The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.
Molecular dynamics simulations of large macromolecular complexes
Open accessAbstract
Connecting dynamics to structural data from diverse experimental sources, molecular dynamics simulations permit the exploration of biological phenomena in unparalleled detail. Advances in simulations are moving the atomic resolution descriptions of biological systems into the million-to-billion atom regime, in which numerous cell functions reside. In this opinion, we review the progress, driven by large-scale molecular dynamics simulations, in the study of viruses, ribosomes, bioenergetic systems, and other diverse applications. These examples highlight the utility of molecular dynamics simulations in the critical task of relating atomic detail to the function of supramolecular complexes, a task that cannot be achieved by smaller-scale simulations or existing experimental approaches alone.
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Cited by
Bringing Molecular Dynamics Simulation Data into View
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Advances in coarse-grained modeling of macromolecular complexes
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Current limitations of solid-state NMR in carbohydrate and cell wall research
Zhao, W., Deligey, F., Chandra Shekar, S., Mentink-Vigier, F., & Wang, T. (2022) · Journal of Magnetic Resonance · doi:10.1016/j.jmr.2022.107263 · Cited by 35
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Metadata
- Authors
- Perilla, J. R., Goh, B. C., Cassidy, C. K., Liu, B., Bernardi, R. C., Rudack, T., Yu, H., Wu, Z., & Schulten, K.
- Venue
- Current Opinion in Structural Biology
- Publisher
- Elsevier BV
- Published
- 2015-04
- Volume
- 31
- Pages
- 64-74
- ISSN
- 0959-440X (ISSN-L)
- OpenAlex
- W2098055048
- Cited by
- 420
- References
- 97
- FWCI
- 3.76
- Type
- journal article
- Language
- en
- Open access
- green
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- Perilla, J. R., Goh, B. C., Cassidy, C. K., Liu, B., Bernardi, R. C., Rudack, T., Yu, H., Wu, Z., & Schulten, K. (2015). Molecular dynamics simulations of large macromolecular complexes. Current Opinion in Structural Biology. https://doi.org/10.1016/j.sbi.2015.03.007
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