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Cited by 543

The DOI matches its Crossref record; 65 of the 65 references it cites were found in a registry or an index.

Validity of the patient health questionnaire-9 for depression screening and diagnosis in East Africa

Open access
Gelaye, Bizu, Williams, Michelle A., Lemma, Seblewengel, Deyessa, Negussie, Bahretibeb, Yonas, Shibre, Teshome, Wondimagegn, Dawit, Lemenhe, Asnake, Fann, Jesse R., Vander Stoep, Ann, Andrew Zhou, Xiao-Hua·2013·Psychiatry Research

Abstract

Depression is often underdiagnosed and undertreated in primary care settings, particularly in developing countries. This is, in part, due to challenges resulting from a lack of skilled mental health workers, stigma associated with mental illness, and lack of cross-culturally validated screening instruments. We conducted this study to evaluate the reliability and validity of the Patient Health Questionnaire-9 (PHQ-9) questionnaire as a screen for diagnosing major depressive disorder among adults in Ethiopia, the second most populous country in sub-Saharan Africa. A total of 926 adults attending outpatient departments in a major referral hospital in Ethiopia participated in this study. We assessed criterion validity and performance characteristics against an independent, blinded, and psychiatrist administered semi-structured Schedules for Clinical Assessment in Neuropsychiatry (SCAN) interview. Overall, the PHQ-9 items showed good internal (Cronbach's alpha=0.85) and test re-test reliability (intraclass correlation coefficient=0.92). A factor analysis confirmed a 1-factor structure. Receiver Operating Characteristics (ROC) analysis showed that a PHQ-9 threshold score of 10 offered optimal discriminatory power with respect to diagnosis of MDD via the clinical interview (sensitivity=86% and specificity=67%). The PHQ-9 appears to be a reliable and valid instrument that may be used to diagnose major depressive disorders among Ethiopian adults.

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Metadata

Authors
Gelaye, B., Williams, M. A., Lemma, S., Deyessa, N., Bahretibeb, Y., Shibre, T., Wondimagegn, D., Lemenhe, A., Fann, J. R., Vander Stoep, A., & Andrew Zhou, X.-H.
Venue
Psychiatry Research
Publisher
Elsevier BV
Published
2013-12
Volume
210
Issue
2
Pages
653-661
ISSN
0165-1781 (ISSN-L)
OpenAlex
W2083334198
Cited by
543
References
65
FWCI
20.56
Type
journal article
Language
en
Open access
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CoChat. (2026). Citation check: Validity of the patient health questionnaire-9 for depression screening and diagnosis in East Africa. https://app.cochat.ai/papers/10.1016/j.psychres.2013.07.015
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Gelaye, B., Williams, M. A., Lemma, S., Deyessa, N., Bahretibeb, Y., Shibre, T., Wondimagegn, D., Lemenhe, A., Fann, J. R., Vander Stoep, A., & Andrew Zhou, X.-H. (2013). Validity of the patient health questionnaire-9 for depression screening and diagnosis in East Africa. Psychiatry Research. https://doi.org/10.1016/j.psychres.2013.07.015

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