Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease

Cited by (269)

Items 101–200 of 269

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2. Large-scale cerebrospinal fluid proteomic analysis in Alzheimer’s disease patients reveals five molecular subtypes with distinct genetic risk profiles
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3. Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics
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5. Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10 + 16 mutation
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6. Single-nucleus multi-omics identifies shared and distinct pathways in Pick’s and Alzheimer’s disease
   Zechuan Shi, Sudeshna Das, Samuel Morabito, Jennifer T. Stocksdale, Emily Miyoshi, Shushrruth Sai Srinivasan, Nora Emerson, Arshi Shahin, Negin Rahimzadeh, Zhenkun Cao et al. · 2025 · Science Advances
7. The past and present of therapeutic strategy for Alzheimer’s diseases: potential for stem cell therapy
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8. Early Alzheimer’s disease pathology in human cortex is associated with a transient phase of distinct cell states
   Vahid Gazestani, Tushar Kamath, Naeem M. Nadaf, S.J. Burris, Brendan Rooney, Antti Junkkari, Charles R. Vanderburg, Tuomas H. Rauramaa, Martine Therrien, Matthew Tegtmeyer et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
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10. Overview of Proteomic Analysis of Amyloid Plaques and Neurofibrillary Tangles in Alzheimer’s Disease
    Amber Grewal, Simran Raikundalia, Joseph Zaia, Manveen K. Sethi · 2025 · Biomolecules
11. A high-throughput, quantitative platform using 2D dissociated human cerebral organoids to model neuroinflammation in Alzheimer’s disease
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13. Discovery of 4-(Arylethynyl)piperidine Derivatives as Potent Nonsaccharide O-GlcNAcase Inhibitors for the Treatment of Alzheimer’s Disease
    Zihan Cheng, Nianying Shang, Xiaoyu Wang, Yuying Kang, Jie Zhou, Jiaqi Lan, Jinping Hu, Ying Peng, Bailing Xu · 2024 · Journal of Medicinal Chemistry
14. Repetitive head impacts induce neuronal loss and neuroinflammation in young athletes
    Morgane L M D Butler, Nida Pervaiz, Kerry Breen, Samantha M. Calderazzo, Petra Ypsilantis, Yichen Wang, Julia Cammasola Breda, Sarah A. Mazzilli, Raymond Nicks, Elizabeth Spurlock et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
15. Integrative single-cell RNA sequencing and mendelian randomization analysis reveal the potential role of synaptic vesicle cycling-related genes in Alzheimer's disease
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16. Cellular specificity is key to deciphering epigenetic changes underlying Alzheimer's disease
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17. Implications of liquid-liquid phase separation and ferroptosis in Alzheimer's disease
    Fuwei Wang, Zihao Chen, Qiong Zhou, Qiang Sun, Nan Zheng, Ziwen Chen, Jiantao Lin, Baohong Li, Li Li · 2024 · Neuropharmacology
18. FAM19A5 Deficiency Mitigates the Aβ Plaque Burden and Improves Cognition in Mouse Models of Alzheimer's Disease
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19. Integration of Single-Cell and Spatial Transcriptomic Data Reveals Spatial Architecture and Potential Biomarkers in Alzheimer’s Disease
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20. Neuroimaging techniques, gene therapy, and gut microbiota: frontier advances and integrated applications in Alzheimer’s Disease research
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21. Monitoring the Dynamics of Alzheimer's Disease Biomarkers and the APOE –Tau Axis via Human Cerebral Organoids with Immuno‐SERS
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22. Molecular signatures of regional vulnerability to tauopathy in excitatory cortical neurons
    Diede W. M. Broekaart, Abhijeet Sharma, Aarthi Ramakrishnan, Anjalika Chongtham, Dorothee M. Günther, Saraswathi Subramaniyan, Minghui Wang, Vishwendra Patel, Bin Zhang, Lea T. Grinberg et al. · 2025 · Acta Neuropathologica
23. Cerebrospinal Fluid Erythrocyte Burden Amplifies the Impact of PTAU on Entorhinal Degeneration in Alzheimer’s Disease
    Rafail C. Christodoulou, Georgios Vamvouras, Vasileia Petrou, Platon S. Papageorgiou, Rafael Pitsillos, Ludwing Rivera, Evros K. Vassiliou, Sokratis G. Papageorgiou, Elena E. Solomou, Alzheimer’s Disease Neuroimaging Initiative · 2025 · Biomolecules
24. Systems biology approaches to unravel the molecular and genetic architecture of Alzheimer's disease and related tauopathies
    Miyoshi, Emily, Morabito, Samuel, Swarup, Vivek · 2021 · Neurobiology of Disease
25. Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics
    Kun Leng, Martin Kampmann · 2022 · Genome Medicine
26. Human disease-specific cell signatures in non-lesional tissue in Multiple Sclerosis detected by single-cell and spatial transcriptomics
    Matti Lam, Dylan I. Lee, Ivy M Kosater, Anthony Khairallah, Mariko F. Taga, Ya Zhang, Masashi Fujita, Sukriti Nag, David Alan Bennett, Philip L. De Jager et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
27. Biobanks and biomarkers: Their current and future role in biomedical research
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28. The m6A Modification in Neurodegenerative Disease: A Cellular Perspective
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29. Spatiotemporal transcriptomic profiling reveals upregulation of glycolysis pathway genes before overt tauopathy in the PS19 mouse model
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30. Synaptic proteome perturbations after maternal immune activation: Identification of embryonic and adult hippocampal changes
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31. Inhibition of FAM19A5 restores synaptic loss and improves cognitive function in mouse models of Alzheimer’s disease
    Hanbyul Kim, Sangjin Yoo, Hoyun Kwak, Shi‐Xun Ma, Ryunhee Kim, Minhyeok Lee, Nui Ha, Soonil Pyo, Soon-Gu Kwon, Eun-Ho Cho et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
32. Intra-cellular accumulation of amyloid is a marker of selective neuronal vulnerability in Alzheimer’s disease
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33. Interrogating DNA methylation associated with Lewy body pathology in a cross brain-region and multi-cohort study
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34. Brain network dynamics determine tau presence while regional vulnerability governs tau load in Alzheimer’s disease
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35. Saponins: A class of bioactive natural products with wide applications in human health
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36. Entwined processes in Alzheimer's disease: Brain cellular senescence and Alzheimer's disease pathology
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37. COMSE: analysis of single-cell RNA-seq data using community detection-based feature selection
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38. Local molecular and connectomic contributions of tau-related neurodegeneration
    Fardin Nabizadeh, Alzheimer’s Disease Neuroimaging Initiative, Michael Walter Weiner, Paul Aisen, Ronald Carl Petersen, Clifford R. Jack, William Jagust, John Q. Trojanowski, Arthur W. Toga, Laurel A. Beckett et al. · 2024 · GeroScience
39. Detection of molecular markers of ferroptosis in human Alzheimer's disease brains
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40. hiPSC-neurons recapitulate the subtype-specific cell intrinsic nature of susceptibility to neurodegenerative disease-relevant aggregation
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41. Uric Acid, the End-Product of Purine Metabolism, Mitigates Tau-Related Abnormalities: Comparison with DOT, a Non-Antibiotic Oxytetracycline Derivative
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42. Celebrating neuropathology's contributions to Alzheimer's Disease Research Centers
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43. Systems Medicine as a Strategy to Deal with Alzheimer’s Disease
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44. Neurons accumulate disease-specific somatic genomic changes across tau pathologic states in Alzheimer’s disease
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45. Activating Ras-MAPK pathway variants drive hippocampal clonal competition in human epilepsy
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46. Cutibacterium Acnes induces Alzheimer’s disease-like pathology in brains of wistar rats through structural changes associated with microtubules
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48. Downregulation of USP9X in the DG Region of the Hippocampus Leads to AD ‐Like Cognitive Dysfunction in Mice
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49. Increased nucleotide metabolism alleviates Alzheimer’s disease pathology
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50. Spinal cord Tau pathology induces tactile deficits and cognitive impairment in Alzheimer’s disease via dysregulation of CCK neurons
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51. Low Intensity Ultrasound-facilitated exosome delivery promotes hippocampal neurogenesis in Alzheimer's disease
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52. ACSS2 upregulation enhances neuronal resilience to aging and tau-associated neurodegeneration
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53. Mapping transcription factor functions in astrocytes using in vivo gain-of-function Perturb-seq
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54. Molecular Mechanisms Underlying Alzheimer’s Disease Pathogenesis: Comprehensive Overview
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55. Cell-type signatures of Alzheimer’s disease shared across population groups
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59. The Neurofibrillary Tangle Maturity Scale: A Novel Framework for Tangle Pathology Evaluation in Alzheimer’s Disease
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60. ATP6V1E1 and NDUFB5 identified as potential biomarkers for Alzheimer's disease through integrative analysis
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62. Translated retained intron 11 sequence confers pathological properties to Tau in Alzheimer’s disease
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65. Spatially Resolved Transcriptomics Reveals Gene Signatures Underlying the Vulnerability of Human Middle Temporal Gyrus in Alzheimer's Disease
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67. Distinct forms of amyloid-β moderate sleep duration through NAD + -linked redox metabolism in Alzheimer’s disease
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68. Cell type-specific associations with Alzheimer’s Disease conserved across racial and ethnic groups
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78. Inhibition of FAM19A5 reverses synaptic loss and cognitive decline in mouse models of Alzheimer’s disease
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