Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission
Cited by (547)
Items 101–200 of 547
- RETRACTED: DUSP1 recuses diabetic nephropathy via repressing JNK‐Mff‐mitochondrial fission pathwaysJunqin Sheng, Hongyan Li, Qin Dai, Chang Lu, Min Xu, Jisheng Zhang, Jianxun Feng · 2018 · Journal of Cellular Physiology · Retracted
- Mitochondria in endothelial cells angiogenesis and function: current understanding and future perspectivesZhen Luo, Jianbo Yao, Zhe Wang, Jianxiong Xu · 2023 · Journal of Translational Medicine
- Nicorandil alleviates cardiac microvascular ferroptosis in diabetic cardiomyopathy: Role of the mitochondria-localized AMPK-Parkin-ACSL4 signaling pathwayZhangwei Chen, Li Su, Muyin Liu, Ming Yin, Jinxiang Chen, Youran Li, Qiyu Li, You Zhou, Yan Xia, Ao Chen et al. · 2024 · Pharmacological Research
- Mitochonic acid 5 activates the MAPK–ERK–yap signaling pathways to protect mouse microglial BV-2 cells against TNFα-induced apoptosis via increased Bnip3-related mitophagyQingyun Lei, Jian Tan, Shangqing Yi, Na Wu, Yilin Wang, Heng Wu · 2018 · Cellular & Molecular Biology Letters
- Inhibition of pyruvate dehydrogenase kinase 4 ameliorates kidney ischemia-reperfusion injury by reducing succinate accumulation during ischemia and preserving mitochondrial function during reperfusionChang Joo Oh, Min‐Ji Kim, Ji-Min Lee, Dong Hun Kim, Il‐Young Kim, Sanghee Park, Yeongmin Kim, Kyung‐Bok Lee, Sang‐Hee Lee, Chae Won Lim et al. · 2023 · Kidney International
- Therapeutic contribution of melatonin to the treatment of septic cardiomyopathy: A novel mechanism linking Ripk3-modified mitochondrial performance and endoplasmic reticulum functionJiankai Zhong, Ying Tan, Jianhua Lu, Jichen Liu, Xiaochan Xiao, Pinji Zhu, Sainan Chen, Sulin Zheng, Yuying Chen, Yunzhao Hu et al. · 2019 · Redox Biology
- Cardioprotective Role of Melatonin in Acute Myocardial InfarctionZhenhong Fu, Yang Jiao, Jihang Wang, Ying Zhang, Mingzhi Shen, Russel Joseph Reiter, Qing Xi, Yundai Chen · 2020 · Frontiers in Physiology
- Longevity genes, cardiac ageing, and the pathogenesis of cardiomyopathy: implications for understanding the effects of current and future treatments for heart failureMilton Packer · 2020 · European Heart Journal
- Empagliflozin restores chronic kidney disease–induced impairment of endothelial regulation of cardiomyocyte relaxation and contractionRio P. Juni, Rushd Al‐Shama, Diederik W.D. Kuster, Jolanda van der Velden, Henrike M. Hamer, Marc G. Vervloet, Etto C. Eringa, Pieter Koolwijk, Victor W.M. van Hinsbergh · 2020 · Kidney International
- The Pathophysiological Basis of Diabetic Cardiomyopathy DevelopmentАвагимян Ашот Арманович, Sergey Valentinovich Popov, Svetlana Anatolievna Shalnova · 2022 · Current Problems in Cardiology
- Heart failure with preserved ejection fraction (HFpEF) in type 2 diabetes mellitus: from pathophysiology to therapeuticsMiyesaier Abudureyimu, Xuanming Luo, Xiang Wang, James R. Sowers, Wenshuo Wang, Junbo Ge, Jun Tao Ren, Yingmei Zhang · 2022 · Journal of Molecular Cell Biology
- Collagen code in tumor microenvironment: Functions, molecular mechanisms, and therapeutic implicationsQian Zhang, Zi-Yi An, Wen G. Jiang, Weilin Jin, Xinyang He · 2023 · Biomedicine & Pharmacotherapy
- Mitochondrial superoxide/hydrogen peroxide: An emerging therapeutic target for metabolic diseasesJialong Yan, Jinyong Jiang, Lu He, Linxi Chen · 2020 · Free Radical Biology and Medicine
- A SGLT2 Inhibitor Dapagliflozin Alleviates Diabetic Cardiomyopathy by Suppressing High Glucose-Induced Oxidative Stress in vivo and in vitroYujie Xing, Biaohu Liu, Shujun Wan, Yi Min Cheng, Si-min Zhou, Yue Sun, Xin-ming Yao, Qiang Hua, Xiang-jian Meng, Jinhan Cheng et al. · 2021 · Frontiers in Pharmacology
- [Retracted] Irisin Attenuates Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in the H9C2 Cellular Model of Septic Cardiomyopathy through Augmenting Fundc1‐Dependent MitophagyXiaoqing Jiang, Shumin Cai, Yinghui Jin, Feng Wu, Jing He, Xixuan Wu, Ying Tan, Yu Wang · 2021 · Oxidative Medicine and Cellular Longevity · Retracted
- Chronic Empagliflozin Treatment Reduces Myocardial Infarct Size in Nondiabetic Mice Through STAT-3-Mediated Protection on Microvascular Endothelial Cells and Reduction of Oxidative StressPanagiota Nikolaou, Panagiotis Efentakis, Fairouz Abu Qourah, Saveria Femminò, Manousos Makridakis, Zoi Kanaki, Aimilia Varela, Maria E. Tsoumani, Constantinos H. Davos, Constantinos A. Dimitriou et al. · 2020 · Antioxidants and Redox Signaling
- Melatonin fine-tunes intracellular calcium signals and eliminates myocardial damage through the IP3R/MCU pathways in cardiorenal syndrome type 3Jin Wang, Sam Toan, Ruibing Li, Hao Zhou · 2020 · Biochemical Pharmacology
- Sodium Glucose Co-Transporter 2 Inhibitors Ameliorate Endothelium Barrier Dysfunction Induced by Cyclic Stretch through Inhibition of Reactive Oxygen SpeciesXiaoling Li, Gregor Römer, Raphaela P. Kerindongo, Jeroen Hermanides, Martin Albrecht, Markus Werner Hollmann, Coert Jozef Zuurbier, Benedikt Preckel, Nina Claudia Weber · 2021 · International Journal of Molecular Sciences
- Mitochondrial quality control in diabetic cardiomyopathy: from molecular mechanisms to therapeutic strategiesChen Cai, Feng Wu, Jing He, Yaoyuan Zhang, Nengxian Shi, Xiaojie Peng, Qing Ou, Ziying Li, Xiaoqing Jiang, Jiankai Zhong et al. · 2022 · International Journal of Biological Sciences
- Repurposing SGLT-2 Inhibitors to Target Aging: Available Evidence and Molecular MechanismsRosalba La Grotta, Chiara Frigé, Giulia Matacchione, Fabiola Olivieri, Paola de Candia, Antonio Ceriello, Francesco Prattichizzo · 2022 · International Journal of Molecular Sciences
- Energy metabolism disorders and potential therapeutic drugs in heart failureYanan He, Wei Huang, Chen Zhang, Lumeng Chen, Runchun Xu, Nan Li, Fang Wang, Li Han, Ming Yang, Dingkun Zhang · 2020 · Acta Pharmaceutica Sinica B
- PGAM5-Mediated PHB2 Dephosphorylation Contributes to Diabetic Cardiomyopathy by Disrupting Mitochondrial Quality SurveillanceRongjun Zou, Jun Tao, Jie He, Chaojie Wang, Songtao Tan, Yu Xia, Xing Chang, Ruibin Li, Ge Wang, Hao Zhou et al. · 2022 · Research
- NR4A1 contributes to high-fat associated endothelial dysfunction by promoting CaMKII-Parkin-mitophagy pathwaysPei Li, Yuzhi Bai, Xia Zhao, Tian Tian, Liying Tang, Jing Ru, Yun An, Jing Wang · 2018 · Cell Stress and Chaperones
- SGLT2 Inhibitors: A Novel Player in the Treatment and Prevention of Diabetic CardiomyopathyNa Li, Hong Zhou · 2020 · Drug Design Development and Therapy
- Cardiovascular Benefits from Gliflozins: Effects on Endothelial FunctionTeresa Salvatore, Alfredo Caturano, Raffaele Galiero, Anna Di Martino, Gaetana Albanese, Erica Vetrano, Celestino Sardu, Raffaele Marfella, Luca Rinaldi, Ferdinando Carlo Sasso · 2021 · Biomedicines
- Oxidative Stress, Inflammation, and Mitochondrial Dysfunction: A Link between Obesity and Atrial FibrillationAlkora Ioana Balan, Vasile-Bogdan Halațiu, Alina Scridon · 2024 · Antioxidants
- AMPK is associated with the beneficial effects of antidiabetic agents on cardiovascular diseasesLu, Qingguo, Li, Xuan, Liu, Jia, Sun, Xiaodong, Rousselle, Thomas, Ren, Di, Tong, Nanwei, Li, Ji · 2019 · Bioscience Reports
- Mitochondrial Fission as a Therapeutic Target for Metabolic Diseases: Insights into Antioxidant StrategiesTianzheng Yu, Li Wang, Lei Zhang, Patricia Anne Deuster · 2023 · Antioxidants
- Mst1 regulates post-infarction cardiac injury through the JNK-Drp1-mitochondrial fission pathwayXisong Wang, Qing Song · 2018 · Cellular & Molecular Biology Letters
- Sirt3 inhibits cerebral ischemia-reperfusion injury through normalizing Wnt/β-catenin pathway and blocking mitochondrial fissionHao Zhao, Yongchun Luo, Lihua Chen, Zhenhai Zhang, Chunsen Shen, Yunjun Li, Ruxiang Xu · 2018 · Cell Stress and Chaperones
- Mitochondrial dysfunction in diabetes and the regulatory roles of antidiabetic agents on the mitochondrial functionHabib Yaribeygi, Stephen Lawrence Atkin, Amirhossein Sahebkar · 2018 · Journal of Cellular Physiology
- Molecular, Cellular, and Clinical Evidence That Sodium‐Glucose Cotransporter 2 Inhibitors Act as Neurohormonal Antagonists When Used for the Treatment of Chronic Heart FailureMilton Packer · 2020 · Journal of the American Heart Association
- Resveratrol Improves Bnip3-Related Mitophagy and Attenuates High-Fat-Induced Endothelial DysfunctionChen Li, Ying Tan, Jiandi Wu, Qinghui Ma, Shu-chang Bai, Zhangqing Xia, Xiaoliang Wan, Jianqiu Liang · 2020 · Frontiers in Cell and Developmental Biology
- miR-125a induces apoptosis, metabolism disorder and migrationimpairment in pancreatic cancer cells by targeting Mfn2-related mitochondrial fissionLichao Pan, Lin Zhou, Weijia Yin, Jia Qi Adam Bai, Rong Liu · 2018 · International Journal of Oncology
- NR4A1 Promotes Diabetic Nephropathy by Activating Mff-Mediated Mitochondrial Fission and Suppressing Parkin-Mediated MitophagyJunqin Sheng, Hongyan Li, Qin Dai, Chang Lu, Min Xu, Jisheng Zhang, Jianxun Feng · 2018 · Cellular Physiology and Biochemistry
- Mechanisms and Therapeutic Prospects of Diabetic Cardiomyopathy Through the Inflammatory ResponseNamrita Kaur, Yingshu Guan, Rida Raja, Andrea Ruiz‐Velasco, Wei Liu · 2021 · Frontiers in Physiology
- Neutrophil-like cell membrane-coated siRNA of lncRNA AABR07017145.1 therapy for cardiac hypertrophy via inhibiting ferroptosis of CMECsPilong Shi, Minghui Li, Chao Song, Hanping Qi, Lina Ba, Yonggang Cao, Meitian Zhang, Yawen Xie, Jing Ren, Jiabi Wu et al. · 2021 · Molecular Therapy — Nucleic Acids
- Cardioprotection by selective SGLT-2 inhibitors in a non-diabetic mouse model of myocardial ischemia/reperfusion injury: a class or a drug effect?Panagiota Nikolaou, Nikolaos Mylonas, Manousos Makridakis, Marina Makrecka‐Kuka, Aikaterini Iliou, Stelios Zerikiotis, Panagiotis Efentakis, Stavros Kampoukos, Nikolaos G Kostomitsopoulos, Reinis Vilšķe̅rsts et al. · 2022 · Basic Research in Cardiology
- Mitochondrial dysfunction and oxidative stress in diabetic woundGuoyong Jiang, Tao Jiang, Jing Chen, Haibo Yao, Renqun Mao, Xiaofan Yang, Zhenbing Chen, Wenqing Li · 2023 · Journal of Biochemical and Molecular Toxicology
- Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new applicationAmir Mohamed Abdelhamid, Sameh Saber, Mahmoud E. Youssef, Ahmed Gaafar Ahmed Gaafar, Hanan Eissa, Marwa A. Abdel-Dayem, Mohammed Alqarni, Gaber El‐Saber Batiha, Ahmad J. Obaidullah, Mohamed Awad Shahien et al. · 2021 · Biomedicine & Pharmacotherapy
- Mechanistic insights of soluble uric acid-induced insulin resistance: Insulin signaling and beyondWei Yu, De Xie, Tetsuya Yamamoto, Hidenori Koyama, Jidong Cheng · 2023 · Reviews in Endocrine and Metabolic Disorders
- Empagliflozin suppresses mitochondrial reactive oxygen species generation and mitigates the inducibility of atrial fibrillation in diabetic ratsTakuya Koizumi, Masaya Watanabe, Takashi Yokota, Masumi Tsuda, Haruka Handa, Jiro Koya, Kotaro Nishino, Daishiro Tatsuta, Hiroyuki Natsui, Takahide Kadosaka et al. · 2023 · Frontiers in Cardiovascular Medicine
- SIRT3 Facilitates Amniotic Fluid Stem Cells to Repair Diabetic Nephropathy Through Protecting Mitochondrial Homeostasis by Modulation of MitophagyJianxun Feng, Chang Lu, Qin Dai, Junqin Sheng, Min Xu · 2018 · Cellular Physiology and Biochemistry
- PKM2 regulates angiogenesis of VR‐EPCs through modulating glycolysis, mitochondrial fission, and fusionRanyue Ren, Jiachao Guo, Jia Yu Shi, Yong Tian, Mengwei Li, Hao Kang · 2020 · Journal of Cellular Physiology
- Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative ColitisMahmoud E. Youssef, Eslam E. Abd El-Fattah, Amir M. Abdelhamid, Hanan Eissa, Eman G El-Ahwany, Noha A. Amin, Helal F. Hetta, Mohamed H. Mahmoud, Gaber El‐Saber Batiha, Naglaa A. Gobba et al. · 2021 · Frontiers in Pharmacology
- Mitochondrial Transfer in Cardiovascular Disease: From Mechanisms to Therapeutic ImplicationsJun Chen, Jinjie Zhong, Linlin Wang, Yingying Chen · 2021 · Frontiers in Cardiovascular Medicine
- Empagliflozin attenuates trastuzumab-induced cardiotoxicity through suppression of DNA damage and ferroptosisJie Min, Lin Wu, Yandong Liu, Guoliang Song, Qinqin Deng, Jin jia Wei, Wei Yu, Miyesaier Abudureyimu, Zhaohui Pei, Jun Tao Ren · 2022 · Life Sciences
- Dapagliflozin prevents oxidative stress-induced endothelial dysfunction via sirtuin 1 activationYing Zhou, Shi Tai, Ningjie Zhang, Liyao Fu, Yongjun Wang · 2023 · Biomedicine & Pharmacotherapy
- Chronic hyperglycemia and cardiovascular dysfunction: an in-depth exploration of metabolic and cellular pathways in type 2 diabetes mellitusAraiz Hussain · 2025 · Cardiovascular Diabetology – Endocrinology Reports
- Autophagy Dysregulation in Diabetic Kidney Disease: From Pathophysiology to Pharmacological InterventionsClaudio Daniel González, María Paula Carro Negueruela, Catalina Nicora Santamarina, Roxana Resnik, María I. Vaccaro · 2021 · Cells
- Empagliflozin improves renal ischemia–reperfusion injury by reducing inflammation and enhancing mitochondrial fusion through AMPK–OPA1 pathway promotionWenbo Yang, Xiaoli Li, Liujie He, Shuyang Zhu, Shicong Lai, Xiaopeng Zhang, Zixiong Huang, Biyue Yu, Chun‐Ping Cui, Qiang Wang · 2023 · Cellular & Molecular Biology Letters
- Caveolin‐1 knockdown increases the therapeutic sensitivity of lung cancer to cisplatin‐induced apoptosis by repressing Parkin‐related mitophagy and activating the ROCK1 pathwayYi Liu, Yili Fu, Xianoxing Hu, Shuo Chen, Jinbai Miao, Yang Wang, Ying Zhou, Yuan Zhang · 2019 · Journal of Cellular Physiology
- Endothelial function and dysfunction: Impact of sodium-glucose cotransporter 2 inhibitorsAzizah Ugusman, Jaya Kumar, Amilia Aminuddin · 2021 · Pharmacology & Therapeutics
- L‐carnitine alleviates cardiac microvascular dysfunction in diabetic cardiomyopathy by enhancing PINK1‐Parkin ‐dependent mitophagy through the CPT1a‐PHB2‐PARL pathwaysLi Su, Muyin Liu, Jinxiang Chen, Yuqiong Chen, Ming Yin, You Zhou, Qiyu Li, Fei Xu, Youran Li, Xiaopei Yan et al. · 2023 · Acta Physiologica
- TRPV4-mediated mitochondrial dysfunction induces pyroptosis and cartilage degradation in osteoarthritis via the Drp1-HK2 axisZijian Yan, Zili He, Hongyi Jiang, Yu Zhang, Yitie Xu, Yingze Zhang · 2023 · International Immunopharmacology
- Loss of AKAP1 triggers Drp1 dephosphorylation-mediated mitochondrial fission and loss in retinal ganglion cellsGenea Edwards, Guy A Perkins, Keun-young Kim A, YeEun Kong, Yonghoon Lee, Soo‐Ho Choi, Yujia Liu, Dorota Skowronska‐Krawczyk, Robert Neal Weinreb, Linda M. Zangwill et al. · 2020 · Cell Death and Disease
- Diabetes pathogenesis and management: the endothelium comes of ageKaitlin M. Love, Eugene J. Barrett, Steven K. Malin, Jane E.B. Reusch, Judith G. Regensteiner, Zhenqi Liu · 2021 · Journal of Molecular Cell Biology
- Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fissionYanqing Wang, Qian Liu, Jiaying Cai, Wu Pin, Di Wang, Yundi Shi, Tianru Huyan, Jing Su, Xuejun Li, Qi Wang et al. · 2021 · European Journal of Pharmacology
- Mst1 deletion attenuates renal ischaemia-reperfusion injury: The role of microtubule cytoskeleton dynamics, mitochondrial fission and the GSK3β-p53 signalling pathwayHongyan Li, Jianxun Feng, Yunfang Zhang, Junxia Feng, Qi Wang, Shili Zhao, Ping Meng, Jingchun Li · 2018 · Redox Biology
- Acrolein Aggravates Secondary Brain Injury After Intracerebral Hemorrhage Through Drp1-Mediated Mitochondrial Oxidative Damage in MiceXun Wu, Wenxing Cui, Wei Guo, Haixiao Liu, Jianing Luo, Lei Zhao, Hao Guo, Longlong Zheng, Hao Bai, Dayun Feng et al. · 2020 · Neuroscience Bulletin
- Research advances in the anti-inflammatory effects of SGLT inhibitors in type 2 diabetes mellitusRuining Zhang, Qingxing Xie, Xi Lu, Rongping Fan, Nanwei Tong · 2024 · Diabetology & Metabolic Syndrome
- Mitochondrial network remodeling of the diabetic heart: implications to ischemia related cardiac dysfunctionMichael W. Rudokas, Margaret McKay, Zeren Toksoy, Julia N. Eisen, Markus Bögner, Lawrence H. Young, Fadi G. Akar · 2024 · Cardiovascular Diabetology
- Empagliflozin mitigates type 2 diabetes-associated peripheral neuropathy: a glucose-independent effect through AMPK signalingNoha F. Abdelkader, Marawan A. Elbaset, Passant E. Moustafa, Sherehan M. Ibrahim · 2022 · Archives of Pharmacal Research
- SGLT2 inhibitor ameliorates endothelial dysfunction associated with the commonALDH2alcohol flushing variantHongchao Guo, Xuan Yu, Yu Liu, David T. Paik, Johanne Marie Justesen, Mark Chandy, James W.S. Jahng, Tiejun Zhang, Weijun Wu, Freeborn Rwere et al. · 2023 · Science Translational Medicine
- Vascular (dys)function in the failing heartLuca Liberale, Dirk Jan Duncker, Derek John Hausenloy, Simon C Kraler, Hans Erik Bøtker, Bruno Karl Podesser, Gerd Heusch, Petra Kleinbongard · 2025 · Nature Reviews Cardiology
- RETRACTED: Tanshinone IIA promotes IL2-mediated SW480 colorectal cancer cell apoptosis by triggering INF2-related mitochondrial fission and activating the Mst1-Hippo pathwayJun Qian, Dong Fang, Hong Lu, Yi Lin Cao, Ji Zhang, Rong Ding, Lingchang Li, Jiege Huo · 2018 · Biomedicine & Pharmacotherapy · Retracted
- Melatonin Attenuates Cardiac Reperfusion Stress by Improving OPA1-Related Mitochondrial Fusion in a Yap–Hippo Pathway–Dependent MannerShuxian Ma, Zhenming Dong · 2018 · Journal of Cardiovascular Pharmacology
- Brain-derived neurotrophic factor mimetic, 7,8-dihydroxyflavone, protects against myocardial ischemia by rebalancing optic atrophy 1 processingZhen Wang, Shi-Peng Wang, Qun Shao, Peifeng Li, Yue Sun, Lan-Zi Luo, Xiuqing Yan, Ziyi Fan, Juan Hu, Jing Zhao et al. · 2019 · Free Radical Biology and Medicine
- Combination of melatonin and irisin ameliorates lipopolysaccharide‐induced cardiac dysfunction through suppressing the Mst1–JNK pathwaysHaichun Ouyang, Qian Li, Jiankai Zhong, Fengfan Xia, Sulin Zheng, Jianhua Lu, Yuanyan Deng, Yunzhao Hu · 2020 · Journal of Cellular Physiology
- RIPK3 Induces Cardiomyocyte Necroptosis via Inhibition of AMPK‐Parkin‐Mitophagy in Cardiac Remodelling after Myocardial InfarctionPingjun Zhu, Kun Wan, Ming Yin, Peng Hu, Yifan Que, Xin Jin Zhou, Lei Zhang, Tianzhi Li, Yingzhen Du, Guogang Xu et al. · 2021 · Oxidative Medicine and Cellular Longevity
- Endothelial Protection by Sodium-Glucose Cotransporter 2 Inhibitors: A Literature Review of In Vitro and In Vivo StudiesNikolaos Mylonas, Panagiota Nikolaou, Paschalis Karakasis, Panagiotis Stachteas, Nikolaos Fragakis, Ioanna Andreadou · 2024 · International Journal of Molecular Sciences
- Mitochondrial Dysfunction and Diabetes: Is Mitochondrial Transfer a Friend or Foe?Magdalene K. Montgomery · 2019 · Biology
- Reinterpreting Cardiorenal Protection of Renal Sodium–Glucose Cotransporter 2 Inhibitors via Cellular Life History ProgrammingAngelo Avogaro, Gian Paolo Fadini, Stefano Del Prato · 2019 · Diabetes Care
- A complete review of empagliflozin: Most specific and potent SGLT2 inhibitor used for the treatment of type 2 diabetes mellitusGita Chawla, Krishna Kr. Chaudhary · 2019 · Diabetes & Metabolic Syndrome Clinical Research & Reviews
- Amelioration of endothelial dysfunction by sodium glucose co‐transporter 2 inhibitors: pieces of the puzzle explaining their cardiovascular protectionXiaoling Li, Benedikt Preckel, Jeroen Hermanides, Markus Werner Hollmann, Coert Jozef Zuurbier, Nina Claudia Weber · 2022 · British Journal of Pharmacology
- Mitochondrial quality control in cardiac fibrosis: Epigenetic mechanisms and therapeutic strategiesLi-Chan Lin, Bin Tu, Kai Song, Zhiyan Liu, He Sun, Yang Zhou, Ji-Ming Sha, Jingjing Yang, Zhang Ye, Jian‐Yuan Zhao et al. · 2023 · Metabolism
- Endothelial MICU1 alleviates diabetic cardiomyopathy by attenuating nitrative stress-mediated cardiac microvascular injuryXide Shi, Chao Liu, Jiangwei Chen, Shiqiang Zhou, Yajuan Li, Xingcheng Zhao, Jinliang Xing, Junhui Xue, Fengzhou Liu, Fei Li · 2023 · Cardiovascular Diabetology
- Tanshinone IIA attenuates cardiac microvascular ischemia-reperfusion injury via regulating the SIRT1-PGC1α-mitochondrial apoptosis pathwayJiankai Zhong, Haichun Ouyang, Mingming Sun, Jianhua Lu, Yuanlin Zhong, Ying Tan, Yunzhao Hu · 2019 · Cell Stress and Chaperones
- Clusterin ameliorates endothelial dysfunction in diabetes by suppressing mitochondrial fragmentationRen, Lulu, Han, Feifei, Xuan, Lingling, Lv, Yali, Gong, Lili, Yan, Yan, Wan, Zirui, Guo, Lifang, Liu, He, Xu, Benshan et al. · 2019 · Free Radical Biology and Medicine
- Mitochondria-Mediated Cardiovascular Benefits of Sodium-Glucose Co-Transporter 2 InhibitorsSiarhei A. Dabravolski, Alexander D. Zhuravlev, Andrey G. Kartuesov, Evgeny E. Borisov, Vasily N. Sukhorukov, Alexander Nikolaevich Orekhov · 2022 · International Journal of Molecular Sciences
- Direct Cardiac Actions of Sodium-Glucose Cotransporter 2 Inhibition Improve Mitochondrial Function and Attenuate Oxidative Stress in Pressure Overload-Induced Heart FailureXuan Li, Elizabeth R. Flynn, Jussara Marcia do Carmo, Zhen Wang, Alexandre A. da Silva, Alan J. Mouton, Ana Carolina Mieko Omoto, Michael E. Hall, John Edward Hall · 2022 · Frontiers in Cardiovascular Medicine
- RETRACTED: Therapeutic effects of melatonin on cerebral ischemia reperfusion injury: Role of Yap-OPA1 signaling pathway and mitochondrial fusionNa Wei, Yuehua Pu, Zhonghua Yang, Yuesong Pan, Liping Liu · 2018 · Biomedicine & Pharmacotherapy · Retracted
- Combined treatment with DPP-4 inhibitor linagliptin and SGLT2 inhibitor empagliflozin attenuates neointima formation after vascular injury in diabetic miceHiroyuki Takahashi, Takashi Nomiyama, Yuichi Terawaki, Takeshi Horikawa, Takako Kawanami, Yuriko Hamaguchi, Tomoko Tanaka, Ryoko Motonaga, Takashi Fukuda, Makito Tanabe et al. · 2019 · Biochemistry and Biophysics Reports
- Impact of Sodium–Glucose Cotransporter 2 (SGLT2) Inhibitors on Arterial Stiffness and Vascular Aging—What Do We Know So Far? (A Narrative Review)Cristina Andreea Adam, Razvan Constantin Anghel, Dragoș Traian Marius Marcu, Ovidiu Mitu, Mihai Roca, Florin Mitu · 2022 · Life
- Effects of the sodium-glucose cotransporter 2 inhibitor dapagliflozin on substrate metabolism in prediabetic insulin resistant individuals: A randomized, double-blind crossover trialAnna Veelen, Charlotte Andriessen, Yvo J.M. Op den Kamp, Edmundo Erazo‐Tapia, Marlies de Ligt, Julian Mevenkamp, Johanna A. Jörgensen, Esther Moonen‐Kornips, Gert Schaart, RUSSELL L. ESTERLINE et al. · 2022 · Metabolism
- Mitochondria-derived methylmalonic acid aggravates ischemia–reperfusion injury by activating reactive oxygen species-dependent ferroptosisJunchen Guo, Shanjie Wang, Xin Hua Wan, Xiaoxuan Liu, Zeng Wang, Chenchen Liang, Zhenming Zhang, Ye Wang, Miao Yan, Pengyan Wu et al. · 2024 · Cell Communication and Signaling
- Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolismYing Tan, Yue Zhang, Jing He, Feng Wu, Di Wu, Nengxian Shi, Weifeng Liu, Ziying Li, Wenqian Liu, Hao Zhou et al. · 2022 · Molecular Metabolism
- The dynamic interplay between cardiac mitochondrial health and myocardial structural remodeling in metabolic heart disease, aging, and heart failureBenjamin Werbner, Omid Mohammad Tavakoli‐Rouzbehani, Amir Nima Fatahian, Sihem Boudina · 2023 · The Journal of Cardiovascular Aging
- The effect of SGLT2 inhibitors on the endothelium and the microcirculation: from bench to bedside and beyondKyriakos S. Dimitriadis, Eleni Adamopoulou, Nikolaos Pyrpyris, Athanasios Sakalidis, Ioannis Leontsinis, Eleni Manta, Emmanouil Mantzouranis, Eirini Beneki, Στέργιος Σουλαϊδόπουλος, D. Konstantinidis et al. · 2023 · European Heart Journal - Cardiovascular Pharmacotherapy
- RETRACTED: LATS2 promotes apoptosis in non-small cell lung cancer A549 cells via triggering Mff-dependent mitochondrial fission and activating the JNK signaling pathwayYudong Xie, Yanping Lv, Yanli Zhang, Zhenzhen Liang, Lili Han, Yiyang Xie · 2018 · Biomedicine & Pharmacotherapy · Retracted
- Sepsis-related myocardial injury is associated with Mst1 upregulation, mitochondrial dysfunction and the Drp1/F-actin signaling pathwayXiuling Shang, Jun Li, Rongguo Yu, Pengli Zhu, Yingrui Zhang, Jingqing Xu, Kaihua Chen, Min Li · 2019 · Journal of Molecular Histology
- Empagliflozin prevents from early cardiac injury post myocardial infarction in non-diabetic miceYihai Liu, Mingyue Wu, Jiamin Xu, Biao Xu, Lina Kang · 2021 · European Journal of Pharmaceutical Sciences
- Empagliflozin attenuates doxorubicin-induced cardiotoxicity by activating AMPK/SIRT-1/PGC-1α-mediated mitochondrial biogenesisMeicong Chen · 2023 · Toxicology Research
- Sodium-Glucose Cotransporter 2 Inhibitors Potentially Prevent Atrial Fibrillation by Ameliorating Ion Handling and Mitochondrial DysfunctionXiaodong Peng, Linling Li, Mengxia Zhang, Qianqian Zhao, Kui Wu, Rong Bai, Yanfei Ruan, Nian Liu · 2020 · Frontiers in Physiology
- The role and mechanisms of microvascular damage in the ischemic myocardiumBang-Hao Zhao, Amanguli Ruze, Ling Zhao, Qiulin Li, Jing Yan Tang, Nilupaer Xiefukaiti, Min-Tao Gai, An-Xia Deng, Xue-Feng Shan, Xiao-Ming Gao · 2023 · Cellular and Molecular Life Sciences
- Mitochondrial quality control in diabetes mellitus and complications: molecular mechanisms and therapeutic strategiesYanling Chen, Xun Liu, Yixuan Liu, Yujia Li, Dingxiang Li, Zhigang Mei, Yihui Deng · 2025 · Cell Death and Disease
- SGLT2 inhibitors: a focus on cardiac benefits and potential mechanismsMaja D. Muric, Vladimir I. Zivkovic, Jovana Joksimović, Jasmina Z. Sretenovic, Goran Davidović, Stefan M. Simovic, Danijela Djoković, Nemanja N. Muric, Sergey Bolevich, Vladimir Lj. Jakovljevic · 2021 · Heart Failure Reviews
- RETRACTED: Oxidized LDL Causes Endothelial Apoptosis by Inhibiting Mitochondrial Fusion and Mitochondria AutophagyJia Zheng, Chengzhi Lu · 2020 · Frontiers in Cell and Developmental Biology · Retracted
- Empagliflozin-Enhanced Antioxidant Defense Attenuates Lipotoxicity and Protects Hepatocytes by Promoting FoxO3a- and Nrf2-Mediated Nuclear Translocation via the CAMKK2/AMPK PathwayYangyang Wang, Yipei Ding, Pengbo Sun, Wanqiu Zhang, Qilei Xin, Ningchao Wang, Yaoyun Niu, Yang Chen, Jingyi Luo, Jinghua Lu et al. · 2022 · Antioxidants
- Mitochondrial Dysfunction in Atrial Fibrillation—Mechanisms and Pharmacological InterventionsPaweł Muszyński, Tomasz Andrzej Bonda · 2021 · Journal of Clinical Medicine