The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
The incidence of cancer in patients with idiopathic pulmonary fibrosis and sarcoidosis in the UK
Open accessAbstract
BACKGROUND The aim of this study was to use a longitudinal computerised health care dataset (The Health Improvement Network) to provide information on the overall incidence of cancer, and on the incidence of organ-specific cancers, in people with idiopathic pulmonary fibrosis (IPF) and sarcoidosis in comparison to the general population. METHODS Incident cases of IPF and sarcoidosis were identified with up to four controls matched by age, gender and general practice. Cancer incidence rates were compared between cohorts using Cox regression and adjusting for age, gender and smoking habit. RESULTS One thousand and sixty-four incident cases of IPF (mean age at diagnosis 71.5 years; 62.4% male) were identified. Overall, the incidence of cancer was increased in people with IPF compared to the general population (rate ratio 1.51; 95% CI 1.20-1.90), but this was largely due to a marked increase in the incidence of lung cancer (rate ratio 4.96; 95% CI 3.00-8.18). One thousand one hundred and fifty-three incident cases of sarcoidosis (mean age at diagnosis 47.0 years; 47.2% male) were identified. There was an overall increased incidence of cancer in sarcoidosis (rate ratio 1.65; 95% CI 1.22-2.24) and this was largely explained by an increase in the incidence of skin cancers (rate ratio 1.86; 95% CI 1.11-3.11). CONCLUSIONS This study provides further evidence of a marked increase in the incidence of lung cancer in people with IPF, but we found no increase in the risk of other cancers. People with sarcoidosis did have an increase risk of skin cancers, but not cancers at other sites.
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Cites
Clinical Characteristics of Patients in a Case Control Study of Sarcoidosis
BAUGHMAN, R. P., TEIRSTEIN, A. S., JUDSON, M. A., ROSSMAN, M. D., YEAGER, H., BRESNITZ, E. A., DePALO, L., HUNNINGHAKE, G., IANNUZZI, M. C., JOHNS, C. J., et al. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.10.2104046 · Cited by 1,808
Cigarette smoking: a risk factor for idiopathic pulmonary fibrosis.
Baumgartner, K. B., Samet, J. M., Stidley, C. A., Colby, T. V., & Waldron, J. A. (1997) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.155.1.9001319 · Cited by 767
Lung Cancer and Cryptogenic Fibrosing Alveolitis: A Population-based Cohort Study
HUBBARD, R., VENN, A., LEWIS, S., & BRITTON, J. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.161.1.9906062 · Cited by 639
Self-citationThe UK General Practice Research Database
Walley, T., & Mantgani, A. (1997) · The Lancet · doi:10.1016/s0140-6736(97)04248-7 · Cited by 623
Cryptogenic fibrosing alveolitis and lung cancer.
Turner-Warwick, M., Lebowitz, M., Burrows, B., & Johnson, A. (1980) · Thorax · doi:10.1136/thx.35.7.496 · Cited by 349
The General Practice Research Database: Role in Pharmacovigilance
Wood, L., & Martinez, C. (2004) · Drug Safety · doi:10.2165/00002018-200427120-00004 · Cited by 331
Occupational exposure to metal or wood dust and aetiology of cryptogenic fibrosing alveolitis
Hubbard, R., Lewis, S., Richards, K., Johnston, I., & Britton, J. (1996) · The Lancet · doi:10.1016/s0140-6736(96)90465-1 · Cited by 318
Self-citationFeasibility study and methodology to create a quality-evaluated database of primary care data
Bourke, A., Dattani, H., & Robinson, M. (2004) · Journal of Innovation in Health Informatics · doi:10.14236/jhi.v12i3.124 · Cited by 285
Increased Risk for Cancer Following Sarcoidosis
ASKLING, J., GRUNEWALD, J., EKLUND, A., HILLERDAL, G., & EKBOM, A. (1999) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.160.5.9904045 · Cited by 260
The prognosis of cryptogenic fibrosing alveolitis
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Cited by
Lederer, D. J., & Martinez, F. J. (2018) · New England Journal of Medicine · doi:10.1056/nejmra1705751 · Cited by 2,056
Idiopathic pulmonary fibrosis: pathogenesis and management
Sgalla, G., Iovene, B., Calvello, M., Ori, M., Varone, F., & Richeldi, L. (2018) · Respiratory Research · doi:10.1186/s12931-018-0730-2 · Cited by 573
Lung Cancer in Never Smokers: Clinical Epidemiology and Environmental Risk Factors
Samet, J. M., Avila-Tang, E., Boffetta, P., Hannan, L. M., Olivo-Marston, S., Thun, M. J., & Rudin, C. M. (2009) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-09-0376 · Cited by 566
Cumulative incidence of and predictive factors for lung cancer in IPF
OZAWA, Y., SUDA, T., NAITO, T., ENOMOTO, N., HASHIMOTO, D., FUJISAWA, T., NAKAMURA, Y., INUI, N., NAKAMURA, H., & CHIDA, K. (2009) · Respirology · doi:10.1111/j.1440-1843.2009.01547.x · Cited by 314
Idiopathic Pulmonary Fibrosis and Lung Cancer: Mechanisms and Molecular Targets
Ballester, B., Milara, J., & Cortijo, J. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20030593 · Cited by 308
Metadata
- Authors
- Le Jeune, I., Gribbin, J., West, J., Smith, C., Cullinan, P., & Hubbard, R.
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2007-12
- Volume
- 101
- Issue
- 12
- Pages
- 2534-2540
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W1988781537
- Cited by
- 296
- References
- 12
- FWCI
- 8.33
- Type
- journal article
- Language
- en
- Open access
- bronze
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