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Hydrogels in drug delivery: Progress and challenges
Open accessAbstract
There has been considerable progress in recent years in addressing the clinical and pharmacological limitations of hydrogels for drug delivery applications but substantial challenges remain. Here we discuss recent progress in overcoming these challenges, particularly with regards to effectively delivering hydrogels inside the body without implantation, prolonging the release kinetics of drugs from hydrogels, and expanding the nature of drugs which can be delivered using hydrogel-based approaches.
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Cited by
Biomedical applications of hydrogels: A review of patents and commercial products
Caló, E., & Khutoryanskiy, V. V. (2015) · European Polymer Journal · doi:10.1016/j.eurpolymj.2014.11.024 · Cited by 2,634
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
Sun, T., Zhang, Y. S., Pang, B., Hyun, D. C., Yang, M., & Xia, Y. (2014) · Angewandte Chemie International Edition · doi:10.1002/anie.201403036 · Cited by 2,164
Designing Cell-Compatible Hydrogels for Biomedical Applications
Seliktar, D. (2012) · Science · doi:10.1126/science.1214804 · Cited by 1,923
Controlled Drug Delivery Systems: Current Status and Future Directions
Adepu, S., & Ramakrishna, S. (2021) · Molecules · doi:10.3390/molecules26195905 · Cited by 1,691
Polymers for Drug Delivery Systems
Liechty, W. B., Kryscio, D. R., Slaughter, B. V., & Peppas, N. A. (2010) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-073009-100847 · Cited by 1,608
Metadata
- Authors
- Hoare, T. R., & Kohane, D. S.
- Venue
- Polymer
- Publisher
- Elsevier BV
- Published
- 2008-04
- Volume
- 49
- Issue
- 8
- Pages
- 1993-2007
- ISSN
- 0032-3861 (ISSN-L)
- OpenAlex
- W2074630757
- Cited by
- 3,776
- References
- 0
- FWCI
- 33.63
- Type
- journal article
- Language
- en
- Open access
- hybrid
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