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Cited by 56Hernia repair and managementSurgical Sutures and Adhesivesbiodegradable polymer synthesis and properties

A review of recent developments of polypropylene surgical mesh for hernia repair

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Saha, Tanushree, Wang, Xin, Padhye, Rajiv, Houshyar, Shadi·2022·OpenNano
DOI 10.1016/j.onano.2022.100046
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Abstract

Mesh has been used as a superior option to suture for reinforcing the weak abdominal wall during hernia surgery. As a result, there have been many attempts to make this fibre-based mesh more suitable for the host body. Researchers have explored different materials, designs and manufacturing techniques to improve the commercially available surgical meshes. In addition, surface modification has been widely used to modify and develop different biomechanical properties of mesh implants. This review provides comprehensive information on the properties, existing problems, and recent mesh developments in terms of modification techniques and their evaluations, including protein anti-adsorption, cellular attachment, biocompatibility, and antimicrobial resistance of polypropylene (PP) mesh. The outlook for future directions has also been discussed.

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  • PP meshes used in hernia repairs are sometimes coated with oxidized regenerated cellulose or polylactic acid to prevent contact with delicate organs like the intestines, reducing the risk of post-surgical adhesions.

    “For example, PP meshes used in hernia repairs are sometimes coated with oxidized regenerated cellulose or polylactic acid (PLA) to prevent contact with delicate organs like the intestines, thereby reducing the risk of post-surgical adhesions [245].”

    From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [245]

    Section 5.5 describes an oxidized regenerated cellulose–PCL layer on PP mesh with anti-adhesion properties. Section 5.2 says PLA films can prevent direct contact between damaged tissues, but does not establish that the films coat PP mesh; it also does not identify the ORC layer as PLA. The review supports the general barrier and adhesion-reduction rationale, but not both coatings as described. (LLM, conf=0.86)

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Cited by

Sorted by citations

Authors
Saha, T., Wang, X., Padhye, R., & Houshyar, S.
Affiliations
  • Dhaka University of Engineering & Technology (BD)
  • RMIT University (AU)
Corresponding author
  • Saha, Tanushree
  • Houshyar, Shadi
ORCID
Venue
OpenNano
Publisher
Elsevier BV
Published
2022-07
Volume
7
Pages
100046
ISSN
2352-9520 (ISSN-L)
DOI
10.1016/j.onano.2022.100046
OpenAlex
W4280520180
Cited by
56
References
0
Citations by year
2026: 11 · 2025: 19 · 2024: 17 · 2023: 9
FWCI
10.50
Type
journal article
Language
en
Open access
Licence
Locations
  • OpenNano (publishedVersion, cc-by-nc-nd)
  • RMIT Research Repository (RMIT University Library) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • Figshare (submittedVersion)
Funders
RMIT University
Topics
  • Health Sciences › Medicine › Surgery › Hernia repair and management
  • Health Sciences › Medicine › Surgery › Surgical Sutures and Adhesives
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
Keywords
hernia repair, surface modification, biocompatibility, antimicrobial resistance, cell attachment, tissue mechanics, abdominal wall reinforcement

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