Ren, Jun

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 3,996

Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases

Ren, J., Bi, Y., Sowers, J. R., Hetz, C., & Zhang, Y. (2021) · Nature Reviews Cardiology

Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research

Cited by 708

Empagliflozin rescues diabetic myocardial microvascular injury via AMPK-mediated inhibition of mitochondrial fission

Zhou, H., Wang, S., Zhu, P., Hu, S., Chen, Y., & Ren, J. (2018) · Redox Biology

Diabetes Treatment and ManagementCardiovascular Function and Risk Factors

Cited by 550

Targeting autophagy in obesity: from pathophysiology to management

Zhang, Y., Sowers, J. R., & Ren, J. (2018) · Nature Reviews Endocrinology

Autophagy in Disease and TherapyAdipokines, Inflammation, and Metabolic Diseases

Cited by 338

Leptin and hyperleptinemia - from friend to foe for cardiovascular function

Ren, J. (2004) · Journal of Endocrinology

Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic Diseases

Cited by 305

ER stress and UPR in Alzheimer’s disease: mechanisms, pathogenesis, treatments

Ajoolabady, A., Lindholm, D., Ren, J., & Pratico, D. (2022) · Cell Death & Disease

Endoplasmic Reticulum Stress and DiseaseAlzheimer's disease research and treatments

Cited by 261

Cardiac contractile dysfunction in Lep/Lep obesity is accompanied by NADPH oxidase activation, oxidative modification of sarco(endo)plasmic reticulum Ca2+-ATPase and myosin heavy chain isozyme switch

Li, S.-Y., Yang, X., Ceylan-Isik, A. F., Du, M., Sreejayan, N., & Ren, J. (2006) · Diabetologia

Cardiovascular Function and Risk FactorsCardiac electrophysiology and arrhythmias

Cited by 187

Metallothionein Prevents Diabetes-Induced Deficits in Cardiomyocytes by Inhibiting Reactive Oxygen Species Production

Ye, G., Metreveli, N. S., Ren, J., & Epstein, P. N. (2003) · Diabetes

Cardiovascular Function and Risk FactorsCardiac Ischemia and Reperfusion

Cited by 180

Glucagon-Like Peptide-1 Protects Against Cardiac Microvascular Injury in Diabetes via a cAMP/PKA/Rho-Dependent Mechanism

Wang, D., Luo, P., Wang, Y., Li, W., Wang, C., Sun, D., Zhang, R., Su, T., Ma, X., Zeng, C., et al. (2013) · Diabetes

Diabetes Treatment and ManagementCardiovascular Function and Risk Factors

Cited by 179

Impaired macrophage migration inhibitory factor-AMP-activated protein kinase activation and ischemic recovery in the senescent heart

Ma, H., Wang, J., Thomas, D. P., Tong, C., Leng, L., Wang, W., Merk, M., Zierow, S., Bernhagen, J., Ren, J., et al. (2010) · Circulation

Cardiac Ischemia and ReperfusionMacrophage Migration Inhibitory Factor

Cited by 164

Impaired cardiac contractile function in ventricular myocytes from leptin-deficient ob/ob obese mice

Dong, F., Zhang, X., Yang, X., Esberg, L. B., Yang, H., Zhang, Z., Culver, B., & Ren, J. (2006) · Journal of Endocrinology

Cardiovascular Function and Risk FactorsCardiac electrophysiology and arrhythmias

Cited by 155

High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis

Relling, D. P., Esberg, L. B., Fang, C. X., Johnson, W. T., Murphy, E. J., Carlson, E. C., Saari, J. T., & Ren, J. (2006) · Journal of Hypertension

Cardiovascular Function and Risk FactorsCardiac electrophysiology and arrhythmias

Cited by 151

AMP-activated protein kinase deficiency exacerbates aging-induced myocardial contractile dysfunction

Turdi, S., Fan, X., Li, J., Zhao, J., Huff, A. F., Du, M., & Ren, J. (2010) · Aging Cell

Metabolism, Diabetes, and CancerMitochondrial Function and Pathology

Cited by 141

ALDH2 contributes to melatonin-induced protection against APP/PS1 mutation-prompted cardiac anomalies through cGAS-STING-TBK1-mediated regulation of mitophagy

Wang, S., Wang, L., Qin, X., Turdi, S., Sun, D., Culver, B., Reiter, R. J., Wang, X., Zhou, H., & Ren, J. (2020) · Signal Transduction and Targeted Therapy

Alzheimer's disease research and treatmentsCircadian rhythm and melatonin

Cited by 135

Deficiency in AMP-activated protein kinase exaggerates high fat diet-induced cardiac hypertrophy and contractile dysfunction

Turdi, S., Kandadi, M. R., Zhao, J., Huff, A. F., Du, M., & Ren, J. (2011) · Journal of Molecular and Cellular Cardiology

Cardiovascular Function and Risk FactorsMetabolism, Diabetes, and Cancer

Cited by 103

Developmental Abnormalities of Neuronal Structure and Function in Prenatal Mice Lacking the Prader-Willi Syndrome Gene Necdin

Pagliardini, S., Ren, J., Wevrick, R., & Greer, J. J. (2005) · The American Journal of Pathology

Neuroscience of respiration and sleepGenetic Syndromes and Imprinting

Cited by 99

Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes

Li, S.-Y., Sigmon, V. K., Babcock, S. A., & Ren, J. (2007) · Life Sciences

Advanced Glycation End Products researchGlycosylation and Glycoproteins Research

Cited by 97

High‐fat diet enhances visceral advanced glycation end products, nuclear O‐Glc‐Nac modification, p38 mitogen‐activated protein kinase activation and apoptosis

Li, S. ‐., Liu, Y., Sigmon, V. K., McCort, A., & Ren, J. (2005) · Diabetes, Obesity and Metabolism

Advanced Glycation End Products researchDiet, Metabolism, and Disease

Cited by 95

Interaction between maternal and postnatal high fat diet leads to a greater risk of myocardial dysfunction in offspring via enhanced lipotoxicity, IRS-1 serine phosphorylation and mitochondrial defects

Turdi, S., Ge, W., Hu, N., Bradley, K. M., Wang, X., & Ren, J. (2013) · Journal of Molecular and Cellular Cardiology

Birth, Development, and HealthCardiovascular Function and Risk Factors

Cited by 88

Insulin resistance induces hyperleptinemia, cardiac contractile dysfunction but not cardiac leptin resistance in ventricular myocytes

Hintz, K. K., Aberle, N. S., & Ren, J. (2003) · International Journal of Obesity

Cardiovascular Function and Risk FactorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 64

PCSK9 in metabolism and diseases

Ajoolabady, A., Pratico, D., Mazidi, M., Davies, I. G., Lip, G. Y. H., Seidah, N., Libby, P., Kroemer, G., & Ren, J. (2025) · Metabolism

Lipoproteins and Cardiovascular HealthCholesterol and Lipid Metabolism

Cited by 49

Folic acid reverses nitric oxide synthase uncoupling and prevents cardiac dysfunction in insulin resistance: Role of Ca2+/calmodulin-activated protein kinase II

Roe, N. D., He, E. Y., Wu, Z., & Ren, J. (2013) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsCardiovascular Function and Risk Factors

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