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Higher BMI is associated with worse asthma control and quality of life but not asthma severity
Open accessAbstract
Asthma and obesity tend to co-occur, but relatively few studies have linked obesity, measured using body mass index (BMI), to clinically relevant measures of asthma morbidity. This study assessed BMI in a Canadian sample of asthma outpatients, and evaluated associations between BMI and levels of asthma severity, asthma control, and asthma-related quality of life. A total of 382 adult asthma patients underwent demographic and medical history interviews on the day of their clinic visit. Patients' self-reported height and weight were used to calculate BMI (kg/m(2)). Asthma severity was classified according the GINA (2002) guidelines. Patients completed the Asthma Control (ACQ) and Asthma Quality of Life (AQLQ) Questionnaires and underwent standard pulmonary testing (spirometry). A total of 139 (36%) patients had a normal BMI; 149 (39%) patients were overweight; and 94 (25%) patients were obese. There was no relationship between BMI and asthma severity when controlling for age and sex. Patients with higher BMI scores had higher ACQ and lower AQLQ scores, independent of age, sex and asthma severity. Results identify higher BMI and obesity as potential behavioral factors related to worse asthma control and quality of life, but not asthma severity, and suggest important avenues for asthma management and control initiatives.
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“For instance, a higher proportion of people with asthma seem to have overweight or obese BMI67 and weight loss intervention studies have been associated with improvements in asthma symptoms.68”
From A systematic review of psychological, physical health factors, and quality of life in adult asthma (2019) · cites this paper as [67]
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MethodResultInfluentialMultiple manifestations of uncontrolled asthma increase the risk of severe COVID-19
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Factors associated with health‐related quality of life among low‐compliant asthmatic adults in Korea
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“(8) might be due to the self-reported weight and height.”
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BackgroundManagement of Chronic Asthma in Adults
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BackgroundAssociation of Body Mass Index with Asthma Severity and Pulmonary Function among Asthmatic Children
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“, no significant relationship was obtained between asthma severity and BMI, but according to their findings, increase in BMI leads to difficulty of disease control (9).”
BackgroundAppropriate selection for omalizumab treatment in patients with severe asthma?
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MethodSelf-citationAtopic Dermatitis: Update on Pathogenesis and Comorbidities
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“reported that asthma control becomes poorer as BMI increases [99] .”
BackgroundObesity and asthma control in an urban population
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Background2018 International Behavioural Trials Network (IBTN) Conference Abstracts
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Association of body mass index with airway hyperresponsiveness and lung function in adult asthmatics
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“asthma and obesity report more asthma symptoms, show a reduced quality of life, a reduced response to medication, and poorer asthma control than patients who do not have obesity (9-11).”
BackgroundObesity and Lung Health in Children
Lang, J. E., & Bhammar, D. M. (2024) · Respiratory medicine · doi:10.1007/978-3-031-52696-1_16 · Cited by 3
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Metadata
- Authors
- Lavoie, K. L., Bacon, S. L., Labrecque, M., Cartier, A., & Ditto, B.
- Affiliations
- Université du Québec à Montréal (CA)
- Hôpital du Sacré-Cœur de Montréal (CA)
- McGill University (CA)
- Corresponding author
- Lavoie, Kim L.
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2006-04
- Volume
- 100
- Issue
- 4
- Pages
- 648-657
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W2058669590
- Cited by
- 243
- References
- 50
- Citations by year
- 2026: 4 · 2025: 8 · 2024: 7 · 2023: 8 · 2022: 9 · 2021: 8 · 2020: 12 · 2019: 8 · 2018: 12 · 2017: 13 · 2016: 8 · 2015: 11 · 2014: 20 · 2013: 19 · 2012: 21
- FWCI
- 6.02
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Canadian Institutes of Health Research
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Asthma and respiratory diseases
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- asthma, obesity, body mass index, asthma control, asthma quality of life, asthma severity, overweight, Asthma Control Questionnaire, Asthma Quality of Life Questionnaire
- MeSH terms
- Adult, Aged, Asthma, Bronchodilator Agents, Canada, Cross-Sectional Studies, Female, Forced Expiratory Volume, Humans, Male, Middle Aged, Obesity, Quality of Life, Surveys and Questionnaires, Severity of Illness Index, Comorbidity, Body Mass Index
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