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Cited by 1,060Pain Mechanisms and TreatmentsPain Management and TreatmentMusculoskeletal pain and rehabilitation

The DOI matches its Crossref record; 101 of the 104 references it cites were found in a registry or an index.

NeuPSIG guidelines on neuropathic pain assessment

Haanpää, Maija, Attal, Nadine, Backonja, Miroslav, Baron, Ralf, Bennett, Michael, Bouhassira, Didier, Cruccu, Giorgio, Hansson, Per, Haythornthwaite, Jennifer A., Iannetti, Gian Domenico, Jensen, Troels S., Kauppila, Timo, Nurmikko, Turo J., Rice, Andew S.C., Rowbotham, Michael, Serra, Jordi, Sommer, Claudia, Smith, Blair H., Treede, Rolf-Detlef·2011·Pain
DOI 10.1016/j.pain.2010.07.031
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Abstract

This is a revision of guidelines, originally published in 2004, for the assessment of patients with neuropathic pain. Neuropathic pain is defined as pain arising as a direct consequence of a lesion or disease affecting the somatosensory system either at peripheral or central level. Screening questionnaires are suitable for identifying potential patients with neuropathic pain, but further validation of them is needed for epidemiological purposes. Clinical examination, including accurate sensory examination, is the basis of neuropathic pain diagnosis. For more accurate sensory profiling, quantitative sensory testing is recommended for selected cases in clinic, including the diagnosis of small fiber neuropathies and for research purposes. Measurement of trigeminal reflexes mediated by A-beta fibers can be used to differentiate symptomatic trigeminal neuralgia from classical trigeminal neuralgia. Measurement of laser-evoked potentials is useful for assessing function of the A-delta fiber pathways in patients with neuropathic pain. Functional brain imaging is not currently useful for individual patients in clinical practice, but is an interesting research tool. Skin biopsy to measure the intraepidermal nerve fiber density should be performed in patients with clinical signs of small fiber dysfunction. The intensity of pain and treatment effect (both in clinic and trials) should be assessed with numerical rating scale or visual analog scale. For future neuropathic pain trials, pain…

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  1. Rice, 1994, Microneurography and the investigation of pain mechanisms., Pain Reviews, 1, 123

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Metadata

Authors
Haanpää, M., Attal, N., Backonja, M., Baron, R., Bennett, M., Bouhassira, D., Cruccu, G., Hansson, P., Haythornthwaite, J. A., Iannetti, G. D., Jensen, T. S., Kauppila, T., Nurmikko, T. J., Rice, A. S. C., Rowbotham, M., Serra, J., Sommer, C., Smith, B. H., & Treede, R.-D.
Affiliations
  • University of Wisconsin–Madison (US)
  • Inserm (FR)
  • University Hospital Schleswig-Holstein (DE)
  • Sapienza University of Rome (IT)
  • Karolinska University Hospital (SE)
  • Johns Hopkins University (US)
  • University College London (GB)
  • Aarhus University Hospital (DK)
  • University of Helsinki (FI)
  • University of Liverpool (GB)
  • University of California, San Francisco (US)
  • Parc Científic de Barcelona (ES)
  • University of Würzburg (DE)
  • University of Aberdeen (GB)
  • Heidelberg University (DE)
Corresponding author
Haanpää, Maija
ORCID
Venue
Pain
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2011-01
Volume
152
Issue
1
Pages
14-27
ISSN
0304-3959 (ISSN-L)
DOI
10.1016/j.pain.2010.07.031
OpenAlex
W2026423509
Cited by
1,060
References
104
Citations by year
2026: 30 · 2025: 37 · 2024: 39 · 2023: 53 · 2022: 67 · 2021: 80 · 2020: 74 · 2019: 81 · 2018: 65 · 2017: 78 · 2016: 97 · 2015: 84 · 2014: 92 · 2013: 76 · 2012: 62
FWCI
5.88
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Pain (publishedVersion)
  • PubMed (publishedVersion)
  • Discovery Research Portal (University of Dundee) (submittedVersion)
  • UCL Discovery (University College London) (submittedVersion)
  • IRIS Research product catalog (Sapienza University of Rome) (submittedVersion)
Funders
  • NeuPSIG
  • Special Interest Group on Neuropathic Pain of the International Association for the Study of Pain (IASP®)
Topics
  • Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Treatment
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
Keywords
neuropathic pain, pain assessment, screening questionnaire, sensory examination, quantitative sensory testing, small fiber neuropathy, trigeminal neuralgia, laser-evoked potentials, functional neuroimaging, skin biopsy, intraepidermal nerve fiber density, pain intensity assessment, quality of life, sleep and mood
MeSH terms
Autonomic Nervous System, Diagnostic Imaging, Disability Evaluation, Evoked Potentials, Humans, Mass Screening, Neuralgia, Pain Measurement, Psychological Tests, Psychophysiologic Disorders, Quality of Life, Surveys and Questionnaires, Time Factors, Databases, Factual, Guidelines as Topic

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