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Development of a PROMIS item bank to measure pain interference
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This paper describes the psychometric properties of the PROMIS-pain interference (PROMIS-PI) bank. An initial candidate item pool (n=644) was developed and evaluated based on the review of existing instruments, interviews with patients, and consultation with pain experts. From this pool, a candidate item bank of 56 items was selected and responses to the items were collected from large community and clinical samples. A total of 14,848 participants responded to all or a subset of candidate items. The responses were calibrated using an item response theory (IRT) model. A final 41-item bank was evaluated with respect to IRT assumptions, model fit, differential item function (DIF), precision, and construct and concurrent validity. Items of the revised bank had good fit to the IRT model (CFI and NNFI/TLI ranged from 0.974 to 0.997), and the data were strongly unidimensional (e.g., ratio of first and second eigenvalue=35). Nine items exhibited statistically significant DIF. However, adjusting for DIF had little practical impact on score estimates and the items were retained without modifying scoring. Scores provided substantial information across levels of pain; for scores in the T-score range 50-80, the reliability was equivalent to 0.96-0.99. Patterns of correlations with other health outcomes supported the construct validity of the item bank. The scores discriminated among persons with different numbers of chronic conditions, disabling conditions, levels of self-reported health, and pain intensity (p<0.0001). The results indicated that the PROMIS-PI items constitute a psychometrically sound bank. Computerized adaptive testing and short forms are available.
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“PROMIS-Pain Interference measures the extent to which pain interferes with a patient’s physical, mental, emotional, and social activities in the past seven days and is highly reliable.23”
From Mindfulness is associated with psychological health and moderates the impact of fibromyalgia (2019) · cites this paper as [23]
Experimental — accuracy not yet measuredIn the citing paper
“Extensive effort has been made to validate the PROMIS measures,5, 7, 21, 51, 55, 72, 89, 92, 95 but there is modest information on their performance specifically in the context of cLBP.”
From Report of the NIH Task Force on research standards for chronic low back pain. (2014) · cites this paper as [5]
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Metadata
- Authors
- Amtmann, D., Cook, K. F., Jensen, M. P., Chen, W.-H., Choi, S., Revicki, D., Cella, D., Rothrock, N., Keefe, F., Callahan, L., & Lai, J.-S.
- Affiliations
- Northwestern University (US)
- University of Washington (US)
- United BioSource Corporation (United Kingdom) (GB)
- Duke University (US)
- University of North Carolina at Chapel Hill (US)
- Corresponding author
- Amtmann, Dagmar
- ORCID
- Venue
- Pain
- Published
- 2010-07
- Volume
- 150
- Issue
- 1
- Pages
- 173-182
- ISSN
- 0304-3959 (ISSN-L)
- PMC
- PMC2916053
- OpenAlex
- W1985564128
- Cited by
- 1,199
- References
- 61
- Citations by year
- 2026: 117 · 2025: 128 · 2024: 135 · 2023: 120 · 2022: 114 · 2021: 112 · 2020: 90 · 2019: 81 · 2018: 69 · 2017: 51 · 2016: 59 · 2015: 49 · 2014: 33 · 2013: 23 · 2012: 10
- FWCI
- 17.38
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Pain (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- Northwestern University (U01AR52177)
- University of Washington (U01AR52170, U01AR52155, U01AR52171, U01AR52158)
- University of Pittsburgh (U01AR52155, U01AR52158, U01AR52170, U01AR52171)
- Stony Brook University (U01AR52170)
- National Institutes of Health
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (U01AR052171, U01AR52186, U01 AR 52177, U01AR52181, U01AR52155, U01AR052186, U01AR52171, U01AR052170, U01AR052158, U01AR52170, U01AR052155, U01AR052177, U01AR52158, U01AR052181)
- Topics
- Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
- Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
- Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
- Keywords
- PROMIS, pain interference, item bank, patient-reported outcomes, item response theory, differential item functioning, construct validity, concurrent validity, chronic pain, computerized adaptive testing, short form
- MeSH terms
- Activities of Daily Living, Disability Evaluation, Female, Health Status, Humans, Male, Pain, Psychometrics, Quality of Life
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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