Lipid accumulation in non-adipose tissue and lipotoxicity

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Items 201–300 of 500

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3. Impact of Obesity-Related Inflammation on Cardiac Metabolism and Function
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4. The Dark Side of Sphingolipids: Searching for Potential Cardiovascular Biomarkers
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6. Poliphenolic-rich extracts from cocoa (Theobroma cacao L.) and cupuassu (Theobroma grandiflorum Willd. Ex Spreng. K. Shum) liquors: A comparison of metabolic effects in high-fat fed rats
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7. High-fat diets rich in medium- versus long-chain fatty acids induce distinct patterns of tissue specific insulin resistance
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8. Pancreatic Fat Content Detected by Computed Tomography and Its Significant Relationship With Intraductal Papillary Mucinous Neoplasm
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10. Grape seed and skin extract reduces pancreas lipotoxicity, oxidative stress and inflammation in high fat diet fed rats
    Faten Aloui, Kamel Charradi, Aziz Hichami, Saravanan Selvakumar, Naim A. Khan, Férid Limam, Ezzedine Aouani · 2016 · Biomedicine & Pharmacotherapy
11. Chlorogenic acid from honeysuckle improves hepatic lipid dysregulation and modulates hepatic fatty acid composition in rats with chronic endotoxin infusion
    Yan Zhou, Zheng Ruan, Yanmei Wen, Yuhui Yang, Shumei Mi, Lili Zhou, Xin Wu, Sheng Li Ding, Zeyuan Deng, Guoyao Wu et al. · 2016 · Journal of Clinical Biochemistry and Nutrition
12. Biochemical, Transcriptional, and Bioinformatic Analysis of Lipid Droplets from Seeds of Date Palm (Phoenix dactylifera L.) and Their Use as Potent Sequestration Agents against the Toxic Pollutant, 2,3,7,8-Tetrachlorinated Dibenzo-p-Dioxin
    Abdulsamie Hanano, Ibrahem Almousally, Mouhnad Shaban, Farzana Rahman, Elizabeth Blée, Denis J. Murphy · 2016 · Frontiers in Plant Science
13. Protective effect of docosahexaenoic acid on lipotoxicity‐mediated cell death in Schwann cells: Implication of PI3K/AKT and mTORC2 pathways
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14. Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice
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15. The Change of Skeletal Muscle Caused by Inflammation in Obesity as the Key Path to Fibrosis: Thoughts on Mechanisms and Intervention Strategies
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16. Canine Geriatric Syndrome: A Framework for Advancing Research in Veterinary Geroscience
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17. Chronic Systemic Low-Grade Inflammation and Modern Lifestyle: The Dark Role of Gut Microbiota on Related Diseases with a Focus on COVID-19 Pandemic
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18. Lipotoxicity-related sarcopenia: a review
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19. Effects of berberine and cinnamic acid on palmitic acid-induced intracellular triglyceride accumulation in NIT-1 pancreatic β cells
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20. Changes in lipid distribution during aging and its modulation by calorie restriction
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21. Impact of abdominal and epicardial fat on the association between plasma adipocytokine levels and coronary atherosclerosis in non-obese patients
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22. Opuntia ficus-indica seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet–fed mice
    Jung‐Woo Kang, Jun-Kyu Shin, Eun‐Ji Koh, Hyojeong Ryu, Hyoung Ja Kim, Sun‐Mee Lee · 2015 · Nutrition Research
23. Hypolipidemic effect of polysaccharides from Fortunella margarita (Lour.) Swingle in hyperlipidemic rats
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24. Magnolia Bioactive Constituent 4-O-Methylhonokiol Prevents the Impairment of Cardiac Insulin Signaling and the Cardiac Pathogenesis in High-Fat Diet-Induced Obese Mice
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25. Fatty Acid Oxidation and Cardiovascular Risk during Menopause: A Mitochondrial Connection?
    Paulo Jorge Oliveira, Rui A. Carvalho, Piero Portincasa, Leonilde Bonfrate, Vilma A. Sardão · 2012 · Journal of Lipids
26. Cardiomyocyte apoptosis in animal models of obesity
    Premal S. Trivedi, Lili A. Barouch · 2008 · Current Hypertension Reports
27. Is there a role for diet in ameliorating the reproductive sequelae associated with chronic low-grade inflammation in polycystic ovary syndrome and obesity?
    Joan K. Riley, Emily S. Jungheim · 2016 · Fertility and Sterility
28. Dietary lipid levels affect lipoprotein clearance, fatty acid transport, lipogenesis and lipolysis at the transcriptional level in muscle and adipose tissue of large yellow croaker (Larimichthys crocea)
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29. Therapy with mesenchymal stromal cells or conditioned medium reverse cardiac alterations in a high-fat diet–induced obesity model
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30. Reversal of high fat diet-induced obesity through modulating lipid metabolic enzymes and inflammatory markers expressions in rats
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31. Pancreatic Steatosis Is Associated with Both Metabolic Syndrome and Pancreatic Stiffness Detected by Ultrasound Elastography
    Orhan Sezgın, Serkan Yaraş, Osman Cavit Ozdogan · 2021 · Digestive Diseases and Sciences
32. Metabolic characteristics of normal weight central obesity phenotype polycystic ovary syndrome women: a large-scale national epidemiological survey
    Liangshan Mu, Yue Zhao, Rong Li, Yu-Chen Lai, Jie Qiao · 2018 · Reproductive BioMedicine Online
33. Antihyperlipidaemic and antioxidant effect of the total flavonoids in Selaginella tamariscina (Beauv.) Spring in diabetic mice
    Xiaoke Zheng, Weiwei Wang, Li Zhang, Cheng-Fu Su, Yong-yong Wu, Yingying Ke, Qing-wei Hou, Zhaoyan Liu, Ai-she Gao, Weisheng Feng · 2013 · Journal of Pharmacy and Pharmacology
34. The herbal extract ALS-L1023 from Melissa officinalis alleviates visceral obesity and insulin resistance in obese female C57BL/6J mice
    Dongju Lee, Yujin Shin, Joonseong Jang, Yong-Hyun Park, Jiwon Ahn, Sunhyo Jeong, Soon Shik Shin, Michung Yoon · 2020 · Journal of Ethnopharmacology
35. SARS-CoV-2 Infection and Pancreatic β Cell Failure
    Keiichiro Mine, Seiho Nagafuchi, Hitoe Mori, Hirokazu Takahashi, Keizo Anzai · 2021 · Biology
36. The Impact of Unbalanced Maternal Nutritional Intakes on Oocyte Mitochondrial Activity: Implications for Reproductive Function
    Gemma Fabozzi, Benedetta Iussig, Danilo Cimadomo, Alberto Vaiarelli, Roberta Maggiulli, Nicolò Ubaldi, Filippo Maria Ubaldi, Laura Francesca Rienzi · 2021 · Antioxidants
37. Branched-chain amino acid modulation of lipid metabolism, gluconeogenesis, and inflammation in a finishing pig model: targeting leucine and valine
    Xinbo Zhou, Junjie Zhang, Jian Shen, Baojing Cheng, Chongpeng Bi, Qingquan Ma · 2023 · Food & Function
38. Cardiac lipid levels show diurnal changes and long‐term variations in healthy human subjects
    Michael Ith, Christoph Stettler, Jian Xu, Chris Boesch, Roland Kreis · 2014 · NMR in Biomedicine
39. Camellia euphlebia flower extract inhibits oleic acid-induced lipid accumulation via reduction of lipogenesis in HepG2 cells
    Dongye He, Ping Zhang, Xuan Sai, Xiaoyu Li, Lili Wang, Yongping Xu · 2017 · European Journal of Integrative Medicine
40. The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish
    Si‐Lan Han, Yan Liu, Samwel Mchele Limbu, Liqiao Chen, Mei‐Ling Zhang, Zhen‐Yu Du · 2020 · Fish Physiology and Biochemistry
41. Pioglitazone ameliorates systolic and diastolic cardiac dysfunction in rat model of angiotensin II-induced hypertension
    Aiko Sakamoto, Makiko Hongo, Kyoko Furuta, Kan Saito, Ryozo Nagai, Nobukazu Ishizaka · 2012 · International Journal of Cardiology
42. Eat and Death: Chronic Over-Eating
    Atilla Engin · 2017 · Advances in experimental medicine and biology
43. Over-expression of PPARα in obese mice adipose tissue improves insulin sensitivity
    Haruya Takahashi, Kohei Sanada, Hiroyuki Nagai, Yongjia Li, Yumeko Aoki, Takeshi Ara, Shigeto Seno, Hideo Matsuda, Rina Yu, Teruo Kawada et al. · 2017 · Biochemical and Biophysical Research Communications
44. Widespread expression of perilipin 5 in normal human tissues and in diseases is restricted to distinct lipid droplet subpopulations
    Merita Hashani, Hagen Roland Witzel, L Pawella, Judith Lehmann‐Koch, Jens Schumacher, Gunhild Mechtersheimer, Martina Schnölzer, Peter Schirmacher, Wilfried Roth, Beate Katharina Straub · 2018 · Cell and Tissue Research
45. The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum , and Ephedra sinica inhibits hepatic steatosis and fibroinflammtion in high-fat diet-induced obese mice
    Jonghoon Lim, Haerim Lee, Jiwon Ahn, Jeongjun Kim, Joonseong Jang, Yong-Hyun Park, Birang Jeong, Heejung Yang, Soon Shik Shin, Michung Yoon · 2018 · Journal of Ethnopharmacology
46. Nonlinear microscopy of lipid storage and fibrosis in muscle and liver tissues of mice fed high-fat diets
    Christian Brackmann, Britt G. Gabrielsson, Fredrik Svedberg, Agneta B. Holmäng, Ann‐Sofie Sandberg, Annika M. K. Enejder · 2010 · Journal of Biomedical Optics
47. Bamboo extract reduces interleukin 6 (IL-6) overproduction under lipotoxic conditions through inhibiting the activation of NF-κB and AP-1 pathways
    Jason K. Higa, Jun Panee · 2011 · Cytokine
48. Loss of pigment epithelium-derived factor leads to ovarian oxidative damage accompanied by diminished ovarian reserve in mice
    Xinghui Li, Haiping Wang, Jing He Tan, Yandi Wu, Ming Wen Ou Yang, Chengzhou Mao, Saifei Gao, Hui Li, Hui Chen, Weibin Cai · 2018 · Life Sciences
49. Nonalcoholic fatty pancreas disease is related independently to the severity of acute pancreatitis
    Jiarong Xie, Lu Xu, Yuning Pan, Peifei Li, Yi Liu, Yue Pan, Keshu Shan, Yu Zhang, Lei Xu · 2019 · European Journal of Gastroenterology & Hepatology
50. A low-intensity lifelong exercise routine changes miRNA expression in aging and prevents osteosarcopenic obesity by modulating inflammation
    Gibrán Pedraza-Vázquez, Beatriz Mena‐Montes, David Hernández-Álvarez, Juan Carlos Gómez-Verján, Rafael Toledo-Pérez, Miriam Teresa López-Teros, Mina Königsberg, Luis Enrique Gómez-Quiroz, Armando Luna‐López · 2022 · Archives of Gerontology and Geriatrics
51. Activation of AMP-Activated Protein Kinase Alleviates Homocysteine-Mediated Neurotoxicity in SH-SY5Y Cells
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52. Follicular Fluid Concentrations of Lipids and Their Metabolites Are Associated With Intraovarian Gonadotropin-Stimulated Androgen Production in Women Undergoing In Vitro Fertilization
    Alexandre Gervais, Marie‐Claude Battista, Belina Carranza‐Mamane, Hélène B. Lavoie, Jean‐Patrice Baillargeon · 2015 · The Journal of Clinical Endocrinology & Metabolism
53. Global Analyses of Selective Insulin Resistance in Hepatocytes Caused by Palmitate Lipotoxicity
    Zhihuan Li, Zon Weng Lai, Romain Christiano, Felipe Gazos‐Lopes, Tobias C. Walther, Robert V. Farese · 2018 · Molecular & Cellular Proteomics
54. Obesity-induced hepatic hypoperfusion primes for hepatic dysfunction after resuscitated hemorrhagic shock
    Paul J. Matheson, Ryan T. Hurt, Glen A. Franklin, Craig James McClain, Richard Neal Garrison · 2009 · Surgery
55. Nervonic acid triggered ovarian inflammation by inducing mitochondrial oxidative stress to activate NLRP3/ IL-1β pathway
    Xiangzhou Zeng, Xinyin Fan, Haitao Yu, Shuang Cai, Liangrui Zhou, Huanwen Wu, Zhiwen Zhang, Shuang Quan, Siyu Li, Xinyu Wang et al. · 2024 · Journal of Advanced Research
56. Hypertension, but not body mass index, is predictive of increased pancreatic lipid content and islet dysfunction
    Daniel M. Tremmel, Austin K. Feeney, Samantha A. Mitchell, Peter J. Chlebeck, Sierra A. Raglin, Luis A. Fernandez, Jon S. Odorico, Sara Dutton Sackett · 2019 · American Journal of Transplantation
57. Dietary Intake of Hydrolyzable Tannins and Condensed Tannins to Regulate Lipid Metabolism
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58. Jiao Tai Wan Attenuates Hepatic Lipid Accumulation in Type 2 Diabetes Mellitus
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59. TheMagnoliaBioactive Constituent 4-O-Methylhonokiol Protects against High-Fat Diet-Induced Obesity and Systemic Insulin Resistance in Mice
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60. Lipid Profiles of Adipose and Muscle Tissues in Mouse Models of Juvenile Onset of Obesity without High Fat Diet Induction: A Fourier Transform Infrared (FT-IR) Spectroscopic Study
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61. Effects of aging and menopause on pancreatic fat fraction in healthy women population
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62. The herbal extract ALS-L1023 from Melissa officinalis reduces weight gain, elevated glucose levels and β-cell loss in Otsuka Long-Evans Tokushima fatty rats
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63. A proline metabolism selection system and its application to the engineering of lipid biosynthesis in Chinese hamster ovary cells
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64. Structural characterization and anti-lipotoxicity effects of a pectin from okra (Abelmoschus esculentus (L.) Moench)
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65. Relation Between Obesity and Type 2 Diabetes: Evolutionary Insights, Perspectives and Controversies
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66. Effect of silymarin on liver phoshpatidate phosphohydrolase in hyperlipidemic rats
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67. Sexual dimorphism in obesity-related genes in the epicardial fat during aging
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68. Intrahepatic fat, abdominal adipose tissues, and metabolic state: magnetic resonance imaging study
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70. Distinct Hepatic Macrophage Populations in Lean and Obese Mice
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71. Elevated non-esterified fatty acids impair survival and promote lipid accumulation and pro-inflammatory cytokine production in bovine endometrial epithelial cells
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72. Nonalcoholic Fatty Liver Disease
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73. FTO Is a Relevant Factor for the Development of the Metabolic Syndrome in Mice
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74. Treatment of cigarette smoke extract and condensate differentially potentiates palmitic acid-induced lipotoxicity and steatohepatitis in vitro
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75. Are we giving too much weight to lean mass loss?
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76. Lipid metabolism disorders of hybrid grouper (♀Epinephelus fuscointestinestatus × ♂E. lanceolatu) induced by high-lipid diet
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77. Lipid-lowering effect of artichoke on liver phosphatidate phosphohydrolase and plasma lipids in hyperlipidemic rats
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78. Nanoemulsions improve the efficacy of turmeric in palmitate- and high fat diet-induced cellular and animal models
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80. Adipose Tissue in Health and Disease
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85. Exercise-induced, but not creatine-induced, decrease in intramyocellular lipid content improves insulin sensitivity in rats
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92. Effects of regular-moderate exercise on high-fat diet-induced intramyocellular lipid accumulation in the soleus muscle of Sprague-Dawley rats
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93. Met-enkephalin improves metabolic syndrome in high fat diet challenged mice through promotion of adipose tissue browning
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94. Free Fatty Acid Overload Targets Mitochondria: Gene Expression Analysis of Palmitic Acid-Treated Endothelial Cells
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95. Partial replacement of high-fat diet with n-3 PUFAs enhanced beef tallow attenuates dyslipidemia and endoplasmic reticulum stress in tunicamycin-injected rats
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96. Ablation of Elovl6 protects pancreatic islets from high-fat diet-induced impairment of insulin secretion
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97. 5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool
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98. The Pivotal Role of the Western Diet, Hyperinsulinemia, Ectopic Fat, and Diacylglycerol-Mediated Insulin Resistance in Type 2 Diabetes
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99. Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice
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100. Postprandial consequences of lipid absorption in the onset of obesity: Role of intestinal CD36
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