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Cited by 89Plant-Microbe Interactions and ImmunityInsect-Plant Interactions and ControlImmune Response and Inflammation

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False idolatry of the mythical growth versus immunity tradeoff in molecular systems plant pathology

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Kliebenstein, Daniel J.·2016·Physiological and Molecular Plant Pathology
DOI 10.1016/j.pmpp.2016.02.004
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Abstract

Systems studies of signal transduction pathways that modulate plant growth and immunity are rapidly identifying a large number of interactions within these pathways. These interactions are frequently presented as mechanisms allowing a plant to make proper decisions with regards to how to partition energy and resources in a proposed growth versus immunity tradeoff. This is a reinterpretation of the classical costs of resistance theory that has a long history in the ecology research community. While the ecology community is reinterpreting this theory, the reinterpretation has not been introduced into the molecular systems biology community that is studying the intersection of regulatory pathways. In this article, I describe evidence against a simple growth versus immunity tradeoff concept and propose an alternative wherein the intersection of these regulatory pathways is instead designed to coordinate these pathways, and not simply link them in mutual antagonism, to optimize fitness in complex environments where resistance/immunity and growth do not have simple linear relationships with fitness.

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Metadata

Authors
Kliebenstein, D. J.
Affiliations
University of Copenhagen (DK)
Corresponding author
Kliebenstein, Daniel J.
ORCID
Kliebenstein, Daniel J.
Venue
Physiological and Molecular Plant Pathology
Publisher
Elsevier BV
Published
2016-07
Volume
95
Pages
55-59
ISSN
0885-5765 (ISSN-L)
DOI
10.1016/j.pmpp.2016.02.004
OpenAlex
W2266514286
Cited by
89
References
0
Citations by year
2026: 7 · 2025: 6 · 2024: 12 · 2023: 4 · 2022: 10 · 2021: 12 · 2020: 10 · 2019: 7 · 2018: 7 · 2017: 10 · 2016: 3
FWCI
10.54
Type
journal article
Language
en
Open access
Licence
Locations
  • Physiological and Molecular Plant Pathology (acceptedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Funders
  • National Science Foundation (IOS 1339125, MCB 1330337)
  • Danmarks Grundforskningsfond (DNRF99)
  • National Institute of Food and Agriculture (CA-D-PLS-7033-H)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant-Microbe Interactions and Immunity
  • Life Sciences › Agricultural and Biological Sciences › Insect Science › Insect-Plant Interactions and Control
  • Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
Keywords
fitness cost of resistance, plant signaling, plant immunity, plant growth, resource allocation, systems biology, plant-pathogen interaction, fitness maximization

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