The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Why avoid the hippocampus? A comprehensive review
Open accessAbstract
In this review article, we provide a detailed and comprehensive discussion of the rationale for using modern IMRT techniques to spare the subgranular zone of the hippocampus during cranial irradiation. We review the literature on neurocognitive effects of cranial irradiation; discuss clinical and preclinical data associating damage to neural progrenitor cells located in subgranular zone of the hippocampus with radiation-induced neurocognitive decline, specifically in terms of short-term memory formation and recall; and present a review of our pilot investigations into the feasibility and risks of sparing the subgranular zone of the hippocampus during whole-brain radiotherapy for brain metastases. We also introduce our phase II cooperative group clinical trial (RTOG 0933) designed to prospectively evaluate the postulated neurocognitive benefit of hippocampal subgranular zone sparing and scheduled to open in 2010.
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Cites
Kuhn, H., Dickinson-Anson, H., & Gage, F. (1996) · The Journal of Neuroscience · doi:10.1523/jneurosci.16-06-02027.1996 · Cited by 3,139
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
Monje, M. L., Toda, H., & Palmer, T. D. (2003) · Science · doi:10.1126/science.1088417 · Cited by 2,426
Gould, E., McEwen, B. S., Tanapat, P., Galea, L. A. M., & Fuchs, E. (1997) · The Journal of Neuroscience · doi:10.1523/jneurosci.17-07-02492.1997 · Cited by 1,496
Irradiation induces neural precursor-cell dysfunction
Monje, M. L., Mizumatsu, S., Fike, J. R., & Palmer, T. D. (2002) · Nature Medicine · doi:10.1038/nm749 · Cited by 1,271
Lemaire, V., Koehl, M., Le Moal, M., & Abrous, D. N. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.20.11032 · Cited by 1,044
Cited by
Yamamoto, M., Serizawa, T., Shuto, T., Akabane, A., Higuchi, Y., Kawagishi, J., Yamanaka, K., Sato, Y., Jokura, H., Yomo, S., et al. (2014) · The Lancet Oncology · doi:10.1016/s1470-2045(14)70061-0 · Cited by 1,447
Gondi, V., Hermann, B. P., Mehta, M. P., & Tomé, W. A. (2013) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2012.11.031 · Cited by 448
Self-citationZimmermann, S., Dziadziuszko, R., & Peters, S. (2014) · Cancer Treatment Reviews · doi:10.1016/j.ctrv.2014.03.005 · Cited by 147
Metadata
- Authors
- Gondi, V., Tomé, W. A., & Mehta, M. P.
- Venue
- Radiotherapy and Oncology
- Publisher
- Elsevier BV
- Published
- 2010-12
- Volume
- 97
- Issue
- 3
- Pages
- 370-376
- ISSN
- 0167-8140 (ISSN-L)
- OpenAlex
- W2002170698
- Cited by
- 398
- References
- 5
- FWCI
- 10.82
- Type
- journal article
- Language
- en
- Open access
- green
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- Gondi, V., Tomé, W. A., & Mehta, M. P. (2010). Why avoid the hippocampus? A comprehensive review. Radiotherapy and Oncology. https://doi.org/10.1016/j.radonc.2010.09.013
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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