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Sp1 transcription factor: A long-standing target in cancer chemotherapy
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Category IV showed enrichment of TFBSs for core transcription factors, such as Sp1.
“In contrast, Category IV showed enrichment of TFBSs for core transcription factors, such as Sp1 which has essential roles in cell growth, differentiation, apoptosis, and carcinogenesis (Fig. 2C, iv) [27].”
From A cis-regulatory-directed pipeline for the identification of genes involved in cardiac development and disease (2021) · cites this paper as [27]
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Hallmarks of Cancer: The Next Generation
Hanahan, D., & Weinberg, R. A. (2011) · Cell · doi:10.1016/j.cell.2011.02.013 · Cited by 66,590
Nair, V., Sreevalsan, S., Basha, R., Abdelrahim, M., Abudayyeh, A., Rodrigues Hoffman, A., & Safe, S. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.592576 · Cited by 129
Pathi, S., Jutooru, I., Chadalapaka, G., Nair, V., Lee, S.-O., & Safe, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048208 · Cited by 127
Effects of anticancer drugs on transcription factor–DNA interactions
Gniazdowski, M., Denny, W. A., Nelson, S. M., & Czyz, M. (2005) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.9.3.471 · Cited by 41
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Lago, S., Nadai, M., Cernilogar, F. M., Kazerani, M., Domíniguez Moreno, H., Schotta, G., & Richter, S. N. (2021) · Nature Communications · doi:10.1038/s41467-021-24198-2 · Cited by 269
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Metadata
- Authors
- Vizcaíno, C., Mansilla, S., & Portugal, J.
- Venue
- Pharmacology & Therapeutics
- Publisher
- Elsevier BV
- Published
- 2015-08
- Volume
- 152
- Pages
- 111-124
- ISSN
- 0163-7258
- Cited by
- 377
- References
- 4
- Language
- en
- Funders
- European Social Fund
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