Lipid accumulation in non-adipose tissue and lipotoxicity

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Items 101–200 of 500

1. Increasing Fatty Acid Oxidation Remodels the Hypothalamic Neurometabolome to Mitigate Stress and Inflammation
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2. Dynamic regulation of mitochondrial network and oxidative functions during 3T3-L1 fat cell differentiation
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3. Skeletal muscle as a therapeutic target for delaying type 1 diabetic complications
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4. Anti-obesity effects of DHA and EPA in high fat-induced insulin resistant mice
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5. Obesity and dyslipidemia in early life: Impact on cardiometabolic risk
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6. Anti-Obesity Effect of Dictyophora indusiata Mushroom Polysaccharide (DIP) in High Fat Diet-Induced Obesity via Regulating Inflammatory Cascades and Intestinal Microbiome
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7. Skeletal muscle atrophy and dysfunction in obesity and type-2 diabetes mellitus: Myocellular mechanisms involved
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8. Extracts of Scutellaria baicalensis Reduced Body Weight and Blood Triglyceride in db/db Mice
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9. The PLIN4 Variant rs8887 Modulates Obesity Related Phenotypes in Humans through Creation of a Novel miR-522 Seed Site
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10. Effects of dietary lipid level on growth, fatty acid profiles, antioxidant capacity and expression of genes involved in lipid metabolism in juvenile swimming crab, Portunus trituberculatus
    Peng Sun, Min Jin, Lefei Jiao, Óscar Monroig, Juan Carlos Navarro, Douglas Redford Tocher, Mónica Beatriz Betancor, Xuexi Wang, Ye Yuan, Qicun Zhou · 2019 · British Journal Of Nutrition
11. Connecting lipid droplet biology and the metabolic syndrome
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12. Mapping body fat distribution: A key step towards the identification of the vulnerable patient?
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13. Type 2 diabetes: Does pancreatic fat really matter?
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14. Human pancreatic afferent and efferent nerves: mapping and 3-D illustration of exocrine, endocrine, and adipose innervation.
    Hung-Jen Chien, Tsai-Chen Chiang, Shih-Jung Peng, Mei-hsin Chung, Ya-Hsien Chou, Chih-Yuan Lee, Y. Jeng, Tien Yu-Wen, Shiue-Cheng Tang · 2019 · American Journal of Physiology - Gastrointestinal and Liver Physiology
15. Fat Wasting Is Damaging: Role of Adipose Tissue in Cancer-Associated Cachexia
    Xiaoting Sun, Xiaogang Feng, Xiaojing Wu, Yongtian Lu, Kaihong Chen, Ying Ye · 2020 · Frontiers in Cell and Developmental Biology
16. Obesity-alleviating potential of asiatic acid and its effects on ACC1, UCP2, and CPT1 mRNA expression in high fat diet-induced obese Sprague–Dawley rats
    P. Rameshreddy, V. V. Sathibabu Uddandrao, Brahmanaidu Parim, Sasikumar Vadivukkarasi, Ravindarnaik Ramavat, Pothani Suresh, K. Swapna, A. Kalaivani, Parimi Parvathi, Tamilmani Periyasamy et al. · 2017 · Molecular and Cellular Biochemistry
17. Are PPAR alpha agonists a rational therapeutic strategy for preventing abnormalities of the diabetic kidney?
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18. Effects of Pectin Pentaoligosaccharide from Hawthorn (Crataegus pinnatifida Bunge. var. Major) on the Activity and mRNA Levels of Enzymes Involved in Fatty Acid Oxidation in the Liver of Mice Fed a High-Fat Diet
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19. Farnesol, an isoprenoid, improves metabolic abnormalities in mice via both PPARα-dependent and -independent pathways.
    T. Goto, Young-il Kim, K. Funakoshi, Aki Teraminami, Taku Uemura, Shizuka Hirai, Joo-Young Lee, M. Makishima, R. Nakata, H. Inoue et al. · 2011 · American Journal of Physiology. Endocrinology and Metabolism
20. Targeted Disruption of Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 Promotes Diet-Induced Hepatic Steatosis and Insulin Resistance
    Elaine Xu, Marie-Julie Dubois, Nelly Leung, Alexandre Charbonneau, Claire Turbide, Rita Kohen Avramoglu, Luisa DeMarte, Mounib Elchebly, Thomas Streichert, Emile H. Levy et al. · 2009 · Endocrinology
21. Age and sex mediated changes in epicardial fat adipokines
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22. Engineering of Chinese hamster ovary cell lipid metabolism results in an expanded ER and enhanced recombinant biotherapeutic protein production
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23. Impact of obesity on renal structure and function in the presence and absence of hypertension: evidence from melanocortin-4 receptor-deficient mice
    do Carmo, Jussara M., Tallam, Lakshmi S., Roberts, John V., Brandon, Elizabeth L., Biglane, John, da Silva, Alexandre A., Hall, John E. · 2009 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
24. AMPK activation inhibits apoptosis and tau hyperphosphorylation mediated by palmitate in SH-SY5Y cells
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25. Fructose impairs glucose-induced hepatic triglyceride synthesis
    Danshan Huang, Tania Dhawan, Stephen G. Young, William H. Yong, László G. Boros, Anthony P. Heaney · 2011 · Lipids in Health and Disease
26. Role of fatty acid elongase Elovl6 in the regulation of energy metabolism and pathophysiological significance in diabetes
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27. Not all fats are created equal: adipose vs. ectopic fat, implication in cardiometabolic diseases
    Melania Gaggini, Chiara Saponaro, Amalia Gastaldelli · 2015 · Hormone Molecular Biology and Clinical Investigation
28. TNFα gene knockout differentially affects lipid deposition in liver and skeletal muscle of high-fat-diet mice
    Jérôme Salles, Nicolas Tardif, Jean‐François Landrier, Isabelle Mothe‐Satney, Christelle Guillet, Carole Vaysse, Lydie Combaret, Christophe Giraudet, Véronique Patrac, Justine Bertrand‐Michel et al. · 2012 · The Journal of Nutritional Biochemistry
29. Elovl6 Deficiency Improves Glycemic Control in Diabetic db / db Mice by Expanding β-Cell Mass and Increasing Insulin Secretory Capacity
    Hui Zhao, Takashi Matsuzaka, Yuta Nakano, Kaori Motomura, Nie Tang, Tomotaka Yokoo, Yuka Okajima, Song‐iee Han, Yoshinori Takeuchi, Yuichi Aita et al. · 2017 · Diabetes
30. Lactoferrin attenuates high-fat diet-induced hepatic steatosis and lipid metabolic dysfunctions by suppressing hepatic lipogenesis and down-regulating inflammation in C57BL/6J mice
    Ling Hua Xiong, Fazheng Ren, Jiayi Lv, Hao Zhang, Huiyuan Guo · 2018 · Food & Function
31. Gemfibrozil improves lipid metabolism in Nile tilapia Oreochromis niloticus fed a high-carbohydrate diet through peroxisome proliferator activated receptor-α activation
    Yuan Luo, Chun-Ting Hu, Fang Qiao, Xiaodan Wang, Jian G. Qin, Zhen‐Yu Du, Liqiao Chen · 2020 · General and Comparative Endocrinology
32. Management of Comorbid Diabetes Mellitus and Worsening Heart Failure
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33. Gender‐specific differences in the development of sarcopenia in the rodent model of the ageing high‐fat rat
    Kob, Robert, Fellner, Claudia, Bertsch, Thomas, Wittmann, Astrid, Mishura, Daria, Sieber, Cornel C., Fischer, Barbara E., Stroszczynski, Christian, Bollheimer, Cornelius L. · 2015 · Journal of Cachexia, Sarcopenia and Muscle
34. An Overview of Novel Dietary Supplements and Food Ingredients in Patients with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease
    Priscila Silva Figueiredo, Aline Carla Inada, Melina Ribeiro Fernandes, Daniela Granja Arakaki, Karine de Cássia Freitas, Rita de Cássia Avellaneda Guimarães, Valter Aragão do Nascimento, Priscila Aiko Hiane · 2018 · Molecules
35. High levels of dietary stearate promote adiposity and deteriorate hepatic insulin sensitivity
    Sjoerd AA van den Berg, Bruno Guigas, Silvia Bijland, D. Margriet Ouwens, Peter J. Voshol, Rune R. Frants, Louis M. Havekes, Johannes Anthonius Romijn, Ko Willems van Dijk · 2010 · Nutrition & Metabolism
36. Roles of Sphingolipid Metabolism in Pancreatic β Cell Dysfunction Induced by Lipotoxicity
    Julien Véret, Lara Bellini, Paola Giussani, Carl K.‐Y. Ng, Chr̀istophe Magnan, Hervé Le Stunff · 2014 · Journal of Clinical Medicine
37. Effect of ursolic acid and Rosiglitazone combination on hepatic lipid accumulation in high fat diet-fed C57BL/6J mice
    Arjunan Sundaresan, Thangaiyan Radhiga, Kodukkur Viswanathan Pugalendi · 2014 · European Journal of Pharmacology
38. Sarcoglycan Complex
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39. Development of hypertrophic cardiomyopathy in perilipin-1 null mice with adipose tissue dysfunction
    Shangxin Liu, Bin Geng, Liangqiang Zou, Suning Wei, Weiyi Wang, Jingna Deng, Chong Bing Xu, Xiaojing Zhao, Ying Lyu, Xueying Su et al. · 2014 · Cardiovascular Research
40. Selenium supplementation lowers insulin resistance and markers of cardio-metabolic risk in patients with congestive heart failure: a randomised, double-blind, placebo-controlled trial
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41. Electrophilic nitro-oleic acid reverses obesity-induced hepatic steatosis
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42. Domeless receptor loss in fat body tissue reverts insulin resistance induced by a high-sugar diet in Drosophila melanogaster
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43. Contribution of Adipose Tissue to Health Span and Longevity
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44. Liver and Muscle in Morbid Obesity: The Interplay of Fatty Liver and Insulin Resistance
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45. Proinflammatory gene expression and renal lipogenesis are modulated by dietary protein content in obese Zuckerfa/farats
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46. A mitochondrial-targeted ubiquinone modulates muscle lipid profile and improves mitochondrial respiration in obesogenic diet-fed rats
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47. Effect of epicardial adipose tissue on diastolic functions and left atrial dimension in untreated hypertensive patients with normal systolic function
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48. Docosahexaenoic Acid Delivery Systems, Bioavailability, Functionality, and Applications: A Review
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49. 1H-MR spectroscopy for analysis of cardiac lipid and creatine metabolism
    Kiterie M. E. Faller, Craig A. Lygate, Stefan Neubauer, Jürgen E. Schneider · 2012 · Heart Failure Reviews
50. Lipotoxicity and cardiac dysfunction in mammals andDrosophila
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51. Prenatal exposure to bisphenol A alters mouse fetal pancreatic morphology and islet composition
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52. Ferulic acid alleviates lipotoxicity-induced hepatocellular death through the SIRT1-regulated autophagy pathway and independently of AMPK and Akt in AML-12 hepatocytes
    Tiantian Xu, Qing Song, Li Zhou, Wenwen Yang, Xiangyao Wu, Qianyu Qian, Hui Chai, Qiang Han, Hongzhi Pan, Xiaobing Dou et al. · 2021 · Nutrition & Metabolism
53. Protective potentials of wild rice (Zizania latifolia (Griseb) Turcz) against obesity and lipotoxicity induced by a high-fat/cholesterol diet in rats
    Shu-Fen Han, Hong Zhang, Chengkai Zhai · 2012 · Food and Chemical Toxicology
54. Low density lipoprotein receptor-related protein 1 expression correlates with cholesteryl ester accumulation in the myocardium of ischemic cardiomyopathy patients
    Roi Cal, Oriol Juan‐Babot, Vicenç Brossa, Santiago Roura, Carolina Gálvez‐Montón, Manuel Portolés, Miguel Rivera, Juan Cinca A, Lina Badimón, Vicenta Llorente‐Cortés · 2012 · Journal of Translational Medicine
55. Antihyperlipidaemic and hepatoprotective activities of acidic and enzymatic hydrolysis exopolysaccharides from Pleurotus eryngii SI-04
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56. Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats
    Mohammad H. Abukhalil, Omnia E. Hussein, May Nasser Bin-Jumah, Sultan Ayesh Mohammed Saghir, Mousa O. Germoush, Hassan A. Elgebaly, Nermeen M. Mosa, İsmail Hamad, Moath M. Qarmush, Emad H. M. Hassanein et al. · 2020 · Environmental Science and Pollution Research
57. m6A modification impacts hepatic drug and lipid metabolism properties by regulating carboxylesterase 2
    Seiya Takemoto, Masataka Nakano, Tatsuki Fukami, Miki Nakajima · 2021 · Biochemical Pharmacology
58. The effect of a single 2 h bout of aerobic exercise on ectopic lipids in skeletal muscle, liver and the myocardium
    J. Bucher, Marion Krüsi, T. Zueger, M. Ith, C. Stettler, P. Diem, C. Boesch, R. Kreis, E. Christ · 2014 · Diabetologia
59. Polysaccharide from Rubus chingii Hu affords protection against palmitic acid-induced lipotoxicity in human hepatocytes
    Huihui Ke, Tao Bao, Wei Chen · 2019 · International Journal of Biological Macromolecules
60. The intrinsic and extrinsic elements regulating inflammation
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61. Extracting quantitative biological information from bright-field cell images using deep learning
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62. The role of protein kinases as key drivers of metabolic dysfunction-associated fatty liver disease progression: New insights and future directions
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63. Effects ofPiper nigrumextracts: Restorative perspectives of high-fat diet-induced changes on lipid profile, body composition, and hormones in Sprague–Dawley rats
    Brahmanaidu Parim, Harishankar Nemani, Balaji Meriga, Sailaja Pothana, Ramgopal Rao Sajjalaguddam · 2015 · Pharmaceutical Biology
64. Metabolic effects of berberine on liver phosphatidate phosphohydrolase in rats fed on high lipogenic diet: an additional mechanism for the hypolipidemic effects of berberine
    Esfandiar Heidarian, Mahmoud Rafieian‐Kopaei, Abolfazl Khoshdel, Morteza Bakhshesh · 2014 · Asian Pacific Journal of Tropical Biomedicine
65. Can pancreatic steatosis affect exocrine functions of pancreas?
    Mustafa Tahtacı, Oktay Algın, Tarkan Karakan, Öykü Tayfur Yürekli, Murat Alışık, Hüseyin Köseoğlu, Melike Ruşen Metin, Aylin DEMİREZER BOLAT, Özcan Erel, Osman Ersoy · 2018 · The Turkish Journal of Gastroenterology
66. A review of the studies on food-derived factors which regulate energy metabolism via the modulation of lipid-sensing nuclear receptors
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67. Effects of dietary lipid levels on growth, fatty acid composition, antioxidant status and lipid metabolism in juvenileOnychostoma macrolepis
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68. Skeletal Muscle as a Mediator of Interorgan Crosstalk During Exercise: Implications for Aging and Obesity
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69. Increasing Protein Intake Modulates Lipid Metabolism in Healthy Young Men and Women Consuming a High-Fat Hypercaloric Diet
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70. A Functional, Genome-wide Evaluation of Liposensitive Yeast Identifies the “RE2 Required for Viability” (ARV1) Gene Product as a Major Component of Eukaryotic Fatty Acid Resistance
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71. PEDF and PEDF-derived peptide 44mer stimulate cardiac triglyceride degradation via ATGL
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72. Auranofin Attenuates Non-Alcoholic Fatty Liver Disease by Suppressing Lipid Accumulation and NLRP3 Inflammasome-Mediated Hepatic Inflammation In Vivo and In Vitro
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73. Steatosis in the Liver
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74. Treatment of Rats with a Self-Selected Hyperlipidic Diet, Increases the Lipid Content of the Main Adipose Tissue Sites in a Proportion Similar to That of the Lipids in the Rest of Organs and Tissues
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75. Lkb1 Deletion Promotes Ectopic Lipid Accumulation in Muscle Progenitor Cells and Mature Muscles
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76. Mdivi-1 Protects Adult Rat Hippocampal Neural Stem Cells against Palmitate-Induced Oxidative Stress and Apoptosis
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77. Antioxidant Versus Pro-Apoptotic Effects of Mushroom-Enriched Diets on Mitochondria in Liver Disease
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78. Fatty infiltration in the musculoskeletal system: pathological mechanisms and clinical implications
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79. Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway
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80. Endurance exercise prevents high-fat-diet induced heart and mobility premature aging and dsir2 expression decline in aging Drosophila
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81. Morchella esculenta polysaccharide attenuate obesity, inflammation and modulate gut microbiota
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82. Hyperlipidemia and Hyperinsulinemia in the Spontaneous Osteoarthritis Mouse Model, STR/Ort
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83. Lipotoxicity of palmitic acid is associated with DGAT1 downregulation and abolished by PPARα activation in liver cells
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84. Therapeutic effect of natural melanin from edible fungus Auricularia auricula on alcohol-induced liver damage in vitro and in vivo
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85. Cinnamomum cassiaPrevents High-Fat Diet-Induced Obesity in Mice through the Increase of Muscle Energy
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86. Serum metabolic variables associated with impaired glucose tolerance induced by high-fat-high-cholesterol diet in <i>Macaca mulatta</i>
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87. Mechanism of Obesity-Related Lipotoxicity and Clinical Perspective
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88. l-Carnitine intake prevents irregular feeding-induced obesity and lipid metabolism disorder
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89. The macrophage at the intersection of immunity and metabolism in obesity
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90. Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis
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91. Hydrogen Nano-Bubble Water Suppresses ROS Generation, Adipogenesis, and Interleukin-6 Secretion in Hydrogen-Peroxide- or PMA-Stimulated Adipocytes and Three-Dimensional Subcutaneous Adipose Equivalents
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92. The effect of isosteviol on hyperglycemia and dyslipidemia induced by lipotoxicity in rats fed with high-fat emulsion
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93. Hepatic BSCL2 (Seipin) Deficiency Disrupts Lipid Droplet Homeostasis and Increases Lipid Metabolism via SCD1 Activity
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94. Oleic acid-induced ADRP expression requires both AP-1 and PPAR response elements, and is reduced by Pycnogenol through mRNA degradation in NMuLi liver cells
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95. The Flexibility of Ectopic Lipids
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96. Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas
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97. Mir-152 Regulates 3T3-L1 Preadipocyte Proliferation and Differentiation
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98. Sex-dependent differences in rat hepatic lipid accumulation and insulin sensitivity in response to diet-induced obesity
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99. Quantification of ectopic fat storage in the liver and pancreas using six-point Dixon MRI and its association with insulin sensitivity and β-cell function in patients with central obesity
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100. Foenumoside B from Lysimachia foenum-graecum inhibits adipocyte differentiation and obesity induced by high-fat diet
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