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Cited by 585

The DOI matches its Crossref record; 429 of the 429 references it cites were found in a registry or an index.

Functional architecture of the retina: Development and disease

Open access
Hoon, Mrinalini, Okawa, Haruhisa, Della Santina, Luca, Wong, Rachel O.L.·2014·Progress in Retinal and Eye Research

Abstract

Structure and function are highly correlated in the vertebrate retina, a sensory tissue that is organized into cell layers with microcircuits working in parallel and together to encode visual information. All vertebrate retinas share a fundamental plan, comprising five major neuronal cell classes with cell body distributions and connectivity arranged in stereotypic patterns. Conserved features in retinal design have enabled detailed analysis and comparisons of structure, connectivity and function across species. Each species, however, can adopt structural and/or functional retinal specializations, implementing variations to the basic design in order to satisfy unique requirements in visual function. Recent advances in molecular tools, imaging and electrophysiological approaches have greatly facilitated identification of the cellular and molecular mechanisms that establish the fundamental organization of the retina and the specializations of its microcircuits during development. Here, we review advances in our understanding of how these mechanisms act to shape structure and function at the single cell level, to coordinate the assembly of cell populations, and to define their specific circuitry. We also highlight how structure is rearranged and function is disrupted in disease, and discuss current approaches to re-establish the intricate functional architecture of the retina.

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Crossref · 10.1016/j.preteyeres.2014.06.003

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Metadata

Authors
Hoon, M., Okawa, H., Della Santina, L., & Wong, R. O. L.
Venue
Progress in Retinal and Eye Research
Publisher
Elsevier BV
Published
2014-09
Volume
42
Pages
44-84
ISSN
1350-9462 (ISSN-L)
OpenAlex
W1996609490
Cited by
585
References
429
FWCI
6.94
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Functional architecture of the retina: Development and disease. https://app.cochat.ai/papers/10.1016/j.preteyeres.2014.06.003
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Hoon, M., Okawa, H., Della Santina, L., & Wong, R. O. L. (2014). Functional architecture of the retina: Development and disease. Progress in Retinal and Eye Research. https://doi.org/10.1016/j.preteyeres.2014.06.003

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.