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Cited by 365

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Sulfoxaflor and the sulfoximine insecticides: Chemistry, mode of action and basis for efficacy on resistant insects

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Sparks, Thomas C., Watson, Gerald B., Loso, Michael R., Geng, Chaoxian, Babcock, Jon M., Thomas, James D.·2013·Pesticide Biochemistry and Physiology

Abstract

The sulfoximines, as exemplified by sulfoxaflor ([N-[methyloxido[1-[6-(trifluoromethyl)-3-pyridinyl]ethyl]-λ(4)-sulfanylidene] cyanamide] represent a new class of insecticides. Sulfoxaflor exhibits a high degree of efficacy against a wide range of sap-feeding insects, including those resistant to neonicotinoids and other insecticides. Sulfoxaflor is an agonist at insect nicotinic acetylcholine receptors (nAChRs) and functions in a manner distinct from other insecticides acting at nAChRs. The sulfoximines also exhibit structure activity relationships (SAR) that are different from other nAChR agonists such as the neonicotinoids. This review summarizes the sulfoximine SAR, mode of action and the biochemistry underlying the observed efficacy on resistant insect pests, with a particular focus on sulfoxaflor.

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Metadata

Authors
Sparks, T. C., Watson, G. B., Loso, M. R., Geng, C., Babcock, J. M., & Thomas, J. D.
Venue
Pesticide Biochemistry and Physiology
Publisher
Elsevier BV
Published
2013-09
Volume
107
Issue
1
Pages
1-7
ISSN
0048-3575 (ISSN-L)
OpenAlex
W2093672492
Cited by
365
References
1
FWCI
7.40
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Sulfoxaflor and the sulfoximine insecticides: Chemistry, mode of action and basis for efficacy on resistant insects. https://app.cochat.ai/papers/10.1016/j.pestbp.2013.05.014
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Sparks, T. C., Watson, G. B., Loso, M. R., Geng, C., Babcock, J. M., & Thomas, J. D. (2013). Sulfoxaflor and the sulfoximine insecticides: Chemistry, mode of action and basis for efficacy on resistant insects. Pesticide Biochemistry and Physiology. https://doi.org/10.1016/j.pestbp.2013.05.014

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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