Drug repurposing in cancer

Cited by (333)

Items 101–200 of 333

1. Anti-invasive effects of minoxidil on human breast cancer cells: combination with ranolazine
   Shiwen Qiu, Scott P. Fraser, Wayne Pires, Mustafa B.A. Djamgoz · 2022 · Clinical & Experimental Metastasis
2. The Impact of Resolution of Inflammation on Tumor Microenvironment: Exploring New Ways to Control Cancer Progression
   Federica Liotti, Maria Marotta, Rosa Marina Melillo, Nella Prevete · 2022 · Cancers
3. Patient-Derived Xenograft vs. Organoids: A Preliminary Analysis of Cancer Research Output, Funding and Human Health Impact in 2014–2019
   Lindsay J. Marshall, Marcia Triunfol, Troy Seidle · 2020 · Animals
4. A comprehensive review of discovery and development of drugs discovered from 2020–2022
   Usman Shareef, Aisha Altaf, Madiha Ahmed, Nosheen Akhtar, Mohammed Saad Almuhayawi, Soad Khalil Al Jaouni, Samy Selim, Mohamed Abdelwahab Abdelgawad, Mohammed Kamal Nagshabandi · 2023 · Saudi Pharmaceutical Journal
5. High-throughput screening as a drug repurposing strategy for poor outcome subgroups of pediatric B-cell precursor Acute Lymphoblastic Leukemia
   Athanasios Oikonomou, Luigia Valsecchi, Manuel Quadri, Titus Watrin, Katerina Scharov, Simona Procopio, Jia‐Wey Tu, Melina Vogt, Angela Maria Savino, Daniela Silvestri et al. · 2023 · Biochemical Pharmacology
6. The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: A study based on TCGA and Cmap datasets
   Jinshu Pang, Zhe‐Kun Li, Peng Lin, Xiao‑Dong Wang, Gang Chen, Hai-biao Yan, Shenghua Li · 2019 · Oncology Reports
7. Lomerizine 2HCl inhibits cell proliferation and induces protective autophagy in colorectal cancer via the PI3K/Akt/mTOR signaling pathway
   Xiangpeng Tan, Yan He, Yun‐Na Huang, Can‐Can Zheng, Junqi Li, Qin‐Wen Liu, Ming‐Liang He, Bin Li, Wenwen Xu · 2021 · MedComm
8. Nitroxoline: repurposing its antimicrobial to antitumor application
   Janko Kos, Ana Mitrović · 2019 · Acta Biochimica Polonica
9. Repurposed Analog of GLP-1 Ameliorates Hyperglycemia in Type 1 Diabetic Mice Through Pancreatic Cell Reprogramming
   Adrian Villalba, Silvia Rodríguez-Fernández, David Perna‐Barrull, Rosa-Maria Ampudia, Laia Gómez-Muñoz, Irma Pujol‐Autonell, Eva Aguilera, Mireia Coma, Mary Cano‐Sarabia, Federico Vázquez et al. · 2020 · Frontiers in Endocrinology
10. Drug Repositioning of the α1-Adrenergic Receptor Antagonist Naftopidil: A Potential New Anti-Cancer Drug?
    Romane Florent, Laurent Poulain, Monique N’Diaye · 2020 · International Journal of Molecular Sciences
11. The effect of itraconazole on the clinical outcomes of patients with advanced non-small cell lung cancer receiving platinum-based chemotherapy: a randomized controlled study
    Mohamed, Asmaa Waheed, Elbassiouny, Mohamed, Elkhodary, Dalia Abdelghany, Shawki, May Ahmed, Saad, Amr Shafik · 2021 · Medical Oncology
12. Dual contribution of the mTOR pathway and of the metabolism of amino acids in prostate cancer
    Alejandro Schcolnik‐Cabrera, Daniel Juárez-López · 2022 · Cellular Oncology
13. Inclusion of Nitrofurantoin into the Realm of Cancer Chemotherapy via Biology-Oriented Synthesis and Drug Repurposing
    Perihan A. Elzahhar, Hisham A. Nematalla, Houssam Al-Koussa, Carla Abrahamian, Amira Fawzy El-Yazbi, Larry Bodgi, Jolie Bou-Gharios, Joyce Azzi, Joëlle Al-Choboq, Hala F. Labib et al. · 2023 · Journal of Medicinal Chemistry
14. Repurposing drugs in autophagy for the treatment of cancer: From bench to bedside
    Faqian Bu, Jifa Zhang, Shuai Wen, Jie Liu, Qiu Sun, Liang Ouyang · 2021 · Drug Discovery Today
15. A computational multi-targeting approach for drug repositioning for psoriasis treatment
    Akachukwu Ibezim, Emmanuel Onah, Ebubechukwu Nnamdi Dim, Fidele Ntie‐Kang · 2021 · BMC Complementary Medicine and Therapies
16. WaterMap and Molecular Dynamic Simulation-Guided Discovery of Potential PAK1 Inhibitors Using Repurposing Approaches
    Jayashree Biswal, Prajisha Jayaprakash, Suresh Kumar Rayala, Ganesh Venkatraman, Raghu Rangaswamy, Jeyaraman Jeyakanthan · 2021 · ACS Omega
17. Unlocking the Untapped Potential of Endothelial Kinase and Phosphatase Involvement in Sepsis for Drug Treatment Design
    Matthijs Luxen, Matijs van Meurs, Grietje Molema · 2022 · Frontiers in Immunology
18. Targeting GRP75 with a Chlorpromazine Derivative Inhibits Endometrial Cancer Progression Through GRP75–IP3R‐Ca 2+ ‐AMPK Axis
    Qi Wang, Lijuan Li, Xiaoyan Gao, Chunxue Zhang, Xu Chen, Lingyi Song, Jian Li, Xiao Guang Sun, Fei Mao, Yudong Wang · 2024 · Advanced Science
19. Identification of a Five-Gene Prognostic Model and Its Potential Drug Repurposing in Colorectal Cancer Based on TCGA, GTEx and GEO Databases
    Feng Yang, Shaoyi Cai, Li Ling, Haiji Zhang, Liang Tao, Qin Wang · 2021 · Frontiers in Genetics
20. Drug Repurposing in Oncology: Current Evidence and Future Direction
    Zhenzhan Zhang, Jianguang Ji, Hao Liu · 2020 · Current Medicinal Chemistry
21. Anti-proliferative activity of disulfiram through regulation of the AKT-FOXO axis: A proteomic study of molecular targets
    Nasrollahzadeh, Ali, Momeny, Majid, Fasehee, Hamidreza, Yaghmaie, Marjan, Bashash, Davood, Hassani, Saeed, Mousavi, Seyed A., Ghaffari, Seyed H. · 2021 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
22. Oxethazaine inhibits esophageal squamous cell carcinoma proliferation and metastasis by targeting aurora kinase A
    Zhuo Bao, Ang Li, Xuebo Lu, Zitong Wang, Yu Yin, Wenjie Wu, Lili Zhao, Bo Li, Xiangyu Wu, Kyle Vaughn Laster et al. · 2022 · Cell Death and Disease
23. Drug-based therapy for advanced adenoid cystic carcinoma: Current landscape and challenges based on an overview of registered clinical trials
    Vivian Petersen Wagner, Renata Ferrarotto, Pablo Agustín Vargas, Manoela Domingues Martins, Colin D. Bingle, Lynne Bingle · 2022 · Critical Reviews in Oncology/Hematology
24. Repurposing Drugs for Acute Myeloid Leukemia: A Worthy Cause or a Futile Pursuit?
    Anna V. Wojcicki, Meena Kadapakkam, Adam R. Frymoyer, Norman James Lacayo, Hee-Don Chae, Kathleen M. Sakamoto · 2020 · Cancers
25. Sertaconazole provokes proapoptotic autophagy via stabilizing TRADD in nonsmall cell lung cancer cells
    Wenhui Zhang, Li Zhou, Siyuan Qin, Jingwen Jiang, Zhao Huang, Zhe Zhang, Xiyu Zhang, Zheng Shi, Jie Lin · 2021 · MedComm
26. Drug Repurposing to Identify a Synergistic High-Order Drug Combination to Treat Sunitinib-Resistant Renal Cell Carcinoma
    Magdalena Rausch, Adriano Rutz, Pierre‐Marie Allard, Céline Delucinge-Vivier, Mylène Docquier, Olivier Dormond, Paul J. Dyson, Jean‐Luc Wolfender, Patrycja M. Nowak-Sliwinska · 2021 · Cancers
27. Repurposing Amphotericin B: anti-microbial, molecular docking and molecular dynamics simulation studies suggest inhibition potential of Amphotericin B against MRSA
    Neha Farid, Khair Bux, Kashif Ali, Asma Bashir, Rahima Tahir · 2023 · BMC Chemistry
28. Microfluidic organoid-slice-on-a-chip system for studying anti-cholangiocarcinoma drug efficacy and hepatorenal toxicity
    Jie Liu, Guohua Wu, Di Wu, Lin Wu, Chenwei Sun, Wenlong Zhang, Qijun Du, Qinrui Lu, Wenqi Hu, Hongyu Meng et al. · 2025 · Lab on a Chip
29. CRISPR-dCas9-Based Artificial Transcription Factors to Improve Efficacy of Cancer Treatment With Drug Repurposing: Proposal for Future Research
    Alejandro Martinez‐Escobar, Benjamín Luna-Callejas, Eva Ramón‐Gallegos · 2021 · Frontiers in Oncology
30. Screening of GPCR drugs for repurposing in breast cancer
    Noor Mazin Abdulkareem, Raksha R. Bhat, Reid Trenton Powell, Soumya G. Chikermane, S. Yande, Lisa Trinh, Hala Y. Abdelnasser, Mantasha Tabassum, Alexis Ruiz, Mary M. Sobieski et al. · 2022 · Frontiers in Pharmacology
31. Optimizing cancer therapy: a review of the multifaceted effects of metronomic chemotherapy
    Oyku Yagmur Basar, Sawsan G. A. A. Mohammed, M. Walid Qoronfleh, Ahmet Acar · 2024 · Frontiers in Cell and Developmental Biology
32. A drug repurposing study identifies novel FOXM1 inhibitors with in vitro activity against breast cancer cells
    Khaled A. N. Abusharkh, Ferah Cömert Önder, Venhar Çınar, Zühal Hamurcu, Bülent Özpolat, Mehmet Ay · 2024 · Medical Oncology
33. Unveiling anticancer potential of glibenclamide: Its synergistic cytotoxicity with doxorubicin on cancer cells
    Subramaniyam Nithyananthan, Suyavaran Arumugam, Elizabeth Babu, Subastri Ariraman, Indrani Biswas, Suresh Kumar Muthuvel, Aristatile Balakrishnan, Ghedeir Muslem Alshammari, Chinnasamy Thirunavukkarasu · 2018 · Journal of Pharmaceutical and Biomedical Analysis
34. Comprehensive molecular docking and dynamic simulations for drug repurposing of clinical drugs against multiple cancer kinase targets
    Nilofer Shaikh, R. K Linthoi, K. Venkateswara Swamy, Muthukumarasamy Karthikeyan, Renu Vyas · 2022 · Journal of Biomolecular Structure and Dynamics
35. Analogs of penfluridol as chemotherapeutic agents with reduced central nervous system activity
    Md Ashraf-Uz-Zaman, Md Sanaullah Sajib, Luca Cucullo, Constantinos Marios Mikelis, Nadezhda German · 2018 · Bioorganic & Medicinal Chemistry Letters
36. Repurposing of FDA-Approved NSAIDs for DPP-4 Inhibition as an Alternative for Diabetes Mellitus Treatment: Computational and in Vitro Study
    Veera Chandra Sekhar Reddy Chittepu, Poonam Kalhotra, Tzayhri Osorio-Gallardo, Tzayhrí Gallardo‐Velázquez, Guillermo Ismael Osorio-Revilla · 2019 · Pharmaceutics
37. Has Drug Repurposing Fulfilled Its Promise in Acute Myeloid Leukaemia?
    Debora Valli, Alicja Gruszka, Myriam Alcalay · 2020 · Journal of Clinical Medicine
38. Nano-synergistic combination of Erlotinib and Quinacrine for non-small cell lung cancer (NSCLC) therapeutics – Evaluation in biologically relevant in-vitro models
    Nishant S. Kulkarni, Bhuvaneshwar Vaidya, Vivek Gupta · 2021 · Materials Science and Engineering C
39. Doxycycline inhibits the progression of metastases in early-stage osteosarcoma by downregulating the expression of MMPs, VEGF and ezrin at primary sites
    Argyris Costas Hadjimichael, Athanasios F. Foukas, Εvangelia Papadimitriou, Angelos Kaspiris, Chrysostomi Peristiani, Ioannis Chaniotakis, Maria Kotsari, Alexandros Pergaris, Stamatios E Theocharis, Panagiotis Sarantis et al. · 2022 · Cancer Treatment and Research Communications
40. Novel Strategies for Cancer Combat: Drug Combination Using Repurposed Drugs Induces Synergistic Growth Inhibition of MCF-7 Breast and HT-29 Colon Cancer Cells
    Diana Duarte, Inês Guerreiro, Nuno Vale · 2022 · Current Issues in Molecular Biology
41. The Potential Role of Timosaponin-AIII in Cancer Prevention and Treatment
    Zhaowen Liu, Yifan Cao, Xiaohua Guo, Zhixi Chen · 2023 · Molecules
42. Cinnamic Acid: A Low-Toxicity Natural Bidentate Ligand for Uranium Decorporation
    Yawen Liu, Bin Zhao, Pan He, Zeru Wang, Kui Tang, Zhiwei Mou, Yi Tan, Linzhen Wu, Guangyuan Chen, Xiaoan Li et al. · 2024 · Inorganic Chemistry
43. Small Molecule Inhibitors Targeting Key Proteins in the DNA Damage Response for Cancer Therapy
    Lulu Li, Alagamuthu Karthick Kumar, Zhigang Hu, Zhigang Guo · 2020 · Current Medicinal Chemistry
44. The Effect of Beta-Adrenergic Blocking Agents in Cutaneous Melanoma—A Nation-Wide Swedish Population-Based Retrospective Register Study
    Dimitrios Katsarelias, Hanna Eriksson, Rasmus Mikiver, Isabelle Krakowski, Jonas A. Nilsson, Lars Ny, Roger Olofsson Bagge · 2020 · Cancers
45. Statins and Gliomas: A Systematic Review of the Preclinical Studies and Meta-Analysis of the Clinical Literature
    Luis Fernando Rendón, Ishaan Ashwini Tewarie, David J. Coté, Aaron Gabriel, Timothy Richard Smith, Marike L. D. Broekman, Rania A. Mekary · 2022 · Drugs
46. Repurposing Quinacrine for Treatment of Malignant Mesothelioma: In-Vitro Therapeutic and Mechanistic Evaluation
    Nishant S. Kulkarni, Bhuvaneshwar Vaidya, Vineela Parvathaneni, Debarati Bhanja, Vivek Gupta · 2020 · International Journal of Molecular Sciences
47. Inhibition of Radiation and Temozolomide-Induced Glioblastoma Invadopodia Activity Using Ion Channel Drugs
    Marija Dinevska, Natalia Gazibegovic, Andrew P. Morokoff, Andrew Henry Kaye, Katharine Jann Drummond, Theo Mantamadiotis, Stanley S. Stylli · 2020 · Cancers
48. Alcohol-abuse drug disulfiram targets pediatric glioma via MLL degradation
    Meier, Stefanie, Cantilena, Sandra, Niklison Chirou, Maria Victoria, Anderson, John, Hargrave, Darren, Salomoni, Paolo, de Boer, Jasper, Michod, David · 2021 · Cell Death & Disease
49. Identification of a druggable pocket of the calcium-activated chloride channel TMEM16A in its open state
    Sai Shi, Biao Ma, Qiushuang Ji, Shuai Guo, Hailong An, Sheng Ye · 2023 · Journal of Biological Chemistry
50. The Mitochondrial ATP Synthase/IF1 Axis in Cancer Progression: Targets for Therapeutic Intervention
    Sonia Domínguez-Zorita, Jose Manuel Cuezva · 2023 · Cancers
51. Feasibility of Repurposing Clioquinol for Cancer Therapy
    Raheel Khan, Harras J. Khan, Yassen Abdullah, Q. Ping Dou · 2020 · Recent Patents on Anti-Cancer Drug Discovery
52. A New Method for Ethical and Efficient Evidence Generation for Off-Label Medication Use in Oncology (A Case Study in Glioblastoma)
    Samir G. Agrawal, Padman Vamadevan, Ndaba Mazibuko, Robin Bannister, Raphael Swery, Shanna Wilson, Sarah Edwards · 2019 · Frontiers in Pharmacology · Retracted
53. Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach
    Leire Dublang, Jarl Underhaug, Marte I. Flydal, Lorea Velasco‐Carneros, Jean‐Didier Maréchal, Fernando Moro, María Dolores Boyano, Aurora Martı́nez, Arturo Muga · 2021 · Cancers
54. Niclosamide (NA) overcomes cisplatin resistance in human ovarian cancer
    Linjuan Huang, Jing Zhang, Youling Deng, Hao Wang, Piao Zhao, Guozhi Zhao, Wei Zeng, Yonghui Wang, Connie Chen, William Wagstaff et al. · 2023 · Genes & Diseases
55. The DrugPattern tool for drug set enrichment analysis and its prediction for beneficial effects of oxLDL on type 2 diabetes
    Chuanbo Huang, Weili Yang, Junpei Wang, Yuan Zhou, Bin Geng, Georgios Kararigas, Jichun Yang, Qinghua Cui · 2018 · Journal of genetics and genomics/Journal of Genetics and Genomics
56. Unveiling promising inhibitors of superoxide dismutase 1 (SOD1) for therapeutic interventions
    Akhtar Atiya, Abdullatif Bin Muhsinah, Mohammed Alrouji, Fahad Abdulrahman Alhumaydhi, Waleed Al Abdulmonem, Mohammad Abdullah Aljasir, Sharaf E. Sharaf, Mohammad Furkan, Rizwan Hasan Khan, Moyad Jamal Shahwan et al. · 2023 · International Journal of Biological Macromolecules
57. Metformin suppresses self‐renewal and stemness of cancer stem cell models derived from pluripotent stem cells
    Maram Hussein Zahra, Said M. Afify, Ghmkin Hassan, Hend M. Nawara, Kazuki Kumon, Akimasa Seno, Masaharu Seno · 2021 · Cell Biochemistry and Function
58. Drug repurposing for diabetes mellitus: In silico and in vitro investigation of DrugBank database for α-glucosidase inhibitors
    Morteza Sadeghi, Mehran Miroliaei, Mustafa Ghanadian · 2024 · International Journal of Biological Macromolecules
59. From Psychiatry to Oncology: Exploring the Anti‐Neoplastic Mechanisms of Aripiprazole and Its Potential Use in Cancer Treatment
    Liam A. O’Callaghan, C Blum, Katie Powell, Russ Chess‐Williams, Catherine McDermott · 2025 · Pharmacology Research & Perspectives
60. Simvastatin potentiates the cell-killing activity of imatinib in imatinib-resistant chronic myeloid leukemia cells mainly through PI3K/AKT pathway attenuation and Myc downregulation
    Lihong Ding, Qinwei Chen, Kai Chen, Yuelong Jiang, Genhong Li, Qiuling Chen, Dongyu Bai, Dehong Gao, Manman Deng, Haiping Zhang et al. · 2021 · European Journal of Pharmacology
61. Two Possible Strategies for Drug Modification of Gemcitabine and Future Contributions to Personalized Medicine
    Mariana Pereira, Nuno Vale · 2022 · Molecules
62. The antagonist of β-adrenergic receptor propranolol inhibits T cell lymphoma growth and enhances antitumor efficacy of cisplatin in vivo: A role of modulated apoptosis, glucose metabolism, pH regulation, and antitumor immune response
    Rajan Kumar Tiwari, Shiv Govind Rawat, Ajay Kumar V · 2023 · International Immunopharmacology
63. Metformin in overcoming enzalutamide resistance in castration-resistant prostate cancer
    Kendall Elizabeth Simpson, Derek B. Allison, Daheng He, Jinpeng Liu, Chi Wang, Xiaoqi Liu · 2024 · Journal of Pharmacology and Experimental Therapeutics
64. Repurposing FDA-approved drugs for COVID-19: targeting the main protease through multi-phase in silico approach
    Ahmed M. Metwaly, Eslam B. Elkaeed, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Hazem Elkady, Ibrahim H. Eissa · 2024 · Antiviral Therapy
65. H1 Antihistamines—Promising Candidates for Repurposing in the Context of the Development of New Therapeutic Approaches to Cancer Treatment
    Ewa Trybus, Wojciech Trybus · 2024 · Cancers
66. Challenges and Opportunities in Repurposing of Drugs: Mini Review
    Selvam Sindhu, S Murugan · 2020 · Bangladesh Journal of Medical Science
67. Quinazoline alpha-adrenoreceptor blockers as an adjunct cancer treatment: From bench to bedside.
    Liam D King, D. Christie, Wendy Dare, N. Bernaitis, R. Chess-Williams, C. McDermott, Amanda Forbes, S. Anoopkumar-Dukie · 2020 · European Journal of Pharmacology
68. Proteomics and Drug Repurposing in CLL towards Precision Medicine
    Dimitra Mavridou, Konstantina Psatha, Michalis Aivaliotis · 2021 · Cancers
69. An EZH2 blocker sensitizes histone mutated diffuse midline glioma to cholesterol metabolism inhibitors through an off-target effect
    Farah Rahal, Caroline Capdevielle, Benoit Rousseau, Julien Izotte, Jean‐William Dupuy, David Cappellen, Guillaume Chotard, Mélissa Ménard, Justine Charpentier, Vincent Jecko et al. · 2022 · Neuro-Oncology Advances
70. Atorvastatin inhibits the proliferation of MKN45-derived gastric cancer stem cells in a mevalonate pathway-independent manner
    Ye Seul Choi, Hee Jeong Cho, Hye Jin Jung · 2022 · Korean Journal of Physiology and Pharmacology
71. Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia
    Timothy Johanssen, Laura E. McVeigh, Sara Erridge, Geoff Stuart Higgins, Joelle P. Straehla, Margaret C. Frame, Tero A. Aittokallio, Neil O. Carragher, Daniel V. Ebner · 2023 · Frontiers in Oncology
72. Immunomodulatory, apoptotic and anti-proliferative potentials of sildenafil in Ehrlich ascites carcinoma murine model: In vivo and in silico insights
    Dalia S. Morsi, Ibrahim Omar Barnawi, Hany Mohammed Ibrahim, Asmaa M. El-Morsy, Mahmoud A. El Hassab, Heba Mohammed Abd El Latif · 2023 · International Immunopharmacology
73. Drug repurposing for Basal breast cancer subpopulations using modular network signatures
    Hiram Coria-Rodríguez, Soledad Ochoa, Guillermo de Anda‐Jáuregui, Enrique Hernandez Lemus · 2023 · Computational Biology and Chemistry
74. Poly-pharmacology of existing drugs: How to crack the code?
    Baptiste Mouysset, Marion Le Grand, Luc Camoin, Eddy Pasquier · 2024 · Cancer Letters
75. Repurposing Individualized Nutritional Intervention as a Therapeutic Component to Prevent the Adverse Effects of Radiotherapy in Patients With Cervical Cancer
    Ana Karen Medina-Jiménez, Rebeca Monroy‐Torres · 2020 · Frontiers in Oncology
76. New Peptide Functionalized Nanostructured Lipid Carriers with CNS Drugs and Evaluation Anti-proliferative Activity
    Sara Silva, Joana Marques Marto, Lídia Gonçalves, Diana Duarte, Olívia S.G.P. Soares, Francisco Vasques‐Nóvoa, António José Almeida, Nuno Vale · 2022 · International Journal of Molecular Sciences
77. Repurposing flubendazole for glioblastoma ferroptosis by affecting xCT and TFRC proteins
    Teng Wei, Yuanguo Ling, Niya Long, Wu Cen, Hongzhi Zhang, Lishi Jiang, Jian Liu, Xingwang Zhou, Liangzhao Chu · 2024 · Journal of Cellular and Molecular Medicine
78. Quality by design endorsed atorvastatin-loaded nanostructured lipid carriers embedded in pH-responsive gel for melanoma
    Deepkumar Bagasariya, Kondasingh Charankumar, Saurabh Shah, Paras Famta, Valencia Fernandes, Syed Shahrukh, Dharmendra Kumar Khatri, Shashi Bala Singh, Saurabh Srivastava · 2023 · Journal of Microencapsulation
79. Clinical and Immunological Outcomes in High-Risk Resected Melanoma Patients Receiving Peptide-Based Vaccination and Interferon Alpha, With or Without Dacarbazine Preconditioning: A Phase II Study
    Francesca Urbani, Virginia Ferraresi, Imerio Capone, Iole Macchia, Belinda Palermo, Carmen M. A. Nuzzo, Angela Torsello, Patrizio Pezzotti, Diana Giannarelli, Anna Fausta Pozzi et al. · 2020 · Frontiers in Oncology
80. Repositioning of Etravirine as a Potential CK1ε Inhibitor by Virtual Screening
    Luis Córdova-Bahena, Axel A. Sánchez-Álvarez, Angel Jonathan Ruiz-Moreno, Marco Antonio Velasco-Velázquez · 2021 · Pharmaceuticals
81. Formulation, characterization, cytotoxicity and Salmonella/microsome mutagenicity (Ames) studies of a novel 5-fluorouracil derivative
    Çinel Köksal Karayıldırım, Mustafa Kotmakçı, Erkan Halay, Kadir Ay, Yücel Başpınar · 2018 · Saudi Pharmaceutical Journal
82. Functional network analysis reveals potential repurposing of β-blocker atenolol for pancreatic cancer therapy
    Adam Hermawan, Herwandhani Putri, Rohmad Yudi Utomo · 2020 · DARU Journal of Pharmaceutical Sciences
83. Anti-cancer effects of nitazoxanide in epithelial ovarian cancer in-vitro and in-vivo
    Xiangqun Yang, Zhenyan Liu, Xin Wang, Wenda Tian, Taoyu Zhao, Qiaoling Yang, Wenliang Li, Linlin Yang, Hongying Yang, Yue Jia · 2024 · Chemico-Biological Interactions
84. Repurposing FDA-Approved Drugs as Potential Inhibitors of SARS-CoV-2 PLpro: A Comprehensive Computational Study
    Ahmed M. Metwaly, Eslam B. Elkaeed, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Omar Soliman, Hazem Elkady, Ibrahim H. Eissa · 2024 · Journal of Computational Biophysics and Chemistry
85. Discovery of potential FDA-approved SARS-CoV-2 Papain-like protease inhibitors: A multi-phase in silico approach
    Ahmed M. Metwaly, Eslam B. Elkaeed, Mohamed M. Khalifa, Aisha A. Alsfouk, Fatma G. Amin, Ibrahim M. Ibrahim, Ibrahim H. Eissa · 2024 · Journal of Chemical Research
86. Drug repurposing in oncology: a path beyond the bottleneck
    Neha Sajwani, Giridhara Prema Suchitha, Thottethodi Subrahmanya Keshava Prasad, Shobha Dagamajalu · 2025 · Medical Oncology
87. Drug repurposing in cancer research: a bibliometric analysis
    Uche Samuel Ndidi, Israel Ogwuche Ogra, Emohchonne Utos Jonathan, Okechukwu Kalu Iroha · 2025 · Discover Oncology
88. Raloxifene and bazedoxifene as selective ALDH1A1 inhibitors to ameliorate cyclophosphamide resistance: A drug repurposing approach
    Gera Narendra, Baddipadige Raju, Himanshu Verma, Manoj Kumar, Subheet Kumar Jain, Gurleen Kaur Tung, Shubham Thakur, Rasdeep Kour, Satwinderjeet Kaur, Bharti Sapra et al. · 2023 · International Journal of Biological Macromolecules
89. Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1‑related anti‑apoptotic proteins
    Paksiree Saranaruk, Ryusho Kariya, Gunya Sittithumcharee, Parichart Boueroy, Thidarut Boonmars, Kanlayanee Sawanyawisuth, Chaisiri Wongkham, Sopit Wongkham, Seiji Okada, Kulthida Vaeteewoottacharn · 2020 · International Journal of Molecular Medicine
90. Effective therapeutic strategies in a preclinical mouse model of Charcot–Marie–Tooth disease
    Cristina Nuevo‐Tapioles, Fulvio Santacatterina, Brenda Sánchez-Garrido, Cristina Núñez de Arenas, Adrián Robledo-Bérgamo, Paula Martínez-Valero, Lara Cantarero, Beatriz Pardo, Janet Hoenicka, Michael P. Murphy et al. · 2021 · Human Molecular Genetics
91. IUPHAR review – Data-driven computational drug repurposing approaches for opioid use disorder
    Zhenxiang Gao, Pingjian Ding, Rong Xu · 2023 · Pharmacological Research
92. The chorioallantoic membrane (CAM) model: From its origins in developmental biology to its role in cancer research
    María Jimena Mosna, Federico J Garde, Marcelo Gabriel Stinson, Candela D Pastore, Abel L. Carcagno · 2024 · Developmental Biology
93. Drug repurposing a compelling cancer strategy with bottomless opportunities
    Rasmita Dash, Madhulika Yadav, Jyotirmaya Biswal, Shrabani Samanta, Tripti Sharma, Sujata Mohapatra · 2023 · Indian Journal of Pharmacology
94. Synthesis of Novel Nitroxoline Analogs with Potent Cathepsin B Exopeptidase Inhibitory Activity
    Tim Van de Walle, Marina Briand, Ana Mitrović, Izidor Sosič, Stanislav Gobec, Janko Kos, Leentje Persoons, Dirk Daelemans, Steven De Jonghe, Zorica Ubiparip et al. · 2020 · ChemMedChem
95. Response Predictive Markers and Synergistic Agents for Drug Repositioning of Statins in Ovarian Cancer
    Yusuke Kobayashi, Takashi Takeda, Haruko Kunitomi, Fumiko Chiwaki, Masayuki Komatsu, Shimpei Nagai, Yuya Nogami, Kosuke Tsuji, Kenta Masuda, Hideaki Ogiwara et al. · 2022 · Pharmaceuticals
96. High-Throughput Drug Library Screening in Primary KMT2A-Rearranged Infant ALL Cells Favors the Identification of Drug Candidates That Activate P53 Signaling
    Priscilla Wander, Susan T.C.J.M. Arentsen-Peters, Kirsten S. Vrenken, Sandra S. Pinhanços, Bianca Koopmans, M. Emmy M. Dolman, Luke Jones, Patricia Garrido Castro, Pauline Schneider, Mark JB Kerstjens et al. · 2022 · Biomedicines
97. Atorvastatin and Nitrofurantoin Repurposed in the Context of Breast Cancer and Neuroblastoma Cells
    Catarina Costa Moura, Ana Salomé Correia, Mariana Pereira, Eduarda Ribeiro, Joana Santos, Nuno Vale · 2023 · Biomedicines
98. Repurposing of neprilysin inhibitor ‘sacubitrilat’ as an anti-cancer drug by modulating epigenetic and apoptotic regulators
    Navanath Kumbhar, Snehal Nimal, Deeksha Patil, V. Florian Kaiser, Joachim Haupt, Rajesh Nivarti Gacche · 2023 · Scientific Reports
99. Drug Repositioning for COVID-19
    Vicente Benavides-Córdoba · 2020 · Colombia medica
100. Effect of statin use on head and neck cancer prognosis in a multicenter study using a Common Data Model
     Soobeen Seol, Jung Ran Choi, Byungjin Choi, Sungryeal Kim, Ja Young Jeon, Ki Nam Park, Jae Hong Park, Min Woo Park, Young‐Gyu Eun, Jung Je Park et al. · 2023 · Scientific Reports