The DOI matches its Crossref record; 116 of the 116 references it cites were found in a registry or an index.
The silent epidemic of chronic pain in older adults
Open accessAbstract
Chronic pain is highly prevalent among older adults where it is associated with significant suffering, disability, social isolation, and greater costs and burden to health care systems. Pharmaceutical treatment of chronic pain in older adults is usually only partially effective and is often limited by side effects including urinary retention, constipation, sedation, cognitive impairment, and increased risk of falls. Since older adults are underrepresented in clinical trials testing treatments for chronic pain, the potential impacts of polypharmacy and frailty on reported outcomes and side effect profiles are largely unknown. Thus, for current treatments providers and patients must balance anticipated benefits of pain reduction with the known and unknown risks of treatment. Chronic pain is also a risk factor for premature death as well as accelerated cognitive decline, suggesting potential shared mechanisms between persistent pain (or its treatment) and dementia. Cognitive decline and dementia may also impact pain perception and the ability to report pain, complicating treatment decisions. Associations between persistent pain and the risks of premature death and accelerated cognitive decline make estimates for chronic pain in these populations particularly challenging. Future research is needed to improve estimates for chronic pain in older adults, to elucidate underlying mechanisms of pain with aging, and to develop and advance safer, more effective treatment options for chronic pain in older adults.
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What is polypharmacy? A systematic review of definitions
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CDC Guideline for Prescribing Opioids for Chronic Pain — United States, 2016
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Cited by
A biopsychosocial model of chronic pain for older adults
Miaskowski, C., Blyth, F., Nicosia, F., Haan, M., Keefe, F., Smith, A., & Ritchie, C. (2020) · Pain Medicine · doi:10.1093/pm/pnz329 · Cited by 159
Neurophysiological Mechanisms Supporting Mindfulness Meditation–Based Pain Relief: an Updated Review
Jinich-Diamant, A., Garland, E., Baumgartner, J., Gonzalez, N., Riegner, G., Birenbaum, J., Case, L., & Zeidan, F. (2020) · Current Pain and Headache Reports · doi:10.1007/s11916-020-00890-8 · Cited by 69
Paracetamol for Multimodal Analgesia
Freo, U. (2022) · Pain Management · doi:10.2217/pmt-2021-0116 · Cited by 46
Dy, M., Olazo, K., Lisker, S., Brown, E., Saha, A., Weinberg, J., & Sarkar, U. (2023) · Journal of Medical Internet Research · doi:10.2196/40044 · Cited by 17
Dumain, M., Jaglin, P., Wood, C., Rainville, P., Pageaux, B., Perrochon, A., Lavallière, M., Vendeuvre, T., David, R., Langlois, P., et al. (2022) · Pain Management Nursing · doi:10.1016/j.pmn.2021.06.005 · Cited by 15
Metadata
- Authors
- Domenichiello, A. F., & Ramsden, C. E.
- Venue
- Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Publisher
- Elsevier BV
- Published
- 2019-07
- Volume
- 93
- Pages
- 284-290
- ISSN
- 0278-5846 (ISSN-L)
- OpenAlex
- W2939881801
- Cited by
- 434
- References
- 116
- FWCI
- 31.69
- Type
- journal article
- Language
- en
- Open access
- green
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- Domenichiello, A. F., & Ramsden, C. E. (2019). The silent epidemic of chronic pain in older adults. Progress in Neuro-Psychopharmacology and Biological Psychiatry. https://doi.org/10.1016/j.pnpbp.2019.04.006
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
