The DOI matches its Crossref record; 238 of the 247 references it cites were found in a registry or an index.
Genetic mutations, molecular markers and future directions in research
Abstract
Recent molecular studies have described a number of abnormalities associated with the pathogenesis of thyroid carcinoma. These distinct molecular events are often associated with specific stages of tumor development and may serve as prognostic factors and therapeutic targets. A better understanding of the mechanisms involved in thyroid cancer pathogenesis, will hopefully help translate these discoveries to improved patient care.
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“Cellular dedifferentiation generally occurs in cases accompanied by more aggressive growth, recurrence, distant metastasis, and resistance to RAI [1, 8–10].”
From Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells (2017) · cites this paper as [8]
In the citing paper
“Nevertheless, approximately 5-15% of the cases are dedifferentiated papillary thyroid cancer (DePTC), which is associated with poor prognosis and high early-mortality [7–9].”
From Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells (2017) · cites this paper as [8]
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Prognostic biomarkers in thyroid cancer
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Metadata
- Authors
- Patel, K. N.
- Affiliations
- NYU Langone Health (US)
- Corresponding author
- Patel, Kepal N.
- ORCID
- Patel, Kepal N.
- Venue
- Oral Oncology
- Publisher
- Elsevier BV
- Published
- 2013-07
- Volume
- 49
- Issue
- 7
- Pages
- 711-721
- ISSN
- 1368-8375 (ISSN-L)
- OpenAlex
- W2072682157
- Cited by
- 6
- References
- 247
- Citations by year
- 2019: 1 · 2017: 1 · 2015: 1 · 2014: 3
- FWCI
- 0.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Oral Oncology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Keywords
- thyroid cancer, genetic mutations, molecular markers, carcinogenesis, prognostic factors, therapeutic target
- MeSH terms
- Cell Differentiation, Humans, Mutation, Thyroid Neoplasms, Biomarkers, Tumor
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