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Potential reductions in ultra-processed food consumption substantially improve population cardiometabolic-related dietary nutrient profiles in eight countries
Abstract
Background and aims The negative effect on dietary nutrient profiles is the most obvious mechanism explaining the higher risk of cardiometabolic diseases associated with increased dietary share of UPF observed in large cohort studies. We estimate the proportion of diets with excessive energy density, excessive free sugars or saturated fat contents and insufficient fiber that could be avoided, if UPF consumption was reduced to levels among lowest consumers across eight countries, as well as the proportion of diets with multiple inadequacies. Methods and results Using nationally-representative cross-sectional surveys from Brazil (2008-09), Chile (2010), Colombia (2005), Mexico (2012), Australia (2011-12), the UK (2008-16), Canada (2015), and the US (2015-16), inadequate energy density (≥2.25 kcal/g) or contents of free sugars (>10% of total energy intake), saturated fats (>10% of total energy intake) and fiber ( Conclusions Lowering dietary contribution of UPF to levels among country-specific lowest consumers is a way to improve population cardiometabolic-related dietary nutrient profiles.
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Strong evidence already supports the plausibility of several mechanisms acting alone or in combination: gross nutrient imbalances; overeating driven by UPFs with high energy densities and hyper-palatability, as well as degraded food matrices and soft textures; reduced intake of healthy phytochemicals; and increased exposure to toxic compounds, endocrine disruptors, and harmful classes and mixtures
“Strong evidence already supports the plausibility of several mechanisms acting alone or in combination: gross nutrient imbalances; [46][47][48][49][50][51][52] overeating 46,55,56,58 driven by UPFs with high energy densities and hyper-palatability, 57 as well as degraded food matrices and soft textures; [58][59][60][61][62] reduced intake of healthy phytochemicals; 66,67 and increased exposure to”
From Ultra-processed foods and human health: the main thesis and the evidence (2025) · cites this paper as [47]
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Ultra-processed foods and human health: the main thesis and the evidence
Monteiro, C. A., Louzada, M. L., Steele-Martinez, E., Cannon, G., Andrade, G. C., Baker, P., Bes-Rastrollo, M., Bonaccio, M., Gearhardt, A. N., Khandpur, N., et al. (2025) · The Lancet · doi:10.1016/s0140-6736(25)01565-x · Cited by 339
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Metadata
- Authors
- Martinez Steele, E., Marrón Ponce, J. A., Cediel, G., Louzada, M. L. C., Khandpur, N., Machado, P., Moubarac, J.-C., Rauber, F., Corvalán, C., Levy, R. B., & Monteiro, C. A.
- Venue
- Nutrition, Metabolism and Cardiovascular Diseases
- Publisher
- Elsevier BV
- Published
- 2022-12
- Volume
- 32
- Issue
- 12
- Pages
- 2739-2750
- ISSN
- 0939-4753
- Cited by
- 32
- References
- 10
- Language
- en
- Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2015/14900–9, 2018/17972–9)
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