Molecular signatures underlying neurofibrillary tangle susceptibility in Alzheimer’s disease

Otero-Garcia, Marcos, Mahajani, Sameehan U., Wakhloo, Debia, Tang, Weijing, Xue, Yue-Qiang, Morabito, Samuel, Pan, Jie, Oberhauser, Jane +9 more·2022·Neuron

Cited by (269)

Items 201–269 of 269

  1. Neurogenesis-An Overview
    Blossom Samuel Affia · 2021 · Journal of Regenerative Biology and Medicine
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    Bernard Mulvey, Heena R. Divecha, Madhavi Tippani, Svitlana V. Bach, Rahul A. Bharadwaj, Ishbel Del Rosario, Sarah E. Maguire, Ryan A. Miller, Aaron J. Salisbury, Atharv Chandra et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  3. Identification of cell types associated with 14 brain phenotypes from more than 10 million single cells
    Tanya N. Phung, Sara L Seoane, Wei-Ping Li, Rachel M. Brouwer, Daniëlle Posthuma · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  4. Spatial Single-Cell Proteomics Reveals Molecular Trajectories Of Tangle-Bearing Neurons In Alzheimer’s Disease
    Martha S. Foiani, Mathieu Bourdenx, Kraller Lukas, Raja Nirujogi, Yiu Angela, Davies Hannah, Patel Saisha, Luiza-Simona Damoc, Ludovico Mitchener, Zane Jaunmuktane et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  5. Patient-derived tau-seeded human neuronal chimeras recapitulate mature Alzheimer’s tau pathology and uncover human-specific neuronal vulnerability
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  6. When less is more and when it isn’t: Microglial Spi1 and the limits of what we know
    Koldamova, Radosveta, Fitz, Nicholas F., Lefterov, Iliya · 2026 · Neuron
  7. Size matters - the impact of nucleus size on results from spatial transcriptomics
    Elyas Mohammadi, Katarzyna Chojnowska, Michał Bieńkowski, Anna Kostecka, Magdalena Koczkowska, Michal Aleksander Zmijewski, Marcin Jąkalski, Martin Ingelsson, Natalia H. Filipowicz, Paweł Olszewski et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  8. The Importance Of Human Induced Pluripotent Stem Cells In Neurodegenerative Disorders
    Wanyonyi Kennedy Mukhwana · 2022 · Journal of Regenerative Biology and Medicine
  9. Size Matters - The Impact of Nucleus Size on Results From Spatial Transcriptomics
    Elyas Mohammadi, Katarzyna Chojnowska, Michał Bieńkowski, Anna Kostecka, Magdalena Koczkowska, Michal Aleksander Zmijewski, Marcin Jąkalski, Martin Ingelsson, Natalia H. Filipowicz, Paweł Olszewski et al. · 2022 · SSRN Electronic Journal
  10. Neurodegeneration- Disease And Dementia
    Blossom Samuel Affia · 2021 · Journal of Biomedical and Allied Research
  11. Senescence and its Effect on Aging and Dementia
    Fariha Khaliq · 2022 · Journal of Regenerative Biology and Medicine
  12. Blocking the FAM19A5-LRRC4B complex enhances neurite growth and synapse assembly.
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  13. Ameliorative Effects of Methanolic extract of Erythrina variegate in Scopolamine-Induced Amnesic in Adult Zebrafish (Daniorerio) Model
    Saleem Ahmed et al. · 2023 · Egyptian Journal of Aquatic Biology and Fisheries
  14. Decoding complexity: the need to enhance precision and streamline spatial understanding in neuroscience
    Sameehan Uday Mahajani, Armita Salahi, Brenda Gonzalez, Charlotte Nelson, Frank Hsiung · 2024 · Neural Regeneration Research
  15. Inhibition of miR-4763-3p expression in the brains of AD-MCI mice activates the PI3K/mTOR/Bcl2 autophagy signaling pathway to reverse neuronal loss and ameliorate cognitive decline
    Wenxin Qi, Naijun Dong, Peiru WU, Wenjun Fu, Qian Liu, Xueqi Zhang, Hao Wu, Xirui He, Lingling Wu, Natalie Ward et al. · 2024 · Research Square
  16. Translational study on the role of genetic and prenatal risk factors in neurodevelopmental psychiatric disorders
    Anna Y. Yotova · 2024
  17. A Narrative Review of Alzheimer Dementia in African American and Hispanic Populations: The Health Care Provider's Role
    LaQuadria Symone Robinson, Kristin D. Ashley, Tiffany Brown Ervin, Tina Smith, Loretta T. Lee · 2024 · The Journal for Nurse Practitioners
  18. Imaging spatial transcriptomics reveals molecular patterns of vulnerability to pathology in a transgenic α-synucleinopathy model
    Liam Horan-Portelance, Michiyo Iba, Dominic J. Acri, Jesse Raphael Gibbs, Mark Cookson · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  19. Exploring the Potential of Malvidin and Echiodinin as Probable Antileishmanial Agents Through In Silico Analysis And In Vitro Efficacy
    Luis Daniel Goyzueta-Mamani, Daniela Pagliara Lage, Haruna Luz Barazorda-Ccahuana, Margot Paco-Chipana, Mayron Antonio Candia-Puma, Gonzalo Dávila-Del-Carpio, Alexsandro Sobreira Galdino, Ricardo Andrez Machado‐de‐Ávila, Rodolfo Cordeiro Giunchetti, E.L. D'Antonio et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  20. Systems genetic dissection of Alzheimer’s disease brain gene expression networks
    Pinghan Zhao, Omar El Fadel, Anh Le, Carl Grant Mangleburg, Justin S. Dhindsa, Timothy Wu, Jinghan Zhao, Meichen Huang, Bismark Kojo Amoh, Aditi Sai Marella et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  21. DNA damage and chromatin rearrangement in promoting neurodegeneration: role of hallmark proteins
    Angeline Julius, Suresh Malakondaiah, Raghu Babu Pothireddy · 2024 · Genome Instability & Disease
  22. Unraveling Alzheimer's disease heterogeneity:
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  23. An experimental framework for conjoint measures of olfaction, navigation, and motion as pre-clinical biomarkers of Alzheimer's disease
    Katarina Biljman, Illana Gozes, Jacqueline C. K. Lam, Victor O. K. Li · 2024 · Journal of Alzheimer s Disease Reports
  24. A Data Augmentation Method for Disease Diagnosis Based on Single Cell Omics Data
    Han Zhuang, Qinhu Zhang · 2025 · Communications in computer and information science
  25. The Therapeutic Role of Repetitive Transcranial Magnetic Stimulation in Alzheimer's Disease: A Comprehensive Review
    Yunqing Lai · 2025 · Advances in Engineering Technology Research
  26. scaLR: a low-resource deep neural network-based platform for single cell analysis and biomarker discovery
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  27. Protein kinase CK2α’ as a dual modulator of immune signaling and synaptic dysfunction in Tauopathy
    Angel White, Peter Gavrilyuk, Persephone Gu, Rafael Falcon Moya, Reid Thurston, Amal Fickak, Nicholas B Rozema, Prarthana Keshavaram, Scott Vermilyea, Riley Schlichte et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  28. Protein kinase CK2α′ as a dual modulator of neuroimmune signaling and synaptic dysfunction in tauopathy
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  29. O-GlcNAcylation: A molecular switch linking brain health to neurodegeneration
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  30. Neuro Omics: Translational Neuropathology Applications of Spatial Technologies From Nonclinical Models to Human Disease
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  31. Single-cell Spatial Transcriptional Profiling Uncovers Heterogeneous Cellular Responses to Pathogenic Tau in a Mouse Model of Neurodegeneration
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  32. Additional file 9 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  33. Additional file 14 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  34. Additional file 7 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  35. Additional file 10 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  36. Additional file 13 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  37. Additional file 15 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  38. Additional file 1 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  39. Additional file 8 of Abnormal accumulation of extracellular vesicles in hippocampal dystrophic axons and regulation by the primary cilia in Alzheimer’s disease
    Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Jung, Hyun Jin, Lee, Mi Suk, Choi, Seung Hee, Choe, Youngshik · 2024 · Figshare
  40. Introduction to Neurodegenerative Diseases
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  43. Regional correlates of tau pathology and synaptic function in primary age-related tauopathy
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  44. A unique compound 3c targets GSK-3β and metal ion, interferes with tau and metal dyshomeostasis, promotes neurite outgrowth, decreases Aβ accumulation and ABTS•+, and enhances zebrafish motility
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  49. Insights into the Comprehensive Role of Free Radicals in the Development of Alzheimer’s Disease: A Review
    Shireen Ansari, Ayushi Khali, Bhuwan Chandra Joshi, Sushmita Uniyal · 2026 · Physiological Mini Reviews
  50. FDA Approval of Donanemab‐azbt: A New Dawn in Alzheimer's Disease Treatment
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  51. Apolipoprotein E as a therapeutic target in Alzheimer's disease: A review of basic research and clinical evidence
    Arvinder Kaur, Shilpa Murthy, Bharath Kumar D.R., Gokulakrishnan S., Ugen Palmu Butiya Philantharopa, Chandrashekhar Narajji · 2026 · Elsevier eBooks
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  53. Single cell RNA sequencing and emerging transcriptomic technologies in Alzheimer’s disease cerebral organoids: a mini review
    Fazilah Maizatul Abdul Razak, Francis Yew Fu Tieng · 2026 · Molecular Brain
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  55. Proteomic comparison of hippocampal neurofibrillary tangles in PART, intermediate Alzheimer’s disease and advanced Alzheimer’s disease
    Manon Thierry, Dominique Leitner, Kaleah Balcomb, Tomas Kavanagh, Lauren Tang, Evgeny Kanshin, Christopher M. William, Derek Oakley, Bradley T. Hyman, Beatrix M. Ueberheide et al. · 2026 · Acta Neuropathologica
  56. Reduced expression of Brain Expressed X-linked genes in Alzheimer's disease
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    Hanyuan Zheng, Jie Zheng · 2026 · Trends in Pharmacological Sciences
  58. Transcriptomic Signatures of Microglial Phagocytosis Reveal Diagnostic Markers and Immune Landscape in Alzheimer's Disease
    Huimin Chang, Yun Liu, Xiaojun Yang, Yanqing Han · 2026 · The FASEB Journal
  59. Integrative transcriptomics identifies shared aging-associated inhibitory-neuron states and prioritizes RGL2 across postoperative delirium and Alzheimer’s disease
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  62. Molecular programs in human locus coeruleus link APOE and neuromelanin to Alzheimer’s vulnerability
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