The DOI matches its Crossref record; 429 of the 429 references it cites were found in a registry or an index.
Functional architecture of the retina: Development and disease
Open accessAbstract
Structure and function are highly correlated in the vertebrate retina, a sensory tissue that is organized into cell layers with microcircuits working in parallel and together to encode visual information. All vertebrate retinas share a fundamental plan, comprising five major neuronal cell classes with cell body distributions and connectivity arranged in stereotypic patterns. Conserved features in retinal design have enabled detailed analysis and comparisons of structure, connectivity and function across species. Each species, however, can adopt structural and/or functional retinal specializations, implementing variations to the basic design in order to satisfy unique requirements in visual function. Recent advances in molecular tools, imaging and electrophysiological approaches have greatly facilitated identification of the cellular and molecular mechanisms that establish the fundamental organization of the retina and the specializations of its microcircuits during development. Here, we review advances in our understanding of how these mechanisms act to shape structure and function at the single cell level, to coordinate the assembly of cell populations, and to define their specific circuitry. We also highlight how structure is rearranged and function is disrupted in disease, and discuss current approaches to re-establish the intricate functional architecture of the retina.
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Cites
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Metadata
- Authors
- Hoon, M., Okawa, H., Della Santina, L., & Wong, R. O. L.
- Venue
- Progress in Retinal and Eye Research
- Publisher
- Elsevier BV
- Published
- 2014-09
- Volume
- 42
- Pages
- 44-84
- ISSN
- 1350-9462 (ISSN-L)
- OpenAlex
- W1996609490
- Cited by
- 585
- References
- 429
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- green
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- Hoon, M., Okawa, H., Della Santina, L., & Wong, R. O. L. (2014). Functional architecture of the retina: Development and disease. Progress in Retinal and Eye Research. https://doi.org/10.1016/j.preteyeres.2014.06.003
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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