology of Disease · doi:10.1016/j.nbd.2022.105939 · Cited by 25

Neuroprotection and Mechanism of Gas-miR36-5p from Gastrodia elata in an Alzheimer’s Disease Model by Regulating Glycogen Synthase Kinase-3β

Lu, Z., Fu, J., Wu, G., Yang, Z., Wu, X., Wang, D., You, Z., Nie, Z., & Sheng, Q. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242417295 · Cited by 23

Progressive excitability changes in the medial entorhinal cortex in the 3xTg mouse model of Alzheimer’s disease pathology

Chen, L., Christenson Wick, Z., Vetere, L. M., Vaughan, N., Jurkowski, A., Galas, A., Diego, K. S., Philipsberg, P. A., Soler, I., Feng, Y., et al. (2023) · The Journal of Neuroscience · doi:10.1523/jneurosci.1204-23.2023 · Cited by 21

Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models

Das, M., Mao, W., Shao, E., Tamhankar, S., Yu, G.-Q., Yu, X., Ho, K., Wang, X., Wang, J., & Mucke, L. (2021) · iScience · doi:10.1016/j.isci.2021.103245 · Cited by 21

Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo

Papanikolaou, A., Graykowski, D. R., Lee, B. I., Yang, M., Ellingford, R. A., Zünkler, J., Bond, S. A., Rowland, J. M., Rajani, R. M., Harris, S., et al. (2025) · Neuron · doi:10.1016/j.neuron.2025.04.010 · Cited by 23

Does Alzheimer's disease stem in the gastrointestinal system?

Khodabakhsh, P., Bazrgar, M., Dargahi, L., Mohagheghi, F., Taei, A. A., Parvardeh, S., & Ahmadiani, A. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120088 · Cited by 21

Aη-α and Aη-β peptides impair LTP ex vivo within the low nanomolar range and impact neuronal activity in vivo

Mensch, M., Dunot, J., Yishan, S. M., Harris, S., Blistein, A., Avdiu, A., Pousinha, P. A., Giudici, C., Busche, M. A., Jedlička, P., et al. (2021) · Alzheimer s Research & Therapy · doi:10.1186/s13195-021-00860-1 · Cited by 24

Cerebrospinal fluid proteomic profiling of individuals with mild cognitive impairment and suspected non‐Alzheimer's disease pathophysiology

Delvenne, A., Gobom, J., Tijms, B. M., Bos, I., Reus, L. M., Dobričić, V., ten Kate, M., Verhey, F. R. J., Ramakers, I. H. G. B., Scheltens, P., et al. (2022) · Alzheimer s & Dementia · doi:10.1002/alz.12713 · Cited by 19

Morphological connectivity differences in Alzheimer's disease correlate with gene transcription and cell‐type

Yu, H., Ding, Y., Wei, Y., Dyrba, M., Wang, D., Kang, X., Xu, W., Zhao, K., Liu, Y., & Initiative, A. D. N. (2023) · Human Brain Mapping · doi:10.1002/hbm.26512 · Cited by 19

Neuronal hyperexcitability in the Tg2576 mouse model of Alzheimer's disease – the influence of sleep and noradrenergic transmission

Szabo, A. B., Cattaud, V., Bezzina, C., Dard, R. F., Sayegh, F. J. P., Gauzin, S., Lejards, C., Valton, L., Rampon, C., Verret, L., et al. (2022) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2022.11.017 · Cited by 18

Accelerated Aging Characterizes the Early Stage of Alzheimer’s Disease

Leparulo, A., Bisio, M., Redolfi, N., Pozzan, T., Vassanelli, S., & Fasolato, C. (2022) · Cells · doi:10.3390/cells11020238 · Cited by 17

Non-competitive AMPA glutamate receptors antagonism by perampanel as a strategy to counteract hippocampal hyper-excitability and cognitive deficits in cerebral amyloidosis

Bellingacci, L., Tallarico, M., Mancini, A., Megaro, A., Caro, C. D., Citraro, R., Sarro, G. D., Tozzi, A., Filippo, M. D., Sciaccaluga, M., et al. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109373 · Cited by 17

APPsα Rescues Tau-Induced Synaptic Pathology

Bold, C. S., Baltissen, D., Ludewig, S., Back, M. K., Just, J., Kilian, L., Erdinger, S., Banićević, M., Rehra, L., Almouhanna, F., et al. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.2200-21.2022 · Cited by 17

Activity disruption causes degeneration of entorhinal neurons in a mouse model of Alzheimer’s circuit dysfunction

Zhao, R., Grunke, S. D., Li, M.-H., Wood, C. A., Perez, G., Comstock, M., Singh, A. K., Park, K.-W., & Jankowsky, J. L. (2022) · eLife · doi:10.7554/elife.83813 · Cited by 16

Excessive/Aberrant and Maladaptive Synaptic Plasticity: A Hypothesis for the Pathogenesis of Alzheimer’s Disease

Kawabata, S. (2022) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2022.913693 · Cited by 16

Persistent ∆FosB expression limits recurrent seizure activity and provides neuroprotection in the dentate gyrus of APP mice

Stephens, G. S., Park, J. K., Eagle, A. L., You, J. C., Silva‐Pérez, M., Fu, C.-H., Choi, S., Romain, C. P. S., Sugimoto, C., Buffington, S. A., et al. (2024) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2024.102612 · Cited by 16

Associations between accelerated forgetting, amyloid deposition and brain atrophy in older adults

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Directly Reprogrammed Human Neurons to Understand Age‐Related Energy Metabolism Impairment and Mitochondrial Dysfunction in Healthy Aging and Neurodegeneration

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Transcriptomic alterations in APP/PS1 mice astrocytes lead to early postnatal axon initial segment structural changes

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CRISPR-based epigenetic editing of Gad1 improves synaptic inhibition and cognitive behavior in a Tauopathy mouse model

Wan, L., Zhong, P., Li, P. S., Ren, Y., Wang, W., Yu, M., Feng, H. Y., & Yan, Z. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.106826 · Cited by 14

Night Watch on the Titanic: Detecting Early Signs of Epileptogenesis in Alzheimer Disease

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Lysosomal Function and Axon Guidance: Is There a Meaningful Liaison?

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Excessive Alcohol Use as a Risk Factor for Alzheimer’s Disease: Epidemiological and Preclinical Evidence

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