The DOI matches its Crossref record.
Nutritional status and food intake in nine patients with chronic low-limb ulcers and pressure ulcers: importance of oral supplements
Abstract
Objectives Chronic low-limb ulcers and pressure ulcers are a serious and costly issue. Malnutrition is a risk factor. Searching for intervention strategies in elderly patients referred for surgical closure of their ulcers, the trial aimed at investigating the micronutrient status, determining the food intake of such patients, and the role of oral liquid supplements. Methods Observational cohort study in 9 patients, starting 5 days prior to surgery until day 10 after surgery. Variables body mass index (BMI), food intake assessed using standardized meals (energy target 25 kcal/kg/day). Oral liquid supplements were provided between meals. Laboratory: blood count, plasma proteins, antioxidant status, vitamins, Fe, Se, and Zn. Results The patients were aged 71+/-10 y (mean+/-SD), with a BMI of 23.3+/-3.3. Baseline blood samples showed anemia and strong inflammation in 4 patients: albumin, retinol, and selenium were low; iron and zinc were very low. Food intake was largely variable and covered only about 76% (31-95%) of energy requirements. Breakfast provided 225+/-110, lunch 570+/-215, and dinner 405+/-150 kcal. Supplements were willingly consumed covering 35+/-12% of energy target. While vitamin supply was adequate, selenium and zinc requirements were not met. Conclusions Most patients with chronic skin ulcers suffered micronutrient status alterations, and borderline malnutrition. Meals did not cover energy requirements, while oral supplements covered basic micronutrient requirements and compensated for insufficient oral energy and protein intakes, justifying their use in hospitalized elderly patients.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In an observational study of older patients (71 ± 10 years) hospitalized for surgical repair of chronic pressure ulcers, intake from normal hospital meals covered only 76% of energy requirements.
“Results of an observational study in a small group of older patients (71 Æ 10 years) hospitalized for surgical repair of chronic pressure ulcers, showed that intake from normal hospital meals covered only 76% of patients' energy requirements.”
From Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group (2013) · cites this paper as [93]
Oral nutrition supplements were necessary to achieve both energy and protein requirements in those pressure ulcer patients.
“Oral nutrition supplements were necessary to achieve both energy and protein requirements.93”
From Evidence-Based Recommendations for Optimal Dietary Protein Intake in Older People: A Position Paper From the PROT-AGE Study Group (2013) · cites this paper as [93]
Citations
Cites
No references could be resolved yet.
Research works printed but not linked: 25
- Allman, 1995, Pressure ulcer risk factors among hospitalized patients with activity limitation, JAMA, 273, 865, 10.1001/jama.273.11.865 · DOI
- Lahmann, 2005, Prevalence of pressure ulcers in Germany, J Clin Nursing, 14, 165, 10.1111/j.1365-2702.2004.01037.x · DOI
- Nelzen, 1996, The prevalence of chronic low-limb ulceration has been underestimated. Results of a validated population questionnaire, Br J Surg, 83, 255, 10.1002/bjs.1800830235 · DOI · Paper page
- Bours, 2001, Prevalence, risk factors and prevention of pressure ulcers in Dutch intensive care units. Results of a cross-sectional survey, Intensive Care Med, 27, 1599, 10.1007/s001340101061 · DOI
- Martin, 1996, The use of antioxidants in healing, Dermatol Surg, 22, 156, 10.1016/1076-0512(95)00466-1 · DOI
- Chandra, 1995, Nutrition and immunity in elderly in the elderly, Nutrition Review, 53
- Rojas, 1999, Patients with chronic leg ulcers show diminished levels of vitamins A and E, carotenes, and zinc, Dermatologic Surgery, 25, 601, 10.1046/j.1524-4725.1999.99074.x · DOI
- Girodon, 1999, Impact of trace elements and vitamin supplementation on immunity and infections in institutionalized elderly patients - A randomized controlled trial, Arch Intern Med, 159, 748, 10.1001/archinte.159.7.748 · DOI
- Beck, 2001, Food and nutritional care in hospitals, Clin Nutr, 20, 455, 10.1054/clnu.2001.0494 · DOI
- Kondrup, 2002, Incidence of nutritional risk and causes of inadequate nutritional care in hospitals, Clin Nutr, 21, 461, 10.1054/clnu.2002.0585 · DOI
- Bourdel-Marchasson, 2001, Nutritional intervention trials for preventing and treating pressure ulcer, Nutrition, 17, 155, 10.1016/S0899-9007(00)00539-6 · DOI
- Heinen, 2004, Venous leg ulcer patients, J Clin Nursing, 13, 355, 10.1046/j.1365-2702.2003.00887.x · DOI
- Levey, 2003, National kidney foundation practice guidelines for chronic kidney disease, Ann Intern Med, 139, 137, 10.7326/0003-4819-139-2-200307150-00013 · DOI · Paper page
- Williams, 2002, Effect of a specialized amino acid mixture on human collagen deposition, Ann Surg, 236, 369, 10.1097/00000658-200209000-00013 · DOI
- Steghens, 1997, Simultaneous measurement of seven carotenoids, retinol and a-tocopherol in serum by high performance liquid chromatography, J Chromatogr B, 694, 71, 10.1016/S0378-4347(97)00140-0 · DOI
- Spears, 1989, Zinc methionine for ruminants, J Anim Sci, 67, 835, 10.2527/jas1989.673835x · DOI
- Miller, 1993, A novel method for measuring antioxidant capacity and its application to monitoring antioxidant status in premature neonates, Clin Sci, 84, 407, 10.1042/cs0840407 · DOI
- Richard, 1992, Malondialdehyde kit evaluated for determining plasma and lipoprotein fractions that react with thiobarbituric acid, Clin Chem, 38, 704, 10.1093/clinchem/38.5.704 · DOI
- Thefeld, 1973, Normalwerte der Serumharnsaure in Abhangigkeit von Alter und Geschlecht mit einem neuen enzymatischen Harnsaurefarbtest, Dtsch Med Wochenschr, 98, 380, 10.1055/s-0028-1106819 · DOI
- Gunzler, 1974, An improved coupled test procedure for glutathione peroxidase (EC 1-11-1-9) in blood, Z Klin Chem Klin Biochem, 12, 444
- Thomas, 1997, The role of nutrition in prevention and healing of pressure ulcers, Clin Ger Med, 13, 497, 10.1016/S0749-0690(18)30156-3 · DOI
- Green, 1999, Nutritional intake in community patients with pressure ulcers, J Wound Care, 8, 325, 10.12968/jowc.1999.8.7.25900 · DOI
- Stratton, 1999, A critical systematic analysis of the use of oral nutritional supplements in the community, Clin Nutr, 12, 29
- Berger, 1998, Trace element supplementation modulates pulmonary infection rates after major burns, Am J Clin Nutr, 68, 365, 10.1093/ajcn/68.2.365 · DOI
- Henzel, 1970, Zinc concentrations within healing wounds, Arch Surg, 100, 349, 10.1001/archsurg.1970.01340220025005 · DOI
Cited by
Sorted by citations
Bauer, J., Biolo, G., Cederholm, T., Cesari, M., Cruz-Jentoft, A. J., Morley, J. E., Phillips, S., Sieber, C., Stehle, P., Teta, D., et al. (2013) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2013.05.021 · Cited by 2,553
Ellinger, S., & Stehle, P. (2009) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e328331a5b5 · Cited by 74
Metadata
- Authors
- Raffoul, W., Far, M. S., Cayeux, M.-C., & Berger, M. M.
- Affiliations
- Centre Hospitalier Universitaire Vaudois (CH)
- Corresponding author
- Berger, Mette M.
- Venue
- Nutrition
- Publisher
- Elsevier BV
- Published
- 2006-01
- Volume
- 22
- Issue
- 1
- Pages
- 82-88
- ISSN
- 0899-9007 (ISSN-L)
- OpenAlex
- W1991561206
- Cited by
- 75
- References
- 0
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 3 · 2023: 3 · 2022: 5 · 2021: 2 · 2020: 4 · 2019: 4 · 2018: 2 · 2017: 3 · 2016: 1 · 2014: 4 · 2013: 4 · 2012: 4
- FWCI
- 4.21
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Nutrition (publishedVersion)
- PubMed (publishedVersion)
- IRIS (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Nutrition and Health in Aging
- Health Sciences › Nursing › Nutrition and Dietetics › Clinical Nutrition and Gastroenterology
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutrition and Health Studies
- Keywords
- pressure ulcers, malnutrition, micronutrient status, dietary intake, energy requirements, selenium deficiency, zinc deficiency, iron deficiency, anemia, inflammation, elderly patients, surgical wound closure, plasma proteins
- MeSH terms
- Administration, Oral, Aged, Aged, 80 and over, Blood Chemical Analysis, Energy Intake, Pressure Ulcer, Dietary Proteins, Eating, Female, Food, Formulated, Hospitalization, Humans, Male, Middle Aged, Nutritional Requirements, Nutritional Status, Prospective Studies, Ulcer, Wound Healing, Cohort Studies, Geriatric Assessment, Body Mass Index, Treatment Outcome, Micronutrients, Dietary Supplements
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
