Obesity in Pregnancy Stimulates Macrophage Accumulation and Inflammation in the Placenta

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2. Autism spectrum disorders in extremely preterm infants and placental pathology findings: a matched case–control study
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3. Tacrolimus in the prevention of adverse pregnancy outcomes and diabetes-associated embryopathies in obese and diabetic mice
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4. CELL BIOLOGY SYMPOSIUM: Impacts of maternal obesity on placental and gut inflammation and health1,2
   Maobi Zhu, ‬Min Du, Stephen P. Ford · 2013 · Journal of Animal Science
5. Embryonic programming of heart disease in response to obesity during pregnancy
   Abdalla Ahmed, Paul Delgado-Olguı́n · 2019 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
6. Maternal obesity, diabetes mellitus and cord blood biomarkers in large-for-gestational age infants
   Fengxiu Ouyang, Nana Matoba, Colleen Pearson, Katherin Ortiz, Xiaobin Wang, Karen K.L. Mestan · 2016 · Journal of Pediatric Biochemistry
7. Inflammatory response in visceral fat tissue and liver is prenatally programmed: experimental research.
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8. Epigénétique et Nutrition : impacts de l’alimentation maternelle sur le développement placentaire et la santé de la descendance
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9. Metabolic Syndrome and Preeclampsia
   Carl A. Hubel, James Michael Roberts · 2009 · Elsevier eBooks
10. Slit2 E xerts Anti‐Inflammatory Actions in Human Placenta and is Decreased with Maternal Obesity
    Ratana Lim, Martha Lappas · 2014 · American Journal of Reproductive Immunology
11. Diet Modification before or during Pregnancy on Maternal and Foetal Outcomes in Rodent Models of Maternal Obesity
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12. The immune landscape of fetal chorionic villous tissue in term placenta
    Brianna M. Doratt, Heather True, Suhas Sureshchandra, Qi Qiao, Monica P. Rincon, Nicole Marshall, Ilhem Messaoudi · 2025 · Frontiers in Immunology
13. Effect of Obesity on the Acute Inflammatory Response in Pregnant and Cycling Female Rats
    Joanna Pohl, Giamal N. Luheshi, Barbara Christine Woodside · 2013 · Journal of Neuroendocrinology
14. Low-intensity Physical Activity is Associated with Lower Maternal Systemic Inflammation during Late Pregnancy
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15. Placental Ras Regulates Inflammation Associated with Maternal Obesity
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16. Enhancement of placental inflammation by Dibutyl Phthalate
    Aisha Manna Alsubaie, Yuko Arita, Matthew Atwater, Ali Mahfuz, Morgan R. Peltier · 2021 · Journal of Reproductive Immunology
17. Association Between Obesity and Fetal Acidosis at Scheduled Cesarean Delivery
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18. The predictive value of the uterine artery pulsatility index during the early third trimester for the occurrence of adverse pregnancy outcomes depending on the maternal obesity
    Yeon Hee Kim, Hee Joung Lee, Jae Eun Shin, Young Ho Lee, Jong Chul Shin, Tae Chul Park, In Yang Park · 2014 · Obesity Research & Clinical Practice
19. Key Clinical Factors Predicting Adipokine and Oxidative Stress Marker Concentrations among Normal, Overweight and Obese Pregnant Women Using Artificial Neural Networks
    Juan Mario Solis‐Paredes, Guadalupe Estrada‐Gutiérrez, Otilia Perichart‐Perera, Araceli Montoya-Estrada, Mario Guzmán‐Huerta, Héctor Jesús Borboa-Olivares, Eyerahí Bravo-Flores, Arturo Cardona-Pérez, Verónica Zaga‐Clavellina, Ethel Garcı́a-Latorre et al. · 2017 · International Journal of Molecular Sciences
20. New views on endothelial dysfunction in gestational hypertension and potential therapy targets
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21. The interleukins IL-6 and IL-1Ra: a mediating role in the associations between BMI and birth weight?
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22. TNFα-Induced Oxidative Stress and Mitochondrial Dysfunction Alter Hypothalamic Neurogenesis and Promote Appetite Versus Satiety Neuropeptide Expression in Mice
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23. Dysregulation of Placental Lipid Hydrolysis by High-Fat/High-Cholesterol Feeding and Gestational Diabetes Mellitus in Mice
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24. Influence of Pre-Pregnancy Obesity on Carbohydrate and Lipid Metabolism with Selected Adipokines in the Maternal and Fetal Compartment
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25. Placental pathology and fetal growth outcomes in pregnancies complicated by maternal obesity
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26. Placental gene expression of inflammatory markers and growth factors – a case control study of obese and normal weight women
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27. The placental gateway of maternal transgenerational epigenetic inheritance
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28. Marine Omega-3 Fatty Acids, Complications of Pregnancy and Maternal Risk Factors for Offspring Cardio-Metabolic Disease
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29. Heat Shock Proteins as a Potential Therapeutic Target in the Treatment of Gestational Diabetes Mellitus: What We Know so Far
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30. Examining the role of pre‐pregnancy weight and gestational weight gain in allergic disease development among offspring: A population‐based cohort study in Ontario, Canada
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31. The relationship between placental thickness and gestational age in pregnant women: A cross‐sectional study
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32. Obesity and recurrent spontaneous abortion: the crucial role of weight management in pregnancy
    Ruiqi Wang, Zhimin Deng, Gantao Chen, Fangfang Dai, Liangbin Xia · 2025 · Reproductive Biology and Endocrinology
33. Environmental Forces that Shape Early Development: What We Know and Still Need to Know
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34. Placental function and structure at term is altered in broodmares fed with cereals from mid-gestation
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35. CHARACTERISTICS OF CD68+ AND CD163+ EXPRESSION IN PLACENTA OF WOMEN WITH PREECLAMPSIA AND OBESITY
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36. Maternal and Child Health, Non-Communicable Diseases and Metabolites
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37. Extracellular vesicle-mediated targeting strategies for long-term health benefits in gestational diabetes
    Soumyalekshmi Nair, Valeska Ormazábal, Flavio Carrión, Aase Handberg, David H. McIntyre, Carlos Salomón · 2023 · Clinical Science
38. Do all roads lead to Rome? The role of neuro-immune interactions before birth in the programming of offspring obesity
    Christine Louise Jasoni, Tessa R. Sanders, Dong Won Kim · 2015 · Frontiers in Neuroscience
39. Effect of maternal high-fat diet on key components of the placental and hepatic endocannabinoid system
    Kushal Gandhi, Cun Li, Nadezhda German, Cezary Skobowiat, Maira Carrillo, Raja Reddy Kallem, Eneko Larumbe‐Zabala, Stacy Martinez, Marcel A. Chuecos, Gary Ventolini et al. · 2017 · American Journal of Physiology-Endocrinology and Metabolism
40. Effects of troxerutin on inflammatory cytokines and BDNF levels in male offspring of high-fat diet fed rats.
    Maryam Hosseindoost, Mohammad Reza Alipour, Fereshteh Farajdokht, Roghayeh Diba, Parvin Bayandor, Keyvan Mehri, Sepehr Nayebirad, Shirin Babri · 2019 · Europe PMC (PubMed Central)
41. Associations of Body Mass Index and Gestational Weight Gain with Term Pregnancy Outcomes
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42. Nurturing development: how a mother's nutrition shapes offspring's brain through the gut
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43. The impact of obesity on mitochondrial dysfunction during pregnancy
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44. Effect of Polyphenols Intake on Obesity-Induced Maternal Programming
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45. Preterm Birth Associates With Increased Placental Expression of MDR Transporters Irrespective of Prepregnancy BMI
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46. Metformin Impacts Human Syncytiotrophoblast Mitochondrial Function from Pregnancies Complicated by Obesity and Gestational Diabetes Mellitus in a Sexually Dimorphic Manner
    Jessica F. Hebert, Leslie Myatt · 2023 · Antioxidants
47. Maternal pre-pregnancy obesity affects the uncinate fasciculus white matter tract in preterm infants
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48. Maternal obesity: how big an impact does it have on offspring prenatally and during postnatal life?
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49. Dynamics and reproductive effects of complement factors in the spontaneous abortion model of CBA/J × DBA/2 mice
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50. Maternal Magnesium Restriction Elevates Glucocorticoid Stress and Inflammation in the Placenta and Fetus of WNIN Rat Dams
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51. Nuclear Magnetic Resonance-Assisted Metabolic Analysis of Plasma for Mild Gestational Diabetes Mellitus Patients
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52. Prepregnancy obesity and risk of placental inflammation at term: a selection bias analysis
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53. The Role of the Intrauterine Environment in Shaping Childhood and Adolescence Metabolic Outcomes
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54. Maternal high-fat, high-sucrose diet–induced excess adiposity is linked to placental hypoxia and disruption of fetoplacental immune homeostasis in late gestation
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55. The Mother–Child Dyad Adipokine Pattern: A Review of Current Knowledge
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56. Metformin and dietary advice to improve insulin sensitivity and promote gestational restriction of weight among pregnant women who are overweight or obese: the GRoW Randomised Trial
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57. The Potential Benefit of Hydroxychloroquine in Chronic Placental Inflammation of Unknown Etiology Associated with Adverse Pregnancy Outcomes
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58. Maternal obesity attenuates predelivery inflammatory reaction in C57BL/6N mice
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59. Dietary curcumin supplementation ameliorates placental inflammation in rats with intra-uterine growth retardation by inhibiting the NF-κB signaling pathway
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60. Maternal Overnutrition and Fetal Programming: Long-Term Metabolic, Cognitive, and Epigenetic Consequences
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61. Palmitoleate protects against lipopolysaccharide-induced inflammation and inflammasome activity
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62. Role of macrophages reprogramming in pathogenesis of gestational diabetes mellitus
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63. Evaluation of serum neopterin, periostin, Tenascin‐C, tissue inhibitor of metalloproteinase-1 and matrix metalloproteinase-2 levels in obese pregnant women
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64. Maternal Metabolic Biomarkers are Associated with Obesity and Excess Gestational Weight Gain
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65. NURR1 Alterations in Perinatal Stress: A First Step towards Late-Onset Diseases? A Narrative Review
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66. Sexual Dimorphism in the Closure of the Hippocampal Postnatal Critical Period of Synaptic Plasticity after Intrauterine Growth Restriction: Link to Oligodendrocyte and Glial Dysregulation
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67. Cellular inhibitors of apoptosis (cIAP) 1 and 2 are increased in placenta from obese pregnant women
    Martha Lappas · 2014 · Placenta
68. Maternal Obesity and Placental Oxidative Stress in the First Trimester
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69. Endocrine Diseases of Pregnancy
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70. Associations of Placental Inflammation and Oxidative Stress Biomarkers with Glucolipid Metabolism in Children: A Birth Cohort Study in China
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71. Macrophage Switching in Pregnancy: Regulatory Mechanisms Governing Term Labour and Preterm Birth
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72. Liver X Receptor Activation Attenuates Oxysterol-Induced Inflammatory Responses in Fetoplacental Endothelial Cells
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73. Association of maternal pre-pregnancy body mass index with birth weight and preterm birth among singletons conceived after frozen-thawed embryo transfer
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74. Does Maternal Obesity Affect Preterm Birth? Documentary Cohort Study of Preterm in Firstborns—Silesia (Poland)
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75. Maternal Obesity and Pregnancy
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76. Tumor necrosis factor‐alpha levels in blood cord is directly correlated with the body weight of mothers
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77. Neopterin and hsCRP are not correlated in gestational diabetes mellitus
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78. The Effects of Body Mass Index on Second-Trimester Amniotic Fluid Cytokine and Matrix Metalloproteinase Levels
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79. Placental Pim-1 expression is increased in obesity and regulates cytokine- and toll-like receptor-mediated inflammation
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80. Maternal Nutrition and Child Neurodevelopment: Actions Across Generations
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81. Gestational Weight Gain and Offspring Bone Mass: Different Associations in Healthy Weight Versus Overweight Women
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82. Maternal Overweight, Inflammation and Neurological Consequences for the Preterm Child: Results of the ELGAN Study
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83. The “Great Obstetrical Syndromes”
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84. Prenatal exposure to maternal hypertension and higher body mass index and risks of neurodevelopmental and psychiatric disorders during childhood
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85. Impacts of maternal excess adiposity on the uterine immune environment: contributions to placental dysfunction and adverse pregnancy outcomes
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86. The impact of maternal systemic diseases on the occurrence of cleft lip and palate in newborns: a narrative review
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87. The impact of obesity on placental vascular development and function
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88. Association of Parity With Insulin Resistance Early in Pregnant Women: ECLIPSES Study
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89. Palmitic acid induces inflammatory cytokines and regulates tRNA-derived stress-induced RNAs in human trophoblasts
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90. Maternal obesity-related placental dysfunction: From peri-conception to late gestation
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91. Maternal obesity is not associated with increased crown-rump length in first-trimester ultrasounds of singleton gestations
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92. Metabolic Syndrome and Preeclampsia
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93. Abdominal visceral adiposity influences CD4+ T cell cytokine production in pregnancy
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94. Impact de l’obésité et du diabète maternels sur la fonction placentaire
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95. Metabolic reprogramming of fetal hematopoietic stem and progenitor cells by maternal obesity
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96. High-fat diet induces pre-eclampsia through dampening cell-autonomous C3 in trophoblasts
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97. Higher Maternal Body Mass Index Is Associated With Lower Placental Expression ofEPYC:A Genome-Wide Transcriptomic Study
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98. Placental microRNA Expression Is Not Altered by Maternal Obesity and Fetal Overgrowth
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99. Treatment of high fat diet‐induced obese pregnant mice with IL‐6 receptor antibody does not ameliorate placental function and fetal growth restriction
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