The DOI matches its Crossref record; 238 of the 247 references it cites were found in a registry or an index.
Genetic mutations, molecular markers and future directions in research
Abstract
Recent molecular studies have described a number of abnormalities associated with the pathogenesis of thyroid carcinoma. These distinct molecular events are often associated with specific stages of tumor development and may serve as prognostic factors and therapeutic targets. A better understanding of the mechanisms involved in thyroid cancer pathogenesis, will hopefully help translate these discoveries to improved patient care.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Cellular dedifferentiation generally occurs in cases accompanied by more aggressive growth, recurrence, distant metastasis, and resistance to RAI [1, 8–10].”
From Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells (2017) · cites this paper as [8]
In the citing paper
“Nevertheless, approximately 5-15% of the cases are dedifferentiated papillary thyroid cancer (DePTC), which is associated with poor prognosis and high early-mortality [7–9].”
From Restoration of p53 using the novel MDM2-p53 antagonist APG115 suppresses dedifferentiated papillary thyroid cancer cells (2017) · cites this paper as [8]
Citations
Cites
Haugen, B. R., Alexander, E. K., Bible, K. C., Doherty, G. M., Mandel, S. J., Nikiforov, Y. E., Pacini, F., Randolph, G. W., Sawka, A. M., Schlumberger, M., et al. (2016) · Thyroid® · doi:10.1089/thy.2015.0020 · Cited by 16,535
Mutations of the BRAF gene in human cancer
Davies, H., Bignell, G. R., Cox, C., Stephens, P., Edkins, S., Clegg, S., Teague, J., Woffendin, H., Garnett, M. J., Bottomley, W., et al. (2002) · Nature · doi:10.1038/nature00766 · Cited by 10,674
DNA methylation patterns and epigenetic memory
Bird, A. (2002) · Genes & Development · doi:10.1101/gad.947102 · Cited by 7,124
Cooper, D. S., Doherty, G. M., Haugen, B. R., Kloos, R. T., Lee, S. L., Mandel, S. J., Mazzaferri, E. L., McIver, B., Pacini, F., Schlumberger, M., et al. (2009) · Thyroid · doi:10.1089/thy.2009.0110 · Cited by 6,707
Barbacid, M. (1987) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.56.070187.004023 · Cited by 3,885
Increasing Incidence of Thyroid Cancer in the United States, 1973-2002
Davies, L., & Welch, H. G. (2006) · JAMA · doi:10.1001/jama.295.18.2164 · Cited by 3,379
Liaw, D., Marsh, D. J., Li, J., Dahia, P. L. M., Wang, S. I., Zheng, Z., Bose, S., Call, K. M., Tsou, H. C., Peacoke, M., et al. (1997) · Nature Genetics · doi:10.1038/ng0597-64 · Cited by 2,067
The GDNF family: Signalling, biological functions and therapeutic value
Airaksinen, M. S., & Saarma, M. (2002) · Nature reviews. Neuroscience · doi:10.1038/nrn812 · Cited by 1,862
Kimura, E. T., Nikiforova, M. N., Zhu, Z., Knauf, J. A., Nikiforov, Y. E., & Fagin, J. A. (2003) · PubMed · Cited by 1,510
Epigenetic therapy of cancer: past, present and future
Yoo, C. B., & Jones, P. A. (2006) · Nature Reviews Drug Discovery · doi:10.1038/nrd1930 · Cited by 1,307
BRAF mutation in thyroid cancer
Xing, M. (2005) · Endocrine Related Cancer · doi:10.1677/erc.1.0978 · Cited by 1,293
The role of microRNA genes in papillary thyroid carcinoma
He, H., Jażdżewski, K., Li, W., Liyanarachchi, S., Nagy, R. S., Volinia, S., Calin, G. A., Liu, C., Franssila, K., Suster, S. M., et al. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0509603102 · Cited by 1,218
Preoperative Diagnosis of Benign Thyroid Nodules with Indeterminate Cytology
Alexander, E. K., Kennedy, G. C., Baloch, Z. W., Cibas, E. S., Chudova, D. I., Diggans, J., Friedman, L., Kloos, R. T., LiVolsi, V. A., Mandel, S. J., et al. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1203208 · Cited by 1,170
Nikiforova, M. N., Kimura, E. T., Gandhi, M., Biddinger, P. W., Knauf, J. A., Basolo, F., Zhu, Z., Giannini, R., Salvatore, G., Fusco, A., et al. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030838 · Cited by 1,036
Molecular genetics and diagnosis of thyroid cancer
Nikiforov, Y. E., & Nikiforova, M. N. (2011) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2011.142 · Cited by 1,012
BRAF Mutation Predicts a Poorer Clinical Prognosis for Papillary Thyroid Cancer
Xing, M., Westra, W. H., Tufano, R. P., Cohen, Y., Rosenbaum, E., Rhoden, K. J., Carson, K. A., Vasko, V. V., Ларін, О. С., Tallini, G., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0987 · Cited by 992
BRAF Mutation in Papillary Thyroid Carcinoma
Cohen, Y., Xing, M., Mambo, E., Guo, Z., Wu, G., Trink, B., Beller, U., Westra, W. H., Ladenson, P. W., & Sidransky, D. (2003) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/95.8.625 · Cited by 917
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
Kondo, T., Ezzat, S., & Asa, S. L. (2006) · Nature reviews. Cancer · doi:10.1038/nrc1836 · Cited by 889
Baloch, Z. W., LiVolsi, V. A., Syl, L., Rosaí, J., Merino, M. J., Randolph, G. W., Vielh, P. R., DeMay, R. M., Sidawy, M. K., & Frable, W. J. (2008) · Diagnostic Cytopathology · doi:10.1002/dc.20830 · Cited by 878
Nikiforov, Y. E., Ohori, N. P., Hodak, S. P., Carty, S. E., LeBeau, S. O., Ferris, R. L., Yip, L., Seethala, R. R., TUBLIN, M. E., Stang, M. T., et al. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1469 · Cited by 790
PAX8-PPAR γ 1 Fusion in Oncogene Human Thyroid Carcinoma
Kroll, T. G., Sarraf, P., Pecciarini, L., Chen, C., Mueller, E., Spiegelman, B. M., & Fletcher, J. A. (2000) · Science · doi:10.1126/science.289.5483.1357 · Cited by 780
Chang, F., Steelman, L. S., Lee, J. T., Shelton, J. G., Navolanic, P. M., Blalock, W. L., Franklin, R. A., & McCubrey, J. A. (2003) · Leukemia · doi:10.1038/sj.leu.2402945 · Cited by 738
The Raf/MEK/ERK pathway: new concepts of activation
Peyssonnaux, C., & Eychène, A. (2001) · Biology of the Cell · doi:10.1016/s0248-4900(01)01125-x · Cited by 734
Molecular Testing for Mutations in Improving the Fine-Needle Aspiration Diagnosis of Thyroid Nodules
Nikiforov, Y. E., Steward, D. L., Robinson-Smith, T. M., Haugen, B. R., Klopper, J. P., Zhu, Z., Fagin, J. A., Falciglia, M., Weber, K., & Nikiforova, M. N. (2009) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-0247 · Cited by 711
Nikiforova, M. N., Lynch, R. A., Biddinger, P. W., Alexander, E. K., Dorn, G. W., Tallini, G., Kroll, T. G., & Nikiforov, Y. E. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021907 · Cited by 711
BRAF mutations and RET/PTC rearrangements are alternative events in the etiopathogenesis of PTC
Soares, P., Trovisco, V., Rocha, A. S., Lima, J. P., Castro, P., Preto, A., Máximo, V., Botelho, T. O., Seruca, R., & Sobrinho-Simões, M. A. (2003) · Oncogene · doi:10.1038/sj.onc.1206706 · Cited by 669
Kebebew, E., Greenspan, F. S., Clark, O. H., Woeber, K. A., & McMillan, A. (2005) · Cancer · doi:10.1002/cncr.20936 · Cited by 668
Nikiforov, Y. E., Rowland, J. M., Bove, K. E., Monforte-Muñoz, H., & Fagin, J. A. (1997) · PubMed · Cited by 666
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas.
Fagin, J. A., MATSUO, K., Karmakar, A., Chen, D. L., Tang, S., & Koeffler, H. P. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116168 · Cited by 647
MicroRNA Expression Profiling of Thyroid Tumors: Biological Significance and Diagnostic Utility
Nikiforova, M. N., Tseng, G. C., Steward, D. L., Diorio, D., & Nikiforov, Y. E. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-2696 · Cited by 592
Clinical Implication of Hot SpotBRAFMutation, V599E, in Papillary Thyroid Cancers
Namba, H., Nakashima, M., Hayashi, T., Hayashida, N., Maeda, S., Rogounovitch, T., Ohtsuru, A., Saenko, V., Kanematsu, T., & Yamashita, S. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-030305 · Cited by 532
Ricarte‐Filho, J. C., Ryder, M. M., Chitale, D. A., Rivera, M., Heguy, A., Ladanyi, M., Janakiraman, M., Solit, D. B., Knauf, J. A., Tuttle, R. M., et al. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-0727 · Cited by 532
Elisei, R., Ugolini, C., Viola, D., Lupi, C., Biagini, A., Giannini, R., Romei, C., Miccoli, P., Pinchera, A., & Basolo, F. (2008) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2008-0607 · Cited by 528
MicroRNA deregulation in human thyroid papillary carcinomas
Pallante, P., Visone, R., Ferracin, M., Ferraro, A., Berlingieri, M. T., Troncone, G., Chiappetta, G., Liu, C., Santoro, M. M., Negrini, M., et al. (2006) · Endocrine Related Cancer · doi:10.1677/erc.1.01209 · Cited by 528
Adeniran, A., Zhu, Z., Gandhi, M., Steward, D. L., Fidler, J. P., Giordano, T. J., Biddinger, P. W., & Nikiforov, Y. E. (2006) · The American Journal of Surgical Pathology · doi:10.1097/01.pas.0000176432.73455.1b · Cited by 493
RET/PTC Rearrangement in Thyroid Tumors
Nikiforov, Y. E. (2002) · Endocrine Pathology · doi:10.1385/ep:13:1:03 · Cited by 491
The Prevalence and Prognostic Value of BRAF Mutation in Thyroid Cancer
Kebebew, E., Weng, J., Bauer, J. M., Ranvier, G. G. F., Clark, O. H., Duh, Q., Shibru, D., Bastian, B. C., & Griffin, A. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e318148563d · Cited by 481
Poorly differentiated (“insular”) thyroid carcinoma
Carcangiu, M. L., Zamp, G., & Rosaí, J. (1984) · The American Journal of Surgical Pathology · doi:10.1097/00000478-198409000-00005 · Cited by 473
Anaplastic Thyroid Carcinoma: A Study of 70 Cases
Carcangiu, M. L., Steeper, T. A., Zampi, G., & Rosaí, J. (1985) · American Journal of Clinical Pathology · doi:10.1093/ajcp/83.2.135 · Cited by 466
Proximity of Chromosomal Loci That Participate in Radiation-Induced Rearrangements in Human Cells
Nikiforova, M. N., Stringer, J. R., Blough, R. I., Medvedovic, M., Fagin, J. A., & Nikiforov, Y. E. (2000) · Science · doi:10.1126/science.290.5489.138 · Cited by 465
Oncogenic AKAP9-BRAF fusion is a novel mechanism of MAPK pathway activation in thyroid cancer
Ciampi, R., Knauf, J. A., Kerler, R., Gandhi, M., Zhu, Z., Nikiforova, M. N., Rabes, H. M., Fagin, J. A., & Nikiforov, Y. E. (2005) · Journal of Clinical Investigation · doi:10.1172/jci23237 · Cited by 459
Raf proteins and cancer: B-Raf is identified as a mutational target
Mercer, K., & Pritchard, C. A. (2003) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/s0304-419x(03)00016-7 · Cited by 455
High frequency of ras oncogene activation in all stages of human thyroid tumorigenesis.
Lemoine, N. R., Mayall, E. S., Wyllie, F. S., Williams, E. D., Goyns, M. H., Stringer, B. M. J., & Wynford‐Thomas, D. (1989) · PubMed · Cited by 417
Visone, R., Russo, L., Pallante, P., Martino, I. D., Ferraro, A., Leone, V., Borbone, E., Petrocca, F., Alder, H., Croce, C. M., et al. (2007) · Endocrine Related Cancer · doi:10.1677/erc-07-0129 · Cited by 417
Follicular variant of papillary thyroid carcinoma
Liu, J., Singh, B., Tallini, G., Carlson, D. L., Katabi, N., Shaha, A. R., Tuttle, R. M., & Ghossein, R. A. (2006) · Cancer · doi:10.1002/cncr.22138 · Cited by 416
Hou, P., Liu, D., Shan, Y., Hu, S., Studeman, K. D., Condouris, S., Wang, Y., Trink, A., El‐Naggar, A. K., Tallini, G., et al. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-1125 · Cited by 416
High prevalence of BRAF gene mutation in papillary thyroid carcinomas and thyroid tumor cell lines.
Xu, X., Quiros, R. M., Gattuso, P., Ain, K. B., & Prinz, R. A. (2003) · PubMed · Cited by 415
Knauf, J. A., Ma, X., Smith, E. P., Zhang, L., Mitsutake, N., Liao, X.-H., Refetoff, S., Nikiforov, Y. E., & Fagin, J. A. (2005) · Cancer Research · doi:10.1158/0008-5472.can-05-0047 · Cited by 414
Poorly Differentiated Insular Thyroid Carcinoma
Kuhel, W. I., Kutler, D. I., & Santos-Buch, C. A. (1998) · Acta Cytologica · doi:10.1159/000331983 · Cited by 401
BRAF Mutations in Papillary Thyroid Carcinomas Inhibit Genes Involved in Iodine Metabolism
Durante, C., Puxeddu, E., Ferretti, E., Morisi, R., Moretti, S., Bruno, R., Barbi, F., Avenia, N., Scipioni, A., Verrienti, A., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-2707 · Cited by 397
Lupi, C., Giannini, R., Ugolini, C., Proietti, A., Berti, P., Minuto, M. N., Materazzi, G., Elisei, R., Santoro, M., Miccoli, P., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1179 · Cited by 392
Specific microRNAs are downregulated in human thyroid anaplastic carcinomas
Visone, R., Pallante, P., Vecchione, A. M., Cirombella, R., Ferracin, M., Ferraro, A., Volinia, S., Coluzzi, S., Leone, V., Borbone, E., et al. (2007) · Oncogene · doi:10.1038/sj.onc.1210564 · Cited by 390
Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype.
Santoro, M., Carlomagno, F., HAY, I. D., Herrmann, M. A., Grieco, M., Melillo, R. M., Pierotti, M. A., Bongarzone, I., Porta, G., & Berger, N. (1992) · Journal of Clinical Investigation · doi:10.1172/jci115743 · Cited by 390
Rivera, M., Ricarte‐Filho, J. C., Knauf, J. A., Shaha, A. R., Tuttle, M. R., Fagin, J. A., & Ghossein, R. A. (2010) · Modern Pathology · doi:10.1038/modpathol.2010.112 · Cited by 387
Riesco‐Eizaguirre, G., Gutierrez‐Martinez, P., García‐Cabezas, M. Á., Nistal, M., & Santisteban, P. (2006) · Endocrine Related Cancer · doi:10.1677/erc.1.01119 · Cited by 372
Donghi, R., Longoni, A., Pilotti, S., Michieli, P., Porta, G., & Pierotti, M. A. (1993) · Journal of Clinical Investigation · doi:10.1172/jci116385 · Cited by 369
Rabes, H. M., Demidchik, E. P., Sidorow, J. D., Lengfelder, E., Beimfohr, C., Hoelzel, D., & Klugbauer, S. (2000) · PubMed · Cited by 367
ras Mutations Are Associated With Aggressive Tumor Phenotypes and Poor Prognosis in Thyroid Cancer
García‐Rostán, G., Zhao, H., Camp, R. L., Pollán, M., Herrero, A., Pardo, J. A., Wu, R., Carcangiu, M. L., Costa, J. C., & Tallini, G. (2003) · Journal of Clinical Oncology · doi:10.1200/jco.2003.10.130 · Cited by 366
BRAF mutations are associated with some histological types of papillary thyroid carcinoma
Trovisco, V., de Castro, I. V., Soares, P., Máximo, V., Silva, P., Magalhães, J., AIu, A., Matías‐Guiu, X., & Sobrinho-Simões, M. A. (2004) · The Journal of Pathology · doi:10.1002/path.1511 · Cited by 361
Point Mutations of Ras Oncogenes are an Early Event in Thyroid Tumorigenesis
Namba, H., Rubin, S. A., & Fagin, J. A. (1990) · Molecular Endocrinology · doi:10.1210/mend-4-10-1474 · Cited by 359
Ito, T., Seyama, T., Mizuno, T., Tsuyama, N., Hayashi, T., Hayashi, Y., Dohi, K., Nakamura, N., & Akiyama, M. (1992) · American Journal of Otolaryngology · doi:10.1016/0196-0709(92)90038-u · Cited by 350
PAX8-PPARγ Rearrangement in Thyroid Tumors
Nikiforova, M. N., Biddinger, P. W., Caudill, C. M., Kroll, T. G., & Nikiforov, Y. E. (2002) · The American Journal of Surgical Pathology · doi:10.1097/00000478-200208000-00006 · Cited by 347
Bounacer, A., Wicker, R., Caillou, B., Cailleux, A.-F., Sarasin, A. R., Schlumberger, M. J., & Suarez, H. G. (1997) · Oncogene · doi:10.1038/sj.onc.1200206 · Cited by 337
Mutation of the PIK3CA Gene in Anaplastic Thyroid Cancer
García‐Rostán, G., Costa, Â. M., Pereira‐Castro, I., Salvatore, G., Hernández, R., Hermsem, M. J. A., Herrero, A., Fusco, A., Cameselle‐Teijeiro, J., & Santoro, M. M. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-4259 · Cited by 336
Klugbauer, S., Lengfelder, E., Demidchik, E. P., & Hm, R. (1995) · PubMed · Cited by 316
Cantara, S., Capezzone, M., Marchisotta, S., Capuano, S., Busonero, G., Toti, P., Santo, A. D., Caruso, G., Carli, A. F., Brilli, L., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2103 · Cited by 315
Targeted expression of the ret/PTC1 oncogene induces papillary thyroid carcinomas
Jhiang, S. M., Sagartz, J. E., Tong, Q., Parker‐Thornburg, J., Capen, C. C., Cho, J. Y., Xing, S., & Ledent, C. A. (1996) · Endocrinology · doi:10.1210/endo.137.1.8536638 · Cited by 313
Vasko, V. V., Espinosa, A. V., Scouten, W. T., He, H., Auer, H., Liyanarachchi, S., Ларін, О. С., Savchenko, V., Francis, G. L., de la Chapelle, A., et al. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0610733104 · Cited by 311
Specific Pattern of RAS Oncogene Mutations in Follicular Thyroid Tumors
Vasko, V. V., Ferrand, M., Cristofaro, J. D., Carayon, P., Henry, J. F., & Micco, C. D. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021186 · Cited by 309
Genetic Alterations in the Phosphatidylinositol-3 Kinase/Akt Pathway in Thyroid Cancer
Xing, M. (2010) · Thyroid · doi:10.1089/thy.2010.1646 · Cited by 309
Molecular Diagnostics and Predictors in Thyroid Cancer
Nikiforova, M. N., & Nikiforov, Y. E. (2009) · Thyroid · doi:10.1089/thy.2009.0240 · Cited by 308
Expression of PAX8-PPARγ1 Rearrangements in Both Follicular Thyroid Carcinomas and Adenomas
Marques, A. R., Espadinha, C., Catarino, A. L., Moniz, S., Pereira, T., Sobrinho, L. G., & Leite, V. A. P. H. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.8.8756 · Cited by 305
Frequent mutation and nuclear localization of betacatenin in anaplastic thyroid carcinoma
Gineza, G. (1999) · Cancer Research · Cited by 303
Tallini, G., Santoro, M. M., Helie, M., Carlomagno, F., Salvatore, G., Chiappetta, G., Carcangiu, M. L., & Fusco, A. (1998) · PubMed · Cited by 302
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors.
Dahia, P. L. M., Marsh, D. J., Zheng, Z., Zedenius, J., Komminoth, P., Frisk, T., Wallin, G., Parsons, R. E., Longy, M., Larsson, C., et al. (1997) · PubMed · Cited by 297
A Limited Set of Human MicroRNA Is Deregulated in Follicular Thyroid Carcinoma
Weber, F., Teresi, R. E., Broelsch, C. E., Frilling, A., & Eng, C. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-0693 · Cited by 296
BRAF mutations in papillary carcinomas of the thyroid
Fukushima, T., Suzuki, S., Mashiko, M., Ohtake, T., Endo, Y., Takebayashi, Y., Sekikawa, K., Hagiwara, K., & Takenoshita, S. (2003) · Oncogene · doi:10.1038/sj.onc.1206739 · Cited by 294
Fugazzola, L., Pilotti, S., Pinchera, A., Vorontsova, T. V., Mondellini, P., Bongarzone, I., Greco, A., Astakhova, L. N., Butti, M. G., & Demidchik, E. P. (1995) · PubMed · Cited by 280
Molecular genetics of thyroid cancer: implications for diagnosis, treatment and prognosis
Nikiforova, M. N., & Nikiforov, Y. E. (2007) · Expert Review of Molecular Diagnostics · doi:10.1586/14737159.8.1.83 · Cited by 277
Riesco-Eizaguirre, G., Rodríguez, I., De la Vieja, A., Costamagna, E., Carrasco, N., Nistal, M., & Santisteban, P. (2009) · Cancer Research · doi:10.1158/0008-5472.can-09-1248 · Cited by 265
Presence of mutations in all three ras genes in human thyroid tumors.
Suarez, H. G., Ja, D. V., Severino, M. E., Caillou, B., Schlumberger, M. J., Tubiana, M., Parmentier, C., & Monier, R. (1990) · PubMed · Cited by 262
García-Rostán, G., Camp, R., Herrero, A., Carcangiu, M., Rimm, D., & Tallini, G. (2001) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64045-x · Cited by 257
Grob, J., Gouvernet, J., Aymar, D., Mostaque, A., Romano, M., Collet, A., Noe, M. C., Diconstanzo, M. P., & Bonerandi, J. J. (1990) · Cancer · doi:10.1002/1097-0142(19900715)66:2 · Cited by 257
Salvatore, G., Giannini, R., Faviana, P., Caleo, A., Migliaccio, I., Fagin, J. A., Nikiforov, Y. E., Troncone, G., Palombini, L., Basolo, F., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032221 · Cited by 257
The RET/PTC3 oncogene: metastatic solid-type papillary carcinomas in murine thyroids.
Powell, D. J., Russell, J. P., Nibu, K., Li, G., Rhee, E. N., Liao, M., Goldstein, M., Keane, W. M., Santoro, M. M., Fusco, A., et al. (1998) · PubMed · Cited by 255
Ohori, N. P., Nikiforova, M. N., Schoedel, K. E., LeBeau, S. O., Hodak, S. P., Seethala, R. R., Carty, S. E., Ogilvie, J. B., Yip, L., & Nikiforov, Y. E. (2010) · Cancer Cytopathology · doi:10.1002/cncy.20063 · Cited by 253
RET/PTC oncogene activation is an early event in thyroid carcinogenesis.
Viglietto, G., Chiappetta, G., Martínez-Tello, F. J., Fukunaga, F., Tallini, G., Rigopoulou, D., Visconti, R., Mastro, A., Santoro, M., & Fusco, A. (1995) · PubMed · Cited by 248
RET/PTC Rearrangements and BRAF Mutations in Thyroid Tumorigenesis
Ciampi, R., & Nikiforov, Y. E. (2006) · Endocrinology · doi:10.1210/en.2006-0921 · Cited by 243
Castro, P., Rebocho, A. P., Soares, R. J., Magalhães, J., Roque, L., Trovisco, V., de Castro, I. V., Cardoso-Oliveira, M., Fonseca, E., Soares, P., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-1336 · Cited by 238
Santoro, M., Chiappetta, G., Cerrato, A., Salvatore, D., Zhang, L., Manzo, G., Picone, A., Portella, G., Santelli, G., Vecchio, G., et al. (1996) · PubMed · Cited by 234
Nikiforov, Y. E. (2004) · Endocrine Pathology · doi:10.1385/ep:15:4:319 · Cited by 233
Thyroid cancer in thyroid nodules: Finding a needle in the haystack
Mazzaferri, E. L. (1992) · The American Journal of Medicine · doi:10.1016/0002-9343(92)90163-6 · Cited by 231
Mutations of the BRAF Gene in Papillary Thyroid Carcinoma in a Korean Population
Kim, K., Kang, D., Kim, S. H., Seong, I. O., & Kang, D. Y. (2004) · Yonsei Medical Journal · doi:10.3349/ymj.2004.45.5.818 · Cited by 229
Molecular Basis of Thyroid Cancer*
Farid, N. R., Shi, Y., & Zou, M. (1994) · Endocrine Reviews · doi:10.1210/edrv-15-2-202 · Cited by 226
RET Oncogene Activation in Papillary Thyroid Carcinoma
Tallini, G., Asa, S. L., & Fuller, G. N. (2001) · Advances in Anatomic Pathology · doi:10.1097/00125480-200111000-00005 · Cited by 224
Pierotti, M. A., Santoro, M. M., Jenkins, R. B., Sozzi, G., Bongarzone, I., Grieco, M., Monzini, N., Miozzo, M. R., Herrmann, M. A., & Fusco, A. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.5.1616 · Cited by 224
Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma.
Garcia-Rostan, G., Tallini, G., Herrero, A., D'Aquila, T. G., Carcangiu, M. L., & Rimm, D. L. (1999) · PubMed · Cited by 221
Prevalence of Ras mutations in thyroid neoplasia
Esapa, C. T., Johnson, S. J., Kendall‐Taylor, P., Lennard, T. W. J., & Harris, P. E. (1999) · Clinical Endocrinology · doi:10.1046/j.1365-2265.1999.00704.x · Cited by 220
Parwani, A. V. (2007) · Yearbook of Pathology and Laboratory Medicine · doi:10.1016/s1077-9108(08)70389-x · Cited by 219
Bongarzone, I., Butti, M. G., Coronelli, S., Borrello, M. G., Santoro, M., Mondellini, P., Pilotti, S., Fusco, A., Porta, G., & Pierotti, M. A. (1994) · PubMed · Cited by 215
MicroRNA analysis as a potential diagnostic tool for papillary thyroid carcinoma
Chen, Y., Kitabayashi, N., Zhou, X., Fahey, T. J., & Scognamiglio, T. (2008) · Modern Pathology · doi:10.1038/modpathol.2008.105 · Cited by 210
Anaplastic carcinoma of the thyroid
Lo, C., Lam, K.-Y., & Wan, K. Y. (1999) · The American Journal of Surgery · doi:10.1016/s0002-9610(99)00052-5 · Cited by 210
Cohen, Y., Rosenbaum, E., Clark, D. P., Zeiger, M. A., Umbricht, C. B., Tufano, R. P., Sidransky, D., & Westra, W. H. (2004) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-03-0273 · Cited by 209
Santarpia, L., El‐Naggar, A. K., Cote, G. J., Myers, J. N., & Sherman, S. I. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2007-1076 · Cited by 208
Prognostic utility of BRAF mutation in papillary thyroid cancer
Xing, M. (2009) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2009.10.012 · Cited by 208
Dwight, T., Thoppe, S. R., Foukakis, T., Lui, W., Wallin, G., Höög, A., Frisk, T., Larsson, C., & Zedenius, J. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021690 · Cited by 207
Zhu, Z., Ciampi, R., Nikiforova, M. N., Gandhi, M., & Nikiforov, Y. E. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1006 · Cited by 207
BRAF mutations in metastatic melanoma: a possible association with clinical outcome.
Kumar, R., Angelini, S., Czene, K., Sauroja, I., Hahka‐Kemppinen, M., Pyrhönen, S. O., & Hemminki, K. (2003) · PubMed · Cited by 205
Hu, S., Liu, D., Tufano, R. P., Carson, K. A., Rosenbaum, E., Cohen, Y., Holt, E. H., Kiseljak‐Vassiliades, K., Rhoden, K. J., Tolaney, S. M., et al. (2006) · International Journal of Cancer · doi:10.1002/ijc.22110 · Cited by 202
Liu, D., Hu, S., Hou, P., JIANG, D., Condouris, S., & Xing, M. (2007) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-06-1753 · Cited by 202
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway
Saavedra, H. I., Knauf, J., Shirokawa, J. M., Wang, J., Ouyang, B., Elisei, R., Stambrook, P., & Fagin, J. (2000) · Oncogene · doi:10.1038/sj.onc.1203723 · Cited by 195
Adenomatous polyposis: An association with carcinoma of the thyroid
Plail, R. O., Bussey, H. J. R., Glazer, G., & Thomson, J. P. S. (1987) · British journal of surgery · doi:10.1002/bjs.1800740517 · Cited by 194
Albores‐Saavedra, J., Henson, D. E., Glazer, E. S., & Schwartz, A. M. (2007) · Endocrine Pathology · doi:10.1007/s12022-007-0002-z · Cited by 192
Bongarzone, I., Fugazzola, L., Vigneri, P. G., Mariani, L., Mondellini, P., Pacini, F., Basolo, F., Pinchera, A., Pilotti, S., & Pierotti, M. A. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.5.8626874 · Cited by 190
Detection of the PAX8-PPARγ Fusion Oncogene in Both Follicular Thyroid Carcinomas and Adenomas
Cheung, L., Messina, M., Gill, A. J., Clarkson, A., Learoyd, D., Delbridge, L., Wentworth, J. M., Philips, J. N., Clifton-Bligh, R. J., & Robinson, B. G. (2003) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2002-021020 · Cited by 187
Moses, W., Weng, J., Sansano, I. G., Peng, M., Khanafshar, E., Ljung, B., Duh, Q., Clark, O. H., & Kebebew, E. (2010) · World Journal of Surgery · doi:10.1007/s00268-010-0720-0 · Cited by 184
Pathology and genetics of thyroid carcinoma
DeLellis, R. A. (2006) · Journal of Surgical Oncology · doi:10.1002/jso.20700 · Cited by 181
Cheung, C. C., Carydis, B., Ezzat, S., Bédard, Y. C., & Asa, S. L. (2001) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.86.5.7504 · Cited by 180
Bongarzone, I., Vigneri, P. G., Mariani, L., Collini, P., Pilotti, S., & Pierotti, M. A. (1998) · PubMed · Cited by 178
Gene Methylation in Thyroid Tumorigenesis
Xing, M. (2006) · Endocrinology · doi:10.1210/en.2006-0927 · Cited by 176
Cameselle‐Teijeiro, J., & Chan, J. K. C. (1999) · PubMed · Cited by 176
Begum, S., Rosenbaum, E., Henrique, R., Cohen, Y., Sidransky, D., & Westra, W. H. (2004) · Modern Pathology · doi:10.1038/modpathol.3800198 · Cited by 175
Knauf, J. A., Sartor, M. A., Medvedovic, M., Lundsmith, E. T., Ryder, M., Salzano, M., Nikiforov, Y. E., Giordano, T. J., Ghossein, R. A., & Fagin, J. A. (2011) · Oncogene · doi:10.1038/onc.2011.44 · Cited by 175
RasOncogene Mutations in Benign and Malignant Thyroid Neoplasms
Karga, H., Lee, J., Vickery, A. L., Thor, A. D., Gaz, R. D., & Jameson, J. L. (1991) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-73-4-832 · Cited by 175
Klugbauer, S., & Rabes, H. M. (1999) · Oncogene · doi:10.1038/sj.onc.1202824 · Cited by 172
Optimizing surgical treatment of papillary thyroid carcinoma associated with BRAF mutation
Yip, L., Nikiforova, M. N., Carty, S. E., Yim, J. H., Stang, M. T., TUBLIN, M. E., LeBeau, S. O., Hodak, S. P., Ogilvie, J. B., & Nikiforov, Y. E. (2009) · Surgery · doi:10.1016/j.surg.2009.09.011 · Cited by 165
Burgess, J. R., & Tucker, P. (2006) · Thyroid · doi:10.1089/thy.2006.16.47 · Cited by 165
Cost-Effectiveness of a Novel Molecular Test for Cytologically Indeterminate Thyroid Nodules
Li, H., Robinson, K. A., Anton, B., Saldanha, I. J., & Ladenson, P. W. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-0459 · Cited by 165
Stepwise Participation of p53 Gene Mutation During Dedifferentiation of Human Thyroid Carcinomas
Dobashi, Y., Sugimura, H., Sakamoto, A., Mernyei, M., Mori, M., Oyama, T., & Machinami, R. (1994) · Diagnostic Molecular Pathology · doi:10.1097/00019606-199403010-00003 · Cited by 163
Romei, C., Ciampi, R., Faviana, P., Agate, L., Molinaro, E., Bottici, V., Basolo, F., Miccoli, P., Pacini, F., Pinchera, A., et al. (2008) · Endocrine Related Cancer · doi:10.1677/erc-07-0130 · Cited by 160
On Trk for Retrograde Signaling
Miller, F. D., & Kaplan, D. R. (2001) · Neuron · doi:10.1016/s0896-6273(01)00529-3 · Cited by 158
PTEN Promoter Methylation in Sporadic Thyroid Carcinomas
Álvarez-Núñez, F., Bussaglia, E., Mauricio, D., Ybarra, J., Vilar, M., Lerma, E., de Leiva, A., & Matías‐Guiu, X. (2006) · Thyroid · doi:10.1089/thy.2006.16.17 · Cited by 156
Basolo, F., Pisaturo, F., Pollina, L. E., Fontanini, G., Elisei, R., Molinaro, E., Iacconi, P., Miccoli, P., & Pacini, F. (2000) · Thyroid · doi:10.1089/thy.2000.10.19 · Cited by 155
Kim, S. W., Lee, J. I., Kim, J., Ki, C., Oh, Y. L., Choi, Y., Shin, J. H., Kim, H. K., Jang, H. W., & Chung, J. H. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2795 · Cited by 154
Moretti, F., Farsetti, A., Soddu, S., Misiti, S., Crescenzi, M., Filetti, S., Andreoli, M., Sacchi, A., & Pontecorvi, A. (1997) · Oncogene · doi:10.1038/sj.onc.1200887 · Cited by 150
Frequent epigenetic silencing of the CpG island promoter of RASSF1A in thyroid carcinoma.
Schagdarsurengin, U., Gimm, O., Hoang‐Vu, C., Dralle, H., Pfeifer, G. P., & Dammann, R. (2002) · PubMed · Cited by 149
Duick, D. S., Klopper, J. P., Diggans, J., Friedman, L., Kennedy, G. C., Lanman, R. B., & McIver, B. (2012) · Thyroid · doi:10.1089/thy.2012.0180 · Cited by 148
Cost Impact of Molecular Testing for Indeterminate Thyroid Nodule Fine-Needle Aspiration Biopsies
Yip, L., Farris, C. A., Kabaker, A. S., Hodak, S. P., Nikiforova, M. N., McCoy, K. L., Stang, M. T., Smith, K. J., Nikiforov, Y. E., & Carty, S. E. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-3048 · Cited by 147
Pyrosequencing Analysis for Detection of a BRAFV600E Mutation in an FNAB Specimen of Thyroid Nodules
Kim, S. K., Kim, D., Han, H. S., Kim, W. S., Kim, S. J., Moon, W., Oh, S. Y., & Hwang, T. S. (2008) · Diagnostic Molecular Pathology · doi:10.1097/pdm.0b013e31815d059d · Cited by 146
Sugg, S. L., Zheng, L., Rosen, I. B., Freeman, J. L., Ezzat, S., & Asa, S. L. (1996) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.81.9.8784097 · Cited by 146
Bruni, P., Boccia, A. S., Baldassarre, G., Trapasso, F., Santoro, M., Chiappetta, G., Fusco, A., & Viglietto, G. (2000) · Oncogene · doi:10.1038/sj.onc.1203633 · Cited by 145
Xing, M., Cohen, Y., Mambo, E., Tallini, G., Udelsman, R., Ladenson, P. W., & Sidransky, D. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3242 · Cited by 143
p53 Gene Mutations Associated with Anaplastic Transformation of Human Thyroid Carcinomas
Nakamura, T., Yana, I., Kobayashi, T., Shin, E., Karakawa, K., Fujita, S., Miya, A., Mori, T., Nishisho, I., & Takai, S. (1992) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1992.tb02761.x · Cited by 138
Detection of the PTC/retTPC oncogene in human thyroid cancers.
Sm, J., Caruso, D. R., Gilmore, E., Ishizaka, Y., Tahira, T., Nagao, M., Chiu, I. M., & Mazzaferri, E. L. (1992) · PubMed · Cited by 138
Kim, S. K., Hwang, T. S., Yoo, Y. B., Han, H. S., Kim, D., Song, K., Lim, S. D., Kim, W. S., & Paik, N. S. (2011) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1082 · Cited by 137
Howell, G. M., Nikiforova, M. N., Carty, S. E., Armstrong, M. J., Hodak, S. P., Stang, M. T., McCoy, K. L., Nikiforov, Y. E., & Yip, L. (2012) · Annals of Surgical Oncology · doi:10.1245/s10434-012-2611-0 · Cited by 137
Nakata, T., Kitamura, Y., Shimizu, K., Tanaka, S., Fujimori, M., Yokoyama, S., Ito, K., & Emi, M. (1999) · Genes Chromosomes and Cancer · doi:10.1002/(sici)1098-2264(199906)25:2 · Cited by 134
Khoo, M. L. C., Beasley, N. J. P., Ezzat, S., Freeman, J. L., & Asa, S. L. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.4.8353 · Cited by 133
Unger, K., Zitzelsberger, H. F., Salvatore, G., Santoro, M. M., Ti, B., Braselmann, H., Kastner, P., Zurnadzhy, L., Tronko, N., Hutzler, P., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-031870 · Cited by 132
Detection of retTPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method.
Ishizaka, Y., Kobayashi, S. S., Ushijima, T., Hirohashi, S., Sugimura, T., & Nagao, M. (1991) · PubMed · Cited by 131
Gene rearrangement and Chernobyl related thyroid cancers
Santoro, M. M., Thomas, G. A. O., Vecchio, G., Williams, G. H., Fusco, A., Chiappetta, G., Pozcharskaya, V., Ti, B., Demidchik, E. P., Cherstvoy, E. D., et al. (2000) · British Journal of Cancer · doi:10.1054/bjoc.1999.0921 · Cited by 130
Phillips, G. L., Fay, J. W., Herzig, G. P., Herzig, R. H., Weiner, R. S., Wolff, S. N., Lazarus, H. M., Karanes, C., Ross, W. E., & Kramer, B. S. (1983) · Cancer · doi:10.1002/1097-0142(19831115)52:10 · Cited by 130
Fagin, J. A. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.5.0838 · Cited by 130
Klugbauer, S., Demidchik, E. P., Lengfelder, E., & Hm, R. (1998) · PubMed · Cited by 128
Quantitative Assessment of Promoter Methylation Profiles in Thyroid Neoplasms
Hoque, M. O., Rosenbaum, E., Westra, W. H., Xing, M., Ladenson, P. W., Zeiger, M. A., Sidransky, D., & Umbricht, C. B. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0313 · Cited by 127
Selective activation of ras oncogenes in follicular and undifferentiated thyroid carcinomas
Manenti, G., Pilotti, S., Re, F. C., Porta, G., & Pierotti, M. A. (1994) · European Journal of Cancer · doi:10.1016/0959-8049(94)90130-9 · Cited by 126
MicroRNA Expression Profiles in Thyroid Tumors
Nikiforova, M. N., Chiosea, S. I., & Nikiforov, Y. E. (2009) · Endocrine Pathology · doi:10.1007/s12022-009-9069-z · Cited by 125
N-ras mutation: an independent prognostic factor for aggressiveness of papillary thyroid carcinoma.
Hara, H., Fulton, N. C., YASHIRO, T., Ito, K., DeGroot, L. J., & Kaplan, E. L. (1994) · PubMed · Cited by 124
Vasko, V. V., Hu, S., Wu, G., Xing, J. C., Ларін, О. С., Savchenko, V., Trink, B., & Xing, M. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-2353 · Cited by 121
The Role of Cell Cycle Regulatory Protein, Cyclin D1, in the Progression of Thyroid Cancer
Wang, S., Lloyd, R. V., Hutzler, M., Safran, M., Patwardhan, N. A., & Khan, A. A. (2000) · Modern Pathology · doi:10.1038/modpathol.3880157 · Cited by 116
Predisposition to Neoplastic Transformation Caused by Gene Replacement of H- ras 1
Finney, R. E., & Bishop, J. M. (1993) · Science · doi:10.1126/science.8502998 · Cited by 116
Expression of PAX8-PPAR 1 Rearrangements in Both Follicular Thyroid Carcinomas and Adenomas
Marques, A. R. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.87.8.3947 · Cited by 110
H-Ras Protooncogene Mutations in Human Thyroid Neoplasms*
Namba, H., Gutman, R. A., MATSUO, K., Alvarez, A., & Fagin, J. A. (1990) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem-71-1-223 · Cited by 109
Cowden disease. Report of a family and review.
Longy, M., & Lacombe, D. (1996) · PubMed · Cited by 108
Role of ras mutation in the progression of thyroid carcinoma of follicular epithelial origin
Motoi, N., Sakamoto, A., Yamochi, T., Horiuchi, H., Motoi, T., & Machinami, R. (2000) · Pathology - Research and Practice · doi:10.1016/s0344-0338(00)80015-1 · Cited by 106
Loss of p53 Promotes Anaplasia and Local Invasion in ret/PTC1-Induced Thyroid Carcinomas
Perle, K. M. D. L., Jhiang, S. M., & Capen, C. C. (2000) · American Journal Of Pathology · doi:10.1016/s0002-9440(10)64577-4 · Cited by 106
Gupta, S. (2012) · Archives of Otolaryngology - Head and Neck Surgery · doi:10.1001/archoto.2011.1466 · Cited by 104
Cristofaro, J. D., Marcy, M., Vasko, V. V., Sebag, F. A., Fakhry, N., Wynford‐Thomas, D., & Micco, C. D. (2006) · Human Pathology · doi:10.1016/j.humpath.2006.01.030 · Cited by 102
Higher rate of BRAF mutation in papillary thyroid cancer over time
Mathur, A., Moses, W., Rahbari, R. M., Khanafshar, E., Duh, Q., Clark, O. H., & Kebebew, E. (2011) · Cancer · doi:10.1002/cncr.26072 · Cited by 100
A new BRAF gene mutation detected in a case of a solid variant of papillary thyroid carcinoma
Trovisco, V., Soares, P., Soares, R., Magalhães, J., Sá-Couto, P., & Sobrinho-Simões, M. A. (2005) · Human Pathology · doi:10.1016/j.humpath.2005.04.011 · Cited by 100
Prevalence of Activating ras Mutations in Morphologically Characterized Thyroid Nodules
Ezzat, S., Zheng, L., KOLENDA, J., SAFARIAN, A., Freeman, J. L., & Asa, S. L. (1996) · Thyroid · doi:10.1089/thy.1996.6.409 · Cited by 98
Zuo, H., Gandhi, M., Edreira, M. M., Hochbaum, D. R., Nimgaonkar, V. L., Zhang, P., DiPaola, J. E., Evdokimova, V. N., Altschuler, D. L., & Nikiforov, Y. E. (2010) · Cancer Research · doi:10.1158/0008-5472.can-09-2812 · Cited by 96
Pizzolanti, G., Russo, L., Richiusa, P., Bronte, V., Nuara, R. B., Rodolico, V., Amato, M. C., Smeraldi, L., Sisto, P. S., Nucera, M., et al. (2007) · Thyroid · doi:10.1089/thy.2007.0008 · Cited by 95
Fagin, J. A., Tang, S., Zeki, K., Lauro, R. D., Fusco, A., & Gonsky, R. (1996) · PubMed · Cited by 93
Undifferentiated and poorly differentiated carcinoma.
Rosaí, J., Saxén, E., & Woolner, L. B. (1985) · PubMed · Cited by 92
Genetic Alterations in Thyroid Tumor Progression: Association with p53 Gene Mutations
Ito, T., Seyama, T., Mizuno, T., Tsuyama, N., Hayashi, Y., Dohi, K., Nakamura, N., & Akiyama, M. (1993) · Japanese Journal of Cancer Research · doi:10.1111/j.1349-7006.1993.tb00171.x · Cited by 91
Expression of human telomerase subunits in ovarian malignant, borderline and benign tumors
Kyo, S., Kanaya, T., Takakura, M., Tanaka, M., Yamashita, A., Inoue, H., & Inoue, M. (1999) · International Journal of Cancer · doi:10.1002/(sici)1097-0215(19990315)80:6 · Cited by 90
Khoo, M. L. C., Ezzat, S., Freeman, J. L., & Asa, S. L. (2002) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.87.4.8352 · Cited by 90
Hunt, J. L., Tometsko, M., LiVolsi, V. A., Swalsky, P. A., Finkelstein, S. D., & Barnes, E. L. (2003) · The American Journal of Surgical Pathology · doi:10.1097/00000478-200312000-00009 · Cited by 89
Jażdżewski, K., Bogusławska, J., Jendrzejewski, J., Liyanarachchi, S., Pachucki, J., Wardyn, K. A., Nauman, A., & de la Chapelle, A. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2010-1594 · Cited by 88
Hou, P., Liu, D., & Xing, M. (2007) · Cell Cycle · doi:10.4161/cc.6.3.3818 · Cited by 87
Molecular pathogenesis of thyroid cancer
Segev, D. L., Umbricht, C. B., & Zeiger, M. A. (2003) · Surgical Oncology · doi:10.1016/s0960-7404(03)00037-9 · Cited by 87
RET/PCM-1: a novel fusion gene in papillary thyroid carcinoma
Corvi, R., Berger, N., Balczon, R., & Romeo, G. (2000) · Oncogene · doi:10.1038/sj.onc.1203772 · Cited by 86
Epigenetics of thyroid cancer and novel therapeutic targets
Russo, D., Damante, G., Puxeddu, E., Durante, C., & Filetti, S. (2011) · Journal of Molecular Endocrinology · doi:10.1530/jme-10-0150 · Cited by 83
Nam, S. Y., Han, B., Ko, E. Y., Kang, S. S., Hahn, S. Y., Hwang, J., Nam, M. Y., Kim, J., Chung, J. H., Oh, Y. L., et al. (2010) · Thyroid · doi:10.1089/thy.2009.0226 · Cited by 82
Saiz, A. D., Olvera, M., Rezk, S. A., Florentine, B., McCourty, A., & Brynes, R. K. (2002) · The Journal of Pathology · doi:10.1002/path.1185 · Cited by 81
Carta, C., Moretti, S., Passeri, L., Barbi, F., Avenia, N., Cavaliere, A., Monacelli, M., Macchiarulo, A., Santeusanio, F., Tartaglia, M., et al. (2005) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2005.02401.x · Cited by 79
Is the BRAFV600E mutation useful as a predictor of preoperative risk in papillary thyroid cancer?
Nam, J. K., Jung, C. K., Song, B. J., Lim, D. J., Chae, B. J., Lee, N. S., Park, W. C., Kim, J. S., Jung, S. S., & Bae, J. S. (2011) · The American Journal of Surgery · doi:10.1016/j.amjsurg.2011.02.013 · Cited by 79
Molecular Pathobiology of Thyroid Neoplasms
Tallini, G. (2002) · Endocrine Pathology · doi:10.1385/ep:13:4:271 · Cited by 79
Salassidis, K., Bruch, J., Zitzelsberger, H. F., Lengfelder, E., Kellerer, A. M., & Bauchinger, M. (2000) · PubMed · Cited by 78
A Novel Complex BRAF Mutation Detected in a Solid Variant of Papillary Thyroid Carcinoma
Chiosea, S. I., Nikiforova, M. N., Zuo, H., Ogilvie, J. B., Gandhi, M., Seethala, R. R., Ohori, N. P., & Nikiforov, Y. E. (2009) · Endocrine Pathology · doi:10.1007/s12022-009-9073-3 · Cited by 76
HOOK3-RET : a novel type of RET/PTC rearrangement in papillary thyroid carcinoma
Ciampi, R., Giordano, T. J., Wikenheiser‐Brokamp, K. A., Koenig, R. J., & Nikiforov, Y. E. (2007) · Endocrine Related Cancer · doi:10.1677/erc-07-0039 · Cited by 76
Ying, H., Suzuki, H., Zhao, L., Willingham, M. C., Meltzer, P. S., & Cheng, S.-Y. (2003) · PubMed · Cited by 76
Involvement of RET oncogene in human tumours: specificity of RET activation to thyroid tumours
Santoro, M., Sabino, N., Ishizaka, Y., Ushijima, T., Carlomagno, F., Cerrato, A., Grieco, M., Battaglia, C., Martelli, M., Paulin, C., et al. (1993) · British Journal of Cancer · doi:10.1038/bjc.1993.370 · Cited by 75
BRAF mutation detection in indeterminate thyroid cytology specimens
Ohori, N. P., Singhal, R., Nikiforova, M. N., Yip, L., Schoedel, K. E., Coyne, C., McCoy, K. L., LeBeau, S. O., Hodak, S. P., Carty, S. E., et al. (2012) · Cancer Cytopathology · doi:10.1002/cncy.21229 · Cited by 74
The two genes generating RET/PTC3 are localized in chromosomal band 10q11.2
Minoletti, F., Butti, M. G., Coronelli, S., Miozzo, M. R., Sozzi, G., Pilotti, S., Tunnacliffe, A., Pierotti, M. A., & Bongarzone, I. (1994) · Genes Chromosomes and Cancer · doi:10.1002/gcc.2870110108 · Cited by 70
Jo, Y. S., Huang, S., Kim, Y., Lee, I. J., Kim, S. S., Kim, J., Oh, T., Moon, Y., An, S., Ro, H.-K., et al. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2008.03293.x · Cited by 69
Klugbauer, S., Lengfelder, E., Demidchik, E. P., & Hm, R. (1996) · PubMed · Cited by 68
Mutations of p53 in Thyroid Carcinoma with an Insular Component
Takeuchi, Y., Daa, T., Kashima, K., Yokoyama, S., Nakayama, I., & Noguchi, S. (1999) · Thyroid · doi:10.1089/thy.1999.9.377 · Cited by 68
Rochefort, P., Caillou, B., Michiels, F.-M., Ledent, C. A., Talbot, M., Schlumberger, M. J., Lavelle, F., Monier, R., & Feunteun, J. (1996) · PubMed · Cited by 66
Cited by
Sorted by citations
Prognostic biomarkers in thyroid cancer
Soares, P., Celestino, R., Melo, M., Fonseca, E., & Sobrinho-Simões, M. A. (2014) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-013-1521-2 · Cited by 54
Chen, H., Luo, D., Zhang, L., Lin, X., Luo, Q., Yi, H., Wang, J., Yan, X., Li, B., Chen, Y., et al. (2017) · Oncotarget · doi:10.18632/oncotarget.17398 · Cited by 29
Multikinase inhibitors use in differentiated thyroid carcinoma
Habra, M. A., Jasim, S., & Ozsari, L. (2014) · Biologics · doi:10.2147/btt.s57619 · Cited by 28
Revilla, G., Corcoy, R., Moral, A., Escolá‐Gil, J. C., & Mato, E. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20102466 · Cited by 20
Role of hemithyroidectomy in differentiated thyroid cancer
Gibelli, B., Dionisio, R., & Ansarin, M. (2015) · Current Opinion in Otolaryngology & Head & Neck Surgery · doi:10.1097/moo.0000000000000142 · Cited by 13
Metadata
- Authors
- Patel, K. N.
- Affiliations
- NYU Langone Health (US)
- Corresponding author
- Patel, Kepal N.
- ORCID
- Patel, Kepal N.
- Venue
- Oral Oncology
- Publisher
- Elsevier BV
- Published
- 2013-07
- Volume
- 49
- Issue
- 7
- Pages
- 711-721
- ISSN
- 1368-8375 (ISSN-L)
- OpenAlex
- W2072682157
- Cited by
- 6
- References
- 247
- Citations by year
- 2019: 1 · 2017: 1 · 2015: 1 · 2014: 3
- FWCI
- 0.20
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Oral Oncology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Cancer Diagnosis and Treatment
- Health Sciences › Medicine › Surgery › Thyroid and Parathyroid Surgery
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Thyroid Disorders and Treatments
- Keywords
- thyroid cancer, genetic mutations, molecular markers, carcinogenesis, prognostic factors, therapeutic target
- MeSH terms
- Cell Differentiation, Humans, Mutation, Thyroid Neoplasms, Biomarkers, Tumor
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review