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Early and Late Infections in Newborns: Where Do We Stand? A Review

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Cortese, Francesca, Scicchitano, Pietro, Gesualdo, Michele, Filaninno, Antonella, De Giorgi, Elsa, Schettini, Federico, Laforgia, Nicola, Ciccone, Marco Matteo·2016·Pediatrics & Neonatology

Abstract

Neonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish “early onset sepsis” when microbiological cultures positive for external pathogens come from newborns during the first 7 days of life (maternal intrapartum transmission); “late onset sepsis” when microbiological cultures positive for external pathogens come from newborns after the first 7 days from delivery (postnatal acquisition). In this review we synthesize the incidence, risk factors, clinical manifestations, and methods of diagnosis and treatment of each type of neonatal infection, in order to better define such a pathological condition which is of great importance in common clinical practice. Neonatal sepsis still represents an important cause of mortality and morbidity among infants. According to the onset, we can distinguish “early onset sepsis” when microbiological cultures positive for external pathogens come from newborns during the first 7 days of life (maternal intrapartum transmission); “late onset sepsis” when microbiological cultures positive for external pathogens come from newborns after the first 7 days from delivery (postnatal acquisition). In this review we synthesize the incidence, risk factors, clinical manifestations, and methods of diagnosis and treatment of each type of neonatal infection, in order to better define such a pathological condition which is of great importance in common clinical practice.

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Metadata

Authors
Cortese, F., Scicchitano, P., Gesualdo, M., Filaninno, A., De Giorgi, E., Schettini, F., Laforgia, N., & Ciccone, M. M.
Venue
Pediatrics & Neonatology
Publisher
Elsevier BV
Published
2016-08
Volume
57
Issue
4
Pages
265-273
ISSN
1875-9572 (ISSN-L)
OpenAlex
W2233730934
Cited by
283
References
43
FWCI
15.85
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Early and Late Infections in Newborns: Where Do We Stand? A Review. https://app.cochat.ai/papers/10.1016/j.pedneo.2015.09.007
The paper
Cortese, F., Scicchitano, P., Gesualdo, M., Filaninno, A., De Giorgi, E., Schettini, F., Laforgia, N., & Ciccone, M. M. (2016). Early and Late Infections in Newborns: Where Do We Stand? A Review. Pediatrics & Neonatology. https://doi.org/10.1016/j.pedneo.2015.09.007

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