Effect of porosity on long-term degradation of poly (ε-caprolactone) scaffolds and their cellular response
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The optimal porosity for PCL scaffolds should be greater than 90% to effectively control the rate of degradation and provide an appropriate environment for cell attachment, proliferation, and subsequent differentiation.
“Studies have described that the optimal porosity for PCL scaffolds should be greater than 90% to effectively control the rate of degradation and provide an appropriate environment for cell attachment, proliferation, and subsequent differentiation [12].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [12]
Fossil-based polymers have good mechanical properties and thermal resistance compared to natural polymers.
“They can be produced in reproducible high quality and purity. In addition, they have good mechanical properties and thermal resistance compared to natural polymers [12].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [12]
Fossil-based polymers can be produced in reproducible high quality and purity.
“They can be produced in reproducible high quality and purity. In addition, they have good mechanical properties and thermal resistance compared to natural polymers [12].”
From Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review (2023) · cites this paper as [12]
Cites
Biodegradable synthetic polymers for tissue engineering
CSIRO Molecular Science, B. 1., & Gunatillake, P. (2003) · European Cells and Materials · doi:10.22203/ecm.v005a01 · Cited by 1,765 · see citing works
Lam, C. X. F., Savalani, M. M., Teoh, S.-H., & Hutmacher, D. W. (2008) · Biomedical Materials · doi:10.1088/1748-6041/3/3/034108 · Cited by 444 · see citing works
Huang, M.-H., Li, S., & Vert, M. (2004) · Polymer · doi:10.1016/j.polymer.2004.10.054 · Cited by 222 · see citing works
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Degradation mechanisms of polycaprolactone in the context of chemistry, geometry and environment
Bartnikowski, M., Dargaville, T. R., Ivanovski, S., & Hutmacher, D. W. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2019.05.004 · Cited by 769 · see citing works
Resorbable Biomaterials Used for 3D Scaffolds in Tissue Engineering: A Review
Vach Agocsova, S., Culenova, M., Birova, I., Omanikova, L., Moncmanova, B., Danisovic, L., Ziaran, S., Bakos, D., & Alexy, P. (2023) · Materials · doi:10.3390/ma16124267 · Cited by 98 · see citing works
- Authors
- Zhang, Q., Jiang, Y., Zhang, Y., Ye, Z., Tan, W., & Lang, M.
- Affiliations
- East China University of Science and Technology (CN)
- Zhejiang University of Technology (CN)
- Corresponding author
- Zhang, Yan
- Lang, Meidong
- Venue
- Polymer Degradation and Stability
- Publisher
- Elsevier BV
- Published
- 2013-01
- Volume
- 98
- Issue
- 1
- Pages
- 209-218
- ISSN
- 0141-3910 (ISSN-L)
- OpenAlex
- W1975449661
- Cited by
- 102
- References
- 3
- Citations by year
- 2026: 7 · 2025: 22 · 2024: 13 · 2023: 10 · 2022: 6 · 2021: 7 · 2020: 7 · 2019: 7 · 2018: 2 · 2017: 4 · 2016: 4 · 2015: 3 · 2014: 8 · 2013: 2
- FWCI
- 2.25
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Polymer Degradation and Stability (publishedVersion)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Keywords
- polycaprolactone, porous scaffolds, porosity, long-term degradation, compressive modulus, molecular weight reduction, weight loss, structural collapse, cell infiltration, tissue engineering scaffolds
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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