The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
Adherence to COPD treatment: Myth and reality
Open accessAbstract
COPD is a chronic disease in which effective management requires long-term adherence to pharmacotherapies but the level of adhesion to the prescribed medications is very low and this has a negative influence on outcomes. There are several approaches to detect non-adherence, such as pharmacy refill methods, electronic monitoring, and self-report measures, but they are all burdened with important limitations. Medication adherence in COPD is multifactorial and is affected by patients (health beliefs, cognitive abilities, self-efficacy, comorbidities, psychological profile, conscientiousness), physicians (method of administration, dosing regimen, polypharmacy, side effects), and society (patient-prescriber relationship, social support, access to medication, device training, follow-up). Patient-health care professional communication, especially that between patient and physician or pharmacist, is central to optimizing patient adherence. However, the most realistic approach is to keep in mind that non-adherence is always possible, indeed, probable.
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“Previous studies suggested that the misuse or rejection of medication or NIV can be influenced by some psychological factors such as anxiety, depression, health beliefs, and cognitive impairment (27–29); the unacknowledged recognition of the illness; and the use of different devices and medications due to comorbidities (30–32).”
From Promoting Acceptance and Adherence to Noninvasive Ventilation in Chronic Obstructive Pulmonary Disease: A Randomized Controlled Trial. (2022) · cites this paper as [29]
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Cites
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974
Adherence to Long-Term Therapies: Evidence for Action
Geest, S. D., & Sabate, E. J. (2003) · European Journal of Cardiovascular Nursing · doi:10.1016/s1474-5151(03)00091-4 · Cited by 6,310
Adherence to Long‐Term Therapies: Evidence for Action
Burkhart, P. V., & Sabaté, E. (2003) · Journal of Nursing Scholarship · doi:10.1111/j.1547-5069.2003.tb00001.x · Cited by 2,526
A new taxonomy for describing and defining adherence to medications
Vrijens, B., De Geest, S., Hughes, D. A., Przemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., et al. (2012) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.2012.04167.x · Cited by 2,028
Adherence to inhaled therapy, mortality and hospital admission in COPD
Vestbo, J., Anderson, J. A., Calverley, P. M. A., Celli, B., Ferguson, G. T., Jenkins, C., Knobil, K., Willits, L. R., Yates, J. C., & Jones, P. W. (2009) · Thorax · doi:10.1136/thx.2009.113662 · Cited by 516
Bourbeau, J., & Bartlett, S. J. (2008) · Thorax · doi:10.1136/thx.2007.086041 · Cited by 490
Patient Characteristics Associated with Medication Adherence
Rolnick, S. J., Pawloski, P. A., Hedblom, B. D., Asche, S. E., & Bruzek, R. J. (2013) · Clinical Medicine & Research · doi:10.3121/cmr.2013.1113 · Cited by 481
Integrated care prevents hospitalisations for exacerbations in COPD patients
Casas, A., Troosters, T., Garcia-Aymerich, J., Roca, J., Hernández, C., Alonso, A., del Pozo, F., de Toledo, P., Anto, J. M., Rodríguez-Roisín, R., et al. (2006) · European Respiratory Journal · doi:10.1183/09031936.06.00063205 · Cited by 469
Treatment of COPD: Relationships between daily dosing frequency, adherence, resource use, and costs
Toy, E. L., Beaulieu, N. U., McHale, J. M., Welland, T. R., Plauschinat, C. A., Swensen, A. R., & Duh, M. S. (2010) · Respiratory Medicine · doi:10.1016/j.rmed.2010.09.006 · Cited by 283
Objective Assessment of Adherence to Inhalers by Patients with Chronic Obstructive Pulmonary Disease
Sulaiman, I., Cushen, B., Greene, G., Seheult, J. N., Seow, D., Rawat, F., MacHale, E., Mokoka, M., Moran, C. N., Sartini-Bhreathnach, A., et al. (2016) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201604-0733oc · Cited by 224
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- Rolnick, 2013, Patient characteristics associated with medication adherence, Clin. Med. Res., 11, 54, 10.3121/cmr.2013.1113 · DOI
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Items 101–102 of 102
Smoking cessation and depression risk in newly diagnosed COPD patients: A nationwide cohort study
Doo, J. H., Yu, J., Park, S. J., Sm, P., Chung, J., Kang, J. H., Han, C., Park, S. M., & Shin, H. (2026) · Respiratory Medicine · doi:10.1016/j.rmed.2026.109050
Deciphering the Benefits and Risks of Single-Inhaler Triple Therapy in COPD
Kopitović, I., Dimić-Janjić, S., Stjepanović, M., Hromiš, S., Zvezdin, B., Ilic, M. P., Kolarov, V., Milić, R., Čekerevac, I., Ćupurdija, V., et al. (2026) · Advances in respiratory medicine · doi:10.3390/arm94050070
“These findings are plausible because adherence to inhaled therapy is often poor and tends to decline as regimen complexity increases [56,57].”
Metadata
- Authors
- Rogliani, P., Ora, J., Puxeddu, E., Matera, M. G., & Cazzola, M.
- Affiliations
- University of Rome Tor Vergata (IT)
- Policlinico Tor Vergata (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Corresponding author
- Cazzola, Mario
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 129
- Pages
- 117-123
- ISSN
- 0954-6111 (ISSN-L)
- OpenAlex
- W2624975405
- Cited by
- 102
- References
- 46
- Citations by year
- 2026: 9 · 2025: 4 · 2024: 16 · 2023: 20 · 2022: 11 · 2021: 14 · 2020: 12 · 2019: 7 · 2018: 5 · 2017: 4
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli" (submittedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Chronic Obstructive Pulmonary Disease (COPD) Research
- Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
- Keywords
- chronic obstructive pulmonary disease, medication adherence, non-compliance, pharmacotherapy, patient beliefs, polypharmacy, social support, access to medicines
- MeSH terms
- Assessment of Medication Adherence, Administration, Inhalation, Adrenal Cortex Hormones, Adrenergic beta-Agonists, Classification, Communication, Female, Humans, Health Knowledge, Attitudes, Practice, Male, Pharmacists, Physicians, Social Support, Survival Analysis, Drug Monitoring, Pulmonary Disease, Chronic Obstructive, Medication Adherence, Self Report
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