Degradation mechanisms of polycaprolactone in the context of chemistry, geometry and environment
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In alkaline high pH, mass loss appears in the initial stage and degradation rate is linear.
“Under these conditions, the mass loss appears in the initial stage and the degradation rate are linear [46,47].”
From A strategy to tailor the mechanical and degradation properties of PCL-PEG-PCL based copolymers for biomedical application (2023) · cites this paper as [46]
PCL degrades by surface erosion in an alkaline environment with high pH.
“However, the degradation mechanism of PCL in the alkaline environment with high pH is surface erosion.”
From A strategy to tailor the mechanical and degradation properties of PCL-PEG-PCL based copolymers for biomedical application (2023) · cites this paper as [46]
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- Authors
- Bartnikowski, M., Dargaville, T. R., Ivanovski, S., & Hutmacher, D. W.
- Affiliations
- The University of Queensland (AU)
- Queensland University of Technology (AU)
- Corresponding author
- Ivanovski, Sašo
- Hutmacher, Dietmar W.
- Venue
- Progress in Polymer Science
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 96
- Pages
- 1-20
- ISSN
- 0079-6700 (ISSN-L)
- OpenAlex
- W2947075584
- Cited by
- 769
- References
- 145
- Citations by year
- 2026: 101 · 2025: 175 · 2024: 144 · 2023: 125 · 2022: 105 · 2021: 65 · 2020: 47 · 2019: 7
- FWCI
- 15.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Progress in Polymer Science (publishedVersion)
- Griffith Research Online (submittedVersion)
- Funders
- National Health and Medical Research Council (APP1086181)
- Australian Research Council (FT150100408)
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Physical Sciences › Materials Science › Biomaterials › Magnesium Alloys: Properties and Applications
- Physical Sciences › Engineering › Biomedical Engineering › Bone Tissue Engineering Materials
- Keywords
- polycaprolactone, biodegradable polymers, polymer degradation mechanisms, molecular weight reduction, crystallinity, polymer composites, enzymatic degradation, pH-responsive degradation, temperature effects on degradation, phagocytosis, mechanical properties, biomedical applications, sustainable packaging
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